• BMB Reports
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• v.40 no.6
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• pp.986-1001
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• 2007

Cold acclimation improves freezing tolerance in plants. In higher plants, many advances have been made toward identifying the signaling and regulatory pathways that direct the low-temperature stress response; however, similar insights have not yet been gained for simple nonvascular plants, such as bryophytes. To elucidate the pathways that regulate cold acclimation in bryophytes, we used two PCR-based differential screening techniques, cDNA amplified fragment length polymorphism (cDNA-AFLP) and suppression subtractive hybridization (SSH), to isolate 510 ESTs that are differentially expressed during cold acclimation in Physcomitrella patens. We used realtime RT-PCR to further analyze expression of 29 of these transcripts during cold acclimation. Our results show that cold acclimation in the bryophyte Physcomitrella patens is not only largely similar to higher plants but also displays distinct differences, suggests significant alteration during the evolution of land plants.

• Journal of Oriental Neuropsychiatry
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• v.16 no.1
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• pp.129-142
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• 2005

Objectives : This study was to investigate MMPI profile on clinical scales and personality scales of Panic Disorder patients. Methods : Thirty eight Panic Disorder patients and twenty eight normal control were administered the MMPI. Experimental design was done by nonequivalent control group and statistics were crosstabs, chi-square test, ANOVA, t-test and cluster analysis Results and Conclusions : 1. The MMPI clinical scales profile of Panic Disorder patients was neurotic profile of 2-7 type. Panic Disorder patients was elevated the other scales except L, K, Mf and Ma scales for control group. 2. A result of grouping MMPI in Panic Disorder patients, we could classify into 3 different groups. Group 1 is a profile of conversional neurosis. Group 2 is a normal proflie. Group 3 is a proflie of $'{\Lambda}'$ type neurosis. 3. Personality characteristics in Panic Disorder patients was lowed scores in HST, NAR scales, elevated the other scales except ANT scale. Specially in PAG, AVD scales showed high scores.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.1
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• pp.373-376
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• 2015

Background: EVA1A (eva-1 homolog A) is a novel gene that regulates programmed cell death through autophagy and apoptosis. Our objective was to investigate the expression profiles and potential role of EVA1A in normal and neoplastic human pancreatic tissues. Materials and Methods: The expression pattern of EVA1A in normal pancreatic tissue was examined by indirect immunofluorescence and confocal microscopy. Protein levels in paraffin-embedded specimens from normal and diseased pancreatic and matched non-tumor tissues were evaluated by immunohistochemistry. Results: EVA1A colocalized with glucagon but not with insulin, demonstrating production in islet alpha cells. Itwas strongly expressed in chronic pancreatitis, moderately or weakly expressed in the plasma membrane and cytoplasm in pancreatic acinar cell carcinoma, and absent in normal pancreatic acinar cells. Although the tissue architecture was deformed, EVA1A was absent in the alpha cells of pancreatic ductal adenocarcinomas, intraductal papillary mucinous neoplasms, mucinous cystadenomas, solid papillary tumors and pancreatic neuroendocrine tumors. Conclusions: EVA1A protein is specifically expressed in islet alpha cells, suggesting it may play an important role in regulating alpha-cell function. The ectopic expression of EVA1A in pancreatic neoplasms may contribute to their pathogenesis and warrants further investigation.

• The Journal of the Korean Society for Microbiology
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• v.9 no.1
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• pp.41-45
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• 1974

On day 2 after treatment of Lewis rat with 25mg of hydrocortisone, the cell number in the thymus was reduced to less than 10% of the matched control. By day 12 after hydrocortisone treatment the thymic cell population was recovered almost its original value and on day 24 after treatment the number of thymocytes was equivalent to that of normal thymocytes. The density distribution profile of hydrocortisone treated rats as compared with normal rats showed a marked decrease in the denser fraction D while the lighter fractions. (A plus B, and C) showed a considerable proportional increase. The proportion of dead cells in thymus suspension from hydrocortisone treated rats was higher than that from their normal counterparts. On separation, the dead cells accumulated selectively in the pellet and A fraction. The response of the thymocytes from hydrocortisone treated rats to PHA was increased compared to that from normal rats. Among the subpopulations, D fraction, which was relatively unresponsive in normal rats, showed a marked increase in PHA response and C fraction showed some increase in the response.

• The korean journal of orthodontics
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• v.14 no.1
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• pp.7-13
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• 1984

A roentgeno cephalometric comparative study was undertaken to reveal significant differences of craniofacial morphology and growth between unilateral cleft lip and palate and normal individuals. The material for this study consisted 32 subjects with repaired unilateral cleft lip and palate (27 male, 5 female) and 44 normal subjects (22 male, 22 female). The analysis was performed by Coben's method and the measurements were compared by Student's t-test. The following conclusions were obtained. 1. In the UCLP subjects there is definite decrease in midfacial growth, so they showed concave profile. 2. The ramus inclination angle and AR-GO of UCLP subjects are larger than normal subjects. 3. The craniofacial height of UCLP subjects is smaller than normal subjects, especially in midface. 4. The lower part of craniofacial height of UCLP subjects is larger than normal subjects.

• The Journal of Korean Academy of Sensory Integration
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• v.2 no.1
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• pp.1-10
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• 2004

Objective : The purpose of this study were to examine internal reliability and internal validity for Short Sensory Profile(SSP) and to suggest the useful criteria for sensory processing abilities in Korean culture. Methods : The Short Sensory Profile(SSP) was completed by mothers of 304 children typically developing between 3 to 10 years of age in those preschool, kindergarten and elementary school located Seoul and Gyeonggi-do. The total agency for this study was 14 facilities and the period of study was from July, 2002 to June, 2003. Kim Mi Sun(2001) translated and modified the Short Sensory Profile that Macintoshi developed and the tool for the study was used. The data were analyzed with reliability test and Pearson's correlation. Results : 1. Internal reliability of the total tests and sections was estimated by calculating Cronbach's Alphas. Reliability value of the total tests was .889. 2. For internal validity the correlations range from .131 to .575 in magnitude, suggesting that the sections of the Short Sensory Profile tap relatively unique constructs and support the factor structure developed. 3. The total score of the Short Sensory Profile(SSP) range from 118 to 190, mean and SD was 163.12, 14.87. 4. Of 403 children represented by the survey, 32 children(10.5%) met criteria for sensory processing disorders based upon parental perceptions. 5. Cut scores were determined by computing the raw score cut scores for -1 SD and -2 SD. The normal group of sensory processing abilities had score which range from 190 to 149, the probable problem group had score which range from 148 to 134, and the definite problem group had score which range from 133 to 138. Conclusion : Findings from the above study suggest that Short Sensory Profile be the screening tool for sensory processing disorders within Korean culture. Further research is needed to compare with children with the various sensory processing disabilities(PDD, LD, CP ect,).

• Journal of Oriental Neuropsychiatry
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• v.17 no.3
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• pp.67-75
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• 2006

This Study is attempted to analyze Minnesota Multiphasic Personality Inventory responses to Vertigo patients and remedial value of Oriental medicine treatment. Methods: 24 Vertigo patients and 28 control group were tested by MMPI and QSCCII. It is analyzed by cluster analysis, one-way ANOVA, chi-square test, t-test, Duncan method is used as ex-post test. Results and Conclusions: 1. The MMPI scores of Vertigo patients were elevated in Hs, Hy clinical scales, 1-3 profile type, it is profile of conversional neurosis. In this case body condition where the psychological problem will get conversion is a notable feature. 2. All of the profiles can be classified three types of profile. Group 1(33.3%) showed 1-3-2 profile type and elevated Pt. scale, suggesting mainly depressive neurosis in the department of neuropsychiatry. Group 2 (37.5%) showed a normal profile. Group 3(29.2%) showed 1-3 profile type it is profile of conversional neurosis. With this result it is indicated that 62.5% Vertigo patients are related to emotional difficulties. 3. There was to a remedial value for the Vertigo patients, before treating from VAS score 10.00 after treating at VAS score 4.13. From this study, we know the possibility the Oriental medicine register remedial value for the Vertigo patients.

• KSTLE International Journal
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• v.2 no.2
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• pp.85-92
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• 2001

The variation of contact traction induced by different contact shapes is studied experimentally and theoretically. Considerations fer the contact shape are rounded, truncated and truncated with rounding punches. A fretting wear experiment is conducted with the contact configuration of the strip on the tube specimens. The strip specimen is pressed to form the end profile of a rounded and truncated with rounding punches shape. Wear on the tube is investigated, which is regarded as the slip region of the contact surface. Taken into consideration is the general solution of the normal traction in the case of the indentation by a punch with its end profile of the combination of parabolas. Then, partial slip solution is obtained numerically, which is compared with the wear on the tube. The radius of the rounding and the obliquity of the edge truncation affect the tractions considerably. It is found that the proper choice of the end profile can restrain the contact-induced failure such aswear.

• Communications for Statistical Applications and Methods
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• v.7 no.2
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• pp.481-487
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• 2000

When we construct an interval estimate of two independent proportions with rare events, the standard approach based on the normal approximation behaves badly in many cases. The problem becomes more severe when no success observations are observed on both groups. In this paper, we compare two alternative methods of constructing a confidence interval of the difference of two independent proportions by use of simulation. One is based on the profile likelihood and the other is the Bayesian probability interval. It is shown in this paper that the Bayesian interval estimator is easy to be implemented and performs almost identical to the best frequentist's method -the profile likelihood approach.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.11 no.5
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• pp.42-47
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• 2012

Construction equipment is heavily loaded during normal operation. In recent years, there is a trend that lower gear noise levels are demanded for drivers to avoid annoyance and fatigue during operation. For articulated hauler's final drive, meshing transmission error(T.E.) is the excitation that leads the tonal noise known as gear whine, and radiated gear whine is also the dominant source of noise in the whole gearbox. This paper presents a method for the analysis of the tooth profile modification, and the prediction of transmission error under the loaded torques for the spur gear pair of the articulated hauler's final drive. And the transmission error, transmission error harmonics and contact stress are also calculated and compared before and after tooth modification under one torque. The simulation result shows that the transmission error and contact stress under the loads can be minimized by the appropriate tooth profile modification.