• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.9 no.2
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• pp.1-9
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• 2014

Objectives : Many studies are being done in the method of experimental chuna science in China. The aim of this review is to understand and study the methods of experimental chuna science, focusing on the effects of chuna on circulatory system. Methods : We reviewed "實驗推拿學" and Chinese journals were searched using China National Knowledge Infrastructure(CNKI). Korean journals were searched using 3 Korean web databases(OASIS, NDSL, RISS). Results : By experimental chuna science, effect of chuna on blood pressure, cardiovascular system, hemorheologic system, blood flow velocity, circulation and lymphatic system were proved. Conclusions : Experimental chuna science is necessary for improvement of chuna to a higher level. In Korea, not many experimental studies are being done, especially in chuna and it has very narrow target diseases. For this reason we need to learn and adapt the methods of experimental chuna science of China.

• Journal of Korean Traditional Oncology
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• v.19 no.1
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• pp.1-24
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• 2014

Objectives : The purpose of this study was to present the clinical guidelines for gastric cancer. Methods : The literature on Western and Oriental medical treatment of gastric cancer were collected, analyzed and summarized from the Google Scholar, KIOM OASIS and PUBMED from 1993 to 2014. Results : Gastric cancer is the second most common cancer in Korea. In recent studies, applying integrative oriental and western medicine can suppress the tumor, improve the survival, the immune system, and the quality of life in gastric cancer. But there isn't still a unified protocol for gastric cancer treatment, so we have difficulty in clinical application. This study will be helpful for understanding and building systems for integrative gastric cancer treatment. Conclusion : Further studies on integrative gastric cancer treatment are needed to improve the survival of gastric cancer patients and build the clinical practice guidelines of gastric cancer.

• Journal of Korean Medical classics
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• v.26 no.1
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• pp.85-98
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• 2013

Objectives : Final assessment of realized on forecasting studies of the literature sector on traditional Korean medicine (2000-2010) revealed results as follows. Methods : We investigated the related peer-reviewed papers and research project reports through Oriental Medicine Advanced Searching Integrated System(OASIS) of Korea Institute of Oriental Medicine(KIOM) and several publishers. Results : Of total five projects, two were realized and three were partially done. The projects 'It wil be standardized by establishing the concept of traditional Korean medical terms' and 'CDs containing traditional medicine books from China, Japan and Korea wiil be released' were decided to be realized. In addition to those, the projects 'Systematic database will be build up for TKM books', 'translation and annotation versions on TKM old books will be completed', and 'A wide range of literature related to traditional medicine of each Asian countries' were concluded to be partially realized. Five projects on predicting TKM in the year 2006-2007 analyzed in 1996 were evaluated as realized or partially realized. Likewise, the five predictions should be reviewed whether it will be necessary in the future after assessment on their realization. Conclusion : Furthermore, it should be studies if the new projects are needed for the future in addition to the existing challenges.

• Journal of Korean Traditional Oncology
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• v.21 no.2
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• pp.1-35
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• 2016

Objectives : The aim of this preliminary study is to suggest a clinical approach on prostate cancer through the analysis of existing clinical practice guidelines or clinical studies. Materials and Methods : The data related on the treatment of prostate cancer were collected using various search engines such as Pub Med, KIOM OASIS, CNKI. Then, data were analyzed to evaluate the validity of recommendation of treatment. Results : Prostate cancer has the highest prevalence around the world. Recently, the incidence of prostate cancer in Korea is rapidly increasing. Especially, it was reported that incidence rate rose up to 80% by age 80 years. In recent studies, applying combined traditional and conventional medicine were reported to improve the survival, quality of life, immune function, and suppress of tumor growth in prostate cancer. However there has not been an objective and systemic clinical guideline for prostate cancer in Korean Medicine. Accordingly, it has been difficult for doctors to apply optimized therapeutic treatment in clinics. This study will show a preliminary approach to establish clinical practice guideline for prostate cancer of Korean Medicine. Conclusion : Further objective and systemic clinical studies by Korean Medicine are needed to develop more advanced clinical practice guidelines of prostate cancer.

• The Journal of Pediatrics of Korean Medicine
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• v.30 no.2
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• pp.23-30
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• 2016

Objectives The purpose of this study is to investigate recent clinical studies on effect of acupuncture for strabismus in Korea and other countries. We have analyzed 10 years (from 2006 to 2015) of case studies and randomized controlled trials (RCT) on effect of acupuncture for strabismus. Methods The search database includes Oasis, KTKP (Korean Traditional Knowledge Portal), Medline, Embase, and Cochrane library. To narrow the search, the following key search terms were used: 'strabismus, acupuncture'. The search was limited to the publication date from 2006 to 2015. 7 case studies and 5 control studies were selected for analysis. Results and Conclusions 1. The acupuncture treatment is effective for paralytic strabismus 2. The studies used BL1, GB1, ST2, TE23, GB15, EX-HN5, ST1, and LI4 acupoints and also an electroacupuncture treatment, which is 15 minutes of extraocular muscle stimulation, was used. 3. Degree of strasbismus was tested by Ocular motor range test, Corneal light reflex test, Ocular abducent scale test (Scott and Kraft, Diploptic range test).

• The Journal of Pediatrics of Korean Medicine
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• v.32 no.2
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• pp.26-42
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• 2018

Objectives The purpose of this study is to figure out the recent trend of the treatment for autism spectrum disorder (ASD) by comparing Korean and Chinese clinical studies. Methods National Digital Science Library (NDSL), Oriental medicine Advanced Searching Integrated System (OASIS), Research Information Sharing Service (RISS) and Korean Traditional Knowledge Portal (KTKP) were used to search Korean studies which were published from January, 2011 to May, 2017. Also Chinese National Knowledge Infrastructure (CNKI) and Wanfang data were used to search Chinese studies which were published from the same period. Key words of 'Autism' and 'Autism spectrum disorder' were used. Results 3 Korean studies and 21 Chinese studies were selected and analyzed to find out the most commonly used diagnostic criteria, treatments, including herbal medicine and acupuncture, and treatment assessment procedures. Conclusions As a result of comparing Korean and Chinese clinical studies for the treatment of ASD, both Korean and Chinese medicine treatments showed their effectiveness. However, there were some differences between two countries' clinical trends. In order for this study to be helpful, more highly evidenced clinical studies should be followed.

• The Journal of Pediatrics of Korean Medicine
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• v.34 no.3
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• pp.37-54
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• 2020

Objectives The purpose of this study is to analyze the treatment and treatment's effect for seizures disease in children by reviewing Korean clinical studies. Methods 13 articles which were published from August, 2002 to August, 2016 were obtained from the National discovery for science leader (NDSL), Research information sharing service (RISS), Google Scholar, and Oriental medicine advanced searching integrated system (OASIS) by using keyword 'Seizure', 'Convulsion', and 'Epilepsy'. Results Most of the study cases were with epilepsy children. The most frequently used herbal medicine was Gwakhyangjeonggi-san gami, and the most commonly used acupoints were LI4 and LR3. Treatment periods range from 13 days to 14 months, and all of the seizures were completely cured or relieved after the treatments. Conclusions This study shows that there are common symptoms and treatments for seizures in children. The reported different treatments can be used in primary medical care. Developing guideline standards of the seizure treatments can be possible with further studies.

• The Journal of Pediatrics of Korean Medicine
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• v.34 no.3
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• pp.55-66
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• 2020

Objectives The goal for this study is to find out the recent trends of the Korean medicine treatment on children and adolescents' somatic symptom and related disorder by reviewing case studies. Methods We found case study reports relevant to 'Korean medicine treatment on somatic symptom and related disorder' through Oriental Medicine Advanced Searching Integrated System (OASIS), National Discovery for Science Leader (NDSL) and Research Information Sharing Service (RISS). The age of the patients was limited to under 20. Results All reported articles showed that the treatments were selected based on both emotional problems and physical symptoms. Herbal medicine was the most commonly used method, and the other methods including acupuncture and psychotherapy were also used. Conclusions This study shows that the common Korean medicine treatment can be widely used for children and adolescents' somatic symptom and related disorder. Further research is needed to evaluate the effectiveness of the treatments, and to develop guidelines for the treatment.

• The Journal of Pediatrics of Korean Medicine
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• v.34 no.3
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• pp.81-96
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• 2020

Objectives This study aims to evaluate the effect of acupuncture combined with rehabilitation treatment for cerebral palsy in children. Methods 7 electro-database (PubMed, CENTRAL, CNKI, DBpia, KISS, OASIS, KJTK) were searched for using the keywords "cerebral palsy AND acupuncture" which study is designed in randomized controlled trials (RCTs). Results 10 out of 303 studies were included in analysis after screened. Acupuncture combined with rehabilitation treatment had a significant effect on motor function. Only 1 study reported minor adverse effects. Conclusions All of the studies have shown acupuncture combined with conventional rehabilitation treatment was effective in cerebral palsy. Additional well-designed studies are needed to justify the effectiveness of acupuncture in cerebral palsy.

• Proceedings of the Korea Society of Environmental Toocicology Conference
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• 2002.10a
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• pp.166-166
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• 2002

The response of environmental pollutants can be detected bioanalytically focusing on the source and matrices of concern. Cell culture bioassays are rapid and inexpensive, and thus have great potential for determination of environmental pollution. We have examined the estrogenic and dioxin-like activites of industrial wastewater using E-screen assay and EROD microbioassay. Influent and effluent wastewater were collected from four different industrial wastewater treatment plants, such as cosmetics, paints, textile producing and metal coating plant, and extracted using solid-phase extraction with Oasis＠HLB plus cartridge. Pollutants adsorbed to the cartridge were eluted with MTBE. MCF-7 cells were treated with extracts showed various estrogenic potential. The textile wastewater showed strong estrogenic activity and the others showed weak estrogenic activity, No effect was observed in the wastewater from paints producing plant. All extracts showed CYPIA inducing effects, indicating these samples contain dioxin-like chemicals. Bioanalytical results of effluents compared with influents could give us information about the incomplete wastewater treatment and biological potency caused by pollutants. [Supported by a Grant from the Korea Science and Engineering Foundation]