• Title/Summary/Keyword: optimal experimental design

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Biomechanical evaluations of the long-term stability of dental implant using finite element modeling method: a systematic review

  • Hosseini-Faradonbeh, Seyed Aref;Katoozian, Hamid Reza
    • The Journal of Advanced Prosthodontics
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    • v.14 no.3
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    • pp.182-202
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    • 2022
  • PURPOSE. The aim of this study is to summarize various biomechanical aspects in evaluating the long-term stability of dental implants based on finite element method (FEM). MATERIALS AND METHODS. A comprehensive search was performed among published studies over the last 20 years in three databases; PubMed, Scopus, and Google Scholar. The studies are arranged in a comparative table based on their publication date. Also, the variety of modeling is shown in the form of graphs and tables. Various aspects of the studies conducted were discussed here. RESULTS. By reviewing the titles and abstracts, 9 main categories were extracted and discussed as follows: implant materials, the focus of the study on bone or implant as well as the interface area, type of loading, element shape, parts of the model, boundary conditions, failure criteria, statistical analysis, and experimental tests performed to validate the results. It was found that most of the studied articles contain a model of the jaw bone (cortical and cancellous bone). The material properties were generally derived from the literature. Approximately 43% of the studies attempted to examine the implant and surrounding bone simultaneously. Almost 42% of the studies performed experimental tests to validate the modeling. CONCLUSION. Based on the results of the studies reviewed, there is no "optimal" design guideline, but more reliable design of implant is possible. This review study can be a starting point for more detailed investigations of dental implant longevity.

Optimization of Mixing Condition of Cabbage Cream Soup (쌀가루를 첨가한 양배추 크림수프의 제조조건 최적화)

  • Park, So-Yeon;Pyo, Seo-Jin;Joo, Na-Mi
    • Journal of the Korean Society of Food Culture
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    • v.25 no.1
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    • pp.54-60
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    • 2010
  • The principal objective of this study was to determine the optimal mixing condition of two different amounts of cabbage and rice flour for the preparation of a cabbage cream soup. The experimental design was based on the central composite design methodology of response surface, which included 10 experimental points, including two replicates for the cabbage and rice flour. Physiochemical and sensory properties were measured, and these values were applied to the mathematical models. A canonical form and perturbation plot showed the influence of each ingredient on the mixed final product. Water content and pH values increased with increasing quantities of rice flour. Neither cabbage or rice flour affected the L and a values, but the b value increased with greater quantity of both ingredients. Viscosity increased with increasing added cabbage. Sensory evaluation results were significant in the predicted model for flavor (p<0.05), concentration (p<0.01) and overall quality (p<0.01). As a result, the optimum formulations by numerical and graphical methods were calculated as 111.79 g cabbage and 8.99 g rice flour.

Statistical Optimization of Medium Components for Milk-Clotting Enzyme Production by Bacillus amyloliquefaciens D4 Using Wheat Bran-an Agro-Industry Waste

  • Zhang, Weibing;He, Xiaoling;Liu, Hongna;Guo, Huiyuan;Ren, Fazheng;Gao, Weidong;Wen, Pengcheng
    • Journal of Microbiology and Biotechnology
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    • v.23 no.8
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    • pp.1084-1091
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    • 2013
  • In this paper, two statistical methods were applied to optimize medium components to improve the production of the milk-clotting enzyme by Bacillus amyloliquefaciens D4. First, wheat bran juice, skim milk powder, and $Na_2HPO_4$ were shown to have significant effects on D4 enzyme production using the Plackett-Burman experimental design. Subsequently, an optimal medium was obtained using the Box-Behnken method, which consisted of 3.31 g/l of skim milk powder, 5.0 g/l of sucrose, 0.1 g/l of $FeSO_4{\cdot}7H_2O$, 0.1 g/l of $MgSO_4{\cdot}7H_2O$, 0.1 g/l of $MnSO_4{\cdot}2H_2O$, 0.1 g/l of $ZnSO_4{\cdot}7H_2O$, 1.52 g/l of $Na_2HPO_4$, and 172.45 g/l of wheat bran juice. With this optimal medium, the milk-clotting enzyme production was remarkably enhanced. The milk-clotting enzyme activity reached 3,326.7 SU/ml after incubation of 48 h, which was 1.76-fold higher than that of the basic medium, showing that the Plackett-Burman design and Box-Behnken response surface method are effective to optimize medium components, and B. amyloliquefaciens D4 possessed a high rennet-producing capacity in the optimal medium.

Optimal Temperature and Light Intensity for Improved Mixotrophic Metabolism of Chlorella sorokiniana Treating Livestock Wastewater

  • Lee, Tae-Hun;Jang, Jae Kyung;Kim, Hyun-Woo
    • Journal of Microbiology and Biotechnology
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    • v.27 no.11
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    • pp.2010-2018
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    • 2017
  • Mixotrophic microalgal growth gives a great premise for wastewater treatment based on photoautotrophic nutrient utilization and heterotrophic organic removal while producing renewable biomass. There remains a need for a control strategy to enrich them in a photobioreactor. This study performed a series of batch experiments using a mixotroph, Chlorella sorokiniana, to characterize optimal guidelines of mixotrophic growth based on a statistical design of the experiment. Using a central composite design, this study evaluated how temperature and light irradiance are associated with $CO_2$ capture and organic carbon respiration through biomass production and ammonia removal kinetics. By conducting regressions on the experimental data, response surfaces were created to suggest proper ranges of temperature and light irradiance that mixotrophs can beneficially use as two types of energy sources. The results identified that efficient mixotrophic metabolism of Chlorella sorokiniana for organics and inorganics occurs at the temperature of $30-40^{\circ}C$ and diurnal light condition of $150-200{\mu}mol\;E{\cdot}m^{-2}{\cdot}s^{-1}$. The optimal specific growth rate and ammonia removal rate were recorded as 0.51/d and 0.56/h on average, respectively, and the confirmation test verified that the organic removal rate was $105mg\;COD{\cdot}l^{-1}{\cdot}d^{-1}$. These results support the development of a viable option for sustainable treatment and effluent quality management of problematic livestock wastewater.

Designing Desulfurization Reactor by Numerical Modeling including Desulfurization, Regeneration Processes, and Adsorption Rate Estimation (탈황, 재생공정 및 흡착속도 추정을 포함한 디젤용 탈황반응기 설계)

  • Choi, Chang Yong;Im, Do Jin
    • Korean Chemical Engineering Research
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    • v.55 no.6
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    • pp.874-880
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    • 2017
  • In this study, we performed numerical simulation of the adsorptive desulfurization reactor for a 100 kW fuel cell. Using experimental results and the adsorption kinetics theory, the adsorption rate of sulfur in diesel was estimated and verified by numerical analysis. By analyzing the performance of desulfurization according to reactor size, the optimal reactor size was determined. By maximizing processed diesel amount, optimal diesel flow rate was determined. Regeneration process was also confirmed for the obtained optimal reactor size. The present work will be utilized to design a diesel desulfurization reactor for a fuel cell used in a ship by further process modeling and economic analysis.

Ram Accelerator Optimization Using the Response Surface Method (반응면 기법을 이용한 램 가속기 최적설계에 관한 연구)

  • Jeon Yong-Hee;Jeon Kwon-Su;Lee Jae-Woo;Byun Yung-Hwan
    • 한국전산유체공학회:학술대회논문집
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    • 2000.05a
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    • pp.159-165
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    • 2000
  • In this paper, numerical study has been done for the improvement of the superdetonative ram accelerator performance and for the design optimization of the system. The objective function to optimize the premixture composition is the ram tube length required to accelerate projectile from initial velocity $V_o$ to target velocity $V_e$. The premixture is composed of $H_2,\;O_2,\;N_2$ and the mole numbers of these species are selected at design variables. RSM(Response Surface Methodology) which is widely used for the complex optimization problems is selected as the optimization technique. In particular, to improve the non-linearity of the response and to consider the accuracy and efficiency of the solution, design space stretching technique has been applied. Separate sub-optimization routine is introduced to determine the stretching position and clustering parameters which construct the optimum regression model. Two step optimization technique has been applied to obtain the optimal system. With the application of stretching technique, we can perform system optimization with a small number of experimental points, and construct precise regression model for highly non-linear domain. The error to compared with analysis result is only $0.01\%$ and it is demonstrated that present method can be applied more practical design optimization problems with many design variables.

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A Study on the Disk Vibration Control by Disk Damper For 100kTPI Hard Disk Drive Design (100KTPI급 HDD 구현을 위한 DISK DAMPER에 관한 연구)

  • Han, Y.S.;Kang, S.W.;Oh, D.H.;Hwang, T.Y.;Tran, Greg
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2002.11b
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    • pp.363-368
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    • 2002
  • A practical implementation method of squeeze-film aeroelastic disk vibration damping and its practical design performance are presented to provide a solution method to meet the tight TMR(Track Mis-Registration) design budget of high-TPI HDDs. Most previous research results are mainly based on the component-level study in the 'open-cover state' which is far from the realistic operation HDD condition. In this study, the squeeze-film disk damping effect is widely investigated under the realistic drive-level condition of 'enclosed-cover state.' It is found that the proper aeroelastic gap(s) between disk(s) and adjacent surface(s) to give significant vibration reduction in the enclosed HDD operating conditions can be achieved not only by classical well-known squeeze-film damping gaps such as very small 0.0x-millimeter level gaps which are not practically implementable in mass-production HDDs, but also by a few 0.x millimeter which is possible for designing realistic HDD design. The various experimental results including drive-level PES are also presented to prove feasibility of the optimal disk damper design for 93kTPI HDDs.

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An Experimental Examination of Customer Preferences on Mobile Interfaces (모바일 서비스 고객선호도에 관한 실증연구)

  • Baek, Seung-Ik;Cho, Min;Kim, Bong-Jun
    • Korean Management Science Review
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    • v.23 no.3
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    • pp.27-39
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    • 2006
  • Designing mobile Interfaces is fundamentally different from designing online interfaces. Not only are there differences in underlying technologies, but also in the way people use mobile Interfaces. If these differences are not taken into account in designing mobile interfaces, mobile services are likely to fail. If mobile services do not deliver what people want, these services will fail no matter how excellent the underlying technology is. The user interface design commonly used in mobile services is based on multi-layered approach, which is not very user-friendly. A well designed single layered user Interface will be more user friendly than the conventional one and it will be having edge over others. However, it is quite difficult to Provide a single layered user Interface in a small screen. This study aims at examining how design attributes of mobile interfaces affect customer preferences. In order to explore customer preferences to each design attribute of mobile interfaces, we measure and analyze customer's WTP (Willingness To Pay) toward their different interface designs. Ultimately, throughout the study, we try to answer how to design mobile interfaces in small screen of mobile devices. In addition, we propose an optimal design solution that customers likely prefer.

Flow Analysis of Water Pump for Clean Disel Engine Application (클린 디젤엔진용 워터펌프 유동해석)

  • Lee, Dongju;Kim, Taeyoung;Chon, Mun Soo
    • Journal of Institute of Convergence Technology
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    • v.4 no.2
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    • pp.61-65
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    • 2014
  • Pressure distribution around rotating impeller blades in centrifugal pump has been main issue for design of efficient and high performance automotive water pump. In addition, pressure losses of inlet water pipes should be considered to reduce additional pressure drop and design high performance engine cooling system. In this paper, pressure distribution inside water pump and pressure drop between inlet and outlet of water pump are investigated numerically to design plastic water pump for clean diesel engine application. And the inlet geometry of water pump was considered to analysis the effect of inlet water pipe geometry on pressure distribution around impeller blades and outlet pressure. The prediction results are compared with experimental data to validate and determine optimal operation condition without water pump cavitation. Major design parameters such as blade angle, volute geometry, system pressure, and coolant flow rate are considered to confirm applying possibility of plastic blades to the clean diesel engine.

Ram Accelerator Optimization Using the Response Surface Method (반응면 기법을 이용한 램 가속기 최적설계에 관한 연구)

  • Jeon Kwon-Su;Jeon Yong-Hee;Lee Jae-Woo;Byun Yung-Hwan
    • Journal of computational fluids engineering
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    • v.5 no.2
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    • pp.55-63
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    • 2000
  • In this paper, the numerical study has been done for the improvement of the superdetonative ram accelerator performance and for the design optimization of the system. The objective function to optimize the premixture composition is the ram tube length, required to accelerate projectile from initial velocity V/sub 0/ to target velocity V/sub e/. The premixture is composed of H₂, O₂, N₂ and the mole numbers of these species are selected as design variables. RSM(Response Surface Methodology) which is widely used for the complex optimization problems is selected as the optimization technique. In particular, to improve the non-linearity of the response and to consider the accuracy and the efficiency of the solution, design space stretching technique has been applied. Separate sub-optimization routine is introduced to determine the stretching position and clustering parameters which construct the optimum regression model. Two step optimization technique has been applied to obtain the optimal system. With the application of stretching technique, we can perform system optimization with a small number of experimental points, and construct precise regression model for highly non-linear domain. The error compared with analysis result is only 0.01% and it is demonstrated that present method can be applied to more practical design optimization problems with many design variables.

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