• 한국컴퓨터정보학회:학술대회논문집
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• 한국컴퓨터정보학회 2019년도 제59차 동계학술대회논문집 27권1호
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• pp.159-160
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• 2019

본 연구에서는 영상 내 도로의 형태와 영상 내 객체들의 속성을 실시간으로 자기 학습하고 영상 전체에서 나타난 객체와 각 도로 차선을 지나는 객체들의 이상 징후를 판별하기 위해 교통 CCTV 영상을 활용한다. 각 도로 구간을 촬영한 교통 영상에서 추출한 이동 객체 로그에서 영상 내 도로 형태와 영상 내 객체들의 속성을 통해 감시 공간을 학습하고 학습된 정상 프로파일 대비 각 차선을 지나는 객체들과 영상 내 객체들의 이상 상황을 실시간에 판별한다.

• Natural Product Sciences
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• 제28권2호
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• pp.62-67
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• 2022

Column chromatographic fractionation of the methanol and ethyl acetate extracts of the stem-bark of Anacardium occidentale led to the isolation of five compounds (1-5). Their structures were determined by spectroscopic means by comparing spectral data to be β-sitosterol (1), 2,4-dihydroxy acetophenone (2), 1-monolinolein (3), ethyl oleate (4) and β-sitosterol-3-O-β-D-glucopyranoside (5). These compounds were evaluated for cytotoxicity against human cancer cell lines: A549, SCOV3 and rat normal cell line NRK49f. Compounds 2-5 were for the first time isolated from A. occidentale.

• 대한치과교정학회지
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• 제47권2호
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• pp.108-117
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• 2017

Objective: To investigate the effects of frontal facial type (FFT) and sex on preferred chin projection (CP) in three-dimensional (3D) facial images. Methods: Six 3D facial images were acquired using a 3D facial scanner (euryprosopic [Eury-FFT], mesoprosopic [Meso-FFT], and leptoprosopic [Lepto-FFT] for each sex). After normal CP in each 3D facial image was set to $10^{\circ}$ of the facial profile angle (glabella-subnasale-pogonion), CPs were morphed by gradations of $2^{\circ}$ from normal (moderately protrusive [$6^{\circ}$], slightly protrusive [$8^{\circ}$], slightly retrusive [$12^{\circ}$], and moderately retrusive [$14^{\circ}$]). Seventy-five dental students (48 men and 27 women) were asked to rate the CPs ($6^{\circ}$, $8^{\circ}$, $10^{\circ}$, $12^{\circ}$, and $14^{\circ}$) from the most to least preferred in each 3D image. Statistical analyses included the Kolmogorov-Smirnov test, Kruskal-Wallis test, and Bonferroni correction. Results: No significant difference was observed in the distribution of preferred CP in the same FFT between male and female evaluators. In Meso-FFT, the normal CP was the most preferred without any sex difference. However, in Eury-FFT, the slightly protrusive CP was favored in male 3D images, but the normal CP was preferred in female 3D images. In Lepto-FFT, the normal CP was favored in male 3D images, whereas the slightly retrusive CP was favored in female 3D images. The mean preferred CP angle differed significantly according to FFT (Eury-FFT: male, $8.7^{\circ}$, female, $9.9^{\circ}$; Meso-FFT: male, $9.8^{\circ}$, female, $10.7^{\circ}$; Lepto-FFT: male, $10.8^{\circ}$, female, $11.4^{\circ}$; p < 0.001). Conclusions: Our findings might serve as guidelines for setting the preferred CP according to FFT and sex.

• 한국식품영양과학회지
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• 제38권1호
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• pp.47-51
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• 2009

비타민 C 섭취 및 요가가 중년 여성의 총항산화능, 지질과 산화 및 혈중지질에 미치는 영향을 알아보기 위하여 B광역시 H구에 거주하는 중년여성을 대상으로 12주간 실험을 실시하였다. 요가 프로그램은 주 3회, 1일 60분, 운동 강도 RPE $13{\sim}15$로 실시하였다. 비타민 C는 1일 1 g을 섭취시켰다. 12주 후 총항산화능의 변화는 정상군 28.23%, 비타민 C군 30%, 요가군 26.58%, 비타민 C 섭취와 요가군은 43.66%가 증가하였으나 군간 유의적인 차이가 없었다. 지질과산화물가의 변화는 정상군 10%, 비타민 C군 -25%, 요가군은 -32.14%, 비타민 C 섭취와 요가군은 -33.87%로 정상군에 비해 프로그램군이 유의적으로 감소하였으나 프로그램군간의 유의적인 차이는 없었다. 혈중지질농도 변화는 모든군에서 유의적인 차이가 없어 요가 또는 비타민 C 섭취에 따른 지질개선효과를 관찰할 수 없었다. 이상의 결과를 통해 중년여성에게 비타민 C 섭취나 규칙적인 요가 프로그램은 지질과산화물가를 낮춤으로써 체내 산화적 스트레스를 개선하는 효과가 있는 것으로 생각된다.

• 대한소아치과학회지
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• 제30권2호
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• pp.298-307
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• 2003

측모두부방사선 사진은 임상적으로 쉽게 드러나지 않은 치아와 골격간의 상세한 관계를 나타내주며, 이것을 계측 분석하는 다양한 방법들이 소개되어 임상에 적용되고 있다. 이 중 Kim's analysis는 수직피개(overbite)의 지표로 ODI(Overbite Depth Indicator), 전후방적 부조화의 지표로 APDI(Anteroposterior Dysplasia Indicator). 그리고 이들의 합인CF(Combination Factor)를 제시하였다. 또 CF에 상하악의 절치각과 안모의 돌출도를 고려하여 EI(Extraction Index)를 산출하였다. 이러한 분석법에 이용되는 각 계측치들이 정상교합자와 III급 부정교합자에서 어떻게 분포하며 어떤 차이를 보이는가를 조사하기 위해 본 연구를 시행하였다. 골격이 조화로우며 안모가 단정한 7세부터 9세의 정상교합자와 동일한 연령의 III급 부정교합자 141명의 아동을 대상으로 하여 Kim's analysis에 이용되는 계측항목들을 통계적으로 분석하여 다음과 같은 결과를 얻었다. 1. 정상교합자와 III급부정교합자의 비교에서 ODI, APDI, IIA, UL은 유의한 차이를 보였으나, CF와 EI는 통계적인 유의차가 없었다(P<0.01). 2. 정상교합자에서 ODI, APDI, IIA의 평균은 각각 72.63, 80.47, 121.37이었다. 3. III급 부정교합자 ODI, APDI, IIA의 평균은 각각 64.46, 87.31, 129.80이었다. 4. ODI와 APDI의 Pearson 상관계수는 -0.576으로 역상관관계를 나타내었다. 5. EI와 다른 계측치들간의 상관관계는 CF(0.777), LL(-0.607), UL(-0.588), IIA(0.485), APDI(0.444), ODI(0.304)의 순서였다. 이것은 발치분석을 하는데 있어 상순과 하순의 돌출도가 가장 민감하게 반영된다는 것을 암시한다.

• Molecular & Cellular Toxicology
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• 제1권1호
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• pp.62-71
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• 2005

For toxicity model in the kidney, renal cell carcinoma (RCC) is one of the most important model to assess the structural and functional alterations. Most RCCs are sporadic, and environmental agents are suspected to play a role in the etiology of the disease. In this study, we discovered novel evidence for previously unknown gene expression patterns related to progression according to cancer stage in RCC. Four clear cell RCC tissue samples along with five corresponding patient-matched normal kidney tissue samples were obtained from patients undergoing partial or radical nephrectomy. To examine the difference of gene expression profile in clear cell RCC, radioactive cDNA microarrays were used to evaluate changes in the expression of 1,152 genes in a total. Using $^{33}P-labeled$ probes, this method provided highly sensitive gene expression profiles including drug metabolism, and cellular signaling. 29 genes were identified with expression levels that differed by more than 2.0 value of z-ratio, compared with that in control. Whereas expression of 38 genes were decreased by less than-2.0 value of z-ratio. In conclusion, this study has identified 67 gene expression alterations in clear-cell type of RCC. Most notably, genes involved in cell growth were up-regulated in stage I more than stage III whereas genes involved in signal transduction were down-regulated in which both stage I and stage III. The identified alteraions of gene expression will likely give in sight in to clear cell RCC and tumor progression.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제18권2호
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• pp.108-114
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• 2015

Purpose: The aim of this study is to evaluate the relationship between abdominal subcutaneous fat thickness measured by ultrasonography (US) and serum lipid profile and liver transaminases in obese children. Methods: One hundred and sixty-six children diagnosed with obesity from May 2001 to December 2013 were included in this study. Data on serum lipid profile and liver transaminases were collected from clinical records. Abdominal subcutaneous fat thickness and grade of hepatic steatosis were evaluated by US. Results: Of the 166 children, 107 were diagnosed with hepatic steatosis by US, 46 with grade I, 56 with grade II, and five children with grade III. According to the grade of hepatic steasosis, the average values of midline abdominal subcutaneous fat thickness and right flank abdominal subcutaneous fat thickness measured $2.9{\pm}0.8cm$ and $1.9{\pm}0.7cm$ in the normal group, $3.3{\pm}0.8cm$ and $2.0{\pm}0.7cm$ in grade I, $3.8{\pm}0.8cm$ and $2.3{\pm}0.8cm$ in grade II, and $4.1{\pm}0.8cm$ and $2.8{\pm}1.4cm$ in grade III, respectively. Abdominal subcutaneous fat thickness correlated with grade of hepatic steatosis (p<0.01). In addition, abdominal subcutaneous fat thickness correlated with concentration of serum lipids and liver transaminases in the age group of 12-14 years (p<0.01). Conclusion: Abdominal subcutaneous fat thickness measured by US can be used as a reliable predictor of possible hyperlipidemia and steatohepatitis in children, especially during the adolescent stage.

• 대한한방내과학회지
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• 제31권4호
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• pp.706-713
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• 2010

Objectives : The source is from the flower of Carthamus tinctorius L., family Compositae. It is used in clinical medicine to promote blood circulation, remove blood stasis, promote menstruation and alleviate pain. In the present study, we investigated the genome wide analysis of Carthami Flos on the intra-cranial hemorrhage(ICH) model. Methods : ICH in rat was induced by injection of collagenase type IV and Carthami Flos extract(CFe) was administered orally. The molecular profile of cerebral hemorrhage in rat brain tissue was measured using microarray technique to identify up- or down- regulated genes in brain tissue. Results : Expression profile showed that diverse genes were up- or down-regulated by ICH induction. Administration of CFe restored the expression level of some of altered genes by ICH to normal expressional level. Interestingly, these recovered genes by CFe were involved in the same biological pathways which were significantly activated or suppressed by ICH. Conclusion : The above results might explain the therapeutic mechanism of CFe on ICH. Further, by analyzing interaction network, core genes was identified which could be key molecular targets of CFe against ICH.

• 대한한방소아과학회지
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• 제21권2호
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• pp.153-167
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• 2007

Objetives This experimental study is designed to investigate the effects of kwakhyangjungkisangamibang extract on the changes of adipose tissues, serum insulin and leptin levels in rats induced by a high fat diet. The leptin has been proposed to be involved in the role of food intake and energy expenditure. Methods During the 8 weeks of experimental period, male Sprague-Dawley rats were fed on the 2 different diets: the normal diet AIN-76A and high fat(beef tallow) diet ad libitum, of which 40% of the calories intake was fat. 9 rats in the control and high fat diet group were killed for the baseline experiment at 4 weeks of age. The high fat diet group was divided into three groups: control group, experimental group I(high fat diet plus kwakhyangjungkisangamibang extract), and experimental group II(high fat diet plus mahuang). The body weight, hypodermal fat tissue, serum lipid profile, insulin and leptin levels were measured after the administration of the high fat diet and extract. Results 1. The body weight was decreased in experimental group II, but there was not a significance difference compared to the control group. 2. The peritoneal, visceral, and hypodermal adipose tissue was decreased in experimental group I, but there was not a significance difference compared to the control group. 3. The lipid profile was decreased in experimental group I, but not in group II. 4. The insulin concentration was increased in experimental group I and II, but there was not a significance difference compared to the control group. 5. The leptin level was increased significantly in experimental group I(p<0.05) and II(p<0.01) compared to the control group. Conclusion The results of this study indicate that kwakhyangjungkisangamibang has an effect on the regulation of obesity.

• Nutrition Research and Practice
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• 제2권3호
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• pp.158-164
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• 2008

This study investigated that the antioxidative effect of freeze-dried cranberry powder against protein and lipid oxidation and ameliorative effect of serum lipid profile in rat fed atherogenic diet. Six weeks old male Sprague-Dawley rats were divided into the following four groups: normal diet group with 5% com oil(control), atherogenic diet group with 5% com oil, 10% lard, 1% cholesterol, and 0.5% sodium cholate(HFC), atherogenic plus 2% cranberry powder diet group(HFC+C2), and atherogenic plus 5% cranberry powder diet group(HFC+C5), and respective diet and water were fed daily for 6 weeks. After the experimental period, the serum lipid profile, such as total cholesterol, HDL-cholesterol, LDL-cholesterol, and triglyceride, ferric reducing ability of plasma(FRAP), plasma phenolics content, superoxide dismutase(SOD) activity, serum protein carbonyl and thiobarbituric acid reactive substances(TBARS) levels were examined. Total phenolic compound and total flavonoid levels in freeze-dried cranberry powder were 9.94 mg/g and 8.12 mg/g, respectively. Serum total cholesterol and LDL-cholesterol levels were not significantly different for cranberry powder treatment, but serum HDL-cholesterol level was significantly increased in HFC+C5 group compared with HFC group. Plasma FRAP value tended to be increased by cranberry powder treatment though there was no significant difference. Plasma total phenol concentrations and SOD activities were not significantly different among all groups. Serum protein carbonyl and TBARS levels were significantly decreased in HFC+C5 group compared with HFC group. Overall results suggested that freeze-dried cranberry powder might have the serum lipid improving effect, as well as anti oxidative effect demonstrated by its protective effect against protein and lipid oxidation.