Uhm, Mi-Young;Kim, Young-Ki;Lee, Scott S.;Suh, Euy-Hoon;Chang, Hong-Hee;Lee, Hee-Chun;Lee, Hyo-Jong;Yeon, Seong-Chan
Journal of Veterinary Clinics
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v.26
no.3
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pp.205-211
/
2009
Perioperative pain relief is essential in veterinary practice. However, the cat is one of the most poorly understood species regarding pain control management. Ovariohysterectomy(OHE) produces considerable postoperative pain in cats. Practitioners are often reluctant to administer analgesics due to lack of familiarity with available drugs, concern about side effects, or frustration with the need for record keeping of controlled substances. The purpose of this study was to determine if intraperitoneal administration of bupivacaine can provide relief of pain following OHE in cats. Twelve healthy female cats were randomly divided into two groups. OHE was performed under general inhalation anesthesia. Just prior to complete closure of the linea alba, 6 cats in SAL group received 0.88 ml/kg 0.9% saline, 6 cats in BUP group received 4.4 mg/kg 0.75% bupivacaine diluted to an equivalent volume with saline in the intraperitoneal space. Cats were scored at 0, 1, 2, 4, 8, 12 and 24 hours post-extubation by one observer. Cats were evaluated using a visual analogue scale(VAS) and composite pain scale(CPS) that included physiologic variables. There were no significant differences in body weight, anesthesia time, surgery time, and incision length between the two groups. Cats in the BUP group had significantly(p<0.05) lower VAS-pain scores than cats in the SAL group at 4, 8, 12 hours after surgery. Cats in the BUP group had significantly lower CPS scores than cats in the SAL group at 8, 12 hours after surgery. No adverse side effects were observed. These results support that the intraperitoneal administration of bupivacaine following OHE can be used for the prevention of postoperative pain and pain-induced behavioral changes in cats.
Purpose: Contrast, sharpness, enhancement, and density can be changed in digital systems. The important question is to what extent the changes in these variables affect the accuracy of caries detection. Materials and Methods: Forty eight extracted human posterior teeth with healthy or proximal caries surfaces were imaged using a photostimulable phosphor (PSP) sensor. All original images were processed using a six-step method: (1) applying "Sharpening 2" and "Noise Reduction" processing options to the original images; (2) applying the "Magnification 1:3" option to the image obtained in the first step; (3) enhancing the original images by using the "Diagonal/"option; (4) reviewing the changes brought about by the third step of image processing and then, applying "Magnification 1:3"; (5) applying "Sharpening UM" to the original images; and (6) analyzing the changes brought about by the fifth step of image processing, and finally, applying "Magnification 1:3." Three observers evaluated the images. The tooth sections were evaluated histologically as the gold standard. The diagnostic accuracy of the observers was compared using a chi-squared test. Results: The accuracy levels irrespective of the image processing method ranged from weak (18.8%) to intermediate (54.2%), but the highest accuracy was achieved at the sixth image processing step. The overall diagnostic accuracy level showed a statistically significant difference (p=0.0001). Conclusion: This study shows that the application of "Sharpening UM" along with the "Magnification 1:3" processing option improved the diagnostic accuracy and the observer agreement more effectively than the other processing procedures.
The prime objective of many facial wrinkle-reduction treatments is to achieve visible improvement. Thus the visibility of before/after treatment differences is often part of an efficacy assessment. This paper investigates whether the background knowledge of the people acting as observers in such assessments is of impact on the results: e.g. the subjects themselves are familiar with their faces, skin professionals have much experience in judging skin quality, and thus both might be more sensitive to small changes. In a clinical study 44 Female subjects were regularly treated during a period of 12 weeks with one of three wrinkle-reduction methods: K, Land M (placebo). Photographs were taken before treatment and at 6 and 12 weeks. The photographs were judged by 3 types of observers:ㆍ24 Lay observers were given the 0&6-week and the 0&12-week photo pairs of all subjects to indicate the one with the least wrinkles in a two-alternative forced-choice (TAFC) procedure.ㆍThe subjects themselves were given the 0&6-weel and the 0&12-week pair of their own photos (8 replications) to indicate the photo with the least wrinkles (TAFC).ㆍA trained panel of skin professionals (N=3) each gave 9-point Fitzpatrick wrinkle-severity scores for all individual 0-week and 12-week photos. We found that the lay observers perceived the same differences as the subjects themselves: significant improvements after 12 weeks for treatment K (p<0.0005 and p=0.005, respectively), no visible effects for treatments Land M, and, most importantly, a significant difference between treatments K and M/placebo (p=0.02 and p=0.04, respectively). Also the trained panel found this difference between K and M (p=0.013), but here it was due to a significant deterioration over time of the 'placebo-treated' wrinkles (M, p=0.03). Thus in conclusion we have found no indications that extra knowledge - in the form of familiarity with the own face or in the form of professional training - results in the identification of more treatments that show significantly visible wrinkle-reduction.
Park, Jeong-Hoon;Yoon, Ji-Young;Kim, Eun-Jung;Yoon, Ji-Uk;Choi, Byung-Moon;Ahn, Ji-Hye
Journal of Dental Anesthesia and Pain Medicine
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v.18
no.5
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pp.295-300
/
2018
Background: Removal of the plate following Le Fort I osteotomy and BSSO (bilateral sagittal split osteotomy) is a common procedure. However, patients who undergo plate removal experience intense pain and discomfort. This study investigated the half-maximal effective concentration ($Ce_{50}$) of remifentanil in the prevention of plate removal pain under sedation using dexmedetomidine. Methods: The study evaluated 18 patients, between 18 and 35 years of age, scheduled for elective surgery. Remifentanil infusion was initiated after sedation using dexmedetomidine, and started at a dose of 1.5 ng/mL on the first patient via target-controlled infusion (TCI). Patients received a loading dose of $1.0{\mu}g/kg$ dexmedetomidine over 10 min, followed by a maintenance dose of $0.7{\mu}g/kg/h$. When the surgeon removed the plate, the patient Modified Observer's Assessment of Alertness/Sedation (MOAA/S) score was observed. Results: The Ce of remifentanil ranged from 0.9 to 2.1 ng/mL for the patients evaluated. The estimated effect-site concentrations of remifentanil associated with a 50% and 95% probability of reaching MOAA/S score of 3 were 1.28 and 2.51 ng/mL, respectively. Conclusion: Plate removal of maxilla can be successfully performed without any pain or adverse effects by using the optimal remifentanil effect-site concentration ($Ce_{50}$, 1.28 ng/mL; $Ce_{95}$, 2.51 ng/mL) combined with sedation using dexmedetomidine.
Journal of the Korea Fashion and Costume Design Association
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v.6
no.3
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pp.45-53
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2004
Natural dyes have poor colorfastness as a result of the exposure of the dyed fabric to sunlight encountered during the display or wearing. As colors on fabrics fade excessively under sunlight, it is a problem to infer and restore the historic textiles with natural-dyed fabrics to original colors. The object of this study is to analyse the factors affected to color change under light. In experimental, fifteen natural dyes were dyed by the Korean traditional dyeing methods onto natural fiber fabrics: cotton, silk, ramie, and flex. Total 49 dyed fabrics in combination with dyes and fibers were used for the specimen. The Weather-O-meter was used for evaluating the effects of exposure to light for 2.5 to 450 hours. The process of color changes in the CIEL *A*B* color-order system to the exposure time were determined by spectrophotometer at 10$^{\circ}$ observer. Sunlight exposure caused significant changes in the color of natural-dyed fabrics. The degree and nature of color changes on the fabrics were dependent on the combination of fiber and the type of dye used. The groups of violet(Lithospermum erythrorhizon Sieb.et Zucc.) and black color(Ailanthus altissima Swingle, Phus trichocarpa Miq) yielded excellent colorfastness to light. The group of indigo blue color(Polygonum tinctorium Lour.) was also very resistant to fading in both exposure except silk. Whereas the dye groups of Red, Yellow, Orange, Brown colors indicated greatest changes in fading, particularly Carthamus tinctorius L.
Journal of the Korean Association of Oral and Maxillofacial Surgeons
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v.36
no.4
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pp.262-269
/
2010
Introduction: Accurate diagnosis and treatment planning are very important for orthognathic surgery. A small error in diagnosis can cause postoperative functional and esthetic problems. Pre-existing 2-dimensional (D) chephalogram analysis has a high likelihood of error due to its intrinsic and extrinsic problems. A cephalogram can also be inaccurate due to the limited anatomic points, superimposition of the image, and the considerable time and effort required. Recently, an improvement in technology and popularization of computed tomography (CT) provides patients with 3-D computer based cephalometric analysis, which complements traditional analysis in many ways. However, the results are affected by the experience and the subject of the investigator. Materials and Methods: The effects of the sources human error in 2-D cephalogram analysis and 3-D computerized tomography cephalometric analysis were compared using Simplant CMF program. From 2008 Jan to 2009 June, patients who had undergone CT, cephalo AP, lat were investigated. Results: 1. In the 3 D and 2 D images, 10 out of 93 variables (10.4%) and 11 out 44 variables (25%), respectively, showed a significant difference. 2. Landmarks that showed a significant difference in the 2 D image were the points frequently superimposed anatomically. 3. Go Po Orb landmarks, which showed a significant difference in the 3 D images, were found to be the artificial points for analysis in the 2 D image, and in the current definition, these points cannot be used for reproducibility in the 3 D image. Conclusion: Generally, 3-D CT images provide more precise identification of the traditional cephalometric landmark. Greater variability of certain landmarks in the mediolateral direction is probably related to the inadequate definition of the landmarks in the third dimension.
Kim, Young-Man;Park, So-Yeon;Choi, Houng-Sik;Kwon, Oh-Yun
Physical Therapy Korea
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v.3
no.2
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pp.49-54
/
1996
The purposes of this study were to measure skin temperature and blood flow on the contralateral upper extremity when heat is applied to one upper extremity, were to compare the effect of contrast bath. The subjects were 38 healthy adults with no history of peripheral vascular disease. The subjects of contrast bath were 18 persons and the subjects of warm bath were 20 persons. The subjects of one group were seated with their right arm in water($42^{\circ}C$) up to the mid-forearm. The subjects of the other group were seated with their right arm up to the mid-forearm in water which was changed from warm to cold using the contrast bath technique. The continually changing temperatures and blood flow were measured by an independent observer at intervals of 10, 15, 20, 25 and 30 minutes respectively after the start of the procedure. The results were as follows. The temperature of the warm bath group rose 4.28% over the pre-experimental temperatures and the temperature of the contrast bath group rose 3.41%. There was no statistically significant difference between the two groups. The blood flow of the warm bath group rose 8.31% over the pre-experimental blood flow and the blood flow of the contrast bath group rose 17.24%. There was a statistically significant between the two groups 20 minutes after the start of the procedure. Thus the contrast bath is a more effective method than the warm bath to increase blood flow.
Background: Postoperative pain is one of the most prevalent and bothersome issues found in the surgical department. Nowadays, there are various methods of acupuncture used for relieving pain without the complications found in some routine postoperative analgesics. These methods could be especially useful for high risk patients prone to complications from analgesics, such as transplantation recipients. The aim of this study was to evaluate the efficacy of electro-acupuncture on postoperative pain control after inguinal surgeries. Methods: Ninety male patients, who were referred to our department with indications of inguinal surgery, were included in the study and randomly divided into two groups, such as acupuncture and control. We used electro-acupuncture for the acupuncture group and no actual acupuncture (but placed needle electrodes similar to the acupuncture group) for the control group. Postoperative pain was quantified by a blind observer in both groups using a visual analogue scale (VAS) standard score before being compared. Results: Pain intensity and analgesic use were significantly higher in the control group (P < 0.05). In the acupuncture group, the VAS pain scores were significantly lower than the control group at 0.5, 1 and 2 hours post operation. When the opioid related side effects were compared for each group, the results showed that the number of subjects who experienced dizziness in the acupuncture group was significantly lower than the control group (P < 0.05). Conclusions: Acupuncture in patients, after inguinal surgery, can reduce the need of analgesics, which also directly reduces the complications that may occur when analgesics are used in relieving pain postoperatively.
Gott, Carter, Leslie, Bostrom and so on, as Descartes did, have made the evidence that is "I am here as an observer" to support many other beliefs. Bostrom and others who studied observation selection effects are missing two points. First, the self-consciousness information of the ones who just came up is distinct from that of the ones who have awoken. The awoken 'I' can trace back by memory to the past, but the 'I' who just came up can not. Second, when calculating credence, we must distinguish the ones in the possible worlds from the ones in the actual worlds. An estimate of credence where only one possible world is actualized among all possible worlds, differs fundamentally from that where all possible worlds are actualized. Keeping these two points in mind, we have explored what is the nature of the self-consciousness information of the one who just came up. We examine in depth the two human embryos thought experiment.
Hybrid rotor position estimation methods that integrate a fundamental model and high frequency (HF) signal injection are widely used for the wide speed-range sensorless control of interior permanent-magnet synchronous machines (IPMSMs). However, the direct transition of two different schemes may lead to system fluctuations or system instability since two estimated rotor positions based on two different schemes are always unequal due to the effects of parameter variations, system delays and inverter nonlinearities. In order to avoid these problems, a seamless transition strategy to define and construct a virtual q-axis inductance is proposed in this paper. With the proposed seamless transition strategy, an estimated rotor position based on a fundamental model is forced to track that based on HF signal injection before the transition by adjusting the constructed virtual q-axis inductance. Meanwhile, considering that the virtual q-axis inductance changes with rotor position estimation errors, a new observer with a two-phase phase-locked loop (TP-PLL) is developed to accurately obtain the virtual q-axis inductance online. Furthermore, IPMSM sensorless control with maximum torque per ampere (MTPA) operations can be tracked automatically by selecting the proper virtual q-axis inductance. Finally, experimental results obtained from an IPMSM demonstrate the feasibility of the proposed seamless transition strategy.
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