• Title/Summary/Keyword: olive

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Influence of Tyrosol on Cell Growth Inhibition of KB Human Oral Cancer Cells

  • Lee, Ue-Kyung;Kim, Su-Gwan;Go, Dae-San;Yu, Sun-Kyoung;Kim, Chun Sung;Kim, Jeongsun;Kim, Do Kyung
    • International Journal of Oral Biology
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    • v.41 no.4
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    • pp.175-181
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    • 2016
  • Tyrosol, a phenylethanoid and a derivative of phenethyl alcohol, possesses various biological properties, such as anti-oxidative and cardioprotective activity. Olive oil is the principal source of tyrosol in the human diet. However, so far the anti-cancer activity of tyrosol has not yet been well defined. This study therefore undertakes to examine the cytotoxic activity and the mechanism of cell death exhibited by tyrosol in KB human oral cancer cells. Treatment of KB cells with tyrosol induced the cell growth inhibition in a concentration- and a time-dependent manner. Furthermore, the treatment of tyrosol induced nuclear condensation and fragmentation of KB cells. Tyrosol also promoted proteolytic cleavage of procaspase-3, -7, -8 and -9, increasing the amounts of cleaved caspase-3, -7, -8 and -9. In addition, tyrosol increased the levels of cleaved PARP in KB cells. These results suggest that tyrosol induces the suppression of cell growth and cell apoptosis in KB human oral cancer cells, and is therefore a potential candidate for anti-cancer drug discovery.

Response of Oxygen Consumption and Gill Tissue of Fish Exposed to Red Tide Organism Cochlodinium polykrikoides (적조생물 Cochlodinium polykrikoides에 노출된 어류의 산소 소모량 및 조직 변화)

  • Shim, Jeong-Min;Lee, Chu;Lee, Yong-Hwa;Kim, Bong-Suck
    • Journal of Environmental Science International
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    • v.18 no.11
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    • pp.1283-1289
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    • 2009
  • Eco-physiological research and the control of Cochlodinium polykrikoides was carried out to elucidate eco-physiological characteristics of red tide organism through culture experiment depending on the condition of photon irradiance. Oxygen consumption of C. polykrikoides was high with a value of 1.12 mg/L/hr in the dark compared with that of 0.13 mg/L/hr at $100{\mu}mEm^{-2}s^{-1}$. DO values in a circular chamber with the lapse of time in seawater containing C. polykrikoides were declined in the dark period. DO values of seawater containing C. polykrikoides in the dark were declined from 7.01 mg/L to 2.65 mg/L in 30 cm depth and from 7.01 mg/L to 6.63 mg/L in 5 cm depth depending on the depth of circular culture vessel. Olive flounder, Paralichthys olivaceus and file fish, Stephanolepis cirrhifer exposed to Cochlodinium showed the separation of the lamella epithelium from gill filament, which disrupted the respiratory process at the gill level.

Emulsification Activity of Acinetobacter sp. 2-3A Isolated from Petroleum Oil-Contaminated Soil (유류오염 토양에서 분리한 Acinetobacter sp. 2-3A의 유화활성)

  • Lim, Ji-Hyun;Jeong, Seong-Yun
    • Journal of Environmental Science International
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    • v.18 no.11
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    • pp.1261-1270
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    • 2009
  • Fifty hydrocarbon-metabolizing microorganisms were isolated from soil samples polluted by the petroleum oils in Gamman-dong, Busan. Among them, strain 2-3A, showing strong emulsification activity, was selected by oil film-collapsing method. This bacterium was identified as Acinetobacter sp. and designated as Acinetobacter sp. 2-3A. The optimum temperature and pH on the growth of Acinetobacter sp. 2-3A were $25^{\circ}C$ and pH 7.0, respectively. The carbon and nitrogen sources for the most effective emulsification activity were 3.0% olive oil and 0.5% peptone, respectively. The 0.15% potassium phosphate was the most effective emulsification activity as a phosphate source. The optimum emulsification activity condition was $20^{\circ}C$, pH 7.0, and 2.0% NaCl. The optimum time for the best production of biosurfactant was 27 hrs. The emulsification stability was maintained at the temperature range from $4^{\circ}C$ to $100^{\circ}C$, pH range from 6.0 to 10.0, and NaCl range from 0% to 10%. For the oil resolvability of the biosurfactant, the residual oils were investigated by gas chromatography. As a result, it was verified that the biosurfactant decreased and decomposed crude oils from $_nC_{10}$ to $_nC_{32}$.

An analysis of botanical patterns식 religious symbol in clothing - focusing on comparison of Korea and Byzantine - (동서양 복식에 나타난 식물문양의 종교적 상징성 연구 -한국과 비잔틴의 비교를 중심으로-)

  • 이윤정
    • Journal of the Korea Fashion and Costume Design Association
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    • v.5 no.3
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    • pp.37-48
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    • 2003
  • 'Pattern' is of very unique nature in each and every country around the world, and its aesthetic feeling of 'pattern' has been handed down according to its nationality and cultural development process. That is, 'pattern' is ornament to symbolize each country's aesthetic standard or choice through some shape, reflecting social consciousness or religion philosophy. Mostly based upon literature survey and case study, this survey paper analytically compares oriental botanical pattern with occidental botanical figure, which has been influenced by Buddhism-Confucianism and Christian religion respectively. The results show that some patterns are commonly used in both area, while meaning differently in some cases: lotus (life), pomegranate (wealth and prosperity in orient, resurrection in occident), grape (fecundity in orient, wealth in occident), dangcho (fecundity in orient, victory in occident). And the other patterns look uniquely used either just in orient or only in occident. For instance, oriental area had its own patterns such as peony (meaning wealth and honour), peach (longevity), ume flower (happiness), orchid (fecundity); while occidental area used lily (purity), olive (peace), palm (victory), and so on. Interestingly, the botanical patterns were used as main patterns in orient whereas as minor in occident.

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Evaluation of the Quality of Canned Seafood with Added Spice-oil Extract

  • Yoon, Ho Dong;Shulgin, Yu.P.;Lazhentseva, L. Yu;Shulgina, L.V.;Xie, Chengliang;Mok, Jong Soo;Kim, Jeong Gyun
    • Fisheries and Aquatic Sciences
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    • v.18 no.1
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    • pp.7-11
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    • 2015
  • The influence of spice (cinnamon, allspice, black pepper)-oil extract on canned seafood quality was studied. During the processing of canned seafood, the substitution of spice-oil extract for vegetable oil (refined sunflower, corn, soybean and olive oil) resulted in a decrease in the heat resistance of spore microorganisms, making it possible to reduce the duration of sterilization for canned food to 5-10 min at $115^{\circ}C$. This reduction in the sterilization duration of canned seafood with spice-oil extract inhibited residual microflora in the product, thus reducing the deleterious effect of heating on the main food compounds while preserving protein digestibility.

Biological Estimation of Waste Products from Olive Flounder (Paralichthys olivaceus) Fed on Three Different Feed Types

  • Lee, Jin-Hwan;Jo, Jae-Yoon;Lee, Sang-Min;Cho, Sung-Hwoan;Hutabarat, Johannes;Spj, Nur Taufiq
    • Fisheries and Aquatic Sciences
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    • v.12 no.4
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    • pp.317-323
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    • 2009
  • Waste products were biologically estimated from juvenile flounder (Paralichthys olivaceus) on three diet types-raw fish-based moist pellets, moist pellets, and extruded pellets. Total solid and soluble wastes were estimated by determining nutrient digestibility and accumulation in juvenile flounders through growth trials. Total solid wastes produced were 20%-23% of the organic matter supplied. Soluble excretions ranged from 45% to 49%. Soluble nitrogenous excretions ranged from 36.4% to 46.2%. These results indicate that about 30.2%-35.9% of supplied feed is retained in the fishes' bodies while the remainder of feed is excreted into culture systems or the surrounding environment.

Quantitative Visualization of Supersonic Jet Flows (초음속 제트 유동의 정량적 가시화)

  • Lee, Jae Hyeok;Zhang, Guang;Kim, Heuy Dong
    • Journal of the Korean Society of Visualization
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    • v.15 no.1
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    • pp.53-63
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    • 2017
  • Sonic and supersonic jets include many complicated flow physics associated with shock waves, shear layers, vortices as well as strong interactions among them, and have a variety of engineering applications. Much has been learned from the previous researches on the sonic and supersonic jets but quantitative assessment of these jets is still uneasy due to the high velocity of flow, compressibility effects, and sometimes flow unsteadiness. In the present study, the sonic jets issuing from a convergent nozzle were measured by PIV and Schlieren optical techniques. Particle Image Velocimetry (PIV) with Olive oil particles of $1{\mu}m$ was employed to obtain the velocity field of the jets, and the black-white and color Schlieren images were obtained using Xe ramp. A color filter of Blue-Green-Red has been designed for the color Schlieren and obtained from an Ink jet printer. In experiments, two types of sonic nozzles were used at different operating pressure ratios(NPR). The obtained images clearly showed the major features of the jets such as Mach disk, barrel shock waves, jet boundaries, etc.

Oleuropein Induces Apoptosis Via the p53 Pathway in Breast Cancer Cells

  • Hassan, Zeinab Korany;Elamin, Maha Hussein;Omer, Sawsan Ali;Daghestani, Maha Hassan;Al-Olayan, Ebtesam Salah;Elobeid, Mai AbdelRahman;Virk, Promy
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6739-6742
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    • 2013
  • Background: Breast cancer is a major health problem worldwide. Olive oil induces apoptosis in some cancer cells due to phenolic compounds like oleuropein. Although oleuropein has anticancer activity, the underlying mechanisms of action remain unknown. The study aimed to assess the mechanism of oleuropin-induced breast cancer cell apoptosis. Materials and Methods: p53, Bcl-2 and Bax gene expression was evaluated by semi-quantitative reverse transcriptase polymerase chain reaction (RT-PCR) in luminal MCF-7 cells. Results: Oleuropein-induced apoptosis was accompanied by up-regulation of both p53 and Bax gene expression levels and down-regulation in Bcl2. Conclusions: Oleuropein induces apoptosis in breast tumour cells via a p53-dependent pathway mediated by Bax and Bcl2 genes. Therefore, oleuropein may have therapeutic potential in breast cancer patients by inducing apoptosis via activation of the p53 pathway.

Combined Genotoxic Effects of Aflatoxin B1, Ochratoxin A and Zearalenone in Rat Bone Marrow and Blood Leukocytes

  • Tigran, Harutyunyan;Anna, Karapetyan;Galina, Hovhannisyan;Rouben, Aroutiounian
    • Korean Journal of Environmental Biology
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    • v.31 no.3
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    • pp.189-191
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    • 2013
  • Mycotoxins such as aflatoxin B1 (AFB1), ochratoxin A (OTA) and zearalenone (ZEA) are widespread contaminants of food and feedstuffs. It is very likely, that humans and animals are always exposed to mixtures of mycotoxins rather than to individual compounds. Therefore, risk assessments should consider mixture toxicity data. In the present study the combination of AFB1, OTA and ZEA was tested for genotoxicity in rat bone marrow and blood leukocytes after 15, 30 and 60 days treatment. The level of DNA damage was determined by the comet assay. The tail intensity and Olive tail moment in leukocytes and bone marrow cells were significantly higher than in controls. At the same time, the level of DNA damage in bone marrow cells was higher than in leukocytes. The data suggests that prolonged exposure to mycotoxins combination through food consumption can induce DNA damage contributing to the harmful effects in vivo.

Effects of Cervi Pantotrichum on Hyperlipidemia in Rats (녹용(鹿茸)이 흰쥐의 고지혈증(高脂血症)에 미치는 영향에 관한 실험적 연구)

  • Park, Dong-Beum;Sung, Hyun-Jae;Kim, Ee-Hwa
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.20 no.2
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    • pp.372-376
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    • 2006
  • In order to study the effects of Cervi pantotrichum on hyperlipidemia, we divided the rats into three groups (normal group, control group & sample group) and perfomed the experimental research. Hyperlipidemia rat was induced by olive oil $1m{\ell}$(involved cholesterol 0.05g)/1200g for 10 days. The sample group was administerd the extract of Cervipantotrichum 10.8mg/200g for 5 days. and control group was administerd equal dose of saline. And then we measured the amount of serum total cholesterol, triglyceride, HDL-cholesterol, and phospholipid. Cervi pantotrichum showed decreasing effects on total cholesterol, LDL-cholesterol and phospholipid level, and increasing effects on HDL-cholesterol level in serum significantly. According to the above results, Cervi pantotrichum showed significant decreasing effects on hyperlipidemia, and it is considered that it is appropriate to apply for hyperlipidemia.