• Journal of Korean Neurosurgical Society
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• v.48 no.5
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• pp.391-398
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• 2010

Objective : This study was designed to validate the cell trafficking efficiency of the in vivo bioluminescence image (BLI) study in the setting of transplantation of the luciferase expressing bone marrow-derived mesenchymal stem cells (BMSC), which were delivered at each different time after transient middle cerebral artery occlusion (MCAO) in a mouse model. Methods : Transplanting donor BMSC were prepared by primary cell culture from transgenic mouse expressing luciferase (LUC). Transient focal infarcts were induced in 4-6-week-old male nude mice. The experiment mice were divided into five groups by the time of MSC transplantation : 1) sham-operation group, 2) 2-h group, 3) 1-day group, 4) 3-day group, and 5) 1-week group. BLI for detection of spatial distribution of transplanted MSC was performed by detecting emitted photons. Migration of the transplanted cells to the infarcted area was confirmed by histological examinations. Differences between groups were evaluated by paired t-test. Results : A focal spot of bioluminescence was observed at the injection site on the next day after transplantation by Signal intensity of bioluminescence. After 4 weeks, the mean signal intensities of 2-h, 1-day, 3-day, and 1-week group were $2.6{\times}10^7{\pm}7.4{\times}10^6$. $6.1{\times}10^6{\pm}1.2{\times}10^6$, $1.7{\times}10^6{\pm}4.4{\times}10^5$, and $8.9{\times}10^6{\pm}9.5{\times}10^5$, respectively. The 2-h group showed significantly higher signal intensity (p<0.01). The engrafted BMSC showed around the infarct border zones on immunohistochemical examination. The counts of LUC-positive cells revealed the highest number in the 2-h group, in agreement with the results of BLI experiments (p<0.01). Conclusion : In this study, the results suggested that the transplanted BMSC migrated to the infarct border zone in BLI study and the higher signal intensity of LUC-positive cells seen in 2 hrs after MSC transplantation in MCAO mouse model. In addition, noninvasive imaging in real time is an ideal method for tracking stem cell transplantation. This method can be widely applied to various research fields of cell transplantation therapy.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.10
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• pp.2307-2314
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• 2015

This paper focuses on the generation algorithm of BeiDou pseudorange correction (PRC) and simulation based performance verification for design of Differential Global Navigation Satellite System (DGNSS) reference station and integrity monitor (RSIM) in order to prepare for recapitalization of DGNSS. First of all, it discusses the International standard on DGNSS RSIM, based on the interface control document (ICD) for BeiDou, estimates the satellite position using satellite clock offset and user receiver clock offset, and the system time offset between Global Positioning System (GPS) and BeiDou. Using the performance verification platform interfaced with GNSS (GPS/BeiDou) simulator, it calculates the BeiDou pseudorange corrections , compares the results of position accuracy with GPS/DGPS. As the test results, this paper verified to meet the performance of position accuracy for DGNSS RSIM operation required on Radio Technical Commission for Maritime Services (RTCM) standard.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.41 no.10
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• pp.788-795
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• 2013

A magnesium bipolar plate whose surface was protected by thinly deposited silver layer was investigated as an alternative to existing graphite bipolar plate of PEM fuel cells. Thin silver layer of $3{\mu}m$ was deposited on a magnesium alloy substrate by physical vapor deposition (PVD) method in an environment of $180^{\circ}C$. A number of tests were conducted on the fabricated magnesium based bipolar plates to determine their suitability for use in PEM fuel cell stacks. The test on corrosion resistance in the same pH condition as in a PEM operation demonstrated the layer protected the magnesium alloy substrate, while unprotected substrate suffered from severe corrosion. The contact resistance of the fabricated bipolar plate was less than $20m{\Omega}-cm^2$ which was superior to the conventional bipolar plates. A single cell was constructed using the fabricated bipolar plates and power output was measured. Due to the enhanced conductivity caused by low contact resistance, slight increase was observed in current density and output voltage. With low density of the magnesium substrate and ease on machining, the weight reduction of the stack of 30~40 % is possible to produce the same power output.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.45 no.2
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• pp.154-162
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• 2017

CanSat Competition has been annually held in South Korea since 2012 to give students an opportunity for better understanding of system design and operation processes of satellite. SCSky CanSat(Smart Call from the Sky Can Satellite) proposed in this study is a name of CanSat that was participated in 2016 CanSat competition. Its main mission objective is to obtain flight imaging data of inside and outside the CanSat through the video call using on-board smart phone in the CanSat. To implement this mission, we developed a remote touch system using SMA(Shape Memory Alloy) wire. In addition, a wide scan camera mechanism using SMA spring was developed to obtain ground imaging data during the mission. This study introduced the mission of the SCSky CanSat, as well as the description of on-board payloads, system design results, and flight test results.

• Journal of Korea Water Resources Association
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• v.53 no.10
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• pp.871-876
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• 2020

Understanding the wave characteristics near the outlet of coastal power plants for cooling water in the vicinity of the dredged areas is critically important for the construction and operation of the plants. By Employing the eigenfunction expansion method, in this study, we analyzed the reflection of monochromatic water waves over (1) shear currents near the outlet and (2) multi-arrayed trenches representing dredged areas. We firstly optimized the number of grids expressing shear currents and the number of evanescent modes based on a convergence test. We then analyzed the sensitivity of the reflection coefficients depending on (1) magnitude of shear currents, (2) width of shear currents, (3) a distance between adjacent trenches, and (4) a number of trenches. The results showed that the reflection coefficient was more sensitive to the number of trenches and the distance between trenches than the velocity of shear currents and the width of shear currents. We also found that even the effect of shear currents is relatively small, the effect is not negligible in a relative water depth from shallow to near shallow water waves (0.01 < kh ≦ 0.70).

• KIPS Transactions on Computer and Communication Systems
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• v.4 no.4
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• pp.135-140
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• 2015

The WDSS improves defensive capacity against web application layer DDoS attack by using web cache server and L7 switch which are added on the DDoS shelter system. When web DDoS attack occurs, security agents divert traffic from backbone network to sub-network of the WDSS and then DDoS protection device and L7 switch block abnormal packets. In the meantime, web cache server responds only to requests of normal clients and maintains stable web service. In this way, the WDSS can counteract the web DDoS attack which generates small traffic and depletes server-client session resource. Furthermore, the WDSS does not require IP tunneling because it is not necessary to retransfer the normal requests to original web server. In this paper, we validate operation of the WDSS and verify defensive capability against web application layer DDoS attacks. In order to do this, we built the WDSS on backbone network of an ISP. And we performed web DDoS tests by using a testing system that consists of zombie PCs. The tests were performed by three types and various amounts of web DDoS attacks. Test results suggest that the WDSS can detect small traffic of the web DDoS attacks which do not have repeat flow whereas the formal DDoS shelter system cannot.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.12
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• pp.535-545
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• 2019

The PBA of ship weapon system should be installed and operated under harsh environmental conditions and so it should be highly reliable to endure the mission profiles during its entire lifetime. In the case of PBA failure during operation, rapid maintenance is highly likely to be difficult due to problems such as supply of parts, which can have a devastating effect on the mission. In order to validate the reliability of PBA, a series of tests are performed with PBA samples, but they require time, testing facilities, samples, expenses and failure analysis if failed. The reliability of PBA is predicted on the basis of specifications such as MIL-HDBK-217F, but this specification does not take into account failure mechanisms for specific design details, environment and usage, interconnects and its characteristics that drive many failures of PBA in the field. Therefore, this study predicts the reliability of PBA using an RPA tool and proposes the RPA methodology as a validation process at the design stage. With RPA, it is now possible to achieve design validation including inherent failure mechanism, identification of weakest link, alternative design options, and test plan development.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.12
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• pp.102-109
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• 2019

This paper describes the design of the circuit card assembly to eliminate the communication error on a servo control unit installed in the automated resupply vehicle K56. K56 is a weapon system that automates the supply and loading of ammunition on the K-55A1 self-propelled artillery. As the core item responsible for ammunition movement control, the servo control unit is required to have good communication stability and reliability, but the conventional unit has recognized a problem that communication error intermittently occurs, resulting in an emergency stop phenomenon. We analyzed the communication signal of the servo control unit and identified the failure cause of the circuit card assembly to solve this problem. In addition, the signal interference in data/address line of the circuit card assembly was confirmed through analysis of the failure cause, and redesigned to avoid the interference, such as adjustment of the distance between communication lines and position change. Finally, the proposed cause analysis and redesign were verified through the component of servo control unit and attachment test on K56. We expected these study results to be used as reference for the design of other similar items.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.12
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• pp.237-246
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• 2019

The Electro-Mechanical Brake (EMB) is the next generation braking system for automobiles and railway vehicles. Current brake systems for high-speed trains generate a braking force using a pneumatic cylinder, but EMB systems produce that force through a combination of an electric motor and a gear. In this study, an EMB operation mechanism capable of generating a high braking force was proposed, and structural and vibration analyses of the gears and shafts, which are the core parts of the mechanisms, were performed. Dynamic structural analysis confirmed that the maximum stress in the analysis model was within the yield strength of the material. In addition, the design that maximizes the diameter of the motor shaft was found to be advantageous in strength, and large shear stress could be generated in the bolt fixing the gear and eccentric shaft. In addition, a test apparatus that can reproduce the mechanism of the analytical model was fabricated to measure the strain of the fixed bolt part, which is the most vulnerable part. The strain measurement results showed that the error between the analysis and measurement was within 10%, which could verify the accuracy of the analytical model.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.4
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• pp.190-200
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• 2020

This study examined the effectiveness of the 'Youth Technology Transfer Specialist Training Project' for students of natural sciences and engineering colleges implemented using a 2018 revised supplementary budget. The cause and effect research model composed of project satisfaction, results of employment, and start-up. Five factors were developed based on a literature review. A total of 2,363 questionnaires were collected through 66 Industrial-Academic Cooperation Groups participating in the Youth TLO (Technology Licensing Officer) program for an empirical test. SPSS 23.0 was used to analyze the obtained data empirically and verify the hypotheses. The result of the analysis showed that the following five independent factors were significant for the program satisfaction as well as the program satisfaction for the performance of employment and start-up: 1) project operation-related recruitment and selection, 2) training support, and 3) working conditions, 4) control of the project, and 5) activity support. This study verified the level of satisfaction with the program empirically using comprehensive data. In terms of practical implications, improvement of operational programs helps improve program satisfaction, and in turn, results in improvement of employment and start-up of youth to achieve the goals of government.