• 대한지리학회지
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• 제49권5호
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• pp.675-689
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• 2014

본 연구에서는 앙상블 경험적 모드 분해법을 우리나라에 적용하여 봄 시작일을 정의하고, 이에 대한 시 공간적인 변화를 분석하였으며, 봄 시작일의 변동성을 분석하여, 봄 시작일에 영향을 미치는 요인을 파악하였다. 우리나라 평균 봄 시작일은 3월 11일로 나타났고, 연구기간 동안 2.6일/10년으로 빨라졌다. 봄 시작일은 일반적으로 위도와 고도가 높아짐에 따라, 그리고 해안에서 내륙으로 갈수록 늦게 나타났다. 우리나라 봄 시작일에 영향을 미치는 요인을 파악하기 위해 상관분석을 수행하였고, 전구평균기온, 북극진동(Arctic Oscillation, AO), 시베리아 고기압이 우리나라 봄 시작일과 유의한 상관관계를 나타냈다. 봄 시작일에 영향을 미치는 지수들을 대상으로 다중회귀분석을 수행하였고, 세 가지 변수가 모두 입력된 모형은 64.7%의 설명력을 나타냈다. 다중회귀분석의 결과 봄 시작일에 미치는 영향은 전구평균기온이 가장 크고, AO가 그 다음으로 나타났다. 우리나라 봄 시작일에 영향을 미치는 종관적인 요인을 파악하기 위해 기압장 및 바람장을 분석한 결과, 시베리아 고기압, 알류샨 저기압, 상층 기압골의 강도 및 위치에 따른 북풍계열 바람의 강도가 봄 시작일을 결정하는 주요 원인인 것으로 나타났다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권5호
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• pp.2587-2592
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• 2016

Background: Early onset sporadic colorectal cancer (CRC) is a biologically and clinically distinct entity hypothesized to exhibit differences in histological features and microsatellite instability (MSI) as compared to typical onset CRC. This study compared the MSI status, mismatch repair enzyme deficiency and clinicopathological features of early onset (aged ${\leq}45$ years) with controls (>45 years). Materials and Methods: A total of 30 cases and 30 controls were analyzed for MSI status using the Bethesda marker panel. Using antibodies against hMLH1, hMSH2 and hMSH6, mismatch repair protein expression was assessed by immunohistochemistry. Molecular characteristics were correlated with clinicopathological features. Results: The early onset sporadic CRCs were significantly more poorly differentiated tumors, with higher N2 nodal involvement and greater frequency of signet ring phenotype than the typical onset cases. MSI was observed in 18/30 cases, with 12/18 designated as MSI-high (MSI-H) and 6/18 designated as MSI-low (MSI-L). In the control group, 14 patients exhibited MSI, with 7 MSI-H and 7 MSI-L. MSI tumors in both cases and controls exhibited loss of hMLH1, hMSH2 and hMSH6. MSS tumors did not exhibit loss of expression of MMR proteins, except hMLH1 protein in 3 controls. No statistically significant difference was noted in MSI status or expression of MMR proteins in cases versus controls. Conclusions: Microsatellite status is comparable between early and typical onset sporadic CRC patients in Pakistan suggesting that differences in clinicopathological features between these two subsets are attributable to other molecular mechanisms.

• Neonatal Medicine
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• 제18권2호
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• pp.370-373
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• 2011

Citrin deficiency는 염색체 7q21.3의 SLC25A13 유전자 돌연변이에 의해 발생하는 상염색체 열성질환으로 neonatal-onset type II citrullinemia (CTLN2) 및 adult-onset CTLN2로 분류된다. 생후 16일된 여아가 신생아 대사 검사에서 citrullinemia (CTLN)가 의심되었고 혈중 아미노산 분석에서 CTLN 및 고암모니아혈증을 보였고, SLC25A13 유전자 분석 결과 c.221C>T in exon4 and c.1645C in exon16 (p.[Ser74Phe]+[Gln549X]) 의 새로운 돌연변이가 발견되어 neonatal-onset CTLN2로 진단되었다. 저자들은 신생아 대사 검사에서 citrullinemia를 보이는 영아들에서 확진을 위한 유전자 검사 및 혈중 아미노산 분석이 필요하다고 생각한다.

• 한국항공우주학회지
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• 제34권5호
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• pp.12-18
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• 2006

고속 항공기의 천음속 버펫 발단을 예측할 수 있는 새로운 정상 접근 방법을 개발하였다. 본 논문에서는 버펫 발단까지 정상 유동장으로 가정하였다. 본 연구는 다양한 정적 공력 변수들의 급격한 변화 분석을 포함하고 있다. 이러한 급격한 변화는 천음속 버펫의 발단을 지시한다. 본 연구에서 고려된 다양한 공력 변수 가운데 압력 중심점 변화가 가장 명확한 천음속 충격파 버펫 발단 지시자임을 보여준다. 이러한 새로운 정상 접근 방법은 박리기포를 수반하는 익형이나 큰 후퇴각과 작은 종횡비를 갖는 날개의 천음속 버펫 발단 예측에 적용할 수 있다. 버펫 시험결과와 비교하여 좋은 일치를 얻었다. 새로운 정적 접근 방법 결과를 기초로, 압력 중심점 변화 곡선의 급격한 기울기 변화는 항공기 전 기체 형상에 대한 정상 시험 방법 버펫 발단 지시자로 새롭게 제시할 수 있다.

• 생물정신의학
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• 제19권1호
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• pp.65-69
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• 2012

Objectives : Much is still unknown about the neurophysiological mechanisms or dynamics of the sleep onset process. Detrended fluctuation analysis (DFA) is a new tool for the analysis of electroencephalography (EEG) that may give us additional information about electrophysiological changes. The purpose of this study is to analyze long-range correlations of electroencephalographic signals by DFA and their changes in the sleep onset process. Methods : Thirty channel EEG was recorded in 61 healthy subjects (male:female=34:27, age=$27.2{\pm}3.0$ years). The scaling exponents, alpha, were calculated by DFA and compared between four kinds of 30s sleep-wakefulness states such as wakefulness, transition period, early sleep, and late sleep (stage 1). These four states were selected by the distribution of alpha and theta waves in O1 and O2 electrodes. Results : The scaling exponents, alpha, were significantly different in the four states during sleep onset periods, and also varied with the thirty leads. The interaction between the sleep states and the leads was significant. The means (${\pm}$ standard deviation) of alphas for the states were 0.94 (${\pm}0.12$), 0.98 (${\pm}0.12$), 1.10 (${\pm}0.10$), 1.07 (${\pm}0.07$) in the wakefulness, transitional period, early sleep and late sleep state respectively. The mean alpha of anterior fifteen leads was greater than that of posterior fifteen leads, and the two regions showed the different pattern of changes of the alpha during the sleep onset periods. Conclusions : The characteristic findings in the sleep onset period were the increasing pattern of scaling exponent of DFA, and the pattern was slightly but significantly different between fronto-temporal and parieto-occipital regions. It suggests that the long-range correlations of EEG have a tendency of increasing from wakefulness to early sleep, but anterior and posterior brain regions have different dynamical process. DFA, one of the nonlinear analytical methods for time series, may be a useful tool for the investigation of the sleep onset period.

• 대한물리의학회지
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• 제10권2호
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• pp.55-61
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• 2015

PURPOSE: The purpose of this study was to investigate recruiting order and onset time around shoulder muscle during the push-up according to the body tilting angle. METHODS: Twenty healthy young adult subjects were recruited for this study. They had no neurological and musculoskeletal disease. We used the sEMG for recording onset time of shoulder muscles. Shoulder Muscles were anterior deltoid(AD), posterior deltoid(PD), pectoralis major(PM), upper trapezius(UT). Body tilting angle were measured at 0 degree, 30 degree and 60 degree by using tilting table. Muscles contraction onset time were set by the push-up performed 3 times respectively. Mean of 3 measurements were used. And initiate onset time was decided by the Mean ${\pm}2$ SD in the threshold, more than 25ms. RESULTS: There were significant difference at 0 degree, 30 degree and 60 degree(p<.05). Muscles onset time were same order at 0 degree, 30 degree. UT occurred first of all contraction at 0 degree and 30 degree. And then contracted AD, PD, PM. But, at 60 degree, AD was the first contraction, and PM, UT, PD. CONCLUSION: Muscle recruitment order and onset time according to the body tilting was shown the difference when you do push-up. Therefore, this result, shoulder muscle recruitment pattern of according to the body tilting is different and it has to make effective shoulder exercise program.

• 정형스포츠물리치료학회지
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• 제14권2호
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• pp.55-64
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• 2018

Purpose : The purpose of this study was to investigate the effect of the sprinter and skater combined patterns on muscle contraction onset time and muscle activation of body stabilizing muscles. Method : Our study included young and healthy men in their 20s. The participants used the sprinter and skater combined patterns of the proprioceptive neuromuscular facilitation (PNF) methods to measure muscle activation and muscle contraction onset time of the trunk muscles. To measure muscle contraction onset time and muscle activation, electrodes were attached to the rectus abdominis (RA), external oblique (EO), internal oblique (IO), and erector spinalis (ES) regions. Significant differences were identified using a paired t-test and a one-way analysis of variance (ANOVA) analysis. Result : In the sprinter combined pattern, the muscle with the fastest onset time of contraction was the RES, and that with the slowest was the RRA (p<.001). In the skater combined pattern, the muscle with the fastest onset time of contraction was the LES, and that with the slowest was the LRA (p<.001). In the sprinter combined pattern, the REO and LIO presented medium muscle contraction onset times (p<.001). In the skater combined pattern, the LEO and RIO presented medium muscle contraction onset times (p<.001). Conclusions: Based on these results, these patterns could be used as exercise methods for the elderly with delayed proactive response speeds of the body stabilization methods due to imbalances in body stabilizing muscles or limbs movement.

• PNF and Movement
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• 제18권3호
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• pp.375-382
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• 2020

Purpose: The purpose of this study was to investigate the muscle contraction onset time characteristics of the gluteus maximus, semitendinosus, and biceps femoris muscles at different knee flexion angles in individuals with shortened or over-lengthened hamstrings performing prone hip extension. Methods: Twenty-six participants were divided into a hamstring shortened group (n = 12) and hamstring lengthened group (n = 14). Wireless surface electromyography was used to verify the muscle onset time of the gluteus maximus, semitendinosus, and biceps femoris when performing prone hip extension at different knee flexion angles. Results: There were significant differences in the muscle onset times of the semitendinosus and biceps femoris between the hamstring shortened group and hamstring lengthened group (p < 0.05). In addition, there was a significant difference in the muscle contraction onset times among of the gluteus maximus, semitendinosus, and biceps femoris muscles when performing prone hip extension at a knee flexion of 90° in the hamstring shortened group (p < 0.05) and a knee flexion angle of 0° in the hamstring lengthened group (p < 0.05). Conclusion: In all groups, there was no effect on the onset time of the gluteus maximus muscle according based on the knee angle. In addition, the knee flexion angles affected the onset time of the muscle contraction of the gluteus maximus muscle in the hamstring shortened group and hamstring lengthened group with an abnormal length of the hamstring muscle.

• 한국HCI학회:학술대회논문집
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• 한국HCI학회 2009년도 학술대회
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• pp.1075-1080
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• 2009

이 글은 Music Information Retrieval(MIR) 기법을 사용하여 오디오 콘텐츠의 리듬 정보를 자동으로 분석하고 이를 시각화하는 방법에 대해 다룬다. 특히 MIR을 활용한 간단한 시각화(sound visualization) 어플리케이션을 소개함으로써 음악 정보 분석이 디자인, 시각 예술에서 다양하게 활용될 수 있음을 보이고자 한다. 음악적 정보를 시각 예술로 담아내려는 시도는 20세기 초 아방가르드 화가들에 의해 본격적으로 시작되었다. 80년대 이후에는 컴퓨터 기술의 급속한 발전으로 사운드와 이미지를 디지털 영역에서 쉽게 하나로 다룰 수 있게 되었고, 이에 따라 다양한 오디오 비주얼 예술작품들이 등장하였다. MIR은 오디오 콘텐츠로부터 음악적 정보를 분석하는 DSP(Digital Signal Processing) 기술로 최근 디지털 콘텐츠 시장의 확장과 더불어 연구가 활발히 진행되고 있다. 특히 웹이나 모바일에서는 이미 다양한 상용 어플리케이션이 적용되고 있는데 query-by-humming과 같은 음악 인식 어플리케이션이 대표적인 경우이다. 이 글에서는 onset 검출(onset detection)을 중심으로 음악적 리듬을 분석하는 알고리즘을 살펴보고 기본적인 조형원리에 따라 이를 시각화하는 어플리케이션의 예를 소개한다.

• 한국환경과학회지
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• 제11권4호
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• pp.289-295
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• 2002

We would like to investigate the strong wind phenomenon effecting to the onset of a sea breeze. It is general the fact that the onset time of a sea breeze is mainly affected according to the distance from the coastline but we find the reversal fact. The onset time at Suyoung is faster than that at Haeundae in spite of the observation site of Suyoung is 5 m and that of Haeundae is 1 km away from the coastline. This is the reason that the nighttime air is converged the lower area by surface cooling and then it is strongly drained onto the lowest area, Suyoung river until the sunrise. it is proved by observation data at Suyoung and Haeundae.