• IEMEK Journal of Embedded Systems and Applications
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• v.10 no.4
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• pp.207-212
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• 2015

Wi-Fi Direct allows battery powered mobile devices to form a wireless ad hoc network. Since one member of the network called Group Owner (GO) takes the role of managing the network, the network lifetime is mainly affected by the energy efficiency of GO. Hence, Wi-Fi Direct defines power saving schemes that allow GO to save the energy by turning off its radio interface during the periods called absence periods. However, the Wi-Fi Direct specification does not specify how to set parameters (denoted by PS parameters) determining the schedule of the absence periods. In this paper, we therefore propose a novel traffic-aware power saving scheme for Wi-Fi Direct networks. In particular, the proposed scheme estimates the application-level traffic load and adaptively tunes the PS parameters according to the estimated value.

• Biomedical Science Letters
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• v.10 no.1
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• pp.15-21
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• 2004

Vitamin $D_3$ up-regulated protein 1 (VDUP1) gene is known to be a novel member of early response genes as an oxidative stress mediator. To elucidate role of VDUP1 expression in neuronal injury, VDUP1 gene expression and histological change were tested in the spinal cords after traumatic spinal cord injury (SCI) in young and adult rats. VDUP1 transcript was detected weakly in a few cells in the spinal cords of control young and adult rats. VDUP1 transcript was increased in the contused spinal cords 1 day after SCI in both young and adult rats. VDUP1 transcript was decreased in the spinal cords 7 days after SCI in young rats. However, VDUP1 transcript was not decrease significantly 7 days in the spinal cords after SCI in adult rats. Cell damage in the spinal cords and hind limb dysfunction were more prominent 7 days after SCI in adult rats compared with that in young rats. These data show that VDUP1 may be involved in neurodegeneration after traumatic SCI.

• Journal of Microbiology and Biotechnology
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• v.28 no.9
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• pp.1536-1541
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• 2018

A yellowish, flexirubin-pigment-producing strain $I3-3^T$ was isolated from river water in Iksan, the Republic of Korea. The strain was gram-negative, aerobic, non-motile, showed catalase and oxidase activities, and could grow at a temperature range of $10-35^{\circ}C$, pH 5.0-10 and 0-2.0% (w/v) of NaCl. The major fatty acids were iso-$C_{15:0}$, iso-$C_{17:0}$ 3-OH and summed feature 3 (comprising $C_{16:1}{\omega}7c$ and/or $C_{16:1}{\omega}6c$). The isolate contained phosphatidylethanolamine, one aminolipid, and two unidentified lipids as the major polar lipids. Menaquinone-6 (MK6) was the major respiratory quinone. The G+C content of the genomic DNA of strain $I3-3^T$ was 35.6%. Comparison of the 16S rRNA gene sequence with the sequences of the closely related type strains showed highest sequence similarity of 96.95% and 96.93% to Flavobacterium nitrogenifigens $NXU-44^T$ and Flavobacterium compostarboris $15C3^T$, respectively. Based on phenotypic and phylogenetic distinctiveness, strain $I3-3^T$ is considered as a member of novel species within the genus Flavobacterium, for which Flavobacterium amnigenum sp. nov. is proposed. The type strain is $I3-3^T$ (=KCTC $52884^T$ =NBRC $112871^T$).

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.11 no.12
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• pp.5729-5744
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• 2017

Vehicular Ad Hoc Networks (VANET) in the large-scale road section usually have typical characteristics of large number of vehicles and unevenly distribution over geographic spaces. These two inherent characteristics lead to the unsatisfactory performance of VANETs. This poor performance is mainly due to fragile communication link and low dissemination efficiency. We propose a novel routing mechanism to address the issue in the paper, which includes a competition-based routing discovery with priority metrics and a local routing repair strategy. In the routing discovery stage, the algorithm uses adaptive scheme to select a stable route by the priorities of routing metrics, which are the length of each hop, as well as the residual lifetime of each link. Comparisons of different ratios over link length and link stability further show outstanding improvements. In the routing repair process, upstream and downstream nodes also compete for the right to establish repair process and to remain as a member of the active route after repair. Our simulation results confirm the improved performance of the proposed algorithm.

• Steel and Composite Structures
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• v.21 no.4
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• pp.805-827
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• 2016

A new type of precast CFST column to RC beam braced frame is proposed in this paper. A series of shake table tests were conducted to excite a one-third scale six-story model for investigating the global seismic performance of this type of structure against earthquake actions. Particular emphasis was given to its dynamic property, global seismic responses and failure path. Correspondingly, a numerical model built on the basis of fiber-beam-element model, multi-layer shell model and element-deactivation method was developed to simulate the seismic performance of the prototype structure. Numerical results were compared with the measured values from shake table tests to verify the validity and reliability of the numerical model. The results demonstrated that the proposed novel precast CFST column to RC beam braced frame performs excellently under strong earthquake excitations; the "strong CFST column-weak RC beam" and "strong connection-weak member" anti-seismic design principles can be easily achieved; the maximum deflections of precast CFSTC-RCB braced frame satisfied the deflection limitations proposed in national code; the numerical model can properly simulate the dynamic property and responses of the precast CFSTC-RCB braced frame that are highly concerned in engineering practice.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3899-3903
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• 2012

B7-H3 is a newly discovered member of the B7/CD28 superfamily which functions as an important T-cell immune molecule. It has been reported recently that B7-H3 is highly expressed in many cancer cells, the data indicating that it may be a regulation factor contributing to tumor-resistance. In our study, we used bioinformatics to identify differentially expressed genes between colonic cancer cells and normal colonic cells, aiming to analyze mechanisms and identify sub-pathways closely related to progression, with the final aim of finding small molecule drugs which might interfere this progression. We found that ajmaline is one related factor which may enhance self-immunity in colon carcinoma therapy and B7-H3 plays important roles with regard to immunoreactions of colonic cancer cells. All the results indicate that H7-B3 is a favorable prognostic biomarker for colon carcinomas, providing novel information regarding likely targets for intervention.

• Korean Journal of Veterinary Research
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• v.50 no.2
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• pp.79-84
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• 2010

The molecule possessing ankyrin-repeats induced by lipopolysaccharide (MAIL) protein is a novel member of the $Ikappa{\beta}$ family. In the present study, we examined the effect of norepinephrine (NE) on MAIL mRNA expression in primary cultured mouse hepatocytes and non-parenchymal liver cells. MAIL mRNA expression in hepatocytes and non-parenchymal liver cells was not directly influenced by NE. However, MAIL mRNA expression in hepatocytes was significantly induced by incubation with a culture medium of non-parenchymal liver cells, treated with NE. Pretreatment with an interleukin (IL)-1 receptor antagonist significantly attenuated the stimulatory effect of the medium. Moreover, exogenous $IL-1{\beta}$ induced MAIL mRNA expression in hepatocytes, while IL-6 and tumor necrosis factor $\alpha$ did not. The concentration of $IL-1{\beta}$ in the medium of non-parenchymal liver cells was significantly increased after NE-treatment. These results suggest that NE can induce MAIL mRNA expression in hepatocytes through $IL-1{\beta}$, released from non-parenchymal liver cells.

• BMB Reports
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• v.41 no.6
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• pp.479-484
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• 2008

In the present study, we demonstrate that ephrin-A5 is able to induce a transient increase of MAP kinase activity in PC12 cells. However, the effects of ephrin-A5 on the MAP kinase signaling pathway are about three-fold less than that of EGF. In addition, we demonstrate that EphA4 is the only Eph member expressed in PC12 cells, and that tyrosine phosphorylation induced by ephrin-A5 treatment is consistent with the magnitude and longevity of MAP kinase activation. Experiments using the Ras dominant negative mutant N17Ras reveal that Ras plays a pivotal role in ephrin-A5-induced MAP kinase activation in PC12 cells. Importantly, we found that the EphA4 receptor is rapidly internalized by endocytosis upon engagement of ephrin-A5, leading to a subsequent reduction in the MAP kinase activation. Together, these data suggest a novel regulatory mechanism of differential Ras-MAP kinase signaling kineticsexhibited by the forward signaling of EphA4 in PC12 cells.

• Steel and Composite Structures
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• v.26 no.1
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• pp.31-44
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• 2018

This paper reports a novel steel beam-to-column connection suitable for use in the weak axis of I-section column. Monotonic and cyclic loading experimental investigations and numerical analysis of the proposed weak-axis connection were conducted, and the calculation procedure of the beam-column relative rotation angle and plastic rotation angle was developed and described in details. A comparative analysis of mechanical property and steel consumption were employed for the proposed I-section column weak-axis connection and box-section column bending connection. The result showed that no signs of fracturing were observed and the plastic hinge formed reliably in the beam section away from the skin plate under the beam end monotonic loading, and the plastic hinge formed much closer to the skin plate under the beam end cyclic loading. The fracture of welds between diaphragm and skin plate would cause an unstable hysteretic response under the column top horizontal cyclic loading. The proposed weak-axis connection system could not only simplify the design calculation progress when I-section column is adopted in frame structural design but also effectively satisfy the requirements of 'strong joint and weak member', as well as lower steel consumption.

• Fisheries and Aquatic Sciences
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• v.10 no.2
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• pp.60-67
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• 2007

Myostatin (MSTN; also known as GDF8) is a member of the transforming growth factor ${\beta}-superfamily$ of proteins. MSTN negatively regulates mammalian skeletal muscle growth and development by inhibiting myoblast proliferation. Mice and cattle possessing mutant MSTN alleles display a 'double muscling' phenotype characterized by extreme skeletal muscle hypertrophy and/or hyperplasia. We isolated the full-length cDNA of a novel MSTN gene from S. schlegeli muscle tissue and examined its expression pattern in various tissues. The full-length gene (GenBank DQ423474) consists of 1941bp with an open reading frame of 1134 bp, encoding 377 amino acids that show 62-92% amino acid similarity to other vertebrate MSTNs. The predicted protein contains a conserved proteolytic cleavage site (RXRR) and nine conserved cysteine residues at the C terminus. RT-PCR revealed that the unprocessed and prodomain myostatin mRNAs were predominantly present in muscle, with limited expression in other tissues. However, the mature myostatin mRNA was highly expressed in brain and muscle, intermediately expressed in the gills, intestine, heart, and kidney, and weakly expressed in the liver and spleen.