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Studies on the immunization against field strain after live Newcastle disease virus vaccination (뉴캣슬병 생독백신 접종 후 야외 분리 바이러스에 대한 면역성 조사)

  • 김순태;박인화;김성국;김영환;조광현;손재권
    • Korean Journal of Veterinary Service
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    • v.24 no.2
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    • pp.147-159
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    • 2001
  • This Study was conducted to determine vaccination programs for the control of Newcastle Disease(ND) in chickens and investigate protective effect against Newcastle disease virus (NDV) after live ND vaccination. Maternal HI antibody titer level of chickens according to day(age) 1, 7, 14, 21, 28 and 35 were decreased gradually as 7.10$\pm$0.74, 6.57$\pm$0.74, 3.71$\pm$1.25, 2.20$\pm$1.03, 1.20$\pm$1.23 and 0.50$\pm$0.71. As a result of HI test and ELISA, both chickens vaccinated with VG/GA strain live vaccine at 1-day-old and chickens not vaccinated do not have antibody titer for protection against NDV at 14-day-old. Except for LaSota strain vaccine, in case of vaccination with VG/GA spray and VG/GA, B1 and LaSota strain drinking water at 14-day-old, the protective effect was 100% in chickens inoculated NDV($10^{7.2}$ $EID_{50}$/50${\mu}\ell$, eye drop) at 21-day-old, but not 10~50% at 28-day-old. These data suggest that live NDV vaccination should be given at 10-day-old 20-25day-old for protect against NDV at periodic outbreaks of ND caused by velogenic viscerotropic NDV in the environment of a farm.

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Effect of Extraction Ethanol Concentration on Antioxidant and Anti-Inflammatory Activity of 30-Year-Old and 120-Year-Old Dangyuja (Citrus maxima (Burm.) Merr.)

  • Lee, Sung-Gyu;Lee, Dongsup;Kang, Hyun
    • Biomedical Science Letters
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    • v.26 no.2
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    • pp.109-113
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    • 2020
  • Dangyuja (Citrus maxima (Burm.) Merr.) is a native fruit of great economic importance in Jeju island in Korea. To provide experimental evidence for the antioxidant and anti-inflammation properties on extraction ethanol concentration of Dangyuja, 2 cultivars, including 30-year-old and 120-year-old were evaluated. 30-year-old Dangyuja 50%, 70% ethanol extracts had the highest polyphenol and flavonoid content, and the strongest 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activity. To investigate the anti-inflammatory activity of Dangyuja ethanol extracts, we used BV-2 microglia cells and induced inflammation using lipopolysaccharide (LPS). Then, we measured levels of inflammatory mediators as nitric oxide (NO). Among the 6 extracts, 30-year-old Dangyuja 50% ethanol extracts show the highest anti-inflammatory activity. The results suggest that 30-year-old Dangyuja 50% ethanol extracts provides significant health benefits and may be used for developing new functional materials.

일측성선조체의 6-OHDA손상 후 도파민효능약물 투여로 발현된 회전운동의 특성

  • 이순철;문민선
    • Journal of Ginseng Research
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    • v.21 no.1
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    • pp.61-67
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    • 1997
  • The present study examined the characteristics of behavior Induced by dopamine agonists following treatment with 6-hydroxydopamine(6-OHDA) unilaterally into left striatum in rats. 6-OHDA was administered at doses of 8,16 and 24 $\mu\textrm{g}$/$\mu\textrm{l}$(in 0.1% ascorbic acid) into dopaminergic neurons in left striatum of 7 weeks old rat under anesthetic. Locomotor activity was significantly decreased at 1 week following 6-OHDA-administration in 7 weeks old rats. The contralateral circling behavior was induced by apomorphine(5 mg/kg, i.v.) after 1 week following 6-OHDA(24$\mu\textrm{g}$/$\mu\textrm{l}$) treatment, and was further increased by repeated administration of apomorphine at 2, 3 and 4 weeks. The contralateral circling behavior was also induced by lisuride and 1-dopa in a dose dependent manner, but not by SK & F 82526 in 7 weeks old rats treated with 6-OHDA. The contralateral circling behavior was significantly higher in 21 weeks old rats but significantly lower In 35 weeks old rats when compared with 7 weeks old rats. The contralateral circling behavior induced by apomorphlne did not differ significantly in 7 and 35 weeks old male and female rats. These results suggest that 6-OHDA treatment into left striatum causes remarkable destrurtion of intrastriatal dopaminergic netcons leading to dopaminergic receptor supersensitivity. Thus, the contralateral circling behavior in duces by apomorphine may be used as indicator for neurodegenerative diseases.

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Survey of Shoes Wearing Reality and Old Males Foot Types

  • Shim, Boo-Ja;Yoo, Hyun
    • Journal of Fashion Business
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    • v.11 no.3
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    • pp.1-14
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    • 2007
  • This research to reveal the foot types of old males consisted of two parts. First, a questionnaire was given for 180 old men in their 60s and above who live in Busan. Second, based on this survey on the reality of shoes wearing, direct and indirect measurement were held for 200 old gentlemen. The findings are as follows: 1. Survey Results of Shoes Wearing Reality In the investigation into the reality of shoes possession and wearing, most of old males favored active casual shoes with comfortable materials (40.8%). Hardened skin (23.6%) was the greatest in foot deformation and side effects resulting from shoes wearing, while the big toe (20.1%) was most uncomfortable. The greatest requirement for comfortable shoes was shoes making feet comfortable with a good sense of wear (41.0%), followed by shoes with the soft sole to absorb shock (31.7%), shoes with diverse sizes according to shoes width (13.7%), and shoes made of soft materials in consideration of various foot shapes. 2. Results of Foot Measurement Experiments Busan's males in their 60s and above were 166.31cm (Height), 63.51kg (weight), 23.94cm (foot length), 9.75cm (foot width), and 24.26cm (instep girth). The big toe angle of old males was $11.22^{\circ}$ and the little toe angle $14.70^{\circ}$. Four foot types were classified: 1 (long big foot), 2 (small inside-developed foot), 3 (toe-tip-gathered foot), and 4 (thin flat foot).

How Do Korean Elderly Women Adapt to Old Age?:Themes and Sources of Meaning in Their Later Lives from Life Stories (한국여성노인들의 노년에 적응과 노년기 삶의 모습에 대한 질적 연구)

  • 강유진
    • Journal of the Korean Home Economics Association
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    • v.41 no.3
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    • pp.131-146
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    • 2003
  • The purpose of this study is to explore what makes the elderly women resilient in old age and how they reconstruct their later lives. This study used life histories extracted from tape-recorded interviews of 13 elderly women and analyzed key issues focused on how to adapt in old age. Main results are following: First, emerging themes to maintain life satisfaction in old age are related to both informants' inner and outer life worlds; subjective reinterpretation of life, feeling rich, family, social activities, overcoming social stigma. With supporting and supplementing one another, these five dimensions are important contributors to better later life. Second, where my informants search for meaning of life in old age is the critical clue of understanding the later life styles. Some of them are still searching meaning of life in roles as a ‘mother’, while others are finding their sense of worth outside the family or in themselves. These results show that the elderly are interacting with themselves and their surroundings in adapting to old age and different tie styles according to different sources of life satisfaction manifest the changes among the elderly and Korean society.

Increased Rate of Palmitate Oxidation in Adults Female: Comparison with Peri-pubertal Young Female Rats

  • Lee, Se-Young;Kim, Jong-Yeon;Kim, Yong-Woon;Park, So-Young
    • The Korean Journal of Physiology and Pharmacology
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    • v.10 no.5
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    • pp.283-287
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    • 2006
  • Although estrogen is known to playa role in fatty acid metabolism, it remains unclear whether fatty acid oxidation in mature female rats differs from fatty acid oxidation in peri-pubertal young rats. In this study, we measured fatty acid metabolism in the skeletal muscles and livers of 5 and 50 weeks old male and female rats. The rate of palmitate oxidation in the liver and gastrocnemius red in the 50-week-old female rats were elevated as compared to the 5-week-old females, whereas there were no differences in the male rats. The rate of palmitate oxidation in the gastrocnemius red was correlated inversely with intra-abdominal fat mass in the 5-week-old male and female rats, whereas the palmitate oxidation rate was positively correlated with fat mass in the liver and gastrocnemius red in the 50-week-old rats. HOMA-IR and plasma insulin levels were positively correlated with intra-abdominal fat mass in the pooled 50-week-old male and female rats, but this correlation was not apparent in 5-week-old rats. In summary, the rate of fatty acid oxidation measured in the middle-aged adult female rats was significantly higher than those measured in the peri-pubertal young female rats. This difference may be attributed to the influence of ovarian hormones.

Conservation and Regeneration of Old Residential Block in Downtown - Focused on the 39~134 Namju-Dong Outside South Gate of Cheongju, Korea - (도심 옛 주거지의 보존 및 재생계획 - 청주 남문 밖 남주동 39~134번지의 블록을 중심으로 -)

  • Park, Sang Ah;Lee, Jun Beom;Kim, Tai Young
    • Journal of the Korean Institute of Rural Architecture
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    • v.26 no.3
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    • pp.19-28
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    • 2024
  • This study aims to find the conservation and regeneration plan in terms of preserving and utilizing old wooden houses, regenerating existing buildings, and developing idle land for old dwellings located outside the southern gate of Cheongju, Korea. In the preservation and utilization of old houses, three places in the block where wooden houses clustered are created as conservation houses, and are conversed as cafes, workspaces, and homestays along with the preservation of individual houses. In the regeneration of existing buildings, the street landscape was improved through extension and renovation, new construction after demolition, and exterior renovation for one or two-story buildings facing the roadside. In the development of idle land, it reflects the layout method and open yard space corresponding to the path and orientation of the old house, and the mass was varied and segmented to resolve the medium scale. Accordingly, considering the context, landscape, and environmental aspects of the historical downtown, the development of old dwellings in downtown should shift from a uniform high-rise apartment project-oriented approach to a gradual and continuous regeneration direction.

Factors Related to Health Promoting Behaviors of Young-Old and Old-Old Elderly in Rural Areas (농촌지역 전기노인과 후기노인의 건강증진행위 관련요인)

  • Lee, Myung-Suk;Lim, Hyun-Ja
    • Journal of agricultural medicine and community health
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    • v.35 no.4
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    • pp.370-382
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    • 2010
  • Objectives: The purpose of this study was to investigate the level of health promoting behaviors and the significant factors in rural elderly(young-old vs old-old). Methods: The data was collected using structured questionnaires from June 22th to Sep. 18th, 2009. A total of 556 elderly aged 65 years or over were selected from 14 rural districts in C province, South Korea. Age was divided into two groups as below 65-74 and 75 or older. A structured questionnaire was used to obtain information on the demographic characteristics, their perceived health status, the difficulty of activities of daily living, quality of life, self-efficacy and health promoting behaviors. The health promoting behaviors included nutrition, stress management, interpersonal support, exercise, health responsibility and self-actualization. The scores for health promoting behaviors were used mean and standard deviation. The data was analyzed using SPSS Win 12.0. Results: Of the 556 subjects, we found that the young-old(65-74 aged) were 359 and the old-old elderly(over 75 aged) were 197. We found that the level of health promoting behavior was higher for young-old ($2.75{\pm}0.374$) compared to old-old elderly people ($2.67{\pm}0.399$). In multiple linear regression, quality of life, self-efficacy, living with spouse, and number of generation living together for the young-old, and quality of life for old-old elderly were significantly associated with health promoting behaviors. Conclusions: The study findings indicate that there are age differences in associated factor of health promoting behaviors. Therefore our findings may provide useful assistance in developing effective intervention programs to improve health promoting behavior of the elderly in rural areas according to their age differences.

Leisure Performance and Leisure Satisfaction by Preference Leisure Performance in the Elderly: Comparison between Young-old and Old-old (노년기 선호여가 수행여부에 따른 여가수행도 및 여가만족도의 차이분석: 전기노인과 후기노인의 비교)

  • Woo, Ye-Shin;Park, Da-Sol;Shin, Ga-In;Park, Hae-Yeon
    • 한국노년학
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    • v.39 no.2
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    • pp.199-211
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    • 2019
  • The purpose of this study is to analyze leisure satisfaction and leisure performance according to whether elderly people are performing their preferred leisure activities. For the analysis, we used sample from the 6th (2015) panal data as Korean Retirement and Income Study(KReIS). The results of this study were as follows. First, the total data of 4,197 elderly (2,212 young-old and 1,985 old-old) were analyzed. As a result, weekday and weekend leisure time of the old-old (7.64 hours / 7.81 hours) than the young-old (6.83 hour / 7.39 hour) was increased and resting activites (over 70% of watching TV and listening to the radio) accounted for more than 80% of the both elderly leisure activities. Leisure performance were higher in old-old who did not perform preferred leisure activities during weekdays. Leisure performance on weekends was higher in old-old regardless of whether they had preferred leisure time. Average of leisure performance was high in both groups and they responded leisure satisfaction was moderate. In the case of need for leisure change, young-old was higher than oid-old regardless of preference leisure performance and day of the week. However, the responses of the both groups are closed to those that do not want to change. Based on the results of this study, it should be practiced such as develomenting program and introduction of health management system considering leisure constraints to improve leisure satisfaction and continuance of leisure activities for young-old and old-old. We also emphasize the need for a systematic survey scale that takes into account the qualitative aspects of leisure activities as well as the subjective factors influencing leisure participation.

Changes of Pharmacological Components and Growth Characteristics According to Cultivation Years of Artemisia capillaris Thunb (사철쑥의 재배년수에 따른 생육과 약리성분 변화)

  • Choi, So-Ra;You, Dong-Hyun;Ju, In-Ok;Jang, Ik;Kim, Jong-Yeob;Park, Chun-Bong;Ryu, Jeong
    • Korean Journal of Medicinal Crop Science
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    • v.16 no.1
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    • pp.57-61
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    • 2008
  • This experiment was carried out to search for changes of growth and pharmacological component contents by cultivation years in Artemisia capillaris. Percentage of ovenwintering in 1-year old was high as 95.3% but that in 2-years old was very low as 64.2%. Plant height was the highest in 2-years old among the treatments. By the way, number of stems and branches were shown wide difference by cultivation years, so those were the best in 3-years old. It was thought that 3-years old plants dispersed and used their nutrients by increasing branches. Fresh weight was the highest as 200.0 g in 3-years old, whereas weight of capitulum included scoparone, effective component, was the highest as 109.6 g in 2-years old and low as 96.4 g in 3-years old. In general components, crude protein and ash were more included in 1-year old and crude lipid and fiber were more included in 2 and 3-years old. Especially, content of crude fiber in stem was the highest in 3-years old. Pharmacological components were the most existed in capitulum of 2-years old, so contents of scoparone and capillarisin were 6.5 mg/g DW, 1.65 mg/g DW, respectively.