• Environmental Analysis Health and Toxicology
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• v.20 no.4 s.51
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• pp.297-302
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• 2005

The purpose of this study was to provide the standard method for the analysis of organophosphorous pesticides such as chlorpyrifos, diazinon, malathion and parathion in blood. We performed method validation for these pesticides in blood according to EURACHEM (A focus For Analytical Chemistry in Europe) guide. For the analysis of the pesticides, we used solid-phase extraction ,column (Waters Oasis $HLB^{(R)}$. After the extraction, the supernatants were evaporated to dryness under the nitrogen stream. They were analyzed by gas chromatography/mass spectrometry (GC/MS) after reconstituting with ethanol. Terbufos was used as an internal standard. To validate this method, we performed verification procedures with the following parameters: selectivity, linearity of calibration, accuracy, precision, limit of detection and quantification. Validation data according to Eurachem guide were adequate for our purpose for the analysis of chlorpyrifos, diazinon, malathion and parathion in blood.

• The Journal of Korean Medicine
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• v.41 no.1
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• pp.93-106
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• 2020

Objectives: The aim of this review is to ascertain whether Bojungikgi-tang and its modifications is more effective than non-specific management in chronic fatigue syndrome (CFS). Methods: We collected clinical trials to investigate the effects of Bojungikgi-tang and non-specific management on general symptoms, fatigue, and sleep quality in CFS patients. The databases used for data retrieval were Pubmed, Central Cochrane, CNKI, VIP, CiNii, OASIS, RISS, and Koreamed. We performed selection/exclusion process from the found records according to prespecified criteria, and assessed the final included trials according to the Cochrane risk of bias tool. The included studies were classified on the basis of interventions in experimental group. Results: Seven randomized controlled trials (476 participants) were eligible and their results were synthesized in the meta-analysis. The synthesis showed a substantial effect of Bojungikgi-tang (relative risk 0.20 [95% CI 0.13 to 0.31], Z=7.44, P<0.00001; I²=0%) and combination of Bojungikgi-tang and Sosiho-tang (relative risk 0.15 [95% CI 0.08 to 0.28], Z=5.85, P<0.00001; I²=0%) compared with non-specific management on improvement of general symptoms. However, we could not find sufficient clinical research records to determine their effects of improvement on fatigue and sleep quality. Conclusions: Bojungikgi-tang and its modifications are more effective than non-specific management for improvement of general symptoms in CFS post-treatment.

• The Journal of Korean Medicine
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• v.41 no.3
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• pp.247-259
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• 2020

Objectives: This review aims to investigate clinical studies related to bee venom pharmacopuncture for cancer patients and to analyze the research trend for further study. Methods: We searched for clinical studies using bee venom pharmacopuncture therapy on patients with cancer through the electronic databases including Pubmed, Cochrane library, OASIS, KISS, NDSL, and KMBASE. There was no restriction on language and publication date, and after selection/exclusion process, the study design, target disease, intervention details including acupoints, treatment frequency and period, outcomes, study results and adverse events were extracted. Results: Thirteen clinical studies were finally selected. There were a randomized controlled trial RCT about the effect of sweet bee venom pharmacopuncture on cancer-related pain, and three case series about chemotherapy-induced peripheral neuropathy. In case reports, there were nine studies about oligodendroglioma, plexiform neurofibroma, breast cancer, prostate cancer, lung cancer, urachal adenocarcinoma, malignant melanoma, and atypical squamous cells of undetermined significance. The bee venom therapy affected the improvement of outcomes such as symptoms, quality of life, tumor response, and lab findings. Conclusions: The present study found that bee venom therapy is applicable to the treatment of cancer patients, and showed some effect on various symptoms. However, due to insufficient number and quality of studies, well designed and high-quality clinical trials are necessary to confirm the effectiveness and safety of bee venom pharmacopuncture therapy in patients with cancer.

• The Journal of Korean Medicine
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• v.37 no.3
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• pp.1-12
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• 2016

Objectives: The abdominal examination is a diagnosis method for determining a morbid condition of the chest and abdomen by touching and pressing. This study reviewed research trends concerning the abdominal examination and suggested of future research directions for quantification of abdominal examination. Methods: A systematic literature search was carried out for relevant articles published between 2000 and 2016 in five databases such as Korean studies Information Service System(KISS), Oriental Medicine Advanced Searching Integrated System(OASIS), DataBase Periodical Information Academic (DBpia), National Digital Science Library and PubMed based on the Keywords 'abdominal examination'. Results: 128 articles were collected for analysis. Overview on the abdominal examination based on selected 17 articles. Then selected articles have been reclassified by diseases of clinical research and parameters for diagnosis of abdominal examination. Conclusions: Taken together, instrument for quantitative evaluation of abdomen characteristic fit to the traditional Korean Medicine have not yet developed. It is suggested that in order to dominate the market about abdominal examination in advance, more concern should be paid to establishing appropriate development of quantitative criteria and instrument. This review will help researcher to systematically understand and to develop Korean medical device as globally competitive device.

• The Journal of Korean Medicine
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• v.41 no.2
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• pp.122-136
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• 2020

Objectives: A case report is a detailed report of the symptoms, signs, diagnosis, treatment, and follow-up of an individual patient. The purpose of this study is to evaluate the quality of case reports from the Journal of Korean Medicine by the CARE (CAse REport) Guideline. Methods: Case reports published in the Journal of Korean Medicine from January 2016 to March 2020 were searched from Oriental Medicine Advanced Searching Integrated System (OASIS). We assessed the quality of reporting based on CARE (CAse REport) guideline as 'Sufficient', 'Not-Sufficient' and 'Not-Report'. Results: A total of 22 case reports were finally included for the assessment. The reporting items were reported as of reporting quality. After checking the result, there was a deviation in the sub-item reporting rate by a maximum 89.29%, a minimum 66.67% and a median 82.14% in case reports. Also after checking the quality in case reports by 28 detailed items in CARE guidelines, there were not reported 77% or more in the 5 sub-items 'Intervention adherence and tolerability', 'Informed consent', 'Adverse and unanticipated events', 'Diagnostic challenges', 'Patient perspective'. Conclusion: There is a need to improve the quality of case reports in the journal of Korean Medicine based on various studies using CARE guideline.

• Environmental Engineering Research
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• v.21 no.2
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• pp.145-151
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• 2016

Biodrying is a pre-treatment method that applies biological and mechanical concepts to drying solid waste. In Malaysia, municipal solid waste (MSW) is unseparated and contains a high level of moisture, making the use of technology such as solid waste burning unsuitable and harmful. MSW containing organic material can be processed naturally until the moisture content of the waste is reduced. This study on MSW biodrying was carried out on a laboratory scale to measure the percent moisture content reduction and to monitor temperature patterns under different ventilation periods. This work was conducted using five biodrying reactors volumes of 50 liters each. Reactors were ventilated for 5, 10, 15, 20 and 30 min every 3 h, with a 3 bar air supply. The duration of this process was 14 days for all samples. The results showed that the optimum ventilation time was 10 min, with an 81.84% reduction in moisture content, and that it required almost half of the electricity cost required for the 20 and 30 min ventilations.

• 대한상한금궤의학회지
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• v.8 no.1
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• pp.1-23
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• 2016

Objectives : The purpose of this paper is to find out the safe dose and clinical use for administration of Glycyrrhizae Radix in Shanghanlun(傷寒論). Methods : Web-databases(OASIS, NDSL, Pubmed, Google) were searched with keywords including 'Licorice', 'Pseudoaldosteronism', 'Glycyrrhizin', 'Testosterone' on 14/10/2016. The searched about 40 papers and books were reveiwed. Results : Glycyrrhizin(GL) and 3-monoglucuronyl glycyrrhetinic acid(3MGA) in Glycyrrhizae Radix are found to be the main compounds vulnerable for inducing pseudoaldosteronism. The dose range of Glycyrrhizae Radix in Shanghanlun prescriptions is from 0.25 g to 12 g as a daily administration, and this dose satisfies the guidelines of WHO, European Union, ABC etc. And risk factors contributing for personal sensitivities are old age(>60), female sex, liver dysfunction, hypokalemia, prolonged gastrointestinal transit time, anorexia nervosa, decreased 11-${\ss}$-hydroxysteroid dehydrogenase-2 activity and hypertension. Conclusions : As a result, dose of Glycyrrhizae Radix in Shanghanlun(傷寒論) is safe. However, the personal sensitivity and unexpected drug interactions are independent from doses of GL, so doctors should monitor those risk factors and symptoms of pseudoaldosteronism when administering Glycyrrhizae Radix.

• Proceedings of the Korea Information Processing Society Conference
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• 2002.11c
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• pp.1749-1752
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• 2002

최근 들어 B2B 기반의 전자상거래 프레임워크로 UN/CEFACT 과 OASIS 를 주축으로 하는 ebXML과 Microsoft, IBM, Ariba를 포함한 기업과 단체를 주축으로 하는 웹 서비스가 대두되고 있다. 이들은 모두 사용자 및 어플리케이션들이 정보를 저장하고 이를 공유할 수 있는 Registry 를 기반으로 서비스를 제공하고 있으며, 이를 위해 ebXML 은 ebXML Registry를, 웹 서비스는 UDDI Registry를 이용한다. ebXML 과 웹 서비스는 서로 다른 Registry 를 사용하고 있지만, Registry 를 사용하고 있지만, Registry 의 구조와 기능은 유사하거나 동일한 부분이 많다. 본 논문은 이에 착안하여 서로 유사하거나 동일한 역할을 가진 ebXML RIM의 구조와 UDDI의 데이터구조를 매핑함으로써, ebXML RIM 상에 UDDI 데이터구조를 표현하는 규칙을 찾고, 이를 이용하여 UDDI Registry Client의 서비스 요구를 ebXML Registry 를 이용하여 처리하는 UDDI Registry Server 를 설계한다. 이는 ebXML Registry 에 별도의 변경을 가하지 않고도 UDDI Registry Client 가 ebXML Registry 를 사용할 수 있게 한다.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.31 no.3
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• pp.84-96
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• 2018

Objectives : This study is designed for trend analysis of oriental medicine treatment for visual impairment. Methods : Research studies related to objectives were gathered through OASIS, KTKP, PUBMED with keywords such as "visual impairment", "myopia", "hyperopia", "presbyopia", "astigmatism" and analyzed. Results : As a result of searching domestic and overseas research on oriental medical treatment for visual impairment, 7 domestic research papers and 11 overseas research papers have been selected. Among those research papers, 15 of those are studies related to childhood or juvenile myopia. Acupuncture, ear acupuncture, herb medicine, periocular massage, eye muscle exercise and habit correction are used as treatment methods for visual impairment. 14 out of 17 research papers which mentioned treatment effect of oriental medicine reported oriental treatment of visual impairment is effective. Conclusions : Various types of oriental medical treatment could be effective in treating visual impairment. Thus, related in-depth research must be proceeded.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.31 no.3
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• pp.26-38
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• 2018

Objectives : The purpose of this study is to investigate the possibility of applying acupuncture to the treatment of meniere's disease, which has no definite treatment methods, by analyzing the latest clinical researches about acupuncture treatment of meniere's disease. Methods : A case study and Randomized Controlled Trial (RCT) related to the acupuncture treatment of meniere's disease were searched using domestic and international thesis search engines including OASIS, CNKI, J-STAGE, PubMed. This study include acupuncture treatment and acupuncture combined with other treatments such as herbal medicine. The search was limitied to the publication date from 2000 to 2018 with free full text. Results : 17 cases were selected. There were 7 case studies in Korea, 5 case studies in China, and 5 RCT papers in China. All 12 cases reported improvement in meniere's disease and all RCT studies showed significantly higher treatment effects in the experimental group than in the control group. Conclusions : Acupuncture treatment showed significant effects for meniere's disease when applied alone or in combination with other treatments. In the future, various systematic studies should be conducted only for acupuncture treatment.