• 터널과지하공간
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• 제21권3호
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• pp.192-204
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• 2011

본 연구에서는 시공단계를 정확하게 고려하여 3차원 해석을 수행하고, 이와 동일한 결과를 나타내는 2차원 해석 결과를 얻고자 천단변위를 기준으로 하여 하중분배율을 결정하였다. 2차원 해석 결과와 3차원 해석 결과에서 천단변위의 총량에는 차이가 있어, 이를 극복하고자 각 단계에서의 천단변위 값을 총 변위량으로 나눈 '천단변위비'를 비교 대상으로 정하였다. 또한 숏벤치 공법이나 미니벤치 공법의 경우에서처럼 상하 반단면 분할굴착에서 벤치의 길이가 짧은 경우에는 하부 반단면의 굴착이 완료된 후에도 굴진면의 지지효과가 사라지지 않는 상황이 발생한다. 이러한 상황을 해석에 반영하고자 4번째 하중분배계수를 도입하여 굴진면 전진 효과를 구현하도록 하였다. 그 결과 전단면 굴착, 상하 반단면 분할굴착, 벤치 길이의 변화 및 초기 응력 상태 등을 고려한 다양한 경우에 대하여 합리적으로 하중분배율을 결정하는 방법을 제시하였다.

• 한국수산과학회지
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• 제52권4호
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• pp.382-388
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• 2019

Streptococcosis caused by Streptococcus parauberis is a very important disease in farmed olive flounder Paralichthys olivaceus. For most fish pathogens, including S. parauberis, there are no analytical criteria to distinguish antibioticsusceptible strains from antibiotic-resistant strains. In this study, epidemiological cut-off ($CO_{WT}$) values were generated to classify 75 strains of S. parauberis isolated from 1999 to 2018 as wild type (WT) and non-wild type (NWT) using disc diffusion data and normalized resistance interpretation (NRI) analysis. The susceptibility of the isolates to 16 antibiotics was evaluated using CLSI guideline M42-A. The wild-type cut-off values for amoxicillin, erythromycin, oxytetracycline, and florfenicol for S. parauberis were ${\geq}35$, 31, 28, and 27 mm, respectively. The NWT ratios of S. parauberis strains to treatment with GEN, FFC, ENR, SXT, EFT, VAN, and CHL were 17% or less, indicating that these antibiotics may be used to treat streptococcosis caused by S. parauberis. For recent S. parauberis isolates, the NWT ratios for AMX, ERY, OTC and FFC are much higher than for strains isolated from 1999-2007. The $CO_{WT}$ data from this study will assist aquatic animal disease professionals in prescribing appropriate antibiotics for the treatment of streptococcosis caused by S. parauberis, which will help reduce the misuse and abuse of antibiotics in the aquaculture sector.

• 음성과학
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• 제11권3호
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• pp.157-164
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• 2004

Human has average pitch-level when speak naturally. That is 'Habitual pitch level'. However, if noise added at speech, the pitch-wave is changed irregularly. We can estimate noise level of speech by using this point. This paper calculates energy level of the input speech, pitch period from of above limited energy level by NAMDF (Normalized Average Magnitude Difference Function) method, after cut each frame by pitch period unit, and propose a method that estimate noise level through closed pitch of input speech.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1992년도 하계학술대회 논문집 B
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• pp.757-758
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• 1992

At-cut quarts crystal has been applied as chemical vapour sensors. The responses of quartz crystal at 9 MHz coated with various lipids were determined for organic gases which showed different affinities for each lipid. The identification of odorants depending on the species of lipid used for coating is discussed in terms of the normalized resonant frequency shift pattern.

• E2M - 전기 전자와 첨단 소재
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• 제9권3호
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• pp.298-303
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• 1996

A double diffusion technique is developed to enhance the effective mode index of optical waveguides in $LiTaO_3$. It consists of Zn diffusion from the vapor phase at relatively low temperatures (750->$800^{\circ}C$), into waveguides initially produced by Ti indiffusion at higher temperature (1150->$1200^{\circ}C$). Both X- and Z-cut substrates are investigated. A model that combines profiles of both diffusion is formulated to calculate the expected effective index values for planar waveguides. Good agreement is found between experimental results and model predictions which assume that the initial Ti profile is not affected by the lower temperature Zn diffusion. Effective index enhancements as high as 0.005 and 0.003 are obtained by this method for the fundamental extraordinary and ordinary modes, respectively.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2003년도 추계학술대회 논문집(II)
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• pp.466-471
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• 2003

The characteristics of a rock joint which influence the stability of rock mass structures, such as the cut slopes and the tunnels, are largely controlled by the conditions of the rock joint as well as its boundary conditions. Boundary conditions can be represented by assuming that the deformability(or stiffness) of the rock mass surrounding the joints is modelled by a spring with stiffness. A new direct shear apparatus is developed in this study, which adapts a servo control system using PID algorithm. This apparatus can be used to investigate the various aspects of shear characteristics of the rock joints at conditions of constant normal stress and constant normal stiffness and so on. It is possible that the behavior under the constant normal stiffness condition can be predicted by the normalized graphic method with results obtained from the tests in the constant normal stress condition.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1993년도 정기총회 및 추계학술대회 논문집 학회본부
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• pp.246-248
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• 1993

We investigated the responses of six types of lipid-coated AT-cut quartz crystal resonators to chemical vapour sensors. The responses of quartz crystal at 9 MHz coated with phosphatidylglycerol (PG), phosphatidylinositol(PI), phosphatidylethanolamine(PE), phosphatidylserine(PS), and lipid A(LA) were obtained for amyl acetate, acetoin, menthane and other organic gases which showed different affinities for each lipid. The identification of odorants depending on the species of lipid used for coating is discussed in terms of the normalized resonant frequency shift pattern.

• 한국정보과학회논문지:소프트웨어및응용
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• 제36권11호
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• pp.936-946
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• 2009

그래프 컷(graph cuts) 방법은 주어진 사전정보와 각 픽셀간의 유사도를 나타내는 데이터 항(data term)과 이웃하는 픽셀간의 유사도를 나타내는 스무드 항(smoothness term)으로 구성된 에너지 함수를 전역적으로 최소화하는 방법으로, 최근 영상 분할에 많이 이용되고 있다. 기존 그래프 컷 기반의 영상 분할 방법에서 데이터 항을 설정하기 위해 GMM(Gaussian mixture model)을 주로 이용하였으며, 평균과 공분산을 각 클래스를 위한 사전정보로 이용하였다. 이 때문에 클래스의 모양이 초구(hyper-sphere) 또는 초타원(hyper-ellipsoid)일 때만 좋은 성능을 보이는 단점이 있다. 다양한 클래스의 모양에서 좋은 성능을 보이기 위해, 본 논문에서는 mean shift 분석 방법을 이용한 그래프 컷 기반의 자동 영상분할 방법을 제안한다. 데이터 항을 설정하기 위해 $L^*u^*{\upsilon}^*$ 색상공간에서 임의로 선택된 초기 mean으로부터 밀도가 높은 지역인 모드(mode)로 이동하는 mean의 집합들을 사전정보로 이용한다. Mean shift 분석 방법은 군집화에서 좋은 성능을 보이지만, 오랜 수행시간이 소요되는 단점이 있다. 이를 해결하기 위해 특징공간을 3차원 격자로 변형하였으며, mean의 이동은 격자에서 모든 픽셀이 아닌 3차원 윈도우내의 1차원 모멘트(moment)를 이용한다. 실험에서 GMM을 이용한 그래프 컷 기반의 영상분할 방법과 최근 많이 이용되고 있는 mean shift와 normalized cut기반의 영상분할 방법을 제안된 방법과 비교하였으며, Berkeley dataset을 기반으로 앞의 세 가지 방법보다 좋은 성능을 보였다.

• Korean Journal of Acupuncture
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• 제23권3호
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• pp.133-160
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• 2006

Objectives : Scolopendrae Corpus has a broad array of clinical applications in Korean medicine, including treatment of inflammatory conditions such as arthritis. To explore the global gene expression profiles in human Raw cell lines treated with Scolopendrae Corpus herbal-acupuncture solution (SCHAS), cDNA microarray analysis was performed. Methods : The Raw 264.7 cells were treated with lipopolysaccharide (LPS), SCHAS, or both. The primary data was normalized by the total spots of intensity between two groups, and then normalized by the intensity ratio of reference genes such as housekeeping genes in both groups. The expression ratio was converted to log2 ratio. Normalized spot intensities were calculated into gene expression ratios between the control and treatment groups. Greater than 2 fold changes between two groups were considered to be of significance. Results : Of the 8 K genes profiled in this study, with a cut-off level of two-fold change in the expression, 20 genes (BCL2-related protein A1, MARCKS-like 1, etc.) were upregulated and 5 genes (activated RNA polymerase II transcription cofactor 4, calcium binding atopy-related autoantigen 1, etc.) downregulated following LPS treatment. 139 genes (kell blood group precursor (McLeod phenotype), ribosomal protein S7, etc.) were upregulated and 42 genes (anterior gradient 2 homolog (xenopus laevis), phosphodiesterase 8B, etc.) were downregulated following SCHAS treatment. And 10 genes (yeast saccharomyces cerevisiae intergeneic sequence 4-1, mitogen-activated protein kinase 1, etc.) were upregulated and 8 genes (spermatid perinuclear RNA binding protein, nuclear receptor binding protein 2, etc.) were downregulated following co-stimulation of SCHAS and LPS. Discussions : It is thought that microarrays will play an ever-growing role in the advance of our understanding of the pharmacological actions of SCHAS in the treatment of arthritis. But further studies are required to concretely prove the effectiveness of SCHAS.

• 한국광학회지
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• 제19권6호
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• pp.408-415
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• 2008

고전압 펄스를 인가시켜서 주기적으로 도메인을 반전시키는 공정을 검토하였으며, 이를 적용해서 제작된 Ti 확산 리튬나오베이트 채널광도파로(Ti:PPLN) 기반의 의사 위상정합 2차 조화파 발생을 체계적으로 측정하였다. 2차 조화파 발생을 위해서 $16.6{\mu}m$ 분극 주기와 49 mm 길이의 Ti:PPLN 채널광도파로를 제작하였으며, 473(%/W) 변환효율이 측정되었다.