• 음성과학
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• 제12권1호
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• pp.27-35
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• 2005

Differential instrumentation for the diagnoses of individuals with Cleft palate has been used to objectively measure speech problems. The Cepstrum Method was used to study the vocal tract transfer function. The vocal tract transfer function and the source spectrum should be considered in the evaluation of nasal resonance. The aim of this study was to collect quantitative data on the acoustic Instrumentation used for evaluating hypernasality. Normal subjects (9 male, 21 female; 37 male children, 20 female children) and individuals with VPI (13 male, 8 female; 16 male children, 9 female) participated in this study. The vowel /i/ was selected to gauge the severances of hypernasality Spectral and Cepstral studies using CSL was used to identify the acoustic characteristics. Cepstrum analysis shows significant differences in quefrency and amplitude. The quefrency of normal groups was shorter than that of the VPI groups, while the amplitude of normal groups was lower than that of the VPI groups. This may have significance in the evaluation 'of nasal resonance.

• 대한핵의학회지
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• 제37권1호
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• pp.63-72
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• 2003

Functional MRI (fMRI) provides an indirect mapping of cerebral activity, based on the detection of the local blood flow and oxygenation changes following neuronal activity (Blood Oxygenation Level Dependent). fMRI allows us to study noninvasively the normal and pathological aspects of functional cortical organization. Each fMRI study compares two different states of activity. Echo-Planar Imaging is the technique that makes it possible to study the whole brain at a rapid pace. Activation maps are calculated from a statistical analysis of the local signal changes. fMRI is now becoming an essential tool in the neurofunctional evaluation of normal volunteers and many neurological patients as well as the reference method to image normal or pathologic functional brain organization.

• Journal of Oral Medicine and Pain
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• 제25권1호
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• pp.73-85
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• 2000

The purposes of the study were (1) to see if there are various types of disc configuration in normal temporomandibular joint and, if so, (2) to examine whether a specific type of disc configuration is susceptible to disc displacement, and (3) to see if a specific type of disc configuration and position is related to early relief of clinical symptoms from the anterior disc displacement without reduction to conservative treatment. From the magnetic resonance (MR) images taken for the patients with symptoms of temporomandibular disorders, 235 images as normal joint group, 255 images as anterior disc displacement with reduction group, and 249 images as anterior disc displacement without reduction group were selected, After the TMJ image was scanned and processed with Photoshop program, the disc configuration was determined, The incidence of various types of disc configuration was analyzed according to age, sex, diagnostic group, and the promptness of symptom relief. The disc position was also examined in relation to the promptness of symptom relief. The results were as follows : 1. In the normal joint group, biconcave type appeared most frequently and reversed, biplanar type in order, Posterior band enlarged and folded type didn't appear at all. On the other hand, in the anterior disc displacement without reduction group, folded type appeared most frequently and also posterior band enlarged type were found often. 2. There were statistically significant differences between sex and configuration of disc in the normal joint group and no statistically significant differences in the anterior disc displacement with reduction group and anterior disc displacement without reduction group, 3. There were no statistically significant differences between age and configuration of disc in the normal, anterior disc displacement with reduction group and anterior disc displacement without reduction group. 4. In anterior disc displacement without reduction group, rapid response was observed in biconcave and reversed type and delayed response was observed in folded type.

• Journal of Yeungnam Medical Science
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• 제39권4호
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• pp.300-308
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• 2022

Background: This study investigated the prognostic impact of spine magnetic resonance imaging (MRI) in patients newly diagnosed with multiple myeloma (MM). Methods: We retrospectively evaluated 214 patients who were newly diagnosed with MM between March 2015 and December 2019. The patients were classified into five different infiltration patterns based on spine MRI as follows: (1) normal appearance, (2) focal, (3) diffuse, (4) combined focal and diffuse infiltration, and (5) "salt-and-pepper." Results: Forty patients (18.7%) showed a normal appearance, whereas focal, diffuse, combined focal and diffuse infiltration, and "salt-and-pepper" patterns were identified in 68 (31.8%), 40 (18.7%), 52 (24.3%), and 14 patients (6.5%), respectively. The patients with normal and "salt-and-pepper" patterns were younger than patients with other patterns (median age, 61.6 vs. 66.8 years; p=0.001). Moreover, 63% and 59.3% of patients with normal and "salt-and-pepper" patterns were scored International Staging System (ISS) stage I and revised ISS (R-ISS) stage I, respectively, whereas only 12.5% of patients with other patterns were scored ISS stage I and R-ISS stage I. Patients with normal and "salt-and-pepper" patterns had a better prognosis than those with other patterns, whereas relapse and death rates were significantly higher in patients with focal, diffuse, and combined MRI patterns. Conclusion: Characteristic MRI findings have a significant prognostic value for long-term survival in patients newly diagnosed with MM. In particular, focal, diffuse, and combined focal and diffuse infiltration patterns are unfavorable prognostic factors.

• 한국초전도ㆍ저온공학회논문지
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• 제17권1호
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• pp.36-39
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• 2015

Many studies are being conducted to implement wireless charging, for example, for cellular phones or electronic tooth brushes, via wireless power transmission technique. However, the magnetic induction method had a very short transmission distance. To solve this problem, the team of Professor Marin Soljacic proposed a magnetic resonance system that used two resonance coils with the same resonance frequency. It had an approximately 40% efficiency at a 2m distance. The system improved the low efficiency and short distance problems of the existing systems. So it could also widen the application range of wireless power transmission. Many studies on the subject are underway. In this paper, the superconductor coil was used to improve the efficiency of magnetic resonance wireless power transmission. The resonance wireless power transmission system had a source coil, a load coil, and resonance coils (a transmitter and a receiver). The efficiency and distance depended on the characteristics of the transmitter and receiver coils that had the same resonance frequency. Therefore, two resonance coils were fabricated by superconductors. The current density of the superconductor was higher than that of the normal conductor coil. Accordingly, it had a high quality-factor and improved efficiency.

• Journal of Veterinary Science
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• 제22권1호
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• pp.2.1-2.10
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• 2021

Background: Diseases related to cerebrospinal fluid flow, such as hydrocephalus, syringomyelia, and Chiari malformation, are often found in small dogs. Although studies in human medicine have revealed a correlation with cerebrospinal fluid flow in these diseases by magnetic resonance imaging, there is little information and no standard data for normal dogs. Objectives: The purpose of this study was to obtain cerebrospinal fluid flow velocity data from the cerebral aqueduct and subarachnoid space at the foramen magnum in healthy beagle dogs. Methods: Six healthy beagle dogs were used in this experimental study. The dogs underwent phase-contrast and time-spatial labeling inversion pulse magnetic resonance imaging. Flow rate variations in the cerebrospinal fluid were observed using sagittal time-spatial labeling inversion pulse images. The pattern and velocity of cerebrospinal fluid flow were assessed using phase-contrast magnetic resonance imaging within the subarachnoid space at the foramen magnum level and the cerebral aqueduct. Results: In the ventral aspect of the subarachnoid space and cerebral aqueduct, the cerebrospinal fluid was characterized by a bidirectional flow throughout the cardiac cycle. The mean ± SD peak velocities through the ventral and dorsal aspects of the subarachnoid space and the cerebral aqueduct were 1.39 ± 0.13, 0.32 ± 0.12, and 0.76 ± 0.43 cm/s, respectively. Conclusions: Noninvasive visualization of cerebrospinal fluid flow movement with magnetic resonance imaging was feasible, and a reference dataset of cerebrospinal fluid flow peak velocities was obtained through the cervical subarachnoid space and cerebral aqueduct in healthy dogs.

• Investigative Magnetic Resonance Imaging
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• 제25권4호
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• pp.281-292
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• 2021

Cranial-nerve disorders can be caused by a wide spectrum of diseases, including congenital, inflammatory, and tumorous diseases, and are often encountered in practice. However, the imaging of cranial-nerve disorders is challenging, and understanding the anatomical differences of each region is essential for conducting the best protocols and for detecting subtle changes in cranial nerves during magnetic resonance imaging (MRI) examinations. In this review we discuss which MRI techniques are best for observing normal and pathologic appearance, according to the different regions of the cranial nerves.

• 한국자기공명학회논문지
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• 제10권2호
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• pp.126-140
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• 2006

Purpose: Contrary to the human study, it has rarely investigated metabolic alterations in the dorsolateral prefrontal cortex (DLPFC) of depressed rats versus age and sex-matched controls using proton magnetic resonance spectroscopy (MRS). Thus, the purpose of this research was to verify the feasibility of metabolic differences between the normal rat and the depression model rat. Materials and Methods: A homogeneous group of 20 SD male rats was used for MRI and in vivo 1H MRS. To induce a depressed status in SD rats, we performed the forced swimming test (FST). Using image-guide, water suppressed in vivo 1H MRS with 4.7 T MRI/MRS system, NAA/Cr and Cho/Cr ratios were mainly measured between depressed rats and normal subjects. Results: In depressed rats, increased Cho/Cr ratio was measured versus control subjects. However, no significant group effect for NAA/Cr was observed between case-control pairs. Discussion and Conclusions: The present 1H MRS study shows significant brain metabolic alterations of dorsolateral prefrontal cortex with experimental depressed status of SD rat induced by FST compared to normal subjects. This result provides new evidence that in vivo 1 H MRS may be a useful modality for detecting localized functional neurochemical markers alterations in left DLPFC in SD rats.

• Steel and Composite Structures
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• 제51권4호
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• pp.391-406
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• 2024

The present research investigates the combination resonance behaviors of porous FG shallow shells reinforced with oblique stiffeners and subjected to a two-term excitation. The oblique stiffeners considered in this research reinforce the shell internally and externally. To model the stiffeners, Lekhnitskii's smeared stiffeners technique is utilized. According to the first-order shear deformation theory (FSDT) and stress functions, a nonlinear model of the oblique stiffened shallow shell is established. With regard to the FSDT and von-Kármán nonlinear geometric assumptions, the stress-strain relationships for the present shell system are developed. Also, in order to discretize the nonlinear governing equations, the Galerkin method is implemented. To obtain the required relations for investigating the combination resonance theoretically, the method of multiple scales is applied. For verifying the results of the present research, generated results are compared with previous research. Additionally, a comparison with the P-T method is conducted to increase the validity of the generated results, as this method has illustrated advantages over other numerical methods in terms of accuracy and reliability. In this method, the piecewise constant argument is used jointly with the Taylor series expansion, which is why it is named the P-T method. The effects of stiffeners with different angles, and the effects of material parameters on the combination resonance behaviors of the present system are addressed. With the findings of this research, researchers and engineers in this field may use them as benchmarks for their design and research of porous FG shallow shells.

• Investigative Magnetic Resonance Imaging
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• 제21권4호
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• pp.199-209
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• 2017

Purpose: Caffeine is the most widely consumed psychostimulant. It is often adopted as a tool to modulate brain activations in fMRI studies. However, its pharmaceutical effect on task-induced deactivation has not been fully examined in fMRI. Therefore, the purpose of this study was to examine the effect of caffeine on both activation and deactivation under sustained attention. Materials and Methods: Task fMRI was acquired from 26 caffeine naive healthy volunteers before and after taking caffeine pill (200 mg). Results: Statistical analysis showed an increase in cognition-load dependent task activation but a decrease in load dependent de-activation after caffeine ingestion. Increase of attention and memory task activation and its load-dependence suggest a beneficial effect of caffeine on the brain even though it has no overt behavior improvement. The reduction of deactivation by caffeine and its load-dependence indicate reduced facilitation from task-negative networks. Conclusion: Caffeine affects brain activity in a load-dependent manner accompanied by a disassociation between task-positive network and task-negative network.