• 한국실내디자인학회:학술대회논문집
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• 한국실내디자인학회 2007년도 추계학술발표대회 논문집
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• pp.67-72
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• 2007

Recently designed residence complexes, there is an increasing interest in qualitative and quantitative improvement of not only the primary function of the residence, but also the community facilities designed for the convenience and welfare of its residents. Among such community facilities, an apartment's playground for children still remains in a traditional form and lacks the versatility required to satisfy the needs and interests of modern children, especially an age diverse child population. Therefore, this study intends to analyze the status of children's play facilities as community spaces, analyze the community's satisfaction with them, and suggest alternatives to the limited functions of children's play facilities in order to improve opportunities for neighbors to meet and build a stronger community.

• 한국건축시공학회지
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• 제3권4호
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• pp.95-102
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• 2003

A construction project's period is limited by the order manufacture. And a construction project is requested a specific place, and has the characteristic to be irregular. Today, construction is to be representative high-cost and low-efficiency. This kind of problems appears in small construction projects more often than large construction projects. According to this facts, we recognized necessity of making practical application in methods of construction management. Also, we suggest application and establishment of integrated responsibility management department, PMIS(Project Management Information System) and Data Base. From now on, methods of construction management could be good opportunities for small construction projects and local construction companies. Therefore, small and local construction companies should try to improve their abilities. Likewise, the countries systematize to constitute the relation laws.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제16권1호
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• pp.173-187
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• 2022

Recent studies have focused on self-management of hypertension using smart devices (cellular phones, tablets, watches). It has proven to be an effective tool for early detection and control of high Blood Pressure (BP) without affecting patients' daily routines. This systematic review surveys the existing self-monitoring systems, evaluate their effectiveness and compares the different approaches. We investigated the current systems in terms of various attributes, including methods used, sample size, type of investigation, inputs/ outputs, rate of success in controlling BP, group of users with higher response rate and beneficiaries, acceptability, and adherence to the system. We identified some limitations, shortcomings, and gaps in the research conducted recently studying the impact of mobile technology on managing hypertension. These shortcomings can generate future research opportunities and enable it to become more realistic and adaptive. We recommended including more observable factors and human behaviors that affect BP. Furthermore, we suggested that vital monitoring/logging and medication tuning are insufficient to improve hypertension control. There is also a need to observe and alter patient behavior and lifestyles.

• Journal of Ecology and Environment
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• 제47권2호
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• pp.27-34
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• 2023

Background: The understanding of ecosystem services can be quantified and qualitative to assess the impacts of changes in the ecosystem to support human well-being. In the Democratic People's Republic of Korea, sustainable use of ecosystem services has attracted the interest of a range of decision-makers. However, although there is a concern for biodiversity, natural ecosystem, and their services, linking ecosystems with conservation planning remains challenging. Results: This study assessed the first qualitative ecosystem services provided by the Mundok wetland with decision makers of the West/Yellow Sea region. Furthermore, this study applied the Rapid Assessment Wetland Ecosystem method to support natural resources management, improving living conditions. We identified that cultural and supporting services index are highly provided, but preparing a plan to increase the provisioning and regulating services in Mundok wetland is necessary. Conclusions: The assessment results can provide helpful information for ecosystem services assessment, habitat conservation, conservation planning, and decision-making at local level.

• Biomolecules & Therapeutics
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• 제32권1호
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• pp.13-24
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• 2024

Cytokines influence the overall cancer immune cycle by triggering tumor antigen expression, antigen presenting, immune cell priming and activation, effector immune cell recruitment and infiltration to cancer, and cancer killing in the tumor microenvironment (TME). Therefore, cytokines have been considered potential anti-cancer immunotherapy, and cytokine-based anti-cancer therapies continue to be an active area of research and development in the field of cancer immunotherapy, with ongoing clinical trials exploring new strategies to improve efficacy and safety. In this review, we examine past and present clinical developments for major anticancer cytokines, including interleukins (IL-2, IL-15, IL-12, IL-21), interferons, TGF-beta, and GM-CSF. We identify the current status and changes in the technology platform being applied to cytokine-based immune anti-cancer therapeutics. Through this, we discuss the opportunities and challenges of cytokine-based immune anti-cancer treatments in the current immunotherapy market and suggest development directions to enhance the clinical use of cytokines as immuno-anticancer drugs in the future.

• Journal of the Korean Institute of Landscape Architecture International Edition
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• 제1호
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• pp.120-126
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• 2001

The Haidian Garden of Zhongguancun Science and Technology Zone is an area with high intellectual intensity. It is therefore known as China's Silicon Valley. The Summer Palace, a World Heritage Site, sits in the northwest part of it. 250 years ago, the construction of imperial gardens in this area, including the Summer Palace, gave birth to the appearance and prosperity of the town of Haidian. This will also provide various opportunities for the growth of the science and technology. Today the green space, the cultural and ecological environment of the Summer Palace, and its 3-kilometer buffer zone are becoming one important strategic factor for the Haidian Garden to attract talents, improve international competitiveness and realize sustainable development. How to taking advantage of the favorable resources, to achieve balance between protection of the environment around the Summer Palace and urban development, will be of great importance in the future plans of the science and technology.

• BMB Reports
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• 제52권5호
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• pp.324-329
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• 2019

Recent progress in cellular reprogramming technology and lineage-specific cell differentiation has provided great opportunities for translational research. Because virus-based gene delivery is not a practical reprogramming protocol, protein-based reprogramming has been receiving attention as a safe way to generate reprogrammed cells. However, the poor efficiency of the cellular uptake of reprogramming proteins is still a major obstacle. Here, we reported key factors which improve the cellular uptake of these proteins. Purified red fluorescent proteins fused with 9xLysine (dsRED-9K) as a cell penetrating peptide were efficiently delivered into the diverse primary cells. Protein delivery was improved by the addition of amodiaquine. Furthermore, purified dsRED-9K was able to penetrate all cell lineages derived from mouse embryonic stem cells efficiently. Our data may provide important insights into the design of protein-based reprogramming or differentiation protocols.

• 국제학술발표논문집
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• The 6th International Conference on Construction Engineering and Project Management
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• pp.41-43
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• 2015

Urban Informatics, the application of data science methodologies to the urban development and planning domain, has been increasingly adopted to improve the management and efficiency of cities. This paper introduces state of the art use cases in major cities including New York, London, Seoul and Amsterdam. It also introduces recent advances in using Big Data by multi-lateral institutions for poverty reduction, and startups utilizing open data initiatives to create new value and insights. Preliminary research performed on using Seoul's open data such as building permit data and health code violations are also introduced to demonstrate opportunities in this relatively new but promising area of research.

• 한국과학교육학회지
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• 제36권2호
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• pp.337-346
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• 2016

무한상상실은 국민의 창의적인 아이디어가 과학기술과 결합하여 창업과 신산업 및 신시장 창출로 연결되고, 일자리를 창출하기 위해 건립되었다. 국민의 상상력과 창의력을 현실화시킬 수 있는 공간 조성이 필요하다는 인식하에 현재까지 58개소가 설치 운영중이며 지속적으로 확대되는 추세에 있다. 3D 프린터와 레이저 커터기 등 다양한 첨단기기들이 비치되어 아이디어를 프로토타입으로 제작하기 위한 시설을 갖추고 있다. 본 연구에서는 온라인 설문 조사와 면대면 인터뷰를 통해 무한상상실에서 이용자의 경험을 조사했다. 그 후, 우리는 무한상상실에서 이용자들이 아이디어를 생성하기 위한 동기 부여, 흥미에 대해 무한상상실을 사용하여 관련 기술뿐만 아니라 문제에 대한 해결방안을 제시했다. 결과를 기반으로 무한상상실의 효율적인 운영 방안에 대한 세 가지 제언을 할 수 있었다. 첫째, 무한상상실을 이용자들을 위한 교수학습 지원을 확대해야 한다. 둘째, 무한상상실 교수자를 위한 별도의 전문적인 교육 프로그램 개발이 필요하다. 셋째, 이용자들의 특성에 맞춘 편의를 제공하는 창의적인 서비스 도입을 추진해야 한다.

• 한국전자통신학회논문지
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• 제16권5호
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• pp.909-916
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• 2021

3D 프린터는 개인의 창의력을 실제로 구현할 수 있는 장점이 있다. 이 특성을 활용하려는 사람들은 증가하고 있지만 적합한 프린팅 교육의 기회 부족과 잘못된 출력 방법으로 문제 발생의 어려움을 겪는다. 따라서 저하된 출력물 품질이 사용자의 관심을 낮춰 점차 3D 프린터의 활용빈도 수를 감소시키게 된다. 본 연구에서는 3D 프린터의 오작동 해결과 편의성의 개선을 위해 직접 기기를 작동하면서 발생하는 문제를 파악하고 분석했다. 여러 문제점 중 안착 불량, 스트링 현상, 노즐 막힘을 중점으로 해결과 완화 연구를 진행하였다. 또한, 3D 프린터의 기능을 실험을 통해 재료소모량 감소와 출력시간 단축 방법을 고찰했다. 최종적으로 3D 프린팅 중 빈번하게 발생하는 출력문제를 해결해 외관이 온전한 출력물을 얻을 수 있었고 편의성을 개선하였다.