• Korea-Australia Rheology Journal
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• 제18권4호
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• pp.183-189
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• 2006

High internal phase emulsions are highly concentrated emulsion systems consisting of a large volume of dispersed phase above 0.74. The rheological properties of high internal phase water-in-oil emulsions were measured conducting steady shear, oscillatory shear and creep/recovery experiments. It was found that the yield stress is inversely proportional to the drop size with the exponent of values between 1 and 2. Since the oil phase contains monomeric species, microcellular foams can easily be prepared from high internal phase emulsions. In this study, the microcellular foams combining a couple of thickeners into the conventional formulation of styrene and water system were investigated to understand the effect of viscosity ratio on cell size. Cell size variation on thickener concentration could be explained by a dimensional analysis between the capillary number and the viscosity ratio. Compression properties of foam are important end use properties in many practical applications. Crush strength and Young's modulus of microcellular foams polymerized from high internal phase emulsions were measured and compared from compression tests. Of the foams tested in this study, the foam prepared from the organoclay having reactive group as an oil phase thickener showed outstanding compression properties.

• Journal of Pharmaceutical Investigation
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• 제36권4호
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• pp.245-251
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• 2006

The novel microsphere blending and multiple emulsion method by single process was tried to prepare sustained release microspheres which release a physiologically active substance for long periods of time. A drug was separately dissolved in each of two or more oils containing biodegradable polymers to give the primary oil phases. The primary oil phases were dispersed in single aqueous phase in succession. From the drug-dispersed solution, the organic solvent was removed to produce microspheres. The accelerated drug release from the microsphere formulation prepared by single process through the multiple emulsion method was very similar to a physical blending of separately prepared microspheres using the same polymers. But long term release was not same. In this study, leuprorelin acetate loaded poly(lactide-co-glycolide) microsphere formulation for one-month delivery was developed by the multi-emulsion method followed by solvent extraction/evaporation method.

• 한국식품영양학회지
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• 제27권4호
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• pp.706-715
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• 2014

The purpose of this study was to determine the optimal mixing ratio of Alaska Pollack (Theragra chalcogramma) and olive oil in the preparation of sausage. The experiment was designed according to the central composite design for estimating the response surface, which demonstrated 10 experimental points including 2 replicates for Alaska Pollack and olive oil. The physical, mechanical and sensory properties of test materials were measured. A canonical form and perturbation plot showed the influence of each ingredient on the final product mixture. Measurement results of the physical and mechanical properties showed a significant increase or decrease in the following properties: dough sweetness (p<0.05); sausage L (p<0.05), a (p<0.001), and b (p<0.01); hardness (p<0.01), chewiness (p<0.05), and gumminess (p<0.01). Also, the sensory measurements showed a significant improvement in color (p<0.05), flavor (p<0.01), taste (p<0.001), tenderness (p<0.05), chewiness (p<0.01), mositness (p<0.05), and overall quality (p<0.01). As a result, the optimum formulation by numerical and graphical methods was calculated as Alaska Pollack 35.74 g and olive oil 7 g.

• 한국식품영양학회지
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• 제27권2호
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• pp.256-266
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• 2014

The purpose of this study was to determine the optimal mixing conditions of soybean oil and bread crumbs mixture for pork patty. The experiment was designed according to the central composite design of response surface methodology. There were ten experimental points, including two replicates for soybean oil and bread crumbs. The physicochemical and mechanical analyses of each sample, including pH, cooking loss, thickness increase, moisture content, lightness, hardness, adhesiveness, springiness, chewiness, and gumminess showed significant differences (p<0.05). The results of sensory evaluation showed significant differences in tenderness, juiciness, and overall quality (p<0.05). The optimum formulation calculated by numerical and graphical method was 13.61 g of soybean oil and 6.35 g of bread crumbs. The results obtained in this study will be useful to the meat industry, which tends to decrease the saturated fatty acid content with a concomitant enrichment in the unsaturated fatty acids content.

• Fisheries and Aquatic Sciences
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• 제1권1호
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• pp.30-34
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• 1998

Rotifer culture fed on five types of artificial microparticle diets were evaluated to substitute the natural diets such as Chlorella or w-yeast. These microparticle diets including solidified blood using squid oil (SBSO), solidified blood using soybean oil (SBSB), nylon protein walled particle (NPW) simple coacervation oil capsule (SCO), complex coacervation oil capsule(CCO), were tested for the evaluation of feeding efficiency. The prepared micro particle diets had diameters ranging from 3 to 30 Jim. Rotifer culturing experiments were carried out in 3-liter beakers for 13-16 days. The initial inoculum density of rotifers was 10 ind./ml. The rotifers fed on Chlorella or $\omega-yeast$ showed maximal densities of 2,000 ind./ml in 9 days or 500 ind./ml in 7 days, respectively. Those fed on SBSO, SBSB or NPW showed maximal densities of 1568 ind./ml, 586 ind./ml or 503 ind./ml, respectively and the reproductive rates for those diets were equivalent to or better than w-yeast. However, the coacervated oil capsule showed lower maximal densities of 400 ind./ml for SCO and less than 100 ind./ml for CCO due to the unbalanced diet formulation and indigestibility.

• Journal of Pharmaceutical Investigation
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• 제30권4호
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• pp.259-266
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• 2000

Vitamin A palmitate, an oily drug which has low chemical stability and is poorly absorbed in the intestine, was formulated into a novel powdered dosage form. This is designated as a redispersible dry emulsion by freeze-drying technique. Before preparing a dry emulsion, vitamin A palmitate oil in solid in water (O/S/W) emulsion with soybean oil and coconut oil using Aerosil 200 as an emulsion stabilizer and polyoxyethylene-polyoxypropylene-blockcopolymer (Pluronic F68) as a surfactant was prepared. The resultants of the stability tests indicated that vitamin A palmitate O/S/W emulsion was improved on increasing the oil content of the formulation. The resultant dry emulsion particles have a good stabilities and free flow properties and readily released the oily droplets to form stable emulsions on rehydration. The drug releasing property from the resultant dry emulsion particles was dependent on factors such as amount of oily carrier(soybean oil) and surfactant(Pluronic F68) formulated. Above 80% of vitamin A palmitate content was released from the dry emulsion for 1 hour. It was deduced that vitamin A palmitate dry emulsion was definitely suitable for oral administration, since small droplets of vitamine A palmitate from the dry emulsion may alter the drug absorption profile resulting in bioavailability enhancement.

• 공업화학
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• 제30권4호
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• pp.415-420
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• 2019

비이온 계면활성제와 유화안정제가 O/W 유화 제형에 미치는 영향을 살펴보기 위하여 비이온 계면활성제와 유화안정제 종류를 달리한 여러 제형을 만들어 이들의 유변학적 특성을 비교하였다. 친수성 비이온 계면활성제는 polysorbate 60 (Tween 60), PEG-60 hydrogenated castor oil (HCO 60), octyldodeceth-16 (OD 16), ceteareth-6 olivate (Olivem 800) 등을 사용하였고, 유화안정제로는 cetyl alcohol, glyceryl monostearate, stearic acid 등을 각각 사용하였다. Octyldodeceth-16을 사용한 유화 제형에서만 상분리가 일어나고 나머지 제형은 모두 안정한 상을 유지하였다. 계면활성제 ceteareth-6 olivate와 유화안정제 cetyl alcohol을 혼합 사용한 제형의 점도, 경도, 크림성 등이 가장 높게 나타나고 유화된 입자 사이즈도 가장 큰 값으로 측정되었다. 이와 같은 결과는 유화 제형에 액정이 많이 생성되면서 네트워크 구조의 텍스처가 형성되었기 때문이다. 이 제형에서는 탄성적 특성이 크게 나타나고 힘이 가해지는 이력에 따라 점도 값이 달라지는 씩소트로픽 현상이 나타났다.

• 한국환경농학회지
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• 제29권3호
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• pp.239-246
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• 2010

Aphids are one of the major pests in agricultural crops. A number of synthetic pesticides have been used for control of aphids in agriculture, but increasing public concerns over their adverse effects on the environment have required more environmentally-friendly methods for pest management. In this study, we examined plant oil formulations for the control of green peach aphid (Myzus persicae). Oil formulations were prepared by hydrolyzing the plant oils in ethanolic KOH solution and diluted at the rate of 1:500 for aphid control. The oil formulations showed aphid mortalities ranging from 24.44 to 43.33% in vitro. Significantly increased aphid mortalities were observed by the treatment of oil formulations combined with low-dosed imidacloprid. No significant difference in the aphid mortality was observed between the oil formulations. Mass spectrometry analyses of aphids treated with the low dosedimidacloprid plus the plant oil formulations detected similar concentrations of imidacloprid between the treatments. In field trial bioassays against aphids, significantly decreased aphid population were observed in the pepper plants treated with soybean oil formulation combined with the low-dosed imidacloprid, while aphid population dramatically increased in the pepper plants treated with the low-dosed imidacloprid alone. These results suggested that the plant oil formulations can be used as an environmentally-friendly method for enhancing the insecticidal effectiveness, which may play a role in reducing the use of synthetic pesticide in agriculture.

• 대한화장품학회지
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• 제19권1호
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• pp.108-126
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• 1993

유화, 가용화, 겔화 등의 화장품 제형에서 폴리옥시에칠렌 토코페릴에테르의 기능에 대해 연구하였다. Liquid paraffin의 유화에 있어서 POE(10)TE는 O/W 유화에서 우수한 유화능을 나타내었다. W/o 및 O/W 유화에서 oil 과 polyol 류의 함량 증가가 점도에 미치는 영향에 대해서도 연구하였다. O/W 유화에서 점도는 liquid paraffin 약 70% 함량에서 급격히 증가하기 시작하였으며, propylene glycol 첨가시는 약간의 증가만 나타내었다. 그러나 W/O 유화에서 점도는 liquid paraffin의 함량 증가에 따라 감소하였고, propylene glycol함량 증가에 대해서도 감소하는 경향을 나타내었다. Perfume oil의 가용화에 있어서 POE(18)TE는 우수한 가용화능을 나타내었다. Poe(n)TE의 gelling effect는 폴리옥시에칠렌의 사슬의 증가에 따라 50 mol 까지는 상승하는 현상을 나타내었다.

• 대한화장품학회지
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• 제46권4호
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• pp.383-390
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• 2020

블루라이트는 380 ~ 450 nm 사이의 파장에 존재하는 파란색 계열의 빛으로 활성산소를 유발하여 노화를 불러일으키는 것으로 보고되었으며, 이에 따라 블루라이트 차단 효과에 대한 관심이 높아지고 있다. 본 연구에서는 자외선 차단제품에서 오일의 극성도, 제형의 점도, 유화제의 종류, 유화입자, 무기자외선 차단제 등이 블루라이트 차단 효과에 미치는 영향에 대해 조사해 보았다. 그 결과 오일의 극성도가 유기자외선차단제의 극성과 유사해질수록 블루라이트 차단율이 높아지는 것으로 확인되었으며, 제형의 점도가 증가할수록 높은 블루라이트 차단율을 나타냈다. 유화제의 종류 및 유화 입자는 블루라이트 차단 효과에 미치는 영향이 미비하였고, 무기자외선 차단제 함유 여부가 블루라이트 차단율에 큰 영향을 주는 인자 중 하나로 나타났다. 이러한 결과들은 블루라이트 차단 효율을 효과적으로 높일 수 있으며, 앞으로 블루라이트 차단 제품 개발 및 제형 연구에 활용될 수 있을 것이다.