• Journal of Digital Convergence
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• v.13 no.11
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• pp.471-479
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• 2015

In this study, we measured lung function and lung diffusing capacity of Jeju women divers who were gathering activities in the sea waters of the low temperature. The results Compared with ordinary women of the same age group were as follows: First, FVC and FVC% of Jeju women divers were significantly higher than the general population. Second, $FEV_1/FVC$ had no significant difference the difference between the general population and Jeju women divers. Third, $FEF_{25{\sim}75%}$ in both groups was in the normal level, especially Jeju women divers groups showed significantly higher FEF results than normal women. Fourth, DLCO is no significant difference between the Jeju divers and the general female group. Despite the advanced age of Jeju women divers These results indicated that adaptation and development of state institutions while performing long-term lung apnea immersion activities. Despite the advanced age of Jeju women divers These results indicated that adaptation and development of state institutions while performing long-term lung apnea immersion activities.

• Development and Reproduction
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• v.16 no.4
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• pp.353-361
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• 2012

Human embryonic stem (ES) cells are a potential source of cells for developmental studies and for a variety of applications in transplantation therapies and drug discovery. However, human ES cells are difficult to culture and maintain at a large scale, which is one of the most serious obstacles in human ES cell research. Culture of human ES cells on MEF cells after disassociation with accutase has previously been demonstrated by other research groups. Here, we confirmed that human ES cells (H9) can maintain stem cell properties when the cells are passaged as single cells under a feeder-free culture condition. Accutase-dissociated human ES cells showed normal karyotype, stem cell marker expression, and morphology. We prepared frozen stocks during the culture period, thawed two of the human ES cell stocks, and analyzed the cells after culture with the same method. Although the cells revealed normal expression of stem cell marker genes, they had abnormal karyotypes. Therefore, we suggest that accutase-dissociated single cells can be usefully expanded in a feeder-free condition but chromosomal modification should be considered in the culture after freeze-thawing.

• Archives of Plastic Surgery
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• v.34 no.6
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• pp.705-712
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• 2007

Purpose: Transsexualism is considered to be the extreme end of the spectrum of gender identity disorders characterized by, among other things, a pursuit of sex reassignment surgery (SRS). We evaluated psychologic status, health-related quality of life in female-to-male (FTM), male-to-female (MTF) transgender individuals. Methods: We used the Minnesota Multiphasic Personality Inventory, Beck Anxiety Inventory, Beck Depression Inventory, Moudsley obsessive-compulsive Inventory, SCL-90-R, Short-Form 36-Question Health Survey version 2 (SF-36v2). We enrolled 40 transsexual participants. Results: Analysis of quality of life health concepts demonstrated statistically significant (p<0.01) diminished quality of life among the transsexual participants as compared to the Korea male and female population. FTM transgender participants reported more higher hostile, phobic than MTF transgenders. Overall, in all psychologic status examination, Transgender individuals are within normal population boundary. On all category, result is improved post-operatively. Conclusion: Transgender participants reported mental status within normal boundary. SRS improved their quality of life and mental stability.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.11 no.1
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• pp.42-50
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• 2000

This study was designed to evaluate the emotional and behavioral problems of nocturnal enuresis children(n=72) in general population. And this was compared with normal control children(n=72). The behavioral problems were assessed using a modified child behavior checklist(CBCL) parent form. The results indicated that enuretic children were rated significantly more anxious, fearful, depressed, inattentive, hyperactive, delinquent on the modified CBCL rating when compared to the age-, grade- and sex-matched normal control children. Finally, it was an impressive evidence that there exist many emotional and behavioral problems in children with nocturnal enuresis.

• The Bulletin of The Korean Astronomical Society
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• v.37 no.1
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• pp.31.2-31.2
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• 2012

We present the Yonsei Evolutionary Population Synthesis (YEPS) models for spectroscopic and photometric evolutions of simple and composite stellar populations. The models are based on the most up-to-date Yonsei-Yale stellar evolutionary tracks and BaSel 3.1 flux libraries, and provide integrated spectroscopic quantities of Lick/IDS system including high-order Balmer absorption-lines. Special care has been taken to incorporate the systematic variation of horizontal branch (HB) morphology as functions of metallicity, age, alpha-element mixture, and helium abundance of simple stellar populations. Our models for normal-helium stellar populations indicate that the realistic modeling of HB and alpha-element brings about 5 Gyr and 0.1 dex differences in age and metallicity estimations, respectively, compared to those without these effects. The HB effect does not depend on the specific choice of stellar libraries and alpha-element enhancements, and this effect is non-negligible even in the metal sensitive absorption indices, such as Mg2 and Mg b. Comparison of the models to observations reveals that the HB and alpha-element effects are critical in understanding otherwise inexplicable phenomena found in globular cluster systems in the Milky Way and nearby galaxies, including the observed bimodality of the line strengths of globular clusters in massive galaxies. In addition, we found that helium-enhanced stellar populations, which are the major sources of extreme HB stars, bring about increased FUV, NUV fluxes, and thus the model colors of those filters become extremely blue. Age dating based on the YEPS model with normal-helium stellar populations reveals that the evidence for 'downsizing' of elliptical galaxies is found not only in the local field but also in Coma cluster, and that the mean age of elliptical galaxies in Coma cluster is about 1.4 Gyr younger than the mean age of those in the local field. We also find that our models with helium-enhanced subpopulations can naturally reproduce the strong UV-upturns observed in giant elliptical galaxies assuming an age similar to that of old GCs in the Milky Way.

• Korean Journal of Biological Psychiatry
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• v.16 no.3
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• pp.149-158
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• 2009

Objectives : This study was designed to investigate the association of schizophrenia and P1320, P1325, P1635, P1655, P1763 and SNP A polymorphisms on dystrobrevin binding protein 1(DTNBP1) gene in Korean patients. Methods : We analyzed P1320, P1325, P1635, P1655, P1763 and SNP A polymorphisms on DTNBP1 gene from their DNAs extracted from their blood in 388 Korean schizophrenic patients (male 198, female 190) and 372 control subjects(male 247, female 125). We compared the differences of genotype and allele distributions of the six polymorphisms on DTNBP1 gene between the Korean schizophrenic patient group and the normal control group. Results : There were no statistically significant differences of genotype and allele distributions of the P1320, P1325, P1635, P1655, P1763 and SNP A polymorphisms on DTNBP1 gene between the schizophrenic patient group and the normal control group. Conclusion : The results of this study suggest that P1320, P1325, P1635, P1655, P1763 and SNP A polymorphism on DTNBP1 gene do not have influence on the risk of the schizophnenic in the Korean population.

• Restorative Dentistry and Endodontics
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• v.20 no.1
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• pp.235-249
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• 1995

This study was designed to identify the lymphocytes present and to examine the relation between lymphocytes population and clinical symptoms of the pulps clinically diagnosed as normal and irreversible pulpitis. We recorded the history and severity of the pain and performed several clinical tests, before extirpation of vital, irreversibly inflamed pulps in routine endodontic treatment. Then the teeth were divided into two groups. Five teeth, categorized in acute symptom group, had severe spontaneous pain, particularly at night and were extremely sensitive to cold and heat. The other 15 teeth with history of mild to moderate pain and with or without cold or heat responses were categorized as chronic symptom group. Inflamed pulps were also classified into 8 minor groups by presence or absence of signs or symptoms related to the involved teeth, including the presence of pain on percussion, pain on heat and cold stimuli and the periodontal pocket depth. All extirpated pulps were immediately immersed in ultra low-temperature freezer($-74^{\circ}C$), and they were sectioned $6{\mu}m$ in thickness. Specimens were stained using three-stage indirect immunoperoxidase techniques(DAKO, LSAB kit) and monoclonal antibodies for detecting the presence of T lymphocytes(T), B lymphocytes(B) and helper(T4) and suppressor(T8) lymphocytes. Following results were obtained; 1. All the examined normal and inflamed pull) tissues had positive staining for T lymphocytes and T helper and T suppressor cells. But B cells were observed only in inflamed pulp. 2. Statistically more T and B cells were observed in acute symptom group as compared with chronic symptom group(p<0.05). 3. Cell ratio of BIT in acute symptom group were significantly higher than that of chronic symptom group(p<0.05). 4. Only B cells were significantly increased in the percussion positive group than the number of B cells in percussion negative group(p<0.05). 5. No differences were observed in the number of different cell types among other minor groups.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.3
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• pp.546-550
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• 2011

The aim of this study was to evaluate oriental medicine pattern identification in patients with stroke on the basis of plasma fibrinogen levels and platelet counts. 555 patients diagnosed with stroke between November 2006 and February 2010 were divided in several ways according to the plasma fibrinogen levels and platelet counts on admission. And comparative analysis of the distribution ratio of oriental medicine pattern identification was done between the groups. The mean value of the plasma fibrinogen levels of whole population was 449.18 mg/dL, and it was higher than normal range. The mean value of the platelet counts of whole population was 244.29 /mL, and it was lower but in normal range. Oriental medicine pattern identifications were not characteristic between groups divided according to the serum levels of fibrinogen and platelet counts. In this study, there was not significant correlation between Oriental medicine pattern identifications and the thrombotic factor like plasma fibrinogen levels and platelet counts. This study could be the steppingstone for the next study to develope the objective indicator for the Oriental medicine pattern identifications.

• Journal of Life Science
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• v.14 no.2
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• pp.345-350
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• 2004

The present study was investigated microgeographic variations to spatial autocorrelation in the Korean alder, Alnus hirsuta. Separate counts of each type of join (combination of genotypes at a single locus) for each allele, and for each distance class of separation, were tested for significant deviation from random expectations by calculating the Standard Normal Deviation (SND). Moran's I was significantly different from the expected value in 24 of 120 cases (20.0%). 17 of these values (14.2%) were significantly negative, indicating genetic dissimilarity among pairs of individuals in the ten distance classes. Many Korean populations of alder are small and are distributed by men for firewood. This occasional cutting of seed-bearing stems may bring a high level of gene flow. In addition, stump sprouting ability also may contribute to the fact that the Chengkwang population at Gijang is unusual in lacking spatial genetic structure.

• Journal of Korean Biological Nursing Science
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• v.19 no.4
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• pp.266-275
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• 2017

Purpose: The purpose of this study was to investigate the influences of sarcopenic and non-sarcopenic obesity on the components of Metabolic Syndrome (MetS) in adolescents. Methods: This study used the fifth Korean National Health and Nutrition Examination Survey data from 2010 to 2011. The study included 859 adolescents aged 12 to 18 years. Descriptive statistics and simple and multiple logistic regression analyses were conducted using SAS 9.2. Results: Based on the results, adolescents with sarcopenic obesity had a higher risk of central obesity (AOR: 23.41, 95% CI: 12.76-43.97), high triglyceride (OR: 4.58, 95% CI: 2.69-7.79), low HDL-cholesterol (AOR: 2.66, 95% CI: 1.74-4.05), high blood pressure (AOR: 3.44, 95% CI: 1.37-8.68), and high fasting glucose (AOR: 2.37, 95% CI: 1.13-4.96) than their normal counterparts. Adolescents with non-sarcopenic obesity had a higher risk of central obesity (AOR: 19.75, 95% CI: 9.73-44.67), high triglyceride (OR: 3.09, 95% CI: 1.22-7.81), and low HDL-cholesterol (AOR: 2.73, 95% CI: 1.37-5.45) than normal youths, and these were not significantly related to high blood pressure and fasting glucose. Conclusion: Sarcopenic obesity was more related to the components of MetS than non-sarcopenic obesity. Since adolescents with sarcopenic obesity are a more vulnerable population, a prevention and management program for MetS and cardiovascular risk should be implemented in this population.