• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.5
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• pp.679-686
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• 2012

This study was to elucidate the effects of Ukgan-san on the hyperthyroidism induced by sodium levothyroxine. Hyperthyroidisms were induced by continuous subcutaneous treatment of LT4, 0.3 mg/kg, once a day for 27days, and 1,500, 1,000 and 500 mg/kg of Ulkansan extracts were orally administered, once a day for 15 days from 12th LT4 treatment, and the changes on the body, thyroid gland, liver and epididymal fat pad weights, serum triiodothyronine(T3), thyroxine(T4), thyroid-stimulating hormone(TSH), asparte aminotransferase (AST) and alanine aminotransferase (ALT) concentrations, hepatic lipid peroxidation(LPO), glutathione(GSH), superoxide dismutase(SOD) and catalase(CAT) activities were investigated with throid gland, liver and epididymal fat pad histopathological changes. The effects of Ukan-san extracts were compared with that of propyl thiouracil(PTU), a standard antithyroidic drug 10 mg/kg(intraperitoneally). 1,500 and 1,000 mg/kg of Ukan-san extracts reversed all LT4-induced hyperthyroidisms and these effects indicating their potential in the regulation of hyperthyroidism. Further, the Ukan-san extract normalized LT4-induced liver oxidative stresses, and also reduced liver damages and epididymal fat pad reducements suggesting its antioxidative and relative organ protective nature. However, nor favorable effects on LT4-induced hyperthyroidisms were detected in Ulkansan 500 mg/kg treated rats as compared with LT4 control rats in the present study. These effects of Ukan-san may help improvement of hyperthyroidisms and accompanied various organ damages.

• Tribology and Lubricants
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• v.30 no.5
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• pp.284-290
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• 2014

The influence of round embossed surface on slider bearing characteristics and its load carrying capacity is discussed for thin film effect of embossed slider bearing. For the numerical computation of lubrication parameters such as pressure, load capacity and shear stress that are normalized and a Reynolds equation is used for the analysis of embossed slider bearing characteristics. For this purpose, the finite difference method of central difference scheme is used in this study. In a slider bearing with embossed form, several simulation parameters such as pressure, load capacity and shear stress of the bearing can be obtained according to independent parameters such as the slope of the slider bearing and number of embossing in the upper slider. Also this results can be summarized and be stored in sequential data file for latter analysis. After all, their distribution of the pressure and shear stress parameters can be displayed and be analyzed easily by using the developed program with matlab GUI technique. The independent parameters such as a number of embossing and a slope of the embossed surface slider are used for discussing simulation parameters of pressure distribution, shear stress and load carrying capacity of the round embossing. These study results reported in this paper should be applied to the other shaped slider bearing with a rectangular embossed surface or rectangular waved surface.

• BMB Reports
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• v.37 no.5
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• pp.533-537
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• 2004

Previously published kinetic data on the interactions of seventeen different enzymes with their physiological substrates are re-examined in order to understand the connection between ground state binding energy and transition state stabilization of the enzyme-catalyzed reactions. When the substrate ground state binding energies are normalized by the substrate molar volumes, binding of the substrate to the enzyme active site may be thought of as an energy concentration interaction; that is, binding of the substrate ground state brings in a certain concentration of energy. When kinetic data of the enzyme/substrate interactions are analyzed from this point of view, the following relationships are discovered: 1) smaller substrates possess more binding energy concentrations than do larger substrates with the effect dropping off exponentially, 2) larger enzymes (relative to substrate size) bind both the ground and transition states more tightly than smaller enzymes, and 3) high substrate ground state binding energy concentration is associated with greater reaction transition state stabilization. It is proposed that these observations are inconsistent with the conventional (Haldane) view of enzyme catalysis and are better reconciled with the shifting specificity model for enzyme catalysis.

• Journal of Advanced Navigation Technology
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• v.18 no.1
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• pp.78-83
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• 2014

In this paper, the solutions of TM (transverse magnetic) scattering problems by perfectly conducting strip grating on two dielectric layers are analyzed by applying the FGMM (Fourier Galerkin moment method) as a numerical method. For the TM scattering problem, the induced surface current density is expected to the very high value at both edges of the strip, then the induced surface current density on the strip is expanded in a series of the multiplication of the functions of appropriate edge boundary condition and the Chebyshev polynomials of the first kind. The numerical results are obtained for the magnitude of induced current density, the normalized reflected power and transmitted power. The numerical results using proposed functions were improved the convergence faster than existing exponential functions, and the numerical results shown the good agreement compared to those of the existing papers.

• Journal of Advanced Navigation Technology
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• v.11 no.2
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• pp.196-202
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• 2007

In this paper, The TE(transverse electric) scattering problems by a resistive strip grating over a grounded dielectric plane with edge boundary condition are analyzed by applying the FGMM(Fourier-Galerkin Moment Method) known as a numerical procedure. For a TE scattering problem, the induced surface current density is expected to the zero value at both edges of the resistive strip, then the induced surface current density on the resistive strip is expanded in a series of the multiplication of Gegenbauer(Ultraspherical) polynomials with the first order and functions of appropriate edge boundary condition. To verify the validity of the proposed method, the numerical results of normalized reflected power for the uniform resistivity R = 100 ohms/square and R = 0 as a conductive strip case show in good agreement with those in the existing papers.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.21 no.12
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• pp.1710-1719
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• 1997

An approximate analytical solution for the initial transient process of close-contact melting occurring between a phase change material kept at its melting temperature and an isothermally heated flat surface is derived. The model is so developed that it can cover both rectangular and circular cross-sectional solid blocks. Normalization of simplified model equations in reference to the steady solution enables the solution to be expressed in a generalized form depending on the liquid-to-solid density ratio only. A selected result shows an excellent agreement with the previously reported numerical data, which justifies the present approach. The solution appears to be capable of describing all the fundamental characteristics of the transient process. In particular, dependence of the solid descending velocity oft the density ratio at the early stage of melting is successfully resolved. The effects of other parameters except the density ratio on the transient behaviors are efficiently represented via the steady solution implied in the normalized result. A simple approximate method for estimating the effect of convection on heat transfer across the liquid film is also proposed.

• Proceedings of the Korean Society for Agricultural Machinery Conference
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• 1996.06c
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• pp.780-791
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• 1996

A hybrid image processing system which automatically distinguished lean tissues in the image of a complex beef cut surface and generated the lean tissue contour has been developed. Because of the in homegeneous distribution and fuzzy pattern of fat and lean tissue on the beef cut, conventional image segmentation and contour generation algorithm suffer from a heavy computing requirement, algorithm complexity and poor robustness. The proposed system utilizes an artificial neural network enhance the robustness of processing. The system is composed of pre-network , network and post-network processing stages. At the pre-network stage, gray level images of beef cuts were segmented and resized to be adequate to the network input. Features such as fat and bone were enhanced and the enhanced input image was converted tot he grid pattern image, whose grid was formed as 4 X4 pixel size. at the network stage, the normalized gray value of each grid image was taken as the network input. Th pre-trained network generated the grid image output of the isolated lean tissue. A training scheme of the network and the separating performance were presented and analyzed. The developed hybrid system showed the feasibility of the human like robust object segmentation and contour generation for the complex , fuzzy and irregular image.

• Journal of Korean Society of Rural Planning
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• v.23 no.3
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• pp.37-51
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• 2017

There has been a growing concern on ontology especially in recent knowledge-based industry and defining a field-customized semantic word network is essential for building it. In this paper, a word network for ontology is established with 785 publications of Korean Society of Rural Planning(KSRP), from 1995 to 2017. Semantic relationships between words in the publications were quantitatively measured with the 'normalized pointwise mutual information' based on the information theory. Appearance and co-appearance frequencies of nouns and adjectives in phrases are analyzed based on the assumption that a 'noun phrase' represents a single 'concept'. The word network of KSRP was compared with that of $WordNet^{TM}$, a world-wide thesaurus network, for the verification. It is proved that the KSRP's word network, established in this paper, provides words' semantic relationships based on the common concepts of Korean rural planning research field. With the results, it is expecting that the established word network can present more opportunity for preparation of the fourth industrial revolution to the field of the Korean rural planning.

• Physical Therapy Korea
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• v.16 no.2
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• pp.59-66
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• 2009

This study investigated the irradiation pattern of muscles on the affected side in stroke patients after application of diagonal 2 extension (D2 ex) proprioceptive neuromuscular facilitation in the unaffected upper extremity. Seven stroke patients participated. Electromyographic activities were recorded in the iliopsoas, biceps brachii, and triceps brachii were recorded by surface electrodes at rest, D2 ex with knee extension, and D2 ex with knee 90 flexion, normalized by maximal voluntary isometric contraction (MVIC) values. The medial frequencies of biceps brachii in both sides were also measured to compare muscle type recruited. %MVIC of biceps brachii and triceps brachii were significantly higher in D2 ex than at rest (p<.05). There was no difference in median frequency of biceps brachii between the affected and unaffected side (p>.05). This suggests that proprioceptive neuromuscular facilitation using D2 ex may improve muscle activities of the paretic side and that the irritation pattern of the affected side may respond to maintain body equilibrium according to movement of the sound side.

• Korean Journal of Applied Biomechanics
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• v.16 no.2
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• pp.37-44
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• 2006

The purposes of this study were to analyze and compare EMG activities of the pectoralis major, biceps brachii, triceps brachii, and brachioradialis muscles during biceps curls using a VRT device and an elastic tubing. Fifteen male college students were recruited as subjects and they performed 10-RM and 20-RM biceps curls. For each load and device condition, the mean and peak normalized EMG levels during different phases of a biceps curl were computed. For each load and phase, paired t-test (p.05) was used to find the significant difference between two devices. ANOVA with repeated measures was also used to find the significant difference among phases in terms of EMG values for each muscle. For each load and device condition, the peak and mean EMG levels during different phases of a biceps curl were computed The significant differences between devices were found in biceps brachii for EA, MD, LD phases, and triceps brachii muscles for all phases, respectively. However, no differences were found among phases for any muscle. This indicated that elastic band could have a similar characteristics of VRT. High antagonistic muscle activity as a function of injury prevention which found particularly in VRT device may suggest that elastic tubing can be a safer training device than VRT. This also imply that elastic tubing could be very effective as a home exercise tool for rehabilitation patients and elderly people.