• 제목/요약/키워드: obstetrics

검색결과 3,694건 처리시간 0.025초

Supernumerary ovary on recto-sigmoid colon with associated endometriosis

  • Lim, Chul Kwon;Kim, Hee Jin;Pack, Joon Sook;Ha, Joong Gyu;Yang, Yun Seok;Lee, Hye Kyung;Kim, Seung Hyun
    • Obstetrics & gynecology science
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    • 제61권6호
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    • pp.702-706
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    • 2018
  • A supernumerary ovary is a rare gynecological anomaly, and is usually excised due to its malignant transformation potential. We report a case of a supernumerary ovary and endometriosis situated on the anterior rectosigmoid colon. When laparoscopy was conducted, a firm, 5-cm mass was discovered on the anterior rectosigmoid colon along with normal ovaries. In this case, the discovery of a supernumerary ovary implied the presence of endometriosis. It is unusual for endometriosis and a supernumerary ovary to exist simultaneously.

Split hand/foot malformation with long-bone deficiency and BHLHA9 duplication: A prenatal diagnosis report

  • Cho, In Ae;Park, Ji Kwon;Baek, Jong Chul;Ha, A Na;Kang, Min Young;Lee, Jae Ik;Park, Ji Eun;Shin, Jeong Kyu;Choi, Won Jun;Lee, Soon Ae;Lee, Jong Hak;Paik, Won Young
    • Journal of Genetic Medicine
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    • 제12권2호
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    • pp.123-127
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    • 2015
  • Distal limb deformities are congenital malformations with phenotypic variability and high genetic heterogeneity. Split hand/foot malformation, also known as ectrodactyly, is a congenital limb malformation characterized by a defect of the central rays of the hands and/or feet. Split hand/foot malformation with long-bone deficiency (SHFLD) is a rare condition related to a 17p13.3 duplication. Recently, genomic duplications encompassing BHLHA9 have been associated with SHFLD. We report a case of SHFLD presenting with campomelia of the right femur, bilateral agenesis of fibulae, bilateral club feet, and oligosyndactyly of the hands and feet, that was associated with a 17p13.3 duplication, as determined prenatally using array comparative genomic hybridization.

Expression and Effects of JMJD2A Histone Demethylase in Endometrial Carcinoma

  • Wang, Hong-Li;Liu, Mei-Mei;Ma, Xin;Fang, Lei;Zhang, Zong-Feng;Song, Tie-Fang;Gao, Jia-Yin;Kuang, Ye;Jiang, Jing;Li, Lin;Wang, Yang-Yang;Li, Pei-Ling
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권7호
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    • pp.3051-3056
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    • 2014
  • Previous studies have demonstrated that JMJD2A is a potential oncogene and is overexpressed in human tumors. However, its role in the endometrial carcinoma remains largely unknown. In this study, we discovered that JMJD2A was overexpressed in endometrial carcinoma, using immunohistochemistry, quantitative realtime polymerase chain reaction, and western blotting. Downregulation of JMJD2A led to reduced endometrial carcinoma RL95-2 and ISK cell proliferation, invasion and metastasis as asessed with cell counting kit-8, cell migration and invasive assays. Collectively, our results support that JMJD2A is a promoter of endometrial carcinoma cell proliferation and survival, and is a potential novel drug target.