• Medical Lasers
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• v.9 no.1
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• pp.76-78
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• 2020

Verruca plana is a cutaneous infection caused by the human papilloma virus. Although various treatment methods are currently available, most have limitations due to the risk of complications such as hyperpigmentation, edema, and scarring. Moreover, as the infection tends to spread easily, new verrucae can potentially develop, and treatment procedure times tend to be lengthy. Thus, novel treatment methods are required. The 2790-nm wavelength erbium:yttrium-scandium-gallium-garnet (Er:YSGG) laser is a superficial resurfacing laser. Here, we present a case of a 25-year-old woman with multiple verrucae treated using a 2790-nm Er:YSGG laser. Compared to traditional methods, this novel laser is convenient, produces better cosmetic outcomes, and is less time-consuming; it is therefore suitable for the treatment of facial verruca plana.

• Journal of Genetic Medicine
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• v.18 no.1
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• pp.44-47
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• 2021

Cerebral creatine deficiency syndrome (CCDS) is a disorder where a defect is present in transport of creatine in the brain. Creatine plays an essential role in the energy metabolism of the brain. This is a genetic disorder, autosomal recessive or X linked, characterized by intellectual disability, speech and language delay, epilepsy, hypotonia, etc. Until recently very few number of cases have been reported. Here we report a case of 1.5-year-old boy who had epilepsy (epileptic spasm and generalized tonic clonic seizure), intellectual disability, microcephaly, hypotonia and speech delay. His magnetic resonance imaging of brain showed cortical atrophy and electroencephalography showed burst suppression pattern. The diagnosis was confirmed by clinical exome sequencing which showed novel mutation of SLC6A8+ in exon 9, suggestive of X linked recessive CCDS. The patient was then treated with glycine, L-arginine and creatine monohydrate with multiple antiepileptic drugs.

• Journal of Genetic Medicine
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• v.19 no.1
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• pp.38-41
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• 2022

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a single-gene disease caused by mutations in the neurogenic locus notch homolog protein 3 (NOTCH3) gene. The spectrum of clinical manifestations is broad, ranging from asymptomatic to typical ischemic stroke, and mainly depends on the location of the mutations. We describe the case of a 76-year-old female without apparent neurological deficits. However, brain magnetic resonance imaging revealed confluent lesions in the white matter. Direct sequencing of the NOTCH3 gene revealed a novel pathogenic mutation, c.811T>A, which results in a mild phenotype. Therefore, this report will expand the current knowledge in regards to the mutations that can cause CADASIL.

• Korean Journal of Radiology
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• v.21 no.4
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• pp.501-504
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• 2020

From December 2019, Coronavirus disease 2019 (COVID-19) pneumonia (formerly known as the 2019 novel Coronavirus [2019-nCoV]) broke out in Wuhan, China. In this study, we present serial CT findings in a 40-year-old female patient with COVID-19 pneumonia who presented with the symptoms of fever, chest tightness, and fatigue. She was diagnosed with COVID-19 infection confirmed by real-time reverse-transcriptase-polymerase chain reaction. CT showed rapidly progressing peripheral consolidations and ground-glass opacities in both lungs. After treatment, the lesions were shown to be almost absorbed leaving the fibrous lesions.

• (The)Study of the Eastern Classic
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• no.37
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• pp.161-188
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• 2009

How did Japanese who surrender to Joseon reflect in old proses / Seo, Shin-hye This paper is focus on Japanese who surrender to Joseon. I researched how were these people to live through old novel, old tale and old biography. And I researched how these works reflected these people. Usually Japanese who surrender to Joseon were butchers. They were loyal to Joseon and their higher officer to a fare-thee-well. In old proses, writters compared these surrender with Joseon's general. People expect the general loyalty, but he didn't. Because of surrender's loyalty, Joseon's general was seen as an abject coward. This form came out in common in the biography of Gim Yeongcheol, the biography of Gang Hongrip and the biography of Gim Chungseon. But this fact was biased. All of Japanese surrender was not loyal, and they liked fighting in the battle. The singularity of the biography of the butcher who is Buddhist monk attracted our attention. In this work, we can see the surrender's mental conflict. We can realized the people is equal with Joseon's people.

• International Journal of Internet, Broadcasting and Communication
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• v.15 no.4
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• pp.215-222
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• 2023

In this paper, we examine the roles, mutual relationships, and guidelines for a healthy life as exemplified by the characters Santiago and Manolin in Ernest Hemingway's novel "The Old Man and the Sea" and use this content to compare the happy home life of elderly couples in Korea. Through a metaphorical exploration of the lives of elderly husbands and wives in Korean society, the study examines their significance as the core of the family, particularly during their senior years. Ernest Hemingway's "The Old Man and the Sea" portrays Santiago as a unique embodiment of virtue and humanity. As an elderly male fisherman, he symbolizes a profound connection with the sea, as well as qualities such as courage, patience, and unwavering passion. His story underscores the importance of pursuing new goals and maintaining hope even in old age. The relationship between Santiago and Manolin provides insights into the dynamics of elderly husbands and wives in their domestic lives. Manolin's unwavering support for Santiago and his understanding of Santiago's dreams exemplify the significance of mutual support and the establishment of common goals for elderly couples. These characters serve as exemplary models for understanding and supporting one another within a family setting. Within the context of family life, applying these exemplary models and relationship dynamics fosters mutual respect, collaboration, emotional expression, and effective communication. Supporting each other and working towards common goals can enhance the family atmosphere, resolve conflicts, and enrich domestic life. Furthermore, when elderly couples share common goals and enjoy activities together, they strengthen their bond and create a more fulfilling family life. These shared activities deepen the affection between elderly husbands and wives and contribute to a thriving household. Through the characters of Santiago and Manolin in "The Old Man and the Sea," we present in this study a deeper understanding of the values and roles within the domestic lives and affection of elderly husbands and wives. Mutual respect, collaboration, emotional expression, communication, mutual support, common goals, hope, and shared domestic activities all play pivotal roles in maintaining a healthy family life and establishing happiness and well-being within the family. We expect this study to offer valuable insights into the fields of family studies, elderly welfare, and sociology.

• Clinical and Experimental Pediatrics
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• v.59 no.12
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• pp.490-493
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• 2016

Electronic cigarettes are novel tobacco products that are frequently used these days. The cartridge contains liquid nicotine and accidental poisoning, even with a small oral dose, endangers children. We present here a mortality case of a 15-month-old child who ingested liquid nicotine mistaking it for cold medicine. When the emergency medical technicians arrived, she was found to have pulseless electrical activity. Spontaneous circulation was restored after approximately 40 minutes of cardiopulmonary resuscitation. The cotinine level in her urine was 1,716 ng/mL. Despite intensive supportive care, severe anoxic brain injury was found on computed tomography and the child ultimately died. This fatality highlights the need for public health efforts to minimize such accidents.

• Knowledge Management Research
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• v.10 no.1
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• pp.53-70
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• 2009

This study empirically explored what promotes exploration, through a case analysis of a Korean SME (small and medium sized enterprise), based on the research framework which focuses on the identification and the selection of exploratory NPD (new product development) alternatives, and the accumulation of novel capabilities in new technology domains. The learning process of the exploratory NPD project described is as follows. The identification barrier of exploratory NPD project is relatively low. Constructive crisis is germane to selecting exploratory NPD alternatives and to enduring the long payback period. New separated R&D unit is likely to implement the exploratory NPD project. The length of the gestation period of the exploratory NPD project is related with the level of the conflict between old members and new members. This study identified several antecedents of the exploratory NPD project. Prior success promotes the identification process of the exploratory NPD projects. Constructive crisis is related with CEO's personal characteristics such as future oriented and proactive personality. The proactive involvement and persuasion of CEO are germane to reducing the conflict between old and new members and to the success of the exploratory NPD project. Based on the results, this study discusses several implications and future research directions.

• Archives of Plastic Surgery
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• v.41 no.1
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• pp.77-80
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• 2014

We report a case of sternal reconstruction using bilateral sternal bar turnover flaps in a 4-year-old boy with an inferior sternal cleft, as part of Cantrell's pentad. When the patient was 10 months old, he underwent sternal reconstruction using a resorbable poly-L-lactic-polyglycolic acid plate in the first stage when there was insufficient autogenous tissue to provide a reliable reconstruction. Bilateral sternal bar turnover was performed in the second stage at 4 years of age. This operative technique is described in this report. This novel technique provides a robust, dynamic, and reliable reconstruction for inferior sternal defects.

• Pediatric Infection and Vaccine
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• v.29 no.2
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• pp.61-69
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• 2022

Coronavirus disease 2019 (COVID-19) has been a global pandemic for over 2 years. During the Omicron (B.1.1.529) variant-predominant period in South Korea, confirmed cases among children and adolescents surged. This review found that, although younger children may be less susceptible to COVID-19 than adolescents, more research is needed on the role of children and adolescents in the disease's spread. Detailed epidemiological information about the transmissibility of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strain in children and adolescents is currently scarce, and more research is needed on the role of children and adolescents in disease's spread. There may be a difference in the proportion of cases with severe disease requiring hospitalization depending on the dominant mutant strain; however, COVID-19 generally presents with a mild-to-moderate course in children aged 5-11 years old.