• Title/Summary/Keyword: nuclear export

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Development of Nuclear Industry Information Gathering and Analysis System and Denied Persons Information Gathering System for Preventing Illegitimate Export of Trigger List Items in Korea

  • Sangjun Lee
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.21 no.3
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    • pp.315-327
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    • 2023
  • In South Korea, the exporters of items related to nuclear power generation are diversified. Consequently, there is a risk of illegitimate export by companies failing to recognize the export control system because the awareness about this system for the strategic items among the subcontractors of nuclear power facilities is limited. To prevent illegitimate export of the strategic items, it is necessary to conduct outreach activities regarding the export control system for the related companies. Additionally, the exporters and export license examiners should consider whether an export target is on the Denial List, who may divert the strategic items to weapons of mass destruction. Therefore, the Korea Institute of Nuclear Nonproliferation and Control developed two systems for controlling illegitimate export of the Trigger List items. The first system, Nuclear Industry Information Collection and Analysis System, can gather information about the key nuclear industries in Korea and analyze the dealing of strategic items. The second system, Denied Persons Information Gathering System, can regularly gather information about the denied persons and provide the updated data to the exporters and regulatory examiners. These two systems can be used for outreach activities and export license examination to prevent illegitimate export of the strategic items.

An Analysis on the Trend of International Export control Regimes in Nuclear Industry (원자력산업에서 국제 수출통제 체제에 대한 동향 및 대응방안)

  • Ryu Jae-Su;Lee Byeong-Uk;Yang Maeng-Ho;Lee Han-Myeong
    • Proceedings of the Korea Technology Innovation Society Conference
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    • 2004.05a
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    • pp.203-212
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    • 2004
  • International nuclear export control regimes have been continuously strengthening through revision of guidelines to prevent a horizontal nuclear proliferation. Recently, they have been trying to include sensitive technologies, information exchange on export permission and supply conditions to their guidelines. Therefore, this study analyzes current issues of the amended guidelines within international export control regimes and proposes a proper solution to effectively implement the national regulation.

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UAP56- a key player with surprisingly diverse roles in pre-mRNA splicing and nuclear export

  • Shen, Hai-Hong
    • BMB Reports
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    • v.42 no.4
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    • pp.185-188
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    • 2009
  • Transcripts contain introns that are usually removed from premessenger RNA (MRNA) in the process of pre-mRNA splicing. After splicing, the mature RNA is exported from the nucleus to the cytoplasm. The splicing and export processes are coupled. UAP56 protein, which is ubiquitously present in organisms from yeasts to humans, is a DExD/H-box family RNA helicase that is an essential splicing factor with various functions in the prespliceosome assembly and mature spliceosome assembly. Collective evidence indicates that UAP56 has an essential role in mRNA nuclear export. This mini-review summarizes recent evidence for the role of UAP56 in pre-mRNA splicing and nuclear export.

Phosphorylation of p53 at threonine 155 is required for Jab1-mediated nuclear export of p53

  • Lee, Eun-Woo;Oh, Wonkyung;Song, Hosung Paul;Kim, Won Kon
    • BMB Reports
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    • v.50 no.7
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    • pp.373-378
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    • 2017
  • The Jun activation-domain binding protein 1 (Jab1) induces p53 nuclear export and cytoplasmic degradation, but the underlying mechanism is poorly understood. Here, we show that phosphorylation at the threonine 155 residue is essential for Jab1-mediated p53 nuclear export. Jab1 stimulated phosphorylation of p53 at T155 was inhibited by curcumin, an inhibitor of COP9 signalosome (CSN)-associated kinases. The T155E mutant, which mimics phosphorylated p53, exhibited spontaneous cytoplasmic localization in the absence of Jab1. This process was prevented by leptinomycin B (LMB), but not by curcumin. The substitution of threonine 155 for valine (T155V) abrogated Jab1-mediated p53 nuclear export, indicating that phosphorylation at this site is essential for Jab1-mediated regulation of p53. Although T155E can be localized in the cytoplasm in the absence of Mdm2, the translocation of T155E was significantly enhanced by ectopic Hdm2 expression. Our data suggests that Jab1-mediated phosphorylation of p53 at Thr155 residue mediates nuclear export of p53.

Effect of Trade with China on North Korean Economic growth: Focus on Liaoning (중국과의 무역이 북한 경제성장률에 미치는 영향: 랴오닝성을 중심으로)

  • Ting, Fan Xiao;Kim, Young-Min
    • Asia-Pacific Journal of Business
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    • v.13 no.3
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    • pp.463-473
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    • 2022
  • Purpose - The purpose of this study is to examine the effect of the North Korea's net export to China and Liaoning on the North Korean economic growth. Design/methodology/approach - This study collects the data on the net export of North Korea to China and Liaoing from General Administration of Customs, People's Republic of China. Vector Autoregression(VAR) is also employed for the analysis. Findings - First, North Korea's net export to all of China and Liaoning gives the positive effect on North Korean economic growth. Second, the nuclear test of North Korea gives the negative effect on the North Korean economic growth. Third, the net export to China and Liaoning granger causes the North Korean economic growth. Lastly, the nuclear test of North Korea also granger causes the North Korean economic growth. Research implications or Originality - The estimation results show the net export of North Korea to China as well as Liaoning is important to the economic growth. Therefore, we need to examine North Korea's trades with specific region as well as all of China in order to enhance the North Korean economic growth.

Synthetic Lethal Mutations with spmex67 of Schizosaccharomyces pombe in the Mediation of mRNA Export

  • Yoon, Jin-Ho
    • Journal of Microbiology
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    • v.41 no.2
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    • pp.115-120
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    • 2003
  • Mex67p/Tap are evolutionally conserved mRNA export factors. To identify mutations in genes that are functionally linked to mex67 with respect to mRNA export, we used a synthetic lethal genetic screen in Schizosaccharomyces pombe. Three synthetic lethal mutants were isolated and mutations in these mutants defined separate complementation groups. These mutants exhibited the accumulation of poly A$\^$+/ RNA in the nucleus, with a decrease in the cytoplasm under synthetically lethal conditions, suggesting that the mutations cause an mRNA nuclear export defect. In addition, the S. pombe genes that were found to be involved in mRNA export did not suppress the synthetic lethality of these mutants. These results indicate that the isolated mutants contain mutations in new genes, which are involved in mRNA export from the nucleus.