• Title/Summary/Keyword: nuclear space

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Differential Diagnosis of Metastatic Bone Disease and Benign Bone Disease on Spine SPECT in Patients with Low Back Pain (요통 환자의 척추골 SPECT에서 골전이 병변과 양성골질환의 섭취 양상 분석을 통한 감별진단이 가능한가)

  • Lee, Seung-Hun;Choi, Yun-Young;Cho, Suk-Shin
    • The Korean Journal of Nuclear Medicine
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    • v.35 no.6
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    • pp.371-377
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    • 2001
  • Purpose: One or more abnormal vertebrae detected on bone scintigraphy is a common finding in clinical practice, and it could pose a diagnostic dilemma especially in cancer patients. as either metastasis or benign disease may cause scintigraphic abnormality. The purpose of this study was to determine whether additional spine SPECT has a role in differentiating malignant from benign lesions in patients with back pain. Materials and Methods: We reviewed spine SPECT studios obtained over a three-year period in 108 patients. Among them, forty-five patients with abnormal SPECT and clinically followed records were evaluated (20 cancer patients were included). Uptake patterns were classified as follows: 1. Body: diffusely increased uptake, linear increased uptake of end plate, segmental increased uptake, and cold defect, 2. Posterior element: posterior to body (pedicle), posterior to Intervertebral disc space (facet joint), and spinous process. Lesions were correlated with radiological findings and with final diagnosis. Results: Sixty-nine bone lesions were detected on SFECT images, including 18 metastases, 28 degenerative diseases and 21 compression fractures. Cold defect (6) and segmental increased uptake (5) were dominant findings in metastasis; linear increased uptake (12), and facet joint uptake (15) were in degenerative change; and diffuse increased uptake (9), and linear increased uptake (9) were in compression fracture. Conclusion: Cold defect and segmental increased uptake of body were characteristic findings of metastasis, but care should be taken because compression fracture also shows segmental increased uptake in some cases. Degenerative disease was easily diagnosed because of the typical finding of linear increased uptake of end plate and facet joint. Therefore, additional bone SPECT after planar bone scan would be helpful for differentiating metastasis from benign condition in cancer patients.

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Hemodynamics in Korean Hemorrhagic Fever (한국형(韓國型) 출혈열(出血熱)에서의 혈류역동학적(血流力動學的) 연구(硏究))

  • Han, Jie-Young;Lee, Jung-Sang;Koh, Chang-Soon;Lee, Mun-Ho
    • The Korean Journal of Nuclear Medicine
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    • v.8 no.1_2
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    • pp.1-11
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    • 1974
  • The author in an attempt to evaluate hemodynamic changes in the clinical stages of Korean hemorrhagic fever measured plasma volume, cardiac output and effective renal plasma flow utilizing radioisoto es during various phases of the disease. Cardiac output was measured by radiocardiography with external monitoring method using RIHSA. Effective renal plasma flow was obtained from blood clearance curve drawn by external monitoring after radiohippuran injection according to the method described by Razzak et al. The study was carried out in thirty-eight cases of Korean hemorrhagic fever and the following conclusions were obtained. 1. Plasma volume was increased in the patients during the oliguric-and hypertensive diuretic phases, while it was normal in the patients during the normotensive-diuretic phase. 2. Cardiac index was increased in the patients during the oliguric phase and was slightly increased in the patients at the hypertensive diuretic phase. It was normal in the other phases. 3. Total peripheral resistance was increased in the hypertensive patients during diuretic phase, while it was normal in the rest of phases. 4. Effective renal plasma flow was significantly reduced in the patients during the oliguric and diuretic phases as well as at one month after the oliguric onset. There was no significant difference between the oliguric and the early diuretic phases. Renal plasma flow in the group of patients at one month after the oliguric onset was about 45% of the normal, however, it returned to normal level at six months after the onset. 5. Clinical syndrome of relative hypervolemia was observed in some patients during the oliguric phase or hypertensive diuretic phase. Characteristic hemodynamic findings were high cardiac output and normal to relatively increased peripheral resistance in these cases. Relatively increased circulating blood volume due to decreased effective vascular space was suggested for the mechanism of relative hypervolemia. 6. Cardiac hemodynamic alteration returned to normal during late stage of the diuretic phase, while renal hemodynamic changes were normalized at six months after the onset.

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Characterization of Cement Waste Form for Final Disposal of Decommissioned Concrete Waste (해체 콘크리트 폐기물 최종처분을 위한 시멘트 고화체 특성 평가)

  • Lee, Yoon Ji;Hwang, Doo Seong;Lee, Ki Won;Jeong, Gyeong Hwan;Moon, Jei Kwon
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.11 no.4
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    • pp.271-280
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    • 2013
  • Since the decommissioning of nuclear plants and facilities, large quantities of slightly contaminated concrete waste have been generated. In Korea, the decontamination and decommissioning of the KRR-1, 2 at the KAERI have been under way. And concrete waste was generated about 800 drums of 200 L. The conditioning of concrete waste is needed for final disposal. The concrete waste is conditioned as follows: mortar using coarse and fine aggregates is filled void space after concrete rubble pre-placement into 200 L drum. Thus, this research has developed an optimizing mixing ratio of concrete waste, water, and cement and has evaluated characteristics of a cement waste form to meet the requirements specified in disposal site specific waste acceptance criteria. The results obtained from compressive strength test, leaching test, thermal cycling test of cement waste forms conclude that the concrete waste, water, and cement have been suggested to have 75:15:10wt% as the optimized mixing ratio. Also, the compressive strength of cement waste form was satisfied that including fine powder up to maximum 40wt% in concrete debris wastes about 75%. As a result of scale-up test, the mixture of concrete waste, water, and cement is 75:10:15wt% meet the satisfied compressive strength because the free water increased with and increased in particle size.

A Case of Cholethorax following Percutaneous Transhepatic Cholangioscopy (경피경간 담도내시경술 이후에 발병한 담즙흉 1예)

  • Park, Chan Sung;Lee, Soon Jung;Do, Gi Won;Oh, Ssang Yong;Cho, Hyun;Kim, Min Su;Hong, Il Ki;Bang, Sung Jo;Jegal, Yang Jin;Ahn, Jong-Joon;Seo, Kwang Won
    • Tuberculosis and Respiratory Diseases
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    • v.65 no.2
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    • pp.131-136
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    • 2008
  • Cholethorax (bilious pleural effusion) is an extravasation of bile into the thoracic cavity via a pleurobiliary fistula (and also a bronchobiliary fistula). It is an extremely rare complication of thoraco-abdominal injuries. It can be caused by congenital anomaly and also by hepatobiliary trauma, severe infection or iatrogenic procedures. The definitive diagnosis is made with aspiration of bilious fluid from the pleural space during thoracentesis, by finding a fistulous tract during endoscopic retrograde cholangiopancreatography (ERCP) or cholagioscopy, or with finding an abnormal pleural accumulation of radioisotope during hepatobiliary nuclear imaging. Its symptoms include coughing, fever, dyspnea and pleuritc chest pain. Herein we report on a case of cholethorax following performance of percutaneous transhepatic cholangioscopy (PTCS) to remove incidentally discovered common bile duct (CBD) stones.

Quantitation of Hepatic and Extrahepatic $^{99m}Tc-Tin$ Colloid Uptake in the Hepatocellular Diseases (간세포성 질환에서의 간 및 간외 $^{99m}Tc-Tin$ Colloid 섭취의 정량분석)

  • Park, Young-Ha;Kim, Choon-Yul;Kim, Sung-Hoon;Park, Seog-Hee;Park, Yong-Whee
    • The Korean Journal of Nuclear Medicine
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    • v.21 no.1
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    • pp.9-16
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    • 1987
  • It is well-known that hepatic scintigraphv have been found to be less sensitive and specific in the detection of the diffuse hepatocellular diseases than that of the space-occupying lesions. To obtain the higher diagnostic specificity and sensitivity, we, using the computer quantitation, have attempted to analyze hepatic and extrahepatic $^{99m}Tc-tin$ colloid uptake patterns in various diffuse hepatocellular diseases retrospectively. The studied groups consisted of 116 cases of normal, 67 cases of acute hepatitis, 112 cases of chronic hepatitis, 61 cases of liver cirrhosis, 47 cases of fatty liver, 12 cases of hepatoma and 9 cases of metastasis, making total 424 cases. Scintigraphic imagings were obtained in the anterior, right lateral and posterior projections using high-resolution collimation, and simultaneously these gamma data were acquisited into the computer system. Both large region of interest (ROI) using light pen and ROI computer program were placed over right lobe, left lobe of liver, spleen and cardiac blood pool. Total counts in ROI were divided by the number of pixels in the ROI, and mean count rate per pixels calculated. Mean right-lobe counts were divded by mean-left lobe counts to determine right-to-left hepatic lobe ratio and mean spleen counts were divided by mean liver counts to determine spleen to liver ratio. The results were as follows. 1) Of 424 cases, 292 were male and 132 were female. The majority of age distribution was in $30\sim49$ (54.5%). 2) Inter-observer between two independant operators and inter-method between drawing by light-pen and ROI computer program variations were not significant. 3) The uptake count values (per pixel) determined at each area in normal group were $106.53{\pm}18.35$ in right lobe, $79.00{\pm}13.82$ in left lobe, $17.52{\pm}8.31$ in spleen and $8.09{\pm}3.43$ in cardiac blood pool. 4) In liver cirrhosis, right lobe uptake was decreased but spleen and cardiac blood pool uptakes were increased (p<0.01). 5) Right-to-left hepatic lobe uptake ratio was $1.37{\pm}0.24$ in normal group and significantly low in chronic hepatitis, liver cirrhosis and fatty liver, and more or less low in acute hepatitis. 6) Spleen-to-right hepatic lobe uptake ratio was $0.17{\pm}0.09$ in normal group and high in chronic hepatitis and liver cirrhosis. 7) The computer-quantitation of hepatic and extrahepatic uptake patterns thought to be sensitive and useful method in the interpretation of liver scintigram.

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Atmospheric Dispersion Characteristics of Radioactive Materials according to the Local Weather and Emission Conditions

  • An, Hye Yeon;Kang, Yoon-Hee;Song, Sang-Keun;Kim, Yoo-Keun
    • Journal of Radiation Protection and Research
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    • v.41 no.4
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    • pp.315-327
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    • 2016
  • Background: This study evaluated the atmospheric dispersion of radioactive material according to local weather conditions and emission conditions. Materials and Methods: Local weather conditions were defined as 8 patterns that frequently occur around the Kori Nuclear Power Plant and emission conditions were defined as 6 patterns from a combination of emission rates and the total number of particles of the $^{137}Cs$, using the WRF/HYSPLIT modeling system. Results and Discussion: The highest mean concentration of $^{137}Cs$ occurred at 0900 LST under the ME4_1 (main wind direction: SSW, daily average wind speed: $2.8ms^{-1}$), with a wide region of its high concentration due to the continuous wind changes between 0000 and 0900 LST; under the ME3 (NE, $4.1ms^{-1}$), the highest mean concentration of $^{137}Cs$ occurred at 1500 and 2100 LST with a narrow dispersion along a strong northeasterly wind. In the case of ME4_4 (S, $2.7ms^{-1}$), the highest mean concentration of $^{137}Cs$ occurred at 0300 LST because $^{137}Cs$ stayed around the KNPP under low wind speed and low boundary layer height. As for the emission conditions, EM1_3 and EM2_3 that had the maximum total number of particles showed the widest dispersion of $^{137}Cs$, while its highest mean concentration was estimated under the EM1_1 considering the relatively narrow dispersion and high emission rate. Conclusion: This study showed that even though an area may be located within the same radius around the Kori Nuclear Power Plant, the distribution and levels of $^{137}Cs$ concentration vary according to the change in time and space of weather conditions (the altitude of the atmospheric boundary layer, the horizontal and vertical distribution of the local winds, and the precipitation levels), the topography of the regions where $^{137}Cs$ is dispersed, the emission rate of $^{137}Cs$, and the number of emitted particles.

Interpretation of Migration of Radionuclides in a Rock Fracture Using a Particle Tracking Method (입자추적법을 사용한 암반균열에서 핵종이동 해석)

  • Chung Kyun Park;Pil Soo Hahn;Douglas J. Drew
    • Nuclear Engineering and Technology
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    • v.27 no.2
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    • pp.176-188
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    • 1995
  • A particle tracking scheme was developed in order to model radionuclide transport through a tortuous flow Held in a rock fracture. The particle tacking method may be used effectively in a heterogeneous flow field such as rock fracture. The parallel plate representation of the single fracture fails to recognize the spatial heterogeneity in the fracture aperture and thus seems inadequate in describing fluid movement through a real fracture. The heterogeneous flow field une modeled by a variable aperture channel model after characterizing aperture distribution by a hydraulic test. To support the validation of radionuclide transport models, a radionuclide migration experiment was performed in a natural fracture of granite. $^3$$H_2O$ and $^{131}$ I are used as tracers. Simulated results were in agreement with experimental result and therefore support the validity of the transport model. Residence time distributions display multipeak curves caused by the fast arrival of solutes traveling along preferential fracture channels and by the much slower arrival of solutes following tortous routes through the fracture. Results from the modelling of the transport of nonsorbing tracer through the fracture show that diffusion into the interconnected pore space in the rock mass has a significant effect on retardation.

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Surface Dose Evaluation According to the Environment Around the Patient after Nuclear Medicine Examination (핵의학 검사 후 환자의 주위 환경에 따른 표면 선량 평가)

  • Lee, Young-Hee;Park, Jae-Yoon
    • Journal of the Korean Society of Radiology
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    • v.15 no.7
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    • pp.943-948
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    • 2021
  • The purpose of this study was to investigate changes in surface dose due to increased scattering of gamma rays from patients injected with 99mTc and 18F, which are radioactive isotopes, in close contact with materials with high atomic number such as the walls of the stable room. Prepare 99mTc and 18F by injecting 20 and 10 mCi respectively into the NEMA phantom, and then measuring the surface dose for 60 minutes by positioning the phantom at a height of 1 m above the surface, at a distance of 0, 5 and 10 cm from the wall, and at the same location as the phantom facing the wall. Each experiment was repeated five times for reproducibility of the experiment and one way analysis of variability (ANOVA) was performed for significance testing and Tukey was used as a post-test. The study found that surface doses of 220.268, 287.121, 243.957, and 226.272 mGy were measured at 99mTc, respectively, in the case of empty space and in the case of 0, 5 and 10 cm, while those of 18F were measured at 637.111, 724.469, 657.107, and 640.365 mGy, respectively. In order to reduce changes in surface dose depending on the patient's location while waiting, it is necessary to keep the distance from the ground or the wall where the patient is closely adhered to, or install an air mattress, etc., to prevent the scattered lines as much as possible, considering the scattered lines due to the wall etc. in future setup of the patient waiting room and safety room, and in addition to the examination, the external skin width may be reduced.

A Study on Planning of Korean Convergence Housing Complex's Residential Culture. -Focused on Segwon Jeong's Improved Hanok Planning- (한국형 융합 집합주거문화 계획 연구 -정세권의 개량한옥 계획을 대상으로-)

  • Choi, Ho-Soon
    • Journal of the Korea Convergence Society
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    • v.10 no.4
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    • pp.123-130
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    • 2019
  • The Study aims at carrying out basic research on the future housing culture plan by the aging and low fertility phenomenon which is the most serious problem that Korean society faces today. In the future, the housing culture will be transformed into a 'convergence housing complex's residential culture' that can be coexisted with households with various members, rather than a housing type represented by apartments today, due to the phenomenon of nuclear family and the increase of one resident. In this regard, this study is a basic study on the housing complex culture of Korea. It is not that the hosing complex culture has been imported from the western society today, but the Korean traditional housing complex's culture proposed by Korean first developer Segwon Jeong has already existed in Korea urban and architectural perspective. In the early 20th century, Segwon's improved Hanok planned to complement the disadvantages of the existing hanok and the modernization of hanok such as the standardization of hanok, moreover the most important point is the beginning of the Korean style housing complex by modernization of the inner space of hanok. It is expected that this study for Segwon's housing complex of improved hanok will provide important basic data for the Korean-style convergence residential culture plan needed for our society in the future.

Development of a polystyrene phantom for quality assurance of a Gamma Knife®

  • Yona Choi;Kook Jin Chun;Jungbae Bahng;Sang Hyoun Choi;Gyu Seok Cho;Tae Hoon Kim;Hye Jeong Yang;Yeong Chan Seo;Hyun-Tai Chung
    • Nuclear Engineering and Technology
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    • v.55 no.8
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    • pp.2935-2940
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    • 2023
  • A polystyrene phantom was developed following the guidance of the International Atomic Energy Association (IAEA) for gamma knife (GK) quality assurance. Its performance was assessed by measuring the absorbed dose rate to water and dose distributions. The phantom was made of polystyrene, which has an electron density (1.0156) similar to that of water. The phantom included one outer phantom and four inner phantoms. Two inner phantoms held PTW T31010 and Exradin A16 ion chambers. One inner phantom held a film in the XY plane of the Leksell coordinate system, and another inner phantom held a film in the YZ or ZX planes. The absorbed dose rate to water and beam profiles of the machine-specific reference (msr) field, namely, the 16 mm collimator field of a GK PerfexionTM or IconTM, were measured at seven GK sites. The measured results were compared to those of an IAEA-recommended solid water (SW) phantom. The radius of the polystyrene phantom was determined to be 7.88 cm by converting the electron density of the plastic, considering a water depth of 8 g/cm2. The absorbed dose rates to water measured in both phantoms differed from the treatment planning program by less than 1.1%. Before msr correction, the PTW T31010 dose rates (PTW Freiberg GmbH, New York, NY, USA) in the polystyrene phantom were 0.70 (0.29)% higher on average than those in the SW phantom. The Exradin A16 (Standard Imaging, Middleton, WI, USA) dose rates were 0.76 (0.32)% higher in the polystyrene phantom. After msr correction factors were applied, there were no statistically significant differences in the A16 dose rates measured in the two phantoms; however, the T31010 dose rates were 0.72 (0.29)% higher in the polystyrene phantom. When the full widths at half maximum and penumbras of the msr field were compared, no significant differences between the two phantoms were observed, except for the penumbra in the Y-axis. However, the difference in the penumbra was smaller than variations among different sites. A polystyrene phantom developed for gamma knife dosimetry showed dosimetric performance comparable to that of a commercial SW phantom. In addition to its cost effectiveness, the polystyrene phantom removes air space around the detector. Additional simulations of the msr correction factors of the polystyrene phantom should be performed.