• 비만대사연구학술지
• /
• 제2권2호
• /
• pp.71-75
• /
• 2023

Obesity is closely related to chronic diseases and cancer. The present case report aims to discuss the anti-obesity treatment strategy and the evaluation of the clinical progress in a patient with obesity and concurrent fatty liver disease. Following five months of treatment with liraglutide and rosuvastatin, the patient had a weight reduction of 3 kg (4.7%), a decrease in fasting blood sugar by 42 mg/dl (26.6%), a decrease in low-density lipoprotein cholesterol by 82 mg/dl (60.2%), and decrease in alanine transaminase. This case report documented the treatment of a patient with common chronic diseases encountered in the outpatient setting. Based on the therapeutic effects documented in clinical and laboratory indices, the anti-obesity treatment plan significantly aided in managing chronic diseases.

• 한국산학기술학회논문지
• /
• 제10권6호
• /
• pp.1414-1423
• /
• 2009

본 연구는 복부초음파검사를 통하여 얻은 건강진단 결과로부터 지방간 유소견자의 비율을 파악하고, 비만, 간기능 및 고지혈증 지표들과 지방간과의 관련성을 검토할 목적으로 실시하였다. 연구대상은 2006년 7월부터 2007년 6월까지의 기간에 D시의 한 대학병원 건강검진센터에서 종합건강검진을 받았던 30세 이상 남성 772명이었으며, 연구결과, 조사대상자의 지방간 유소견율은 25.5%이었으며, 비만지표(체중, BMI, 체지방율, 허리둘레와 엉덩이둘레 비, 허리둘레와 신장 비), 간기능지표(AST, ALT, GGT) 및 고지혈증지표(TG, TC, HDL-C)들과 유의한 관련성을 갖고 있음을 알 수 있으며, 이는 연령과는 독립적으로 그 관련성이 있는 것으로 나타났다.

• Clinical and Experimental Pediatrics
• /
• 제58권5호
• /
• pp.165-171
• /
• 2015

Purpose: To analyze the correlation between serum alanine aminotransferase (ALT) and obesity indices including body mass index (BMI), body fat percentage (BFP), total fat mass (FM), truncal fat mass (TFM), waist circumference (WC), and waist-to-height ratio (WHtR) in Korean adolescents. Methods: This was a cross-sectional study based on data derived from the 2010-2011 Korean National Health and Nutrition Examination Surveys (KNHANES). Subjects were Korean adolescents aged 10-18 years (871 total; 475 boys and 396 girls) who participated in KNHANES. Results: In both sexes, BMI, FM, TFM, WC, and WHtR were higher when ALT levels were in the 4th quartile. In boys, there was a significant positive correlation between ALT level and BMI, BFP, FM, TFM, WC, and WHtR (r=0.55, P<0.0001 for BMI; r=0.52, P<0.0001 for BFP; r=0.58, P<0.0001 for FM; r=0.61, P<0.0001 for TFM; and r=0.56, P<0.0001 for WC; r=0.62, P<0.0001 for WHtR), and the correlation coefficient was higher than that in girls. Conclusion: Our results suggest a significant positive association between serum ALT level and obesity indices in male adolescents.

• Nutrition Research and Practice
• /
• 제9권3호
• /
• pp.249-255
• /
• 2015

BACKGROUD/OBJECTIVES: This study was conducted in order to investigate the effect of peanut sprout extracts (PSE) on health indices in overweight and obese women (BMI $${\geq_-}23kg/m^2$$). SUBJECTS/METHODS: Subjects were divided into three groups by double-blind randomized trial; the Placebo group (n = 15) and the Low PSE group (2.6 g PSE/day, n = 15), and the High PSE group (5.8 g PSE/day, n = 15). Subjects consumed 12 capsules per day, three times a day, 30 min before meals, for 4 weeks. Anthropometric data, blood biochemical variables, and dietary intake were evaluated before and after the experiments. RESULTS: In the Low and High PSE group, the waist circumference showed a significant decrease between pre- and post-test. In the Low PSE group, the reduction of systolic blood pressure between pre- and post-test was statistically significant. Serum LDL or triglyceride levels in both Low and High PSE groups were significantly decreased, and serum alanine transaminase and aspartate transaminase were significantly decreased only in the Low PSE group. The parameters regarding erythrocyte and leucocyte counts showed no significant differences between pre- and post-test among groups, which suggested the safety of intake of peanut sprouts as a dietary supplement. CONCLUSIONS: This study indicates that PSE supplementation improves abdominal obesity and overall health indices. Therefore, an appropriate amount of peanut sprouts may be a plausible effective agent for obesity and obesity related health problems in obese women.

• 한국의류학회지
• /
• 제43권2호
• /
• pp.184-203
• /
• 2019

This study examines the multilateral characteristics of elderly body shapes by applying body measurement items and obesity indices (BMI, WHR, WHtR, WC, and flatness). The subjects were 397 males, 378 females aged 70-85 from the $6^{th}$ Size Korea and 132 males, 212 females aged 60-69, 596 males, 650 females aged 20-29 from the $7^{th}$ Size Korea. In order to examine the body size differences among age groups, age was divided into 7 groups (20-24, 25-29, 60-64, 65-69, 70-74, 75-79, and 80-85). Both elderly males and females showed lower values of height and weight than those in their 20s. However, abdominal obesity indices (WHR and WHtR) showed higher values in the elderly than those of their 20s; in addition, they showed larger mean values as age increased. The chest and arm circumference tended to decrease in elderly males as age increased; however, elderly females tended to decrease in thigh and calf circumference size. There were gender differences in body changing due to aging. Obesity frequency was significantly higher in the elderly than in the 20s. The study represents basic data for product design for the elderly.

• 대한지역사회영양학회지
• /
• 제10권3호
• /
• pp.253-263
• /
• 2005

This study was conducted to investigate health status of preschool children utilizing anthropometric values and serum biochemical indices. The subjects were 1,159 boys and 1,019 girls in Gumi day-care centers aged 4 to 6 years. The mean height and weight of 4, 5 and 6 year old children were 103.0 cm and 17.1 kg, 107.2 cm and 18.3 kg and 113.4 cm and 20.6 kg, respectively. By the obesity index criteria, $5\%$ of boys and $4\%$ of girls were obese whereas $10\%$ of boys and $9\%$ of girls were underweight. By the Kaup index criteria, $7\%$ of boys and $4\%$ of girls were obese. By the percentage of body fat criteria, $5\%$ of boys and girls were obese. The mean concentrations of serum total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol, Atherogenic Index and serum glucose were 154.1-156.5 mg/dL, 80.1-81.9 mg/dL, 46.8-47.4 mg/dL, 90.9-92.8 mg/dL, 2.34-2.39 and 76.4-77.8 mg/dL, respectively. Serum triglyceride level, AI and body fat percentage of obese children were significantly higher than other children and were significantly lower in HDL-cholesterol level (p < 0.05). In addition there were significant correlation between anthropometric values and serum biochemical indices : Kaup index and obesity index were positively correlated to the systolic blood pressure and diastolic blood pressure in boys and girls (p < 0.01) and to the triglyceride concentration in boys (p < 0.05). These results indicate the need of developing and implementation of nutrition education program for preschool children to prevent further development of childhood obesity and to maintain normal serum lipid profiles.

• 대한약침학회지
• /
• 제24권4호
• /
• pp.173-181
• /
• 2021

Objectives: The aim of this review was to appraise Korean studies published between 2010 and 2021 which examined the role of acupuncture in the treatment of obesity. Methods: We performed a search of the NDSL, KISS, RISS, OASIS, PubMed, EMBASE electronic databases for relevant animal researches, case reports, and clinical trials, using the following search terms: 'obesity', 'acupuncture', 'electroacupuncture', and 'pharmacopuncture'. We excluded previous reviews and meta-analyses, studies not related to obesity or acupuncture treatment, as well as studies conducted in countries other than Korea. We also excluded studies where relevant information on acupuncture treatment in obesity could not be obtained. Results: Most studies were conducted in animals, followed by case reports and clinical trials. In animal researches and case reports, pharmacopuncture was the most used intervention. In case studies, electroacupuncture, thread-embedding therapy, manual acupuncture, acupotomy, and auricular acupuncture were also used. In animal researches, pharmacopuncture treatment was associated with improvement in obesity indices. In the case of local obesity, specific acupuncture techniques such as thread-embedding therapy and pharmacopuncture were associated with significant improvements in local obesity, even when diet and exercise were not controlled for. Conclusion: Acupuncture treatment showed significant benefit in the treatment of obesity, with a local effect evident for certain approaches, such thread-embedding therapy and acupotomy.

• 한방비만학회지
• /
• 제3권1호
• /
• pp.7-16
• /
• 2003

Objectives : The lipolytic effects of catecholamines in adipose tissue are mediated by members of adrenergic receptors. This study was conducted to examine the effects of ${\beta}2-AR$ Gln27Glu (Q27E) polymorphism on obesity indices and risk among obesity clinic patients. Methods : 532 subjects, 38 men and 494 women, who attended a weight loss program in a local obesity clinic were analyzed. Height, weight, BMI, WHR and obesity index were measured or calculated. Body composition was measured by bio-impedance analysis. Genotype of ${\beta}2-AR$ polymorphism in codon 27 was analyzed by PCR-RFLP method. Serum concentrations of fasting glucose, total and HDL cholesterol, and triglyceride were determined by autobiochemical analyzer. Results: The Genotype distributions of ${\beta}2-AR$ gene were QQ type 81.3%, QE type 17.9% and EE type 8%. Therefore, the frequency of E allele of ${\beta}2-AR$ gene was 0.170 in the total subjects. The frequency of the ${\beta}2-AR$ variant genotype(QE+EE) was significantly higher in obese group($BMI{\geqq}25$) compared with non-obese group(p=0.027). Weight was significantly higher in variant(QE+EE) type compared with normal(QQ) type in total subjects(p=0.001), male(p=0.022) and female(p=0.013). BMI, obesity index and WHR were also significantly higher in QE+EE type. Body fat man was significantly higher in QE+EE type in total subjects(p=0.005) and female(p=0.027). When forward stepwise regression analysis was used to create a model of risk predictors of obesity($BMI{\geqq}25$), QE+EE type of ${\beta}2-AR$ gene was found to be a significant risk factor for obesity (p=0.042, ORs 1.597). Conclusions: QE+EE genotype of ${\beta}2-AR$ was associated with increased obesity indices and might be a significant risk factor for obesity.

• Journal of Nutrition and Health
• /
• 제45권1호
• /
• pp.57-63
• /
• 2012

This study investigated the relationship between total sugar intake and obesity indices in 362 female university students. This study was conducted using an anthropometric checkup and 3-day dietary records. Subjects were categorized according to the total sugar intake as < 33.3 g (group I, n = 90), 33.3-56.1 g (group II, n = 91), 56.1-83.8 g (group III, n = 91), ${\geq}$ 83.8 g (group IV, n = 90). No significant differences in age, weight, height, body mass index (BMI), or the percentage of body fat were observed among the four groups. Based on BMI, 20.2% were overweight, and the percentage of body fat was > 30% in 67.1% of all students sampled. Energy intake in each groups was 1,164.7 kcal, 1,488.6 kcal, 1,590.0 kcal, and 1795.8 kcal, respectively (p < 0.001). Total sugar intake in the groups was 20.5 g, 44.6 g, 68.3 g, and 111.8 g, respectively (p < 0.001). Carbonated beverages were identified as the most significant food source for total sugar intake in female university students. The next major foods were ice cream, milk, coffee, fruit, sugar, cookies, bread, chocolate, corn syrup, rice, onion, maple syrup, pickle, and sweet potato. As intake of total sugar increased, intake of energy also increased significantly. Mean daily intakes of fat and calcium/1,000 kcal were significantly higher in group IV than those in the other groups. Mean daily intakes of vitamin C and vitamin E/1,000 kcal were significantly higher in group III than those in the other groups. The percentage of subjects who consumed nutrients below the estimated average requirement was less in the higher total sugar intake group than that in the lower intake group. The obesity indices (weight, BMI, % body fat) were not associated with total sugar intake in the subjects. We conclude that total sugar intake does not seem to influence obesity indices in female university students.

• 한국산학기술학회논문지
• /
• 제14권9호
• /
• pp.4394-4401
• /
• 2013

본 연구의 목적은 건강검진을 받은 일반 성인들의 혈압과 혈청지질치 및 비만지표와의 관련성을 검토하고자 하였다. 조사대상은 2012년 한 대학교병원에서 건강검진을 받았던 20세 이상 일반 성인 2,734명(남자 1,344명, 여자 1,390명)을 대상으로 하였다. 조사는 해당 대학병원 연구윤리위원회(IRB)의 승인을 받은 후 대상자들의 종합건강검진 결과표와 문진표로부터 자료를 수집하였으며, 조사항목으로는 피조사자들의 성별, 연령, 안정 시 혈압(SBP, DBP), 혈청지질치(TC, HDL-C, LDL-C, TG, AI) 및 비만관련지표(BMI, 체지방률, 허리둘레) 등이었다. 연구결과, TC, TG, AI는 남녀 모두 고혈압군이 비고혈압군보다 유의하게 높았으며, HDL-C는 여자에서 비고혈압군이 고혈압군보다 유의하게 높은 반면, LDL-C는 고혈압군이 비고혈압군보다 유의하게 높았다. BMI, 체지방률, 허리둘레는 남녀 모두 고혈압군이 비고혈압군보다 유의하게 높았다. SBP와 DBP는 남녀 모두 연령, TC, TG, AI, BMI, 체지방률 및 허리둘레와 유의한 양의 상관관계를 보였다. 그러나 HDL-C와 LDL-C는 여자에서만 각각 음의 상관관계와 양의 상관관계를 보였다. 연령을 조정한 고혈압발생위험비는 남녀 모두에서 TC, TG, BMI, 허리둘레가 정상인 군보다 비정상인 군에서 유의하게 증가하였으며, HDL-C는 여자에서만, 체지방률은 남자에서만 유의하게 증가하였다. 이상과 같은 결과는 혈압이 여러 혈청지질치 및 비만지표들과 유의한 관련성을 갖고 있음을 시사한다.