• 제목/요약/키워드: observed and censored times

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Regression Quantile Estimations on Censored Survival Data

  • 심주용
    • Journal of the Korean Data and Information Science Society
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    • 제13권2호
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    • pp.31-38
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    • 2002
  • In the case of multiple survival times which might be censored at each covariate vector, we study the regression quantile estimations in this paper. The estimations are based on the empirical distribution functions of the censored times and the sample quantiles of the observed survival times at each covariate vector and the weighted least square method is applied for the estimation of the regression quantile. The estimators are shown to be asymptotically normally distributed under some regularity conditions.

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Regression Analysis of Doubly censored data using Gibbs Sampler for the Incubation period

  • Yoo Hanna;Lee Jae Won
    • 한국통계학회:학술대회논문집
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    • 한국통계학회 2004년도 학술발표논문집
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    • pp.237-241
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    • 2004
  • In standard time-to-event or survival analysis, the occurrence times of the event of interest are observed exactly or are right-censored. However in certain situations such as the AIDS data, the incubation period which is the time between HIV infection time and the diagnosis of AIDS is usually doubly censored. That is the HIV infection time Is interval censored and also the time of the diagnosis of AIDS is right censored. In this paper, we Impute the Interval censored infection time using the conditional mean imputation and estimate the coefficient factor of the regression analysis for the incubation period using Gibbs sampler. We applied parametric and semi-parametric methods for the analysis of the Incubation period and compared the results.

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Iterative Support Vector Quantile Regression for Censored Data

  • Shim, Joo-Yong;Hong, Dug-Hun;Kim, Dal-Ho;Hwang, Chang-Ha
    • Communications for Statistical Applications and Methods
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    • 제14권1호
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    • pp.195-203
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    • 2007
  • In this paper we propose support vector quantile regression (SVQR) for randomly right censored data. The proposed procedure basically utilizes iterative method based on the empirical distribution functions of the censored times and the sample quantiles of the observed variables, and applies support vector regression for the estimation of the quantile function. Experimental results we then presented to indicate the performance of the proposed procedure.

Partially Parametric Estimation of Lifetime Distribution from a Record of Failures and Follow-Ups

  • Yoon, Byoung Chang
    • 품질경영학회지
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    • 제22권4호
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    • pp.59-78
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    • 1994
  • In some observational studies, we have often random censoring model. However, the data available may be partially observable censored data consisting of the observed failure times and only those nonfailure times which are subject to follow up. In this paper, we present an extension of the problem of partially parametric estimation of the survival function to such partially observable censored data. The proposed estimator treats the observed failure times nonparametrically and uses a parametric model only for those nonfailure times which are subject to follow-up. We discuss the motivation and construction of the proposed estimator and investigate the limiting properties of the proposed estimator such as asymptotic normality. Also, when the assumed parametric model is exponential, the asymptotic variance of the estimator is obtained. Furthermore, an example is given to compare the proposed estimator with the modified Kaplan Meier(MKM) estimator. From the results, it is shown that the relative efficiency of the proposed estimator is higher than that of the MKM estimator in the follow-up study with increasing time.

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A GEE approach for the semiparametric accelerated lifetime model with multivariate interval-censored data

  • Maru Kim;Sangbum Choi
    • Communications for Statistical Applications and Methods
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    • 제30권4호
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    • pp.389-402
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    • 2023
  • Multivariate or clustered failure time data often occur in many medical, epidemiological, and socio-economic studies when survival data are collected from several research centers. If the data are periodically observed as in a longitudinal study, survival times are often subject to various types of interval-censoring, creating multivariate interval-censored data. Then, the event times of interest may be correlated among individuals who come from the same cluster. In this article, we propose a unified linear regression method for analyzing multivariate interval-censored data. We consider a semiparametric multivariate accelerated failure time model as a statistical analysis tool and develop a generalized Buckley-James method to make inferences by imputing interval-censored observations with their conditional mean values. Since the study population consists of several heterogeneous clusters, where the subjects in the same cluster may be related, we propose a generalized estimating equations approach to accommodate potential dependence in clusters. Our simulation results confirm that the proposed estimator is robust to misspecification of working covariance matrix and statistical efficiency can increase when the working covariance structure is close to the truth. The proposed method is applied to the dataset from a diabetic retinopathy study.

정보적군집 크기를 가진 군집화된 구간 중도절단자료 분석을 위한결합모형의 적용 (Statistical Analysis of Clustered Interval-Censored Data with Informative Cluster Size)

  • 김양진;유한나
    • Communications for Statistical Applications and Methods
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    • 제17권5호
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    • pp.689-696
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    • 2010
  • 구간중도 절단자료는 감염 자료, 종양 발생 자료등 그 발생 시간을 정확하게 관측할 수 없는 경우에 흔히 발생되는 자료로 정확한 사건 발생 시간대신에 발생 전 마지막 관측시점과 발생 후 첫 번째 관측시점으로 구성된다. 이러한 종류의 자료는 Sun (2006)에 의해 자세하게 논의되었으며 관측 개체간의 독립성 가정 하에서 여러 가지 방법들에 의해 분석되어져 왔다. 본 논문에서는 관측 개체들이 군집으로부터 발생하여 더 이상독립성 가정이 적절하지 못한 경우를 고려한다. 특히 반응변수인 사건 발생 시간이 군집의 크기와 연관되어 있을 때, 이를 고려하기 위한 결합 모형을 제시한다. 제안된 모형은 림프계 필라리아병의 실제 자료에 적용한다.

Two-step LS-SVR for censored regression

  • Bae, Jong-Sig;Hwang, Chang-Ha;Shim, Joo-Yong
    • Journal of the Korean Data and Information Science Society
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    • 제23권2호
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    • pp.393-401
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    • 2012
  • This paper deals with the estimations of the least squares support vector regression when the responses are subject to randomly right censoring. The estimation is performed via two steps - the ordinary least squares support vector regression and the least squares support vector regression with censored data. We use the empirical fact that the estimated regression functions subject to randomly right censoring are close to the true regression functions than the observed failure times subject to randomly right censoring. The hyper-parameters of model which affect the performance of the proposed procedure are selected by a generalized cross validation function. Experimental results are then presented which indicate the performance of the proposed procedure.

Analysis of recurrent event data with incomplete observation gaps using piecewise models

  • Kim, Yang-Jin
    • Journal of the Korean Data and Information Science Society
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    • 제25권5호
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    • pp.1117-1125
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    • 2014
  • In a longitudinal study, subjects can experience same type of events repeatedly. Also, there may exist intermittent dropouts resulting in repeated observation gaps during which no recurrent events are observed. Furthermore, when such observation gaps have incomplete forms caused by the unknown termination times of observation gaps, ordinary approaches result in biased estimates. In this study, we investigate the effect of ignoring observation gaps and propose methods to overcome this problem. For estimating the distribution of unknown termination times, an interval-censored mechanism is applied and two cases are considered. Simulation studies are carried out to evaluate the performance of the proposed method. Conviction data of young drivers with several suspensions are analyzed to illustrate the suggested approach.

A Comparison of Size and Power of Tests of Hypotheses on Parameters Based on Two Generalized Lindley Distributions

  • Okwuokenye, Macaulay;Peace, Karl E.
    • Communications for Statistical Applications and Methods
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    • 제22권3호
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    • pp.233-239
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    • 2015
  • This study compares two generalized Lindley distributions and assesses consistency between theoretical and analytical results. Data (complete and censored) assumed to follow the Lindley distribution are generated and analyzed using two generalized Lindley distributions, and maximum likelihood estimates of parameters from the generalized distributions are obtained. Size and power of tests of hypotheses on the parameters are assessed drawing on asymptotic properties of the maximum likelihood estimates. Results suggest that whereas size of some of the tests of hypotheses based on the considered generalized distributions are essentially ${\alpha}$-level, some are possibly not; power of tests of hypotheses on the Lindley distribution parameter from the two distributions differs.

First Job Waiting Times after College Graduation Based on the Graduates Occupational Mobility Survey in Korea

  • Lee, Sungim;Moon, Jeounghoon
    • 응용통계연구
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    • 제25권6호
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    • pp.959-975
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    • 2012
  • Each year research institutions such as the Korea Employment Information Service(KEIS), a government institution established for the advancement of employment support services, and Job Korea, a popular Korean job website, announce first job waiting times after college graduation. This provides useful information understand and resolve youth unemployment problems. However, previous reports deal with the time as a completely observed one and are not appropriate. This paper proposes a new study on first job waiting times after college graduation set to 4 months prior to graduation. In Korea, most college students hunt for jobs before college graduation in addition, the full-fledged job markets also open before graduation. In this case the exact waiting time of college graduates can be right-censored. We apply a Cox proportional hazards model to evaluate the associations between first job waiting times and risk factors. A real example is based on the 2008 Graduates Occupational Mobility Survey(GOMS).