• Journal of Gastric Cancer
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• 제19권4호
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• pp.427-437
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• 2019

Purpose: We aimed to evaluate the clinical characteristics of microsatellite instability in early gastric cancer. Materials and Methods: The microsatellite instability status of resected early gastric tumors was evaluated using two mononucleotide repeat markers (BAT25 and BAT26) and three dinucleotide repeat markers (D5S346, D2S123, and D17S250). Tumors with instability in two or more markers were defined as microsatellite instability-high (MSI-H) and others were classified as microsatellite stable (MSS). Results: Overall, 1,156 tumors were included in the analysis, with 85 (7.4%) classified as MSI-H compared with MSS tumors. For MSI-H tumors, there was a significant correlation with the female sex, older age, tumor location in the lower gastric body, intestinal histology, lymphovascular invasion (LVI), and submucosal invasion (P<0.05). There was also a trend toward an association with lymph node (LN) metastasis (P=0.056). In mucosal gastric cancer, there was no significant difference in MSI status in tumors with LN metastasis or tumors with LVI. In submucosal gastric cancer, LVI was more frequently observed in MSI-H than in MSS tumors (38.9% vs. 25.0%, P=0.027), but there was no difference in the presence of LN metastases. The prognosis of MSI-H tumors was similar to that of MSS tumors (log-rank test, P=0.797, the hazard ratio for MSI-H was adjusted by age, sex, pT stage, and the number of metastatic LNs, 0.932; 95% confidence interval, 0.423-2.054; P=0.861). Conclusions: MSI status was not useful in predicting prognosis in early gastric cancer. However, the frequent presence of LVI in early MSI-H gastric cancer may help guide the appropriate treatment for patients, such as endoscopic treatment or limited LN surgical dissection.

• 대한지역사회영양학회지
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• 제13권3호
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• pp.374-385
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• 2008

A study has been performed to provide the basic information about the current dietary habits, health related behaviors, and body indices and to bring forward the importance of this information to the people's attention based upon the relation between employee's life patterns and health conditions in their daily lives. Three hundred and five department store workers were examined from August 2006 to September 2006. With the average BMI values $23.9{\pm}2.2$ for males and $20.0{\pm}1.9$ for females, both gender groups were in normal, but 62.2% of the males were overweight and 15.4% of the females were under-weight. Regarding dietary and health related factors on how they perceive themselves, as normal were 204 (66.9%) the most and bad and very bad were respectively 43 (14.1%) and 5 (1.6%). Half of the subjects (43.2%) perceived sleeping hours to be insufficient, and 64.4% of them need to exercise regularly. As problems related to eating habits, they reported irregular meal times, overeating, preference of hot and spicy food, skipping meal, unbalanced meals. Regarding weight control they have attempted were the most (73.0%), after weight reduction, 51.2% of the subjects had side effects, such as gastrointestinal troubles, anemia, dizziness, sense of fatigue, constipation, physiological disorder, and diarrhea, etc. In the food habit score, it was shown that overall average score of the subjects was $62.63{\pm}9.86$ which is lower than other studies. Female ($62.76{\pm}10.15$) had better score than male ($61.67{\pm}8.06$). While the item with the highest point was eat all three meals of the day, that was the lowest point, exercise every day. The food habit score of the younger group had lower than older group, and also they preferred sweet foods to other group. The results suggest that nutrition education for workers at specific working fields needs to be more focused on the improvement of dietary habits and health status of workers.

• 디자인학연구
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• 제19권2호
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• pp.293-300
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• 2006

미야자키 하야오가 지금까지 그려내 온 소녀는 자기주장과 독립심이 매우 강하며 단독으로 행동하며 동시에 호기심이 왕성하고 위험을 두려워하지 않는 젊은 여성 캐릭터가 많다. <하울의 움직이는 성>에서는 기존의 미야자키 하야오의 애니메이션에 등장하는 소녀상의 전형을 벗어난 새로운 여성상이 등장하고 있다. 소극적이며 자신감에 결여된 소피가 그러한데, 마법이라는 판타지를 통하여 하울이라는 분신과 다양한 연령의 여성으로 변신을 거듭한다. 소피의 신체로 표현되는 변화는 외부의 존재들과의 다양한 경험과 스스로의 모성의 획득을 의미한다. 그 중에서도 하울은 소피의 내부에 존재하는 다른 인격의 발현이며 상호약점의 보완과 조력으로 성숙된 인격에로의 성장과정을 함께 한다. 하울의 은신 장소이자 소피가 진입하게 되는 이중적 공간으로서의 성은 과거와 현재를 아우르며 그 외형을 바꾸어 나가며 있어야 할 곳을 찾지 못한 채 떠도는 존재들의 임시적인 공동체로서의 장소로도 작용한다. 종국에는 소피의 모성획득과 하울의 투쟁의 결과 성은 하늘을 나는 이상향으로서 정착한다. 작품 내에서 여러 가지 형태로 보여 지고 있는 성이미지는 연약하고 소극적인 존재의 현실 초월과 자유, 가능성이라는 의미를 가진다. 더불어 소피에 의한 모성의 획득도 중요한 의미를 가지는데, 이는 소피에게 결락되었던 모성을 획득하고 실천함으로서 하울에게도 휴식과 안정, 정화와 재생을 부여한다고 할 수 있다. 표면적으로는 애매하게 보이는 하울의 전투는 소피-미국 권 애니메이션에서 보여 지는 귀여운 남성성과는 전혀 다른-는 하울의 성숙된 자아로 나아가기 위한 적극적인 실행의 메타포인데, 자신들의 가장 어두운 부분과 조우하고 거기서 벗어난 후, 자폐와 두려움에서 벗어나 진정한 자아를 획득하게 된다.

• 한국산학기술학회논문지
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• 제18권2호
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• pp.660-671
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• 2017

본 연구는 우리나라 청소년들의 연령에 따른 이성교제 여부 변화와 이와 관련된 개인적 특성 및 가족과 학교의 특성을 살펴보는 것을 그 목적으로 하였다. 본 연구목적을 달성하기 위해 한국아동청소년 패널 원자료에서 중학교 1학년 코호트 자료 제 3차(2012년)~제 5차(2014년) 자료의 일부분을 추출하여 사용하였다. 본 연구에 포함된 대상자수는 총 1,961명이었다. 패널로짓분석을 실시한 결과, 연령이 증가함에 따라 청소년들은 이성교제를 할 가능성이 높았다. 또한 남자 청소년이 여자청소년에 비해, 자아존중감이 높은 청소년은 낮은 청소년에 비해 이성교제를 할 확률이 높았다. 그러나 부모의 애정적 양육행동, 이성형제 유무, 가구 소득과 같은 가족 특성은 연구 대상자의 이성교제 참여 확률에 유의한 영향을 미치지 않았다. 이와 달리 학교 특성은 이성교제 확률에 유의한 영향을 미쳤다. 남녀공학에 재학 중인 청소년이 그렇지 않은 청소년보다 이성교제를 할 확률이 높았다. 또한 학업과 학교 규칙 적응 정도는 이성교제 확률을 감소시켰으며, 이와 대조적으로 교우와 교사와의 긍정적인 관계는 그 확률을 증가시켰다. 이러한 연구결과를 바탕으로 청소년의 이성교제 활성화를 위한 제언과 본 연구의 한계점, 그리고 추후 연구에 대한 방향을 제시하였다.

• Journal of Preventive Medicine and Public Health
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• 제34권4호
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• pp.331-336
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• 2001

Objectives : To assess the prevalence of knee osteoarthritis through proper diagnosis in a rural community and to elucidate the relevant factors of this health problem in order to develop educational methods for the prevention of female knee osteoarthritis as well to provide basic data for prospective research. Methods : Over a period of three months starting from August, 2000, 432 women over the age of 40 and living in a rural area were selected by a multistage cluster sampling method in order to investigate the prevalence of knee osteoarthritis and the related factors. The study utilized interviews and radiological examination. The criteria of knee osteoarthritis used was the American College of Rheumatology classification criteria for osteoarthritis of the knee(1995). Results : The adjusted prevalence of knee osteoarthritis among the subjects was 55.0%, and multiple logistic regression analysis showed that the odds ratio(OR) of knee osteoarthritis among subjects 50-59 years of age and subjects older than 60 years of age as compared to subjects 40-49 years of age were 2.43(95% CI: 1.30-4.70) and 4.40(95% CI: 2.47-7.83), respectively. The OR of knee osteoarthritis among factory workers or farmers as compared to others was 1.79(95% CI: 1.03-3.12). The OR of knee osteoarthritis among subjects who had a family history and subjects who had knee injury or surgical history against those subjects had neither were 2.56(95% CI: 1.42-4.03) and 4.70(95% CI:1.45-15.19), respectively. The OR of knee osteoarthritis among smokers against non smokers was 0.47(95% CI: 0.22-0.97). Conclusions : Related factors of knee osteoarthritis included age, occupation, family history, smoking, knee injury and history of surgery In order to prevent knee osteoarthritis in high risked rural woman, education concerning self-care methods and safety guideline must be provided at the work place by the public and private health sectors. Additionally, these women should be continually encouraged to exercise, including jogging and swimming regularly.

• 한국콘텐츠학회논문지
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• 제17권5호
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• pp.357-365
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• 2017

본 연구는 미국, 중국, 일본 시청자들이 한국에서 방영된 대표적인 가족 드라마인 '부탁해요, 엄마'에 등장하는 주요 인물들의 성격, 태도 행동에 대해 어떻게 인식하는지, 인식을 근거로 인물의 '도덕성'을 어떻게 평가하는지 살펴보고 시청자들의 도덕성 평가가 드라마 흥미도와 질 평가에 관련이 있는지 분석하고자 한다. 분석결과 '남자 주인공 훈재'의 경우 3개국 시청자 모두 호의적으로 평가하였고, 이기적인 큰아들 형규는 3개국 시청자 모두 부정적으로 평가하여, 드라마의 선과 악을 판단하는 공통된 규범을 확인할 수 있었다. 그러나 진애, 영선, 산옥 등 부모와 자식의 역할에서 대립되는 양상을 보인 주요 여성 인물들에 대해서는 3개국 시청자 간에 평가가 엇갈렸다. 이는 부모와 자식과의 관계, 엄마와 여성의 역할에 대한 생각이 시청자의 문화적 배경에 따라 다르게 인식되기 때문이라고 해석할 수 있다. 또한 '주요 등장인물에 대한 도덕성 평가가 수용자가 느끼는 드라마 흥미도나 드라마의 질 평가에 영향을 미칠 것' 이라는 연구가설 역시 국가마다 다르게 검증되었는데 중국, 일본의 경우 지지되지 않았고 미국 시청자들에게만 지지되었다.

• Journal of Trauma and Injury
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• 제28권2호
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• pp.60-66
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• 2015

Purpose: Cultivator accidents are frequent and often lead to abdomino-perineal organ injury and, if severe, to death. This study presents the clinical characteristics, outcomes, and factors associated with mortality in patients who sustained an abdomino-perineal organ injury in cultivator accidents. Methods: We retrospectively analyzed the records of 53 patients who visited the emergency department of a tertiary hospital with abdomino-perineal organ injuries caused in cultivator accidents from April 2005 to March 2010. Results: All 53 patients had visited other medical institutions before visiting our hospital. Their mean age was $64.0{\pm}11.1$ (range, 20-80) years and 32 (60.4%) patients were 65 or older. The male-to-female ratio was 46:7. The chief complaint was abdominal pain (38 cases, 71.7%). The 53 patients included 41 cultivator operators (77.4%), 11 passengers (20.8%), and 1 passerby (1.9%). The causes of the injuries included a direct impact of the handlebar in 20 cases (37.7%), a rollover in 21 cases (39.6%), a fall in 10 cases (18.9%), and a wheel in two cases (3.8%). Several of the 53 patients had injuries to multiple abdomino-perineal organs, and the injured organs included the liver (23 cases, 26.4%), spleen (16 cases, 18.4%), pancreas (7 cases, 8.0%), small bowel (7 cases, 8.0%), mesentery (6 cases, 6.9%), adrenal gland (5 cases, 5.8%), and other organs. According to the abbreviated injury scale (AIS) dictionary, a thoracic injury was the most frequent co-injury (33 of 53 cases, 62.3%). Abdomino-perineal surgery was performed in 31 cases (58.8%) and angio-embolization was performed for six liver and two kidney injuries. Thirteen patients died (24.5%); all were males. The Injury Severity Scale (ISS) was lower in the survivors ($17.8{\pm}8.5$ vs. $27.0{\pm}16.0$; p=0.010). Conclusion: With the aging of agricultural workers, safety education programs should be implemented. Furthermore, the patient transfer system in agricultural areas must be improved.

• Journal of Trauma and Injury
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• 제32권3호
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• pp.143-149
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• 2019

Purpose: No previous study has assessed elderly pedestrian traffic accidents based on a nationwide database. This study aimed to help primary physicians who examine patients in emergency departments to determine and make prompt and accurate treatment decisions. Methods: This study used data from the Emergency Department-based Injury Indepth Surveillance from 2013 to 2017, managed by the Korea Centers for Disease Control and Prevention. Pedestrians aged ${\geq}65years$ were included, and using multivariate logistic regression multiple factors were analyzed to determine their relationship with injury severity. Results: Of 227,695 subjects, 6,498 were included, of whom 2,065 (31.8%) were severely injured. There were more female than male patients in all severity groups. Most accidents occurred in the afternoon and on general roads. In the multivariate analysis, the odds ratio (OR) of injury severity for male pedestrians was 1.165 (95% confidence interval: 1.034-1.313, p=0.012). Older age of patients and the use of ambulances were associated with greater injury severity. The accident time affected the degree of injury severity; i.e., compared to dawn, injury severity increased in the morning (OR: 1.246, p=0.047) and decreased at night (OR: 0.678, p<0.001). A significant difference was noted in the correlation between the type of vehicle causing the accident and the accident severity; i.e., motorcycle accidents had lower severity than bicycle accidents (OR: 0.582, p=0.047). Conclusions: Injury severity was correlated with sex, age, transportation to the ED, TA onset time, and type of vehicle. The study results suggest that injury severity may be positively reflected in initial assessments and overall integrated treatments by physicians and in the related policies.

• 한국ITS학회 논문지
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• 제18권3호
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• pp.1-13
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• 2019

이용객 감소, 고령화 등으로 어려움을 겪고 있는 농어촌버스의 대체수단으로 시범운영에 있는 수요응답형교통 콜버스에 대해 연구한다. 운영전 농어촌버스 대비 콜버스의 선호분석을 위해 로그선형모형을 구축하고 운영중의 콜버스 만족도를 조사하여 영향을 주는 요인을 순위회귀모형으로 실증 분석하였다. 연구결과로 문전서비스의 편리함으로 고령층과 이동수단에서 제약이 큰 것으로 예상되는 여성이 콜버스를 선호할 가능성이 높았다. 이동수단이 없거나 외출빈도가 낮은 경우에도 콜버스를 선호한다. 종속변수인 콜버스 만족도의 경중에 따른 순위분석에서 농어촌버스 선호자의 경우 연령, 가족수, 정류장거리, 외출횟수, 귀가시간에서 통계적 중요성을 보였고. 콜버스 선호자의 경우 성별, 이동수단, 정류장까지 거리, 버스만족도, 외출빈도, 출발시간, 귀가시간에서 통계적 중요성을 보였다. 전반적으로 운행전 콜버스에 긍정적 생각을 가진 대상자들이 콜버스 운행후에도 여전히 높은 만족도를 보였다.

• 한국환경과학회지
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• 제28권1호
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• pp.85-97
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• 2019

Meteorological factors and air pollutants are associated with respiratory diseases, and appropriate use of weather and air quality information is helpful in the management of patients with such diseases. This study was performed to investigate both the utilization of weather and air quality information by, and the needs of, patients with respiratory diseases. Questionnaires were administered to 112 patients with respiratory diseases, 60.7% of whom were female. The rates of bronchial asthma and chronic obstructive pulmonary disease among patients were 67.0% and 10.7%, respectively. The majority of subjects (90%) responded that prevention was important for respiratory disease management and indicated that they used weather and air quality information either every day or occasionally. However, respondents underestimated the importance of weather and air quality information for disease management and were unaware of some types of weather information. The subjects agreed that respiratory diseases were sensitive to weather and air quality. The most important weather-related factors were diurnal temperature range, minimum temperature, relative humidity, and wind, while those for air quality were particulate matter and Asian dust. Information was gleaned mainly from television programs in patients aged 60 years and older and from smartphone applications for those below 60 years of age. The subjects desired additional information on the management and prevention of respiratory diseases. This study identified problems regarding the utility of weather and air quality information currently available for patients with respiratory diseases, who indicated that they desired disease-related information, including information in the form of action plans, rather than simple health- and air quality-related information. This study highlights the necessity for notification services that can be used to easily obtain information, specifically regarding disease management.