• 한국토양동물학회지
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• 제5권2호
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• pp.85-96
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• 2000

Actinolaimoidea 상과에 속하는 4신종을 기재 하였다. Neoactinolaimus gosungensis n. sp.는 체장이 2.2-2.4 mm 이고, b = 4.3-4.9; c = 10.7-11.2; 교접자는 60-62 $mu extrm{m}$이다. 구순부는 낮고, 비대칭형인 창침과 넓은 관공을 가진다. Egtitus arcuatus n. sp.는 체장이 1.5-1.8 $\mu\textrm{m}$이고, b = 3.6-4.2; c = 14-15, 창침은 배부로 굽었고, 식도의 기부에 식도장간개가 있다. Paractinolaimus tuberculantus n. sp.는 체장이 1.9-2.5 mm이고, b = 3.3-4.0, c = 7.2-8.8, 교접자는 66-69 $\mu\textrm{m}$이고 특이하게 몸통이 꼬였고, 식도의 기부에 결절이 있다. Carcharolaimus koriensis n. sp.는 체장이 1.7-1.9 mm이고, b = 3.6-4.5, c = 65-76 그리고 표피에 매우 뜨겁고 창침공이 큰 것이 특징이다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권6호
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• pp.2739-2745
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• 2014

Background: Health-related quality of life (HRQL) is a fundamental outcome in oncology patients and quality of life (QOL) assessment requires clinically relevant questionnaires. The purpose of this study was translation and definition of measurement properties and the clinical validity of Quality of Life Questionnaire (QLQ)-OG25 module in Persian patients with oesophagus, oesophagogastric junction (OGJ) or gastric cancers. Materials and Methods: The translation procedure followed European Organization for Research and Treatment of Cancer (EORTC) guidelines. Both EORTC QLQ-OG25 and a core questionnaire (EORTC QLQ-C30) were administered to patients with oesophagus (150), OG junction (93) and gastric (32) cancer undergoing multi-modal treatments. Convergent and discriminant validity, Cronbach's alpha coefficient and known-groups comparisons were used to examine reliability and validity. Results: In all, 275 patients (mean age 62 years) completed both questionnaires. Compliance rate was high and the questionnaire module was well accepted. We found good reliability for multi-item subscales of QLQ-OG25 (Cronbach's alpha coefficients 0.76-0.89). About 73% had TNM staging and scales distinguished between clinically distinct groups of patients. However, patients in palliative group experienced compromised functional status and worse treatment-associated symptoms than those in the potentially curative group. Test-retest scores were consistent. Multi-trait scaling analysis demonstrated good convergent and discriminant validity. Conclusions: Overall, the Persian version of QLQ-OG25 demonstrated psychometric and clinical validity that supports its application as a supplement to the original tool (EORTC QLQ-C30) when assessing HRQL in patients with upper-gastrointestinal (GI) cancer both in curative and palliative phases.

• Radiation Oncology Journal
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• 제37권2호
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• pp.134-142
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• 2019

Purpose: The aim is to study the dependence of deformable based auto-segmentation of head and neck organs-at-risks (OAR) on anatomy matching for a single atlas based system and generate an acceptable set of contours. Methods: A sample of ten patients in neutral neck position and three atlas sets consisting of ten patients each in different head and neck positions were utilized to generate three scenarios representing poor, average and perfect anatomy matching respectively and auto-segmentation was carried out for each scenario. Brainstem, larynx, mandible, cervical oesophagus, oral cavity, pharyngeal muscles, parotids, spinal cord, and trachea were the structures selected for the study. Automatic and oncologist reference contours were compared using the dice similarity index (DSI), Hausdroff distance and variation in the centre of mass (COM). Results: The mean DSI scores for brainstem was good irrespective of the anatomy matching scenarios. The scores for mandible, oral cavity, larynx, parotids, spinal cord, and trachea were unacceptable with poor matching but improved with enhanced bony matching whereas cervical oesophagus and pharyngeal muscles had less than acceptable scores for even perfect matching scenario. HD value and variation in COM decreased with better matching for all the structures. Conclusion: Improved anatomy matching resulted in better segmentation. At least a similar setup can help generate an acceptable set of automatic contours in systems employing single atlas method. Automatic contours from average matching scenario were acceptable for most structures. Importance should be given to head and neck position during atlas generation for a single atlas based system.

• Asian Pacific Journal of Cancer Prevention
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• 제15권14호
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• pp.5889-5893
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• 2014

Over-expression of epidermal growth factor receptor (EGFR) has been identified as a common feature associated with clinical outcome in many types of cancer, including squamous cell carcinoma of the oesophagus (SCCO). However, the clinical importance of EGFR over-expression in SCCO remains unsettled as conflicting results exist. Therefore we carried out the present meta-analysis of published studies for clarification. A total of 13 studies including 1, 150 patients were enrolled. EGFR over-expression was positive in 722 of these cases. With EGFR over-expression, patients had higher depth of invasion, vascular invasion, and poor prognosis. However, expression had no relation with degree of differentiation, histological grade, lymph node metastasis, clinical stage or lymphatic invasion. EGFR over-expression is probably a valuable predictor for the T stage, vascular invasion and OS, and it could be used as a poor prognosis indicator for the esophageal SCC patients. Targeting therapy to EFGR should be considered to the combined treatment in SCCO.

• 대한수의학회지
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• 제38권1호
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• pp.147-159
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• 1998

A survey of the internal parasites in 115 fishes of Ophicephalus argus was carried out in Kyungpook province during the period from January 1995 to November 1997. A species of trematode from the stomach and a species of nematode from the caeca of the fishes was discovered respectively. The trematode was identified as Azygia hwangtsinyi (Tsin, 1993) and the nematode as Pingus sinensis ($Hs\ddot{u}$, 1993). The fluke was pressed at thick of 0.1mm~0.2mm between slide glasses and fixed in 70% ethyl alcohol solution. The fluke was washed with tap water after fixation and stained with hematoxylin-carmin and mounted in balsam through routine methods. The nematode was fixed in 5% formalin solution and mounted with lactophnol or glycerine jelly. Morphology : Arygia hwantsinyi ; The fluke is elongate body with approximately parallel margins and rounded extremities in pressed preparations(Fig 1). The cuticle is unarmed. The oral sucker is ventro-subterminal in position. The ventral sucker is slightly smaller than oral sucker and positioned at 14.2% of body length from the oral sucker. The cirrus sac and genital pore is in mid-ventral line, slightly anterior to the ventral sucker. The oral sucker is succeeded by a well developed muscular pharynx. It is succeeded by a short inverted Y-shaped oesophagus. The inner wall of oesophagus is consisted of many fine folded membrane. The fine tubes of esophagus pass into the intestinal heads which are distended and presented a marked borderline between the fine tube and intestinal heads. The Intestinal heads start at level of pharynx and pass caudad in a zigzag course to end quite near caudal margin. The uterine coils occupy the intercecal area between the level of the cephalic margin of the ovary and about the level of the ventral sucker. The uterus is filled with many eggs. The testes are round or oval and placed one behind the other generally a little diagonally. The posterior testis is placed at level of 75.1% of body length. The ovary is oval, placed ahead the anterior testis. The shell gland not discernible outline is contacted with ovary ahead it. The vitelline glands are consisted of small oval vesicles. The vesicles occupy extracecal regions and between a little posterior of the ventral sucker and near caudal margin. Pingus sinensis : Female ; The cuticle is smooth and the cervical alae are well developed. The mouth opening is small, triangular, and without lips. The anterior end bears four sub-medial papillae. The oesophagus is divided into a muscular and glandular portion. The nerve ring is situated just at the junction of the muscular and glandular portions of the oesophagus. The vulva which has a prominent flap, is placed behind the middle of the body about one-third of the length of the worm from the posterior extremity. The vagina is strongly muscularised and after running anteriorly about $68{\mu}$, divides itself into two broad uterine tubes with an anterior and a posterior one. There are a few eggs in the uterine tubes. The tail is slender, straight and pointed. The ovary extends almost to the posterior extremity. Male : Male is smaller than female. The tail is pointed, curved and carrying well-developed caudal alae. A prominent muscular precloacal sucker is characteristic. The spicules are equal and short. There are four pairs of pedunculated pre-anal papillae, of which the most anterior pair are situated just at the level anterior to the muscular sucker. Two pairs of pedunculated papillae are present before the anus. There are five pairs of post-anal papillae of which the most anterior pair and the second counted from the posterior end are ventral and more marked than the ones which are situated laterally.

• Applied Microscopy
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• 제24권3호
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• pp.34-45
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• 1994

This investigation has been carried out to examine the structure of digestive tract from Korean Leech, Erpobdella lineata, using light and electron microscope. The digestive tract is composed of mouth, pharynx, Oesophagus, six-chambered stomach, three-chambered intestine, rectum and anus. Stomach and intestine have not gastric or intestine ceca and consist of only straight tube. All digestive tracts from pharynx to rectum are covered with simple columnar epithelial cells. While the surfaces of endothelial cell of pharynx and rectum are covered with cuticular layer of about $0.3{\mu}m$ in thickness, stomach and intestine are covered with estimated $0.2-0.3{\mu}m$ and $0.5{\mu}m$ microvilli respectively. Circular folds were found only in first and second chambers of stomach, intestine and rectum, but not in pharynx and the other chambers (third to sixth) of stomach. The granules of $0.3-0.8{\mu}m$ and $0.5-1.0{\mu}m$ in diameter were observed in the cytoplasm of stomach endothelial cell. These granules were demonstrated to contain protein which showed a positive reaction to ninhydrin. It was also found that there are well-developed microvilli in the apical portion of intestine endothelial cell in which endocytosis occurs actively.

• Journal of Species Research
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• 제5권3호
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• pp.318-323
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• 2016

Acrobeles ciliatus (von Linstow, 1877) and Plectus parietinus (Bastian, 1865) are newly collected from Korea. Acrobeles is similar to those nematode belongs to Rhabditidae and Panagrolaimidae by having terminal bulb without medium bulb but different by having complex, vines shaped labial attachment. A. ciliatus differed from other Acrobeles species by lateral fields with two incisures, primary axils U-shaped, and secondary axils V-shaped. Head region set off with the neck, three high labial probolae present, each having 5 tines at inner margins and 5-7 at outer margins, and two elongate apical tines. Also, it differs from the longer female body. Plectus parietinus is distinguished from all other species of Plectus by the prominent hypodermal glands, the relatively small amphid, the distinct and well set-off lips and by the subdorsal distal caudal seta on the left side of the tail. Stoma without stylet. Oesophagus about 1/4 of total body length with terminal bulb. Anus ca. $100{\mu}m$ from posterior extremity. Vulva is at middle of body. Have spinneret on tail tip.

• Asian Pacific Journal of Cancer Prevention
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• 제15권14호
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• pp.5829-5833
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• 2014

Background: The role of processed meat in the aetiology of squamous cell oesophageal cancer has been explored in detail. Methods: In the time period 1990-2005, a case-control study was conducted in Montevideo, Uruguay including 2,368 participants (876 cases of oesophageal cancer and 1,492 controls). Relative risks, approximated by the odds ratios, were estimated by multiple unconditional logistic regression. Results: Processed meat was positively associated with oesophageal cancer (upper quartile vs lower quartile OR 2.30, 95%CI 1.72-3.07), whereas salted meat intake was positively associated with squamous cell oesophageal cancer (OR 3.82, 95%CI 2.74-5.33). Finally other cured meats were positively associated with oesophageal cancer (OR 1.65, 95%CI 1.22-2.22). Conclusions: It could be concluded that processed meat consumption could be an important risk factor for the aetiology of squamous cell oesophageal cancer in Uruguay.

• Journal of Radiation Protection and Research
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• 제22권1호
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• pp.47-58
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• 1997

MCNP4A 코드를 이용하여 MIRD 인형팬텀의 정면과 후방에서 입사하는 넓고 평행한 감마선빔에 대한 단위 공기커마당 유효선량 환산계수와 단위 플르언스당 장기의 등가선량을 계산하였다. 본 연구에서 고려한 감마선은 0.03-10 MeV 에너지 구간에서 20개의 단일에너지에 대해 수행되었다. 환산계수의 계산결과를 ICRP/ICRU의 연구결과 발표예정 출판물에 주어진 해당되는 값과 비교한 결과 편차 10%이내에서 일치하고 있다. 결과의 차이가 발생한 이유는 MIRD 팬텀과 ADAM/EVE 팬텀의 기하학적 차이가 주원인이며 또한 계산에 사용된 전산코드와 단면적 차이 등으로 판단된다. 특정 식도 모델을 사용한 결과로부터 얻어진 유효선량과 흉선과 췌장에 대한 등가선량을 채택함으로써 얻어지는 유효선량은 약간(최고 5%)의 차이를 보인다. 기타장기로부터 상부대장을 제외했을 때 본 연구에서 다루었던 감마선 선량학적 측면의 경우에서는 중요하지 않은 것으로 나타났다.

• Journal of Chest Surgery
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• 제31권11호
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• pp.1110-1115
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• 1998

식도절제와 식도와 위의 문합 혹은 식도와 대장의 문합등의 수술은 통상적으로 식도절제를 위한 개흉절개와, 식도 및 주위 림프절 절제, 광범위한 개복수술과 위 혹은 대장의 박리 등을 포함하고 있다. 또한 박리된 위 혹은 대장은 경부절개후 경부식도에 문합하게 된다. 1978년 Orringer 와 Sloan 등이 개흉술을 하지 않고 식도절제술을 최초로 시행한 이래 흉강내시경과 종격동경등을 이용한 여러 가지 수술방법이 개발되었다. 반면에 종격동 내시경을 이용한 식도박리(endoscopic microsurgical dissection of the oesophagus : EMDO) 1989년 이들 수술수기 개발자인 Buess, Kimfmuller, Naruhn과 Melzer 등에 의해 EMDO로 명명되었으며 Buess와 Becker에 의해서 임상에 응용되었다. 본 증례는 150cc의 빙초산을 먹은 후 식동협착(esophageal striture) 로 진단 받은 20세된 여자환자에서 종격동경(Operating Mediastinoscope)을 이용하여 식도를 박리 하면서 동시에 위와 식도를 문합할수 있게 박리하고 GIA 90을 이용하여 위문부와 식도부위를 절제한 후 점막이 보존되어있는 상부식도 부위에서 식도를 절제하고 위를 1이용하여 경부에서 식도와 위를 문합하였다. 수술 후 특이한 합병증 없이 수술 후 17일째 퇴원하였으며 현재 별다른 문제없이 외래 추적관찰중이다.