• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.10a
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• pp.576-580
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• 2005

New real-time confocal microscopy using spectral encoding technique and slit confocal aperture is proposed and designed. Spectral encoding technique, which encodes one-dimensional spatial information of a specimen in wavelength, and slit aperture make it possible to obtain two-dimensional lateral image of the specimen simultaneously at standard video rates without expensive scanning units such as polygon mirrors and galvano mirrors. The working principle and the configuration of the system are explained. The variation in axial responses for the simplified model of the system with normalized slit width is numerically analyzed based on the wave optics theory. Slit width that directly affects the depth discrimination of the system is determined by a compromise between axial resolution and signal intensity from the simulation result. On the assumption of the lateral sampling resolution of 50 nm, design variables and governing equations of the system are derived. The system is designed to have the mapping error less than the half pixel size, to be diffraction-limited and to have the maximum illumination efficiency. The designed system has the FOV of $12.8um{\times}9.6um$, the theoretical axial FWHM of 1.1 um and the lateral magnification of-367.8.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.6 no.1
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• pp.395-405
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• 2012

A joint template matching algorithm is proposed in this paper to reduce the high rate of miss-detection and false-alarm caused by the traditional template matching algorithm during the process of multi-object detection. The proposed algorithm can reduce the influence on each object by matching all objects together according to the correlation information among different objects. Moreover, the rate of miss-detection and false-alarm in the process of single-template matching is also reduced based on the algorithm. In this paper, firstly, joint template is created from the information of relative positions among different objects. Then, matching criterion according to normalized cross correlation is generated for multi-object matching. Finally, the proposed algorithm is applied to the detection of watermarks in bill. The experiments show that the proposed algorithm has lower miss-detection and false-alarm rate comparing to the traditional NCC algorithm during the process of multi-object detection.

• Structural Engineering and Mechanics
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• v.57 no.1
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• pp.179-200
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• 2016

In this paper the differential transformation method (DTM) is utilized for vibration and buckling analysis of nanotubes in thermal environment while considering the coupled surface and nonlocal effects. The Eringen's nonlocal elasticity theory takes into account the effect of small size while the Gurtin-Murdoch model is used to incorporate the surface effects (SE). The derived governing differential equations are solved by DTM which demonstrated to have high precision and computational efficiency in the vibration analysis of nanobeams. The detailed mathematical derivations are presented and numerical investigations are performed while the emphasis is placed on investigating the effect of thermal loading, small scale and surface effects, mode number, thickness ratio and boundary conditions on the normalized natural frequencies and critical buckling loads of the nanobeams in detail. The results show that the surface effects lead to an increase in natural frequency and critical buckling load of nanotubes. It is explicitly shown that the vibration and buckling of a nanotube is significantly influenced by these effects and the influence of thermal loadings and nonlocal effects are minimal.

• Advances in nano research
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• v.4 no.2
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• pp.85-111
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• 2016

In this paper, the classical and non-classical boundary conditions effect on free vibration characteristics of functionally graded (FG) size-dependent nanobeams are investigated by presenting a semi analytical differential transform method (DTM) for the first time. Three kinds of mathematical models, namely; power law (P-FGM), sigmoid (S-FGM) and Mori-Tanaka (MT-FGM) distribution are considered to describe the material properties in the thickness direction. The nonlocal Eringen theory takes into account the effect of small size, which enables the present model to become effective in the analysis and design of nanosensors and nanoactuators. Governing equations are derived through Hamilton's principle and they are solved applying semi analytical differential transform method. The good agreement between the results of this article and those available in literature validated the presented approach. The detailed mathematical derivations are presented and numerical investigations are performed while the emphasis is placed on investigating the effect of the several parameters such as small scale effects, spring constant factors, various material compositions and mode number on the normalized natural frequencies of the FG nanobeams in detail. It is explicitly shown that the vibration of FG nanobeams is significantly influenced by these effects. Numerical results are presented to serve as benchmarks for future analyses of FG nanobeams.

• Biomolecules & Therapeutics
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• v.23 no.3
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• pp.268-274
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• 2015

${\gamma}$-Aminobutyric acid (GABA), a major inhibitory neurotransmitter in the mammalian central nervous system, is involved in sleep physiology. Caffeine is widely used psychoactive substance known to induce wakefulness and insomnia to its consumers. This study was performed to examine whether GABA extracts from fermented rice germ ameliorates caffeine-induced sleep disturbance in mice, without affecting spontaneous locomotor activity and motor coordination. Indeed, caffeine (10 mg/kg, i.p.) delayed sleep onset and reduced sleep duration of mice. Conversely, rice germ ferment extracts-GABA treatment (10, 30, or 100 mg/kg, p.o.), especially at 100 mg/kg, normalized the sleep disturbance induced by caffeine. In locomotor tests, rice germ ferment extracts-GABA slightly but not significantly reduced the caffeine-induced increase in locomotor activity without affecting motor coordination. Additionally, rice germ ferment extracts-GABA per se did not affect the spontaneous locomotor activity and motor coordination of mice. In conclusion, rice germ ferment extracts-GABA supplementation can counter the sleep disturbance induced by caffeine, without affecting the general locomotor activities of mice.

• 한국연소학회:학술대회논문집
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• 2006.10a
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• pp.60-64
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• 2006

Propagation rates ($U_{edge}$) of various premixed, twin edge-flames were measured as a function of global strain rate ($\sigma$), mixture strength, and Lewis number (Le). Using a counterflow slot-jet burner with electrical heaters at each end, both advancing (positive $U_{edge}$) and retreating (negative $U_{edge}$) edge-flames can be studied as they propagate along the long dimension of the burner. Experimental results are presented for premixed methane/air twin flames in terms of the effects of $\sigma$ on $U_{edge}$. Both low-$\sigma$ and high-$\sigma$ extinction limits were discovered for all mixtures tested. As a result, the domain of edge-flame stability was obtained in terms of heat loss factor and normalized flame thickness, and comparison with the numerical result of other researchers was also made. For low ($CH_4/O_2/CO_2$) and high ($C_3H_8$/air) Lewis number cases, propagation rates clearly show a strong dependence on Le.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.12 no.1
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• pp.72-81
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• 1990

Because failure of microvascular flap grafting has sometimes been attributed to vascular obstruction in the anastomotic site, this study investigated the healing process after microvascular anastomoses. The healing process of anastomotic sites were observed by the use of the light and the scanning electron microscope after microvascular anastomoses of the right common carotid artery in rats. The experimental animals were sacrificed on the 4th day, 1st, 2nd, 4th and 6th week. Throughout the whole experimental period, arterial patency rate was 78% (11/14). At the early stage, it was possible to recognize histologically disappearance of endothelial cell and rupture of part of the media. Subintimal hyperplasia and the growth of media appeared around the suture line at the 2nd week. Endothelial cell regeneration occurred and the depth of vessel wall was normalized at the 4th week. By the scanning electron microscope, at the early stage, the anastomotic site was covered with many platelets, red blood cells, fibrins and macrophages. At the 4th week, the insertion site of the thread was completely covered with normal endothelial cells which were parallel to longitudinal axis of vessels and complete reendothelialization over the anastomotic site seemed to take about 6th week.

• Korean Journal of Optics and Photonics
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• v.19 no.6
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• pp.408-415
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• 2008

The characteristics of a ferroelectric-domain inverted grating fabricated by applying a high-voltage pulse at room temperature in Ti-diffused channel waveguides in z-cut $LiNbO_3$ (Ti:PPLN) were examined for channel waveguide quasi phase-matched secondharmonic generation devices. The fabrication conditions of uniform periodic domain-inversion were examined. Ti:PPLN with period ${\Lambda}=16.6{\mu}m$ for SHG were fabricated and the performances were measured. A normalized SHG efficiency as high as 473 (%/W) was obtained with 49 mm interaction length.

• Physical Therapy Korea
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• v.16 no.4
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• pp.16-22
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• 2009

The purpose of this study was to investigate the trunk and lower extremity muscle activity induced by three different intensity conditions (intensity 1, 3, 5) of whole body vibration (WBV) during bridging exercise. Surface electromyography (EMG) was used to measure trunk and lower extremity muscles activity. Eleven healthy young subjects (6 males, 5 females) were recruited from university students. The collected EMG data were normalized using reference contraction (no vibration during bridging) and expressed as a percentage of reference voluntary contraction. To analyze the differences in EMG data, the repeated one-way analysis of variance was used. A Bonferroni's correction was used for multiple comparisons. The study showed that EMG activity of the rectus abdominis, external oblique, internal oblique, erector spinae and rectus femoris muscles was not significantly different among three intensity conditions of WBV during bridging exercise (p>.05). However, there were significantly increased EMG activity of the medial hamstring muscle (p=.001) and medial gastrocnemius muscle (p=.027) in the intensity 3 condition compared with the intensity 1 condition. This result can be interpreted that vibration was absorbed through the distal muscles, plantar flexor and knee flexor.

• Journal of Korea Multimedia Society
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• v.19 no.2
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• pp.189-199
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• 2016

Many implantable hearing aids are being developed as alternatives to conventional hearing aids which has inconveniences for use and social stigma that make hearing-impaired people avoid to wear it. Particularly, the fully-implantable middle ear hearing devices (F-IMEHD) are being actively studied for mixed or sensorineural hearing impaired people. In development of F-IMEHD, the most difficult problem is improving the performance of implantable microphone. Recently, Cho et al. have studied the tympanic membrane installed microphone which has better sensitivity and is easier to operate on patient than the microphone implanted under the skin. But, it may cause howling problem due to the feedback signal via oval window and ossicle chain from the transducer on round window in the middle ear cavity, therefore, a feedback canceller is necessary. In this paper, we designed NLMS (normalized least mean square) adaptive feedback canceller for F-IMEHD with tympanic membrane installed microphone and a transducer implemented at round window, and computer simulation was performed to verify its operation. The designed adaptive feedback canceller has a delay filter, a 64 point FIR fixed filter and a 8-tap adaptive FIR filter. Computer simulation of the feedback path is modeled by using the data obtained through human cadaver experiment.