• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2005년도 춘계학술대회 논문집
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• pp.1501-1506
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• 2005

This paper presents the design of a multiple beam optical tweezers instrument used for manipulating micro/nano-sized components. The basic equations used in designing the optical tweezers are derived and the stable and time-sharing multiple beam optical tweezers are constructed with scanning mirrors. The laser beam passes through a series of optical components such as lenses, mirrors, and scanning mirrors, and overfills the entrance aperture of microscope objective, which gives a stable trap. By rotating the laser beam with the scanning mirror, the focal positions are translated in the specimen plane and multiple micro/nano-sized objects can be moved. The constructed optical tweezers is used to manipulate cells and liposomes simultaneously and to trap multiple nano-wires. The experiments prove that the developed optical tweezers can be a very versatile manipulation tool for studying gene therapy and nano device fabrication.

• 대한기계학회논문집A
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• 제24권3호
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• pp.728-734
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• 2000

An asymmetric actuator can be used to reduce the distance between the reflective mirror and objective lens of a small optical disk drive for use in the notebook-sized personal computer data storage devices. However, this asymmetric actuator is very sensitive to the subsidiary resonance which is caused by its rigid body motion. In this paper, an analytical approach using a simple lumped parameter system model is presented with a physical insight to investigate why the subsidiary resonance occurs. The finite element method is used to figure out the force and torque characteristics of the asymmetric actuator which are essential to understand the subsidiary vibration characteristics. The frequency responses are presented to examine how the subsidiary resonance is altered for various situations of having different thickness of a yoke and permanent magnet and of having a different magnet circuit. Finally, the design guidelines to avoid the subsidiary resonance will be presented.

• 한국정밀공학회지
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• 제21권6호
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• pp.188-196
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• 2004

The objective of this paper is to propose a new technology of the orthopaedic surgery using the combination of reverse engineering (RE) based on CT data and rapid prototyping (RP). The proposed technology utilizes symmetrical characteristics of the human body and capability of the combination of RE and RP, which rapidly manufactures three-dimensional parts from CT data. The original .stl data of injured extents are generated from the mirror transformation of .stl file fur uninjured extents. The physical shape before injuring is manufactured from RP using the original .stl data. Subsequently, pre-operative planning, such as a selection of proper implants, preforming of the implant, a decision of fixation locations and an insert position for the implant, an estimation of the invasive size, and pre-education of operators are performed using the physical shape. In order to examine the applicability and the efficiency of the proposed surgical technology, various case studies, such as a distal tibia commented fracture, a proximal tibia plateau fracture and an iliac wing fracture of pelvis, are carried out. From the results of case studies, it has been shown that the proposed technology is an effective surgical tool of the orthopaedic surgery reducing the operational time, the operational cost, the radiation exposure of the patient and operators, and morbidity. In addition, the proposed technology could improve the accuracy of operation and the speed of rehabilitation.

• 한국산학기술학회논문지
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• 제10권9호
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• pp.2179-2182
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• 2009

최근, 광학기계시스템에 새로운 구조 모델은 저비용, 고성능 및 품질의 개념설계에서 출발해야 할 필요성이 있다. 이런 관점에서, 기계적 구조의 개념설계와 연관된 구조적-위상적 형상은 구조적 강성과 감량과 같은 시스템 성능에 큰 영향을 끼친다. 본 연구에서는, 최적설계방법이 대구경 구조물의 설계단계에 제시되었다. 먼저, 위상 최적화법을 이용하여 구조물의 최적 배열과 보강방안을 얻었고, 사이즈 최적화와 다분야 최적기법을 사용한 세부 설계를 수행하였다. 그 일례로, 이 방법들을 대구경 구조물 설계에 적용하였다.

• 대한원격탐사학회지
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• 제20권1호
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• pp.47-55
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• 2004

We have constructed a level-1 processor to generate brightness temperatures using the direct-broadcast data from the passive microwave radiometer onboard Aqua satellite. Although 50-minute half-orbit data, called a granule, are being routinely produced by global data centers, to our knowledge, this is the first attempt to process 10-minute long direct-broadcast (DB) data. We found that the processor designed for a granule needs modification to apply to the DB data. The modification includes the correction to path number, the selection of land mask and the manipulation of dummy scans. Pixel-to-pixel comparison with a reference indicates the difference in brightness temperature of about 0.2 K rms and less than 0.05 K mean. The difference comes from the different length of data between 50-minute granule and about 10-minute DB data. In detail, due to the short data length, DB data do not always have correct cold sky mirror count. The DB processing system is automated to enable the near-real time generation of brightness temperatures within 5 minutes after downlink. Through this work, we would be able to enhance the use of AMSR-E data, thus serving the objective of direct-broadcast.

• 혜화의학회지
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• 제21권2호
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• pp.105-112
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• 2013

In oriental medicine, the skin of the face and the body is the mirror of the viscera and bowels. Skin aging is measured according to the elasticity and glossiness of the skin, which is perceived as a matter of fluid-humor within the realms of oriental medicine. Fluid-humor refers to normal body fluid that makes the skin moist and supple and the hair bright and glossy. If the body is lacking fluid-humor, the hair and skin will be dry and coarse. 'The improvement of fluid-humor (nutrition)' is facilitated based on the oriental physiological change theory for middle-aged women. A new study is therefore necessary to develop oriental herbal cosmetics for young women in their 20s. As yet, there has been no study on the effect of herbal cosmetics formulated for middle-aged women and used by young women in their 20s. This study aims to investigate the effect of 'the improvement of fluid-humor' for the skin of young women in their 20s within the theory of oriental medicine. This kind of study is essential for oriental skin care and the development of diverse oriental herbal cosmetics. To determine the effect of oriental herbal cosmetics on young women in their 20s based on the theory of oriental medicine, which says that a shortage of fluid-humor causes skin aging, this study has examined the skin conditions of young women in their 20s and how satisfied they are with oriental herbal cosmetics through an objective equipment-based measurement and subjective questionnaire survey.

• Journal of Korean Neurosurgical Society
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• 제41권3호
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• pp.171-176
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• 2007

Objective : The purpose of this study was to characterize the Rolandic fissure[Rf] and was to identify the Rf using the surface bony landmarks which can be usually exposed on craniotomy. Methods : After morphological evaluation of the Rfs using 21 Korean adult formalin fixed cadavers, craniometric measurement was carried out from the surface bony landmarks of nasion, glabella, bregma, and lambda. Results : The Rfs of both hemispheres did not show the mirror image. The Rfs ran forward and downward toward the sylvian fissure keeping the mean angle of $67^{\circ}$ from mid-sagittal line as elongated S-shape in left and the elongated reverse S-shape in right hemisphere. Connections between the Rf and the longitudinal fissure and between the Rf and the sylvian fissure were found in 3 [7.1%] and 2 [4.8%] of 42 hemispheres, respectively. Most Rfs extended superiorly to 2-3mm lateral to the most superomedial surface of hemispheres and extended inferiorly to 3-5mm superior to the sylvian fissures. The mean distances from the nasion, glabella, bregma, and lambda to the most superomedial aspect of the Rf were $18.8{\pm}0.9cm,\;16.6{\pm}0.8cm,\;5.2{\pm}0.6cm$, and $6.9{\pm}1.0cm$, respectively. The mean distance measured between the Rf and the nasion using traditional method was $18.4{\pm}0.6cm$. Conclusion : The distance between the Rf and the nasion roughly correspond within the range of mean 4 mm compared with that measured by the traditional measurement. These data may be more helpful to delineate the Rf after the placement of drapes for craniotomy.

• Journal of Yeungnam Medical Science
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• 제20권2호
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• pp.117-128
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• 2003

Thallium-201 scintigraphy is used to discriminate the malignant bone tumor from the benign by qualitatively and quantitatively, and to predict the response of preoperative chemotherapy in osteosarcoma, by comparing the changes of thallium uptake ratio after chemotherapy to the tumor necrosis ratio. Thallium-201 scintigraphy scan should be done prior to surgical biopsy. PICKER Prism 2000 gamma camera with high resolution parallel hole collimator is usually used for scanning. The patient is injected with 2-3mCi of Tl-201 and the early phase is checked in 30 minutes and delayed phase in 3 hours. The scan images are visually evaluated by a blinded nuclear medicine physician. We could evaluate true positive, true negative, false positive and false negative by the comparison of results with those of biopsy, and calculate positive and negative predictive value(%), sensitivity(%), specificity(%) and diagnostic accuracy(%). For the quantitative analysis of thallium uptake, we drew the region of interest on the tumor side and contralateral normal side as mirror image, and calculated the uptake ratio with dividing the amount of gamma count in tumor side by normal side. We could calculate the percent changes of thallium uptake ratio in early and delayed phase, and compare them to the ratio of tumor necrosis. Thallium-201 scintigraphy proved as useful imaging study to discriminate malignant bone tumor from benign, but had exception in giant cell tumor and low grade malignant bone tumors. We can use T1-201 scan to differentiate the benign from the malignant tumor, and to evaluate the response of preoperative chemotherapy or radiotherapy, and to determine the residual tumor or local recurrence. For the better result, we need to have a more detail information about false positive cases and a more objective and quantitative reading technique.

• 한국경영과학회지
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• 제41권3호
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• pp.75-96
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• 2016

This paper investigates the usefulness of drones in an urban delivery system. We define the vehicle and drone routing problem with time window (VDRPTW) and present a model that can describe a dual mode delivery system consisting of drones and vehicles in the metropolitan area. Drones are relatively free from traffic congestion but have limited flight range and capacity. Vehicles are not free from traffic congestion, and the complexity of urban road network reduces the efficiency of vehicles. Using drones and vehicles together can reduce inefficiency of the urban delivery system because of their complementary cooperation. In this paper, we assume that drones operate in a point-to-point manner between the depot and customers, and that customers in the need of fast delivery are willing to pay additional charges. For the experiment datasets, we use instances of Solomon (1987), which are well known in the Vehicle Routing Problem society. Moreover, to mirror the urban logistics demand trend, customers who want fast delivery are added to the Solomon's instances. We propose a hybrid evolutionary algorithm for solving VDRPTW. The experiment results provide different useful insights according to the geographical distributions of customers. In the instances where customers are randomly located and in instances where some customers are randomly located while others form some clusters, the dual mode delivery system displays lower total cost and higher customer satisfaction. In instances with clustered customers, the dual mode delivery system exhibits narrow competition for the total cost with the delivery system that uses only vehicles. In this case, using drones and vehicles together can reduce the level of dissatisfaction of customers who take their cargo over the time-window. From the view point of strategic flexibility, the dual mode delivery system appears to be more interesting. In meeting the objective of maximizing customer satisfaction, the use of drones and vehicles incurs less cost and requires fewer resources.

• 한국광학회지
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• 제15권6호
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• pp.583-590
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• 2004

비전을 이용한 광학식 검사공정이나 그 밖의 광학 현미경을 이용한 측정에 있어서 초점조절은 곧바로 측정 정밀도에 영향을 주는 중요한 요소이다. 본 논문에서는 핀홀 대신 광섬유를 사용하는 공초점 현미경 구조와 하나의 광섬유가 광원과 검출기의 역할을 동시에 수행하는 상반구성(reciprocal scheme)을 적용함으로써 간결하게 시스템을 구성하면서 광축 정렬을 용이하게 하였으며, 압전소자(PZT)를 이용한 광섬유 광원의 광축 방향 변조를 통해 방향 정보가 실린 초점오차 신호를 획득함으로써 빠른 초점조절을 구현하였다. 대물렌즈 변조방식과 달리 광원 변조방식은 현미경 시스템에 미치는 물리적 영향을 줄일 수 있으며, 기존의 장치에 탑재가 비교적 용이하다는 장점을 갖는다. 본 논문에서는 변조 진폭과 시편의 반사도 및 기울기 변화에 따른 초점오차 신호의 변화를 측정하였으며, 거울 시편에 대한 초점조절을 통해 본 시스템의 성능을 평가해 보았다. 또한 종방향 특성곡선의 반치폭 비교실험을 통해 광원 변조는 광축 방향 분해능에 영향을 주지 않음을 확인하였다.