• Title/Summary/Keyword: normal ranges

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Stem cell therapy for dogs with immune-mediated hemolytic anemia

  • Yeonmi Lee;Eunju Kang;Junguk Ju
    • Journal of Animal Reproduction and Biotechnology
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    • v.39 no.1
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    • pp.58-61
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    • 2024
  • Three different dogs who had immune-mediated hemolytic anemia (IMHA) were treated for more than two weeks with blood transfusion in an animal clinic. Despite this treatment and hospitalization, there was no clinical improvement in clinical signs as well as complete blood cell count (CBC) including hematocrit (HCT) and C-reactive protein (CRP). All cases were then injected two or three times with allogeneic stem cells through an intravenous route for treatment. Upon administrating stem cells to the IMHA dogs, clinical conditions and the indexes of HCT and CRP were clinically improved within or close to normal ranges.

Effects of High Carbohydrate Diets on Serum Glucose and lipid Values of Normal and Alloxan-Diabetic Rats (고당질식이(高糖質食餌)가 정상(正常)쥐와 Alloxan 당뇨(糖尿)쥐의 혈당량(血糖量)과 혈청지질성분(血淸脂質成分)에 미치는 영향(影響))

  • Lee, Yong-Ock;Noh, Jang-Sook;Shin, Sul-Yong
    • Journal of the Korean Applied Science and Technology
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    • v.2 no.1
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    • pp.57-66
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    • 1985
  • The possible effects of 10% carbohydrate containting diets on the serum glucose and lipids values were studied with normal and alloxan - diabetic male rats for a period of 28 days. The diets were supplemented with either glucose, cornstarch or sucrose, fructose or the basal diet containing no added carbohy drates. After this period, 3 to 4 rats among the each group were killed and samples of serum, liver, spleen and kidney were collected. The others were rendered diabetic by the intraperitoneal injection of alloxan ($190mg/\frac{wt}{kg}$). Then original feeding scedule was continued for 3 days in all five diabetic groups, before the collection of tissue samples and serum. Feeding the nondiabetic rats with glucose and fructose delayed the bodyweight development relatively compared with nonsugar group. The weight deductions after alloxan injection were similar in all feeding groups. All diabetic animals exhibited increased blood glucose triglceride levels but almost unchanged total cholesterol values. Blood glucose values for nondiabetic rats were normal ranges, and then glucose feeding group was the highest. Total - cholesterol values were the highest in nondiabetic rats fed glucose, fructose and in diabetics fed sucrose, glucose. Triglyceride values were the highest in nondiabetic rats fed sucrose, and no difference in diabetic rats. Some cornstarch group exhibited fatty-livers in diabetic and nondiabetic, and more studies need.

Evaluation of Resistive Index Using Color Doppler Imaging in Canine Ophthalmic Vasculature (개의 안혈관에 대한 컬러도플러초음파를 사용한 저항지수의 평가)

  • Lee, Hee-Chun;Yoon, Jung-Hee
    • Journal of Veterinary Clinics
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    • v.20 no.2
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    • pp.145-149
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    • 2003
  • Color Doppler imaging(CDI) was carried out to determine CDI-derived resistive index(RI) values of normal canine ophthalmic vasculature and its reproducibility. CDI was performed on 58 dogs. and normal ranges of RI value were calculated for the medial long posterior ciliary artery(mLPCA), ciliary artery(CA), and ophthalmic artery(OA). Ophthalmic vascular RI values of normal dogs were 0.67$\pm$0.07, 0.70$\pm$0.06, and 0.80$\pm$0.04 in mLPCA, CA, and OA, respectively. Means of RT value of all vessel had no statistically significant difference by sex, fellow orbits, and skull type. The results suggest that color Doppler imaging is a noninvasive test which has the advantage of providing objective measurements of blood flow velocity parameter in the canine eye and orbit.

Clinical Applications of 3T MR Spectroscopy

  • Choe, Bo-Young;Baik, Hyun-Man;Chu, Myung-Ja;Jeun, Sin-Soo;Kang, Sei-Kwon;Chung, Sung-Taek;Park, Chi-Bong;Oh, Chang-Hyun;Lee, Hyoung-Koo
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.345-351
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    • 2002
  • The purpose of this study was to assess clinical proton MR spectroscopy (MRS) as a noninvasive method for evaluating brain tumor malignancy at 3T high field system. Using 3T MRI/MRS system, localized water-suppressed single-voxe1 technique in patients with brain tumors was employed to evaluate spectra with peaks of N-acetyl aspartate (NAA), choline-containing compounds (Cho), creatine/phosphocreatine (Cr) and lactate. On the basis of Cr, these peak areas were quantificated as a relative ratio. The variation of metabolites measurements of the designated region in 10 normal volunteers was less than 10%. Normal ranges of NAA/Cr and Cho/Cr ratios were 1.67${\pm}$018 and 1.16${\pm}$0.15, respectively. NAA/Cr ratio of all tumor tissues was significantly lower than that of the normal tissues (p=0.005), but Cho/Cr ratio of all tumor tissue was significantly higher (p=0.001). Cho/Cr ratio of high-grade gliomas was significantly higher than that of low-grade gliomas (P=0.001). Except 4 menigiomas, lactate signal was observed in all tumor cases. The present study demonstrated that the neuronal degradation or loss was observed in all tumor tissues. Higher grade of brain tumors was correlated with higher Cho/Cr ratio, indicating a significant dependence of Cho levels on malignancy of gliomas. Our results suggest that clinical proton MR spectroscopy could be useful to predict tumor malignancy.

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Study on the Morphological Parameters and Evolution of Caragana microphylla Lam. Nebkhas in Inner Mongolia, China

  • Na, Yan;Eerdun, Hasi;Park, Ki-Hyung;Xia, Xian-Dong;Chun, Kun-Woo
    • Journal of Korean Society of Forest Science
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    • v.98 no.2
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    • pp.156-162
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    • 2009
  • Nebkhas are widely distributed in farming-pastoral zones, typical grassland and desert margins. In the southeast of the Inner Mongolia Plateau, it is mainly distributed at the leeward of cultivated land and alluvial fan, severe deterioration rangeland and around residential points. Through the field measurement and statistical analysis of Caragana microphylla Lam. Nebkhas morphological parameters (length, width and height of Nebkhas are included), the results show that there were close correlations between the Nebkhas morphological parameters. The ranges of height and width of Nebkhas changed dramatically and have reached up to 11.44 m and 7.97 m respectively, however, the change range of height was relatively smaller and just 1.09 m. The morphological parameters change of the same type Nebkhas in the same region was large ranging from 0.56 m in height, 3.56 m in width to 6.96 m in length, while the morphological characteristics of the same type Nebkhas in different regions were much similar. A correlation between length and width was significantly positive, but the correlations between height and length, and between height and width were much more complicated. It can be concluded that the Nebkhas in Zhengxiangbai Banner and Taipusi Banner were at the initially growing stage, while the Nebkhas in Huade County belonged to a transitional stage from the growing phase to the stabilizing phase. The changing regularity of distance between Nebkhas in along-wind direction was not consistent.

MINERAL STATUS OF GRAZING PHILIPPINE GOATS II. THE NUTRITION OF SELENIUM, COPPER AND ZINC OF GOATS IN LUZON ISLAND

  • Fujihara, T.;Matsui, T.;Hayashi, S.;Robles, A.Y.;Serra, A.B.;Cruz, L.C.;Shimizu, H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.5 no.2
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    • pp.389-395
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    • 1992
  • Nutritional status of trace minerals (Se, Cu and Zn) in goats grazed on the native pasture was investigated during 2 years in Luzon Island, Republic of the Philippines. Three regions (South, Central and North) were objected to collect the samples of blood of goats and forages on the pasture. Se content of major species forages in the pasture was $24.7{\mu}g/kg$ DM, and was clearly lower than the value ($200{\mu}g/kg$ DM) required commonly for ruminant feed. The Cu and Zn contents of all forage samples ranged from 7.6 to 24.3 and 11.4 to 50.6 mg/kg DM, respectively, and these values almost exceeded the dietary level required for sheep. The blood Se levels in about 55% of goats grazed alone were under the normal range ($20{\mu}g/l$), but it in goats fed some concentrates as a supplement were almost within a normal ranges ($20-200{\mu}g/l$), though the Cu content of forages almost exceeded the dietary level required commonly. The 4-13% of plasma samples of goats without supplement showed the Zn level below the lower limit (0.6 mg/l) of normal range. The Zn deficiency was mostly improved by the addition of a small amount of concentrates. From these results, it will be necessary to study about unstable Cu status of grazed goats in Luzon Island regarding an interaction of Cu and other elements known to relate to the malabsorption of dietary Cu.

Utilization of Averaging Process of Blink Reflex to Improve Diagnosis of Facial Nerve Palsy

  • Yoo, Jong-Kyun;Cho, Jeong-Hee;Kim, Dea-Sik
    • Biomedical Science Letters
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    • v.18 no.4
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    • pp.391-398
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    • 2012
  • The conventional blink reflex has limited clinical application since it displays a wide range of change in the responses. Thus, we studied the blink reflex using the averaging process which is engaged in evoked potential studies in order to measure various responses such as latency, amplitude, and duration, which have been difficult to measure due to their wide ranges of changes. Among the Bell's palsy patient group, 13 patients who had the symptoms of incomplete palsy were examined to assess the results of the blink reflex through the averaging process. The subjects were 54 people in a normal group (108 eyes) and 18 patients (36 eyes) with Bell's palsy. For the study method, the conventional blink reflex and the blink reflex using the averaging process were measured for the people in the normal group, while in the Bell's palsy group, only the blink reflex using the averaging process was analyzed. In the case of the normal group, the blink reflex using the averaging process could measure all of the latency, amplitude, and duration. It was also observed that the latency, amplitude, and duration of R1, ipsilateral R2, and contralateral R2 significantly differed on the affected side of the Bell's palsy patients, compared to the unaffected side. The blink reflex using the averaging process should be more effective than the conventional method since the former can evaluate the latency, amplitude, and duration for Bell's palsy, while the latter can only assess latency.

Relationship between shear behavior characteristics and mechanical parameters of fractures (절리면에서의 전단거동 특성과 역학적 파라미터들 간의 상관성)

  • 이종욱;이찬구;황신일;장천중;최원학
    • The Journal of Engineering Geology
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    • v.3 no.1
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    • pp.1-20
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    • 1993
  • In this study, laboratory direct shear tests on 37 core specimens of gneiss were performed to examine the characteristics of shear behavior on fractures by using a portable direct shear box. The multi-stage shear testing method was used and normal stress applied to specimens ranges from 5.60 to $25.67kg/\textrm{cm}^2$. On the basis of test results, the empirical equations for the shear strength on fractures were suggested. The methanical parameters that can influence the shear behavior were derived and compared between each parameter. The values of shear stiffness have a trend showing rapid increase with the increase of normal stress and joint roughness coeffident, and the average value of secant shear stiffness for all specimens is about $110.68kg/\textrm{cm}^3$ under the range of normal stress applied in this test In addition, the relationship between the length of specimen and shear stiffness is inversely correlated due to the size effect. Therefore, even the specimens with the same joint roughness coeffident show the trend of decreasing shear stiffness in case of the specimens being the longer length.

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Determination of Femoral and Tibial Joint Reference Angles in Small-breed Dogs

  • Kim, Jooho;Heo, Suyoung;Na, Jiyoung;Kim, Namsoo;Kim, Minsu;Jeong, Seongmok;Lee, HaeBeom
    • Journal of Veterinary Clinics
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    • v.33 no.6
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    • pp.340-345
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    • 2016
  • The present study determined the normal reference ranges for the femoral and tibial joint orientation angles of small-breed dogs. For this purpose, 60 each of cadaveric canine femurs and tibias from normal small-breed dogs (Maltese, Poodle, Shih Tzu, Yorkshire Terrier) were examined with radiographs and photographs. Axial and frontal radiographs and photographs of each bone were obtained, from which anteversion and inclination angles, anatomic lateral proximal and distal femoral angles (aLPFA and aLDFA), mechanical lateral proximal and distal femoral angles (mLPFA and mLDFA), and mechanical medial proximal and distal tibial angles (mMPTA and mMDTA) were measured. The 95% CI for radiographic values of all femurs and tibiae were anteversion angle, $23.4-27.4^{\circ}$; inclination angle, $128.4-130.4^{\circ}$; aLPFA, $117.8-122.1^{\circ}$; aLDFA, $93.7-95.2^{\circ}$; mLPFA $113.8-117.3^{\circ}$; mLDFA $99.2-100.5^{\circ}$; mMPTA $96.8-98.5^{\circ}$; mMDTA $89.4-90.7^{\circ}$. The Maltese had a larger anteversion angle than the Poodle and the Yorkshire Terrier and a larger mLPFA than the Poodle. In the comparison between the radiographs and the photographs, significant differences were found in the anteversion angle, mLPFA, mMPTA, and mMDTA. The established normal reference values might be useful for determining whether a valgus or varus deformity of the femur or the tibia is present and if so, the degree of angular correction needed.

Isolation of marine birnavirus from ascidian Halocynthia roretzi, and its relation with tunic softness syndrome (멍게, Halocynthia roretzi에서 분리된 해양버나바이러스의 특성과 물렁증과의 관련성)

  • Song, Jin-Kyung;Yun, Hyun-Mi;Choi, Byeong-Dae;Oh, Myung-Joo;Jung, Sung-Ju
    • Journal of fish pathology
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    • v.22 no.3
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    • pp.229-237
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    • 2009
  • The causative agent for the tunic softness syndrome of the cultured ascidian Halocynthia roretzi from Jan 1999 to Feb 2009 was identified using virus isolation and polymerase chain reaction (PCR). The pathogenicity of the isolated virus MABV UR-1 strain was determined by experimental infection trials. The cytopathic effects was observed in CHSE-214 cell line at a level 5.1% (4/78) in normal ascidian and 1.8% in abnormal ascidian showing tunic softness syndrome signs. MABV gene was detected in 16.8% (18/107) of normal and 13.1% (5/38) of abnormal organisms by PCR. The ratio of MABV isolation and gene detection was similar level in normal and soft tunic diseased ascidian. Based on the VP2/NS junction region sequences, eight strains of virus isolated from ascidian, were included in the same genogroup with MABV which is originally isolated in wide ranges of marine fish and shellfish species. The UR-1 strain caused 60% mortality (36.5% mortality in control group) by immersion infection and 37% mortality (same mortality in control group) in injection infection indicating no significant differences in infected and control groups. These results suggest that ascidian can act as reservoir of the MABV, and this virus is not directly related with the ascidian mortality.