• Wind and Structures
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• v.5 no.2_3_4
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• pp.177-192
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• 2002

Computation solutions for the flow around a cube, which were generated as part of the Computational Wind Engineering 2000 Conference Competition, are compared with full-scale measurements. The three solutions shown all use the RANS approach to predict mean flow fields. The major differences appear to be related to the use of the standard $k-{\varepsilon}$, the MMK $k-{\varepsilon}$ and the RNG $k-{\varepsilon}$ turbulence models. The inlet conditions chosen by the three modellers illustrate one of the dilemmas faced in computational wind engineering. While all modeller matched the inlet velocity profile to the full-scale profile, only one of the modellers chose to match the full-scale turbulence data. This approach led to a boundary layer that was not in equilibrium. The approach taken by the other modeller was to specify lower inlet turbulent kinetic energy level, which are more consistent with the turbulence models chosen and lead to a homogeneous boundary layer. For the $0^{\circ}$ case, wind normal to one face of the cube, it is shown that the RNG solution is closest to the full-scale data. This result appears to be associated with the RNG solution showing the correct flow separation and reattachment on the roof. The other solutions show either excessive separation (MMK) or no separation at all (K-E). For the $45^{\circ}$ case the three solutions are fairly similar. None of them correctly predicting the high suctions along the windward edges of the roof. In general the velocity components are more accurately predicted than the pressures. However in all cases the turbulence levels are poorly matched, with all of the solutions failing to match the high turbulence levels measured around the edges of separated flows. Although all of the computational solutions have deficiencies, the variability of results is shown to be similar to that which has been obtained with a similar comparative wind tunnel study. This suggests that the computational solutions are only slightly less reliable than the wind tunnel.

• Journal of Nutrition and Health
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• v.33 no.1
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• pp.59-67
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• 2000

The objective of this study was to investigate nutritional status of middle aged Korean men exhibiting impaired glucose tolerance (IGT) and identify the risk factors related to IGT Data were collected from 163 men with a fasting blood glucose level from 115 to 139mg/dl(high blood glucose group: HBG) and 170 men with a normal fasting blood glucose level(control) aged from 40 to 59 years in both groups. Weight, body mass index(BMI) and percent body fat were significantly higher in high blood glucose(HBG) group than those of control group. Age, weight, BMI, percent body fat were positively related to blood glucose. There were no differences in exercise, smoking and family history of diabetes between two groups. Frequency of fat eating and overeating of HBG were higher than those of control group but frequency of sweet snacks intake of HBG was lower than that of control group. There was no difference in daily total energy intake in two groups. Total and supper energy intakes were positively associated with blood glucose. Percent energy intake of alcohol was significantly higher in HBG group and positively related to blood glucose, however there were no difference in daily intake of nutrients in two groups. Alcohol intake was positively related to BMI, but after adjusting BMI, there was no correlation between alcohol intake and blood glucose. Serum total cholesterol and triglyceride were significantly higher in HBG group than those of control group. Serum total cholesterol i,nd triglyceride were positively related to blood glucose and high density lipoprotein cholesterol was negatively associated with blood glucose. After adjusting BMI, serum triglyceride was positively related to blood glucose. In conclusion, weight, BMI, percent body fat and blood total cholesterol, low density lipoprotein cholesterol and triglyceride levels were positively related to blood glucose level of middle aged Korean men exhibiting impaired glucose tolerance. Their eating habits exhibited higher frequency of overeating, fast eating, high energy intakes of supper. (Korean J Nutrition 33(1) : 59-67, 2000)

• Journal of KIISE:Software and Applications
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• v.36 no.12
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• pp.996-1008
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• 2009

This paper proposes a novel approach for the model-based pose matching of a human body using Active Shape Models. To improve the processing time of model creation and registration, we use a skeleton-type model instead of the conventional silhouette-based models. The skeleton model defines feature information that is used to match the human pose. Images used to make the model are for 600 human bodies, and the model has 17 landmarks which indicate the body junction and key features of a human pose. When applying primary Active Shape Models to the skeleton-type model in the matching process, a problem may occur in the proximal joints of the arm and leg due to the color variations on a human body and the insufficient information for the fore-rear directions of profile normals. This problem is solved by using the background subtraction information of a body region in the input image and adding a 4-directions feature of the profile normal in the proximal parts of the arm and leg. In the matching process, the maximum iteration is less than 30 times. As a result, the execution time is quite fast, and was observed to be less than 0.03 sec in an experiment.

• The Journal of Korean Association of Computer Education
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• v.13 no.6
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• pp.91-98
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• 2010

NAC(Network Access Control) has been developed as a solution for the security of end-point user, to be a target computer of worm attack which does not use security patch of OS and install Anti-Virus, which spreads the viruses in the Intra-net. Currently the NAC products in market have a sufficient technology of pre-connect, but insufficient one of post-connect which detects the threats after the connect through regular authentication. Therefore NAC users have been suffered from Zero-day attacks and malware infection. In this paper, to solve the problems in the post-connect step we generate the normal behavior profiles using the traffic information of each host, host information through agent, information of open port and network configuration modification through network scanner addition to authentication of host and inspection of policy violation used before. Based on these we propose the system to detect the hosts infected malware.

• The Korean Journal of Food And Nutrition
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• v.27 no.4
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• pp.558-569
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• 2014

The quality and characteristics of purple sweet potato sponge cake were studied with the addition of different proportions of purple sweet potato powder depending on storage period The pHs, heights, and weights of doughs were in the ranges of 6.3~6.5, 4.8~4.4 cm and 397~418 g, respectively. The sponge cake groups with the addition of different proportions of purple sweet potato powder showed significantly different characteristics in hardness, adhesiveness, cohesiveness, gumminess, and chewiness, according to texture profile analysis. The difference in colors of sponge cakes with addition with purple sweet potato revealed that L-value and b-value were significantly reduced but a-value especially increased according to the density. Using scanning electron microscopy (SEM), it was confirmed that the stoma size of purple sweet potato sponge cake become smaller and the stoma wall became thicker in proportion to the contents of purple sweet potato powder, which could result in an increased level of water content after a long period pf storage. According with the observations, water content remarkably increased after 4~6 days of storage and the ability to keep water content seemed to contribute to extention the shef-life of sponge cakes. In sensory evaluation, sponge cakes with high contents of purple sweet potato were preferred and cakes with the addition of 25% and 30% purple sweet potato powder was most preferred. It was expected that the shelf-life of purple sweet potato sponge cake was 4 days under the normal temperature.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.11
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• pp.6281-6286
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• 2013

Background: To further investigate the molecular basis of lung cancer development, we utilize a microarray to identify differentially expressed genes associated with various TNM stages of adenocarcinoma, a subtype with increasing incidence in recent years in China. Methods: A 35K oligo gene array, covering about 25,100 genes, was used to screen differentially expressed genes among 90 tumor samples of lung adenocarcinoma in various TNM stages. To verify the gene array data, three genes (Zimp7, GINS2 and NAG-1) were confirmed by real-time RT-PCR in a different set of samples from the gene array. Results: First, we obtained 640 differentially expressed genes in lung adenocarcinomas compared to the surrounding normal lung tissues. Then, from the 640 candidates we identified 10 differentially expressed genes among different TNM stages (Stage I, II and IIIA), of which Zimp7, GINS2 and NAG-1 genes were first reported to be present at a high level in lung adenocarcinoma. The results of qRT-PCR for the three genes were consistent with those from the gene array. Conclusions: We identified 10 candidate genes associated with different TNM stages in lung adenocarcinoma in the Chinese population, which should provide new insights into the molecular basis underlying the development of lung adenocarcinoma and may offer new targets for the diagnosis, therapy and prognosis prediction.

• Journal of Computational Design and Engineering
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• v.2 no.4
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• pp.206-217
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• 2015

This paper presents a complete S-shape feed rate scheduling approach (CSFA) with confined jerk, acceleration and command feed rate for parametric tool path. For a Non-Uniform Rational B-Spline (NURBS) tool path, the critical points of the tool path where the radius of curvature reaches extreme values are found firstly. Then, the NURBS curve is split into several NURBS sub-curves or blocks by the critical points. A bidirectional scanning strategy with the limitations of chord error, normal/tangential acceleration/jerk and command feed rate is employed to make the feed rate at the junctions between different NURBS blocks continuous. To improve the efficiency of the feed rate scheduling, the NURBS block is classified into three types: short block, medium block and long block. The feed rate profile corresponding to each NURBS block is generated according to the start/end feed rates and the arc length of the block and the limitations of tangential acceleration/jerk. In addition, two compensation strategies are proposed to make the feed rate more continuous and the arc increment more precise. Once the feed rate profile is determined, a second-order Taylor's expansion interpolation method is applied to generate the position commands. Finally, experiments with two free-form NURBS curves are conducted to verify the applicability and accuracy of the proposed method.

• Asian-Australasian Journal of Animal Sciences
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• v.30 no.5
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• pp.700-711
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• 2017

Objective: The current study aimed to investigate the impact of high-fat diets composed of different animal and vegetable fat sources on serum metabolic health markers in Japanese quail, as well as the overall lipid content and fatty acid profiles of the edible bird tissues following significantly increased dietary lipid supplementation. Methods: Fifty seven male quail were divided into six groups and fed either a standard diet or a diet enriched with one of five different fats (22% coconut oil, lard, palm oil, soybean oil, or sunflower oil) for 12 weeks. The birds were subjected to an oral glucose tolerance test following the feeding period, after which they were euthanized and blood, liver, breast, and thigh muscle samples collected. Total fat content and fatty acid profiles of the tissue samples, as well as serum uric acid, triglyceride, cholesterol, total protein, albumin, aspartate transaminase, and total bilirubin concentrations were assessed. Results: High-fat diet feeding had no significant effects on the glucose tolerance of the birds. Dietary fatty acid profiles of the added fats were reflected in the lipid profiles of both the liver and breast and thigh muscle tissues, indicating successful transfer of dietary fatty acids to the edible bird tissues. The significantly increased level of lipid inclusion in the diets of the quail used in the present study was unsuccessful in increasing the overall lipid content of the edible bird tissues. Serum metabolic health markers in birds on the high-fat diets were not significantly different from those observed in birds on the standard diet. Conclusion: Thus, despite the various high-fat diets modifying the fatty acid profile of the birds' tissues, unlike in most mammals, the birds maintained a normal health status following consumption of the various high-fat diets.

• Journal of KIISE:Computer Systems and Theory
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• v.30 no.9
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• pp.461-476
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• 2003

Due to the implementation ease and alleviation of memory bottleneck effect, NUMA architecture has dominated in the multiprocessor systems for the past several years. However, because the NUMA system distributes memory in each node, frequent remote memory access is a key factor of performance degradation. Therefore, efficient design of RAC(Remote Access Cache) in NUMA system is critical for performance improvement. In this paper, we suggest Multi-Grain RAC which can adaptively control the RAC line size, with respect to each application behavior Then we simulate NUMA system with multi-grain RAC using MINT, event-driven memory hierarchy simulator. and analyze the performance results. At first, with profile-based determination method, we verify the optimal RAC line size for each application and, then, we compare and analyze the performance differences among NUMA systems with normal RAC, with optimal line size RAC, and with multi-grain RAC. The simulation shows that the worst case can be always avoided and results are very close to optimal case with any combination of application and RAC format.

• Molecules and Cells
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• v.40 no.10
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• pp.737-751
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• 2017

Histone-modifying enzymes are key players in the field of cellular differentiation. Here, we used GSK-J4 to profile important target genes that are responsible for neural differentiation. Embryoid bodies were treated with retinoic acid ($10{\mu}M$) to induce neural differentiation in the presence or absence of GSK-J4. To profile GSKJ4-target genes, we performed RNA sequencing for both normal and demethylase-inhibited cells. A total of 47 and 58 genes were up- and down-regulated, respectively, after GSK-J4 exposure at a log2-fold-change cut-off value of 1.2 (p-value < 0.05). Functional annotations of all of the differentially expressed genes revealed that a significant number of genes were associated with the suppression of cellular proliferation, cell cycle progression and induction of cell death. We also identified an enrichment of potent motifs in selected genes that were differentially expressed. Additionally, we listed upstream transcriptional regulators of all of the differentially expressed genes. Our data indicate that GSK-J4 affects cellular biology by inhibiting cellular proliferation through cell cycle suppression and induction of cell death. These findings will expand the current understanding of the biology of histone-modifying enzymes, thereby promoting further investigations to elucidate the underlying mechanisms.