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Acceptability of Low Intensity Anticoagulation Therapy after Mechanical Heart Valve Replacement (기계식 인공 심장판막 치환술 후 낮은 강도 항응혈 관리의 적정성에 관한 연구)

  • Kim, Jong-Woo;Rhie, Sang-Ho;Kim, Young-Chun;Yang, Jun-Ho;Jang, In-Seok;Choi, Jun-Young
    • Journal of Chest Surgery
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    • v.42 no.2
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    • pp.193-200
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    • 2009
  • Background: The long-term administration of oral anticoagulant to the patients with a mechanical heart valve prosthesis is mandatory. However, the appropriate intensity of oral anticoagulant therapy to prevent thromboembolic or hemorrhagic complications is still controversial. We tried to apply low intensity anticoagulant therapy for which the International Normalized Ratios ranged between 1.5 and 2.5, and we analyzed the anticoagulation-related long term outcomes. Material and Method: From January 1992 to December 2002, 144 patients who underwent a single cardiac valve replacement were included in the study, and their ages ranged from 15 to 72 years (mean age: $47.4{\pm}15.1$): there were 49 aortic valve replacements (AVR) and 95 mitral valve replacements (AVR). The patients were followed up monthly or bi-monthly at the outpatient clinic with clinical examinations and measuring the prothrombin time to adjust the International Normalized Ratios (INRs) within the low-intensity target range between 1.5 and 2.5. Result: The follow-up period was 835.3 patient-years (mean: $5.9{\pm}3.5$) and the INRs of 7,706 measurements were available for evaluation. The mean INRs of the aortic and the mitral valve replacement groups were significantly different (p<0.01). All the patients' INRs were within the target range in 61.9% of the measurements. The mean INRs $(2.16{\pm}0.23)$ of the patients with atrial fibrillation, which was found in 30.3% of the patients, were definitely higher than those $(2.03{\pm}0.27)$ measured in the patients with regular rhythm (p<0.01). Thromboembolic episodes occurred in 9 patients with an incidence of 1.08%/patient-year. Major bleeding occurred in 2 patients (MVR) with an incidence of 0.24%/patient-year. The patients who displayed better compliance showed a lower incidence of complications (p=0.000). Conclusion: The anticoagulation therapy with a low-intensity target range after MVR or AVR seems to be effective and feasible, and increasing the patients’ compliance should be done for achieving more effective anticoagulation therapy.

A Study on Temperature Characteristics of Various Depth using Infrared Thermography (적외선 열화상기법을 이용한 균열 깊이에 따른 온도특성에 관한 연구)

  • Jung, Ju-Yeong;Yoon, Hyuk-Jin;Cho, Hyun-Woo;Yang, Hui-Seung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.3
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    • pp.83-89
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    • 2018
  • The thermal characteristics of concrete specimens were analyzed using cement paste specimens with artificial cracks. In order to understand the temperature characteristics of the specimen depending on the crack depth, the specimen was heated and the minimum temperatures of the specimens at which cracks appear were investigated according to the crack depth. It was confirmed that the surface temperature distribution of the specimen varies depending on whether the specimen is cracked or not, because of the single and multiple reflections of the incident energy. Furthermore, as the temperature distribution of the specimen reaches a steady state, the temperature data tends to decrease with the crack depth. Through the observation of the normalized temperatures, it was found that the temperature of the specimens obtained from this experiment reached a steady state after 10 minutes. At this time, the standard deviation of the normalized temperature is around 0.01 or less, and the temperature decreases linearly with increasing crack depth. This result is considered to be closely related to the area where multiple reflections occur in the cracked region. If the correlation between the crack region and the incident energy is analyzed for various specimens, it can be applied to the diffuse reflection of the light.

The Effects of distilled Wild Ginseng Herbal Acupuncture on the Heart Rate Variability(HRV) (산삼 약침이 정상인의 심박변이도(HRV)에 미치는 영향)

  • Roh, Jeong-Du;Kim, Lak-Hyung;Song, Beom-Yong;Yook, Tae-Han
    • Journal of Pharmacopuncture
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    • v.11 no.1
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    • pp.55-69
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    • 2008
  • Objective : We investigated the effects of distilled Wild Ginseng Herbal Acupuncture on autonomic nervous system with the Heart Rate Variability(HRV) in adult man. as well as we tried to observe how distilled Wild Ginseng Herbal Acupuncture on the balance of the autonomic nervous system. Method : We investigated the effects of distilled Wild Ginseng Herbal Acupuncture on autonomic nervous system with the Heart Rate Variability(HRV) in adult man. as well as we tried to observe how distilled Wild Ginseng Herbal Acupuncture on the balance of the autonomic nervous system. 1 healthy volunteers consisted of 31 subjects in experiment(distilled Wild Ginseng Herbal Acupuncture) group and 30 subjects in control(Normal Saline) group. Study form was a randomized, placebo-controlled, double-blind clinical trial. 31 subjects in experiment group were injected distilled Wild Ginseng Herbal Acupuncture at $GB_{21}$(Kyonjong) and 30 subjects in control group were injected Normal Saline at $GB_{21}$(Kyonjong). except of 2 subjects(in control group) who can't be measured and 11 subjects(7 in experiment group and 4 in control group) who move or make unforceable error during measuring. Finally 24 subject in experiment group and 24 subject in control group are studied. We measured HRV by PolyG-I on 7 times : before and after injection per 5 minutes during 30 minutes. The SPSS 10.0 for windows was used to analyze the data and the paired t-test(in group) and Student t-test(between two groups) were used to verify the result. Result : 1. After distilled Wild Ginseng Herbal Acupuncture injection, Mean HRV is significantly low only for first 5 minute, SDNN is significantly high after 5 minute, Complexity is significantly low after 5 minute, HRV index is significantly high after 10 minute and pNN50 is significantly low after 5 minute. 2. SDNN of distilled Wild Ginseng Herbal Acupuncture Group significantly increased from 20minute to 25minute, and pNN50 of distilled Wild Ginseng Herbal Acupuncture Group significantly decreased from 10minute to 15minute and 20 minute to 30 minute compared with those of Normal Saline group. 3. After distilled Wild Ginseng Herbal Acupuncture injection, Ln(TP), Ln(VLF) and Ln(LF) are significantly high after 5 minute, normalized LF is significantly high after 5 minute and normalized HF is significantly low after 5 minute. 4. Ln(TP) and Ln(VLF) of distilled Wild Ginseng Herbal Acupuncture Group significantly increased from 20minute to 25 minute compared with those of Normal Saline group. Conclusion : The results suggest that distilled Wild Ginseng Herbal Acupuncture in healthy adult man tend to activate the autonomic nervous system and sympathetic nervous system compared to Normal Saline within normal range.

Agricultural drought monitoring using the satellite-based vegetation index (위성기반의 식생지수를 활용한 농업적 가뭄감시)

  • Baek, Seul-Gi;Jang, Ho-Won;Kim, Jong-Suk;Lee, Joo-Heon
    • Journal of Korea Water Resources Association
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    • v.49 no.4
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    • pp.305-314
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    • 2016
  • In this study, a quantitative assessment was carried out in order to identify the agricultural drought in time and space using the Terra MODIS remote sensing data for the agricultural drought. The Normalized Difference Vegetation Index (NDVI) and Enhanced Vegetation Index (EVI) were selected by MOD13A3 image which shows the changes in vegetation conditions. The land cover classification was made to show only vegetation excluding water and urbanized areas in order to collect the land information efficiently by Type1 of MCD12Q1 images. NDVI and EVI index calculated using land cover classification indicates the strong seasonal tendency. Therefore, standardized Vegetation Stress Index Anomaly (VSIA) of EVI were used to estimated the medium-scale regions in Korea during the extreme drought year 2001. In addition, the agricultural drought damages were investigated in the country's past, and it was calculated based on the Standardized Precipitation Index (SPI) using the data of the ground stations. The VSIA were compared with SPI based on historical drought in Korea and application for drought assessment was made by temporal and spatial correlation analysis to diagnose the properties of agricultural droughts in Korea.

Effects of Hip Internal Rotation on Knee Extensor and Hip Abductor Electromyographic Activity During Stair Up and Down (계단 오르고 내리기시 엉덩관절 내회전이 무릎관절 폄근과 엉덩관절 벌림근 근활성도에 미치는 영향)

  • Oh, Jae-Seap;Kwan, Oh-Yun;Yi, Chung-Hwi;Jean, Hye-Sean
    • Physical Therapy Korea
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    • v.15 no.2
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    • pp.54-63
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    • 2008
  • The purpose of this study was to examine the effect of the hip internal rotation on knee extensor and hip abductor electromyographic (EMG) activity during stair up and stair down mobility. Eighteen healthy subjects were recruited. All subjects performed stair up and down movements on a step of 30cm height while maintaining the hip in neutral (condition 1) and hip in internal rotation (condition 2). Surface EMG activity was recorded from five muscles (gluteus maximus, vastus lateralis (VL), vastus medialis oblique (VMO), posterior gluteus medius (Gmed), and tensor fascia latae (TFU)) and hip internal rotation angle was measured using a three dimensional motion analysis system The time period for stair up and down was normalized using the MatLab 6.5 program, and EMG activity was normalized to the value of maximal voluntary isometric contraction (%MVIC). The EMG activities according to the hip rotation (neutral or internal rotation) during the entire time period of stair up and down in each phase were compared using a paired t-test. During the entire period of stair up, the EMG activities of VL and TFL in condition 2 were significantly greater than in condition 1 (p<.05). During the entire period of stair down, the EMG activities of VL and TFL in condition 2 were significantly greater than in condition 1 (p<.05). However, the EMG activities of the other muscles were not significantly different between the conditions (p>.05). These results suggest that the stair up and down maintaining hip internal rotation was could be a contributing factor on patellar lateral tracking.

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Effects of Bias Voltage and Ion-incident Angle on the Etching of Photoresist in a High-density CHF3 Plasma (고밀도 CHF3 플라즈마에서 바이어스 전압과 이온의 입사각이 Photoresist의 식각에 미치는 영향)

  • Kang, Se-Koo;Min, Jae-Ho;Lee, Jin-Kwan;Moon, Sang Heup
    • Korean Chemical Engineering Research
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    • v.44 no.5
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    • pp.498-504
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    • 2006
  • The etch rates of photoresist (PR) and the etch selectivity of $SiO_2$ to PR in a high density $CHF_3$ plasma were investigated at different ion-incident angles and bias voltages. A Faraday cage was employed for the accurate control of ion-incident angles. The ion energy was controlled by changing bias voltages. The etch rate of $SiO_2$ continuously decreased with ion-incident angles but the etch rate of PR remained constant up to the middle angle region and decreased afterwards. The etch rates of $SiO_2$ normalized to those at $0^{\circ}$ incident angle changed with the ion-incident angle following a cosine(${\theta}$) curve. On the other hand, the normalized etch rates of the PR changed showing a drastic over-cosine shape in the middle angle region. The etch selectivity of $SiO_2$ to PR decreased with an increase in the ion-incident angle because the etch yields of PR were enhanced by physical sputtering in the middle angle region compared to the case of $SiO_2$ etching. The etch selectivity of $SiO_2$ to PR decreased with an increase in the bias voltage at nearly all ion-incident angles.

Accuracy Assessment of Unsupervised Change Detection Using Automated Threshold Selection Algorithms and KOMPSAT-3A (자동 임계값 추출 알고리즘과 KOMPSAT-3A를 활용한 무감독 변화탐지의 정확도 평가)

  • Lee, Seung-Min;Jeong, Jong-Chul
    • Korean Journal of Remote Sensing
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    • v.36 no.5_2
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    • pp.975-988
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    • 2020
  • Change detection is the process of identifying changes by observing the multi-temporal images at different times, and it is an important technique in remote sensing using satellite images. Among the change detection methods, the unsupervised change detection technique has the advantage of extracting rapidly the change area as a binary image. However, it is difficult to understand the changing pattern of land cover in binary images. This study used grid points generated from seamless digital map to evaluate the satellite image change detection results. The land cover change results were extracted using multi-temporal KOMPSAT-3A (K3A) data taken by Gimje Free Trade Zone and change detection algorithm used Spectral Angle Mapper (SAM). Change detection results were presented as binary images using the methods Otsu, Kittler, Kapur, and Tsai among the automated threshold selection algorithms. To consider the seasonal change of vegetation in the change detection process, we used the threshold of Differenced Normalized Difference Vegetation Index (dNDVI) through the probability density function. The experimental results showed the accuracy of the Otsu and Kapur was the highest at 58.16%, and the accuracy improved to 85.47% when the seasonal effects were removed through dNDVI. The algorithm generated based on this research is considered to be an effective method for accuracy assessment and identifying changes pattern when applied to unsupervised change detection.

Traffic Sign Recognition using SVM and Decision Tree for Poor Driving Environment (SVM과 의사결정트리를 이용한 열악한 환경에서의 교통표지판 인식 알고리즘)

  • Jo, Young-Bae;Na, Won-Seob;Eom, Sung-Je;Jeong, Yong-Jin
    • Journal of IKEEE
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    • v.18 no.4
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    • pp.485-494
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    • 2014
  • Traffic Sign Recognition(TSR) is an important element in an Advanced Driver Assistance System(ADAS). However, many studies related to TSR approaches only in normal daytime environment because a sign's unique color doesn't appear in poor environment such as night time, snow, rain or fog. In this paper, we propose a new TSR algorithm based on machine learning for daytime as well as poor environment. In poor environment, traditional methods which use RGB color region doesn't show good performance. So we extracted sign characteristics using HoG extraction, and detected signs using a Support Vector Machine(SVM). The detected sign is recognized by a decision tree based on 25 reference points in a Normalized RGB system. The detection rate of the proposed system is 96.4% and the recognition rate is 94% when applied in poor environment. The testing was performed on an Intel i5 processor at 3.4 GHz using Full HD resolution images. As a result, the proposed algorithm shows that machine learning based detection and recognition methods can efficiently be used for TSR algorithm even in poor driving environment.

Effects of Different Mycotoxin Adsorbents on Performance, Meat Characteristics and Blood Profiles of Avian Broilers Fed Mold Contaminated Corn

  • Wang, R.J.;Fui, S.X.;Miao, C.H.;Feng, D.Y.
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.1
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    • pp.72-79
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    • 2006
  • 1,225 healthy day-old avian broiler chicks were used to investigate the effects of activated charcoal (AC, made from willow tree), hydrated sodium calcium aluminosilicates (HSCAS) and esterified glucomannan (EGM) supplementation on broiler performance, blood profiles and meat characteristics when less moldy or moldy corn was included to formulate seven isocaloric and isonitrogenous diets: Positive Control (less moldy corn diet, PC), PC+2% AC, Negative Control (moldy corn, NC), NC+0.05% EGM, NC+0.1% EGM, NC+0.5% HSCAS and NC+1% AC. PC+2% AC resulted in lower growth rate, poorer feed conversion ratio (FCR), more leg problems and higher mortality of birds than those fed PC diet (p<0.05). Inclusion of 0.05% EGM, 0.1% EGM, 0.5% HSCAS and 1% AC in NC diet did not improve average daily weight gain (ADG) or affect feed intake of birds during the first or the second three-week periods. However, 0.05% EGM tended to (p>0.05) and 0.1% EGM significantly (p<0.05) improved FCR during the first three-week period. Breast meat of NC birds had higher Minolta $L^*$ values (white) but lower $a^*$ (reddish) and $b^*$ (yellowish) values (p<0.01) than the PC birds. Addition of 0.05% EGM and 0.1% EGM in NC diet reduced the $L^*$ values (p<0.05), improved $a^*$ and $b^*$ values (p<0.05) of breast meat of birds fed NC diet, but had no effect on meat color when 0.5% HSCAS or 1% AC was included (p>0.05). Relative weight of liver to body was reduced by feeding NC diet (p<0.05) and could not be normalized by different mycotoxin adsorbents (p>0.05) to the ratio of the PC birds. Relative weight of cholecyst of NC birds was increased compared with PC birds and could only be normalized by addition of 0.05% EGM and 1% AC (p<0.05) in NC diet. NC birds had lower serum albumin level than the PC birds (p<0.05) and addition of 0.05% EGM or 1% AC in NC diet did normalize serum albumin level. Addition of 0.5% HSCAS in NC diet further reduced serum albumin, globulin, total protein and uric acid levels (p<0.05). It was concluded that lower FCR during the first three-week period of growth and deterioration of meat quality observed in bird fed moldy corn with moderate T2 and fuminisin contamination and damaged nutrients and pigment availability, might be improved by dietary supplementation of 0.05% to 0.1% EGM, but not by 1% AC or 0.5% HSCAS supplementation.

A Role of Standard Material in Rare Earth Element Analysis by ICP-MS (ICP-MS를 이용한 희토류원소 분석시 표준시료의 선택이 미치는 영향)

  • Lee Seung-Gu;Kim Kun-Han;Song Yong Sun;Kim Yongje
    • The Journal of the Petrological Society of Korea
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    • v.14 no.4 s.42
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    • pp.237-250
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    • 2005
  • In order to clarify the effect of standard rock material in the chemical analysis of rare earth element abundance with ICP-MS, we measured rare earth element abundance of KIGAM granite standard rock material (KG-1), USGS granite standard rock material (G-2), GSJ granite standard rock materials (JG-1a and JG-2). In REE analysis, we used conventional calibration standard solutions, KG-1, JG-1a, JG-2 and G-2 as standard material, respectively. Chondrite-normalized LREE patterns of low granite standard material correspond well each other in the recommended value and the estimated value regardless of a kind of standard rock. However, the HREE patterns of the estimated value based on G-2 or JG-2 and the recommended value are different from each other. Such difference may be due to the wrong recommended value or a specific geochemical properly of the standard rock material itself, The chondrite-normalized REE patterns of four standard rock materials estimated on the basis of KG-1 or JG-1 a show little deviation compared to the those of the recommended values. This suggests that KG-1 and JG-1a may be a optimum standard material for granitoids.