• Journal of Pharmacopuncture
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• v.11 no.1
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• pp.83-97
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• 2008

Objectives : We investigated the effects of distilled Rehmannia glutinosa Herbal Acupuncture on autonomic nervous system with the Heart Rate Variability(HRV) in adult man. as well as we tried to observe how distilled Rehmannia glutinosa Herbal Acupuncture on the balance of the autonomic nervous system. Methods : We investigated on 58 healthy volunteers consisted of 28 subjects in experiment(distilled Rehmannia glutinosa Herbal Acupuncture) group and 30 subjects in control(Normal Saline) group. Study form was a randomized, placebo-controlled, double-blind clinical trial. 28 subjects in experiment group were injected distilled Rehmannia glutinosa Herbal Acupuncture at $GB_{21}$(Kyonjong) and 30 subjects in control group were injected Normal Saline at $G_{21}$(Kyonjong). except of 2 subjects(in control group) who can't be measured and 6 subjects(2 in experiment group and 4 in control group) who move or make unforceable error during measuring. Finally 26 subject in experiment group and 24 subject in control group are studied. We measured HRV by PolyG-I on 7 times : before and after injection per 5 minutes during 30 minutes. The SPSS 10.0 for windows was used to analyze the data and the paired t-test(in group) and Student t-test(between two groups) were used to verify the result. Results : 1. After distilled Rehmannia glutinosa Herbal Acupuncture injection, Mean HRV is significantly low only for first 5 minute, SDNN is significantly high after 5 minute, Complexity is significantly low only from 20 minute to 25 minute. HRV index is significantly high for first 5minute and from 10 minute to after 10 minute. 2. HRV index of distilled Rehmannia glutinosa Herbal Acupuncture Group significantly increased from 25 minute to 30 minute, and pNN50 of Rehmannia glutinosa Herbal Acupuncture Group significantly decreased from 20 minute to 30 minute compared with those of Normal Saline group. 3. After distilled Rehmannia glutinosa Herbal Acupuncture injection, Ln(TP) and Ln(VLF) are significantly high after injection. Normalized LF is significantly high from 5 minute to 20 minute and from 25 minute and 30 minute. Normalized HF is significantly low from 5minute to 20 minute and from 25 minute and 30 minute. 4. Ln(TP) and Ln(VLF) of distilled Rehmannia glutinosa Herbal Acupuncture Group significantly increased from 20 minute to 25 minute compared with those of Normal Saline group. Conclusions : The results suggest that Rehmannia glutinosa Herbal Acupuncture in healthy adult man tend to activate the autonomic nervous system and parasympathetic nervous system compared to Normal Saline within normal range.

• The korean journal of orthodontics
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• v.10 no.1
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• pp.45-53
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• 1980

This study was based on the study models of 32 subjects with normal occlusion, 40 with Class I malocclusion, 32 with Class II, Division 1 malocclusion and 38 with Class III malocclusion, aged 12 to 20 years (mean age 16.4 years). The purpose of present study was to define the difference between normal and malocclusion groups in maxillary dental arch and palate. On the basis of findings of this study, the following results were obtained. 1. The intermolar widths and the intercanine widths in Class II, Div. 1 malocclusion group were smaller than in normal occlusion group significantly. 2. The arch lengths measured in both Class I and Class II, Div.1 malocclusion groups were larger than in normal occlusion group. 3. The palates in Class I and Class II, Div. 1 malocclusion groups were longer and narrower than in normal occlusion, but the palates in Class III malocclusion group were shorter than in normal occlusion group significantly. 4. The palatal depths measured at level 1 in Class III malocclusion group were significantly higher than in normal occlusion and in Class II, Div. 1 group they were significantly higher than in normal occlusion at level 2 and 3. 5. The measurements of palatal areas at various levels showed no significant difference between malocclusion and normal occlusion groups. 6. The palatal indies 1 (palatal length / palatal width) measured in both Class I and Class II, Div. 1 malocclusion groups were significantly greater than in normal occlusion and the palatal indice 2 (palatal depth at level 1/palatal width) measured in all malocclusion groups are greater than in normal occlusion. 7. It was determined from findings of this study that the measurements of maxillary dental arch and palate were influenced to a considerable extent by the molar relationship.

• Journal of Navigation and Port Research
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• v.42 no.6
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• pp.446-452
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• 2018

A traffic route is an area associated with high risk for accidents due to the flow of heavy traffic. Despite this concern, most studies related to traffic focus solely on traffic distribution. Therefore, there is a need for studies investigating the characteristics of ships' routes and traffic patterns. In this study, an investigation was carried out to analyze the traffic distribution and pattern in 3 major traffic routes for 3 days. For the purpose of the study, based on the prevailing traffic conditions, the route was divided into 10 gate lines. The ships passing through the lines were also classified into either small, medium and large. ND-K-S (normal distribution, kurtosis, and skewness) test was carried out for the traffic distribution at each gate line based on the information analyzed on each traffic route. The analysis of the results obtained from the ND test showed that large vessels have normal distribution, medium sized vessels have satisfied normal distribution in one-way route only while small sized vessels do not have normal distribution. According to the result obtained from the K-S test, normal traffic pattern shows a significant difference between two-way route and one-way route. Results obtained from the K test result shows that in the case of one-way route, vessels have a traffic pattern using a wide range on traffic route. Further analysis shows that vessels concentrate on one side of route in case of two-way route. Results obtained from the S test show that, in case of one-way route, vessels have a normal traffic pattern according to center line. However, analysis pf the results shows that vessels are shifted to the right side of route in case of two-way route. Despite these findings, it should be noted that this study was carried out in only 3 ports, therefore there is need for investigation to be carried out in various routes and conditions in future studies.

• Food Science of Animal Resources
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• v.34 no.3
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• pp.263-272
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• 2014

The effect of the addition of Allium hookeri on the quality of fermented sausage made with meat from sulfur fed pigs was examined, throughout a 60 d ripening period. There were two treatments in animal management: normal feed fed pigs, and sulfur fed pigs given 0.3% sulfur mixed normal feed. Fermented sausage manufactured with meat from normal feed fed pigs, and with meat from sulfur fed pigs, and 1% A. hookeri-containing fermented sausage processed with meat from sulfur fed pigs, were determined at 1 d, 15 d, 30 d, and 60 d. The meat qualities in fermented sausage were measured by DPPH radical scavenging activity (DPPH), $ABTS^+$ radical scavenging activity ($ABTS^+$), total phenolic acids, and total flavonoid contents. Fermented sausage made from pigs that had been fed with 0.3% sulfur was protected from oxidation by reduced free radical, as shown by the significant increase in DPPH and $ABTS^+$ values, compared with fermented sausage made from normal feed fed pigs (p<0.05). A. hookeri-added fermented sausage with sulfur fed pork was shown to increase the values in DPPH, $ABTS^+$, total phenolic acid, and total flavonoid contents, by comparison with both the control sausage, and sausage with sulfur fed pork, at 60 d. These results suggest that A. hookeri in meat from sulfur fed pigs could be a source of natural addition, to increase quality in the food industry.

• Parasites, Hosts and Diseases
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• v.53 no.6
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• pp.789-793
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• 2015

In order to explore tick proteins as potential targets for further developing vaccine against ticks, the total proteins of unfed female Dermacentor silvarum were screened with anti-D. silvarum serum produced from rabbits. The results of western blot showed that 3 antigenic proteins of about 100, 68, and 52 kDa were detected by polyclonal antibodies, which means that they probably have immunogenicity. Then, unfed female tick proteins were separated by 12% SDS-PAGE, and target proteins (100, 68, and 52 kDa) were cut and analyzed by LC-MS/MS, respectively. The comparative results of peptide sequences showed that they might be vitellogenin (Vg), heat shock protein 60 (Hsp60), and fructose-1, 6-bisphosphate aldolase (FBA), respectively. These data will lay the foundation for the further validation of antigenic proteins to prevent infestation and diseases transmitted by D. silvarum.

• Journal of Biomedical Engineering Research
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• v.25 no.2
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• pp.129-135
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• 2004

In the home health management system, we often face the situation to handle biological signals that are frequently measured from normal subjects. In such a case, it is necessary to decide whether the signal at a certain moment is normal or abnormal. Since ECC is one of the most frequently measured biological signals, we describe algorithms that detect QRS-complex and decide whether it is normal or abnormal. The developed QRS detection algorithm is a simplified version of the conventional algorithm providing enough performance for the proposed application. The developed classification algorithm that detects abnormal from mostly normal beats is based on QRS width, R-R interval and QRS shape parameter using Karhunen-Loeve transformation. The simplified QRS detector correctly detected about 99% of all beats in the MTT/BIH ECG database. The classification algorithm correctly classified about 96% of beats as normal or abnormal. The QRS detection and classification algorithm described in this paper could be used in home health management system.

• The korean journal of orthodontics
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• v.18 no.1 s.25
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• pp.89-104
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• 1988

This study was performed to investigate the relationships between the EMG activity of the masticatory muscles in Angle's Class II div. 1 malocclusion and normal occlusion. This study was ranged from age 12 to 14 year-old for 30 male subjects: 15 subjects were Angle's Class II div. 1 malocclusion, and 15 subjects were normal occlusion with acceptable profile. Their cephalometric measurement were analyzed, and the EMG recordings from the anterior temporal, posterior temporal, masseter, and orbicularis oris muscles were analyzed during rest position, mastication of peanuts, and swallowing. All data was recorded and statistically processed with the VAX-11/780 computer system. The results were as follows: 1. The activity of muscles at rest was highest in the posterior temporal muscle with normal occlusion, as well as in those with Class II div. 1 malocclusion, and the posterior temporal muscle activity of Class II div. 1 malocclusion was higher than that of normal occlusion. 2. During mastication, all muscle activities of Class II div. 1 malocclusion were recorded lower than those of normal occlusion, and the activity of the anterior temporal muscle was higher than that of the posterior temporal muscle in both types of occlusion. 3. As for the activity in orbicularis oris muscle, it was greater in opening phase than in closing phase during chewing cycle with both types of occlusion. 4. During swallowing, the activities of the anterior temporal, masseter, and orbicularis oris muscles of Class II div. 1 malocclusion were recorded lower than those of normal occlusion.

• Journal of Ginseng Research
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• v.46 no.1
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• pp.23-32
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• 2022

Panax polysaccharides are biopolymers that are isolated and purified from the roots, stems, leaves, flowers, and fruits of Panax L. plants, which have attracted considerable attention because of their immunomodulatory activities. In this paper, the composition and structural characteristics of purified polysaccharides are reviewed. Moreover, the immunomodulatory activities of polysaccharides are described both in vivo and in vitro. In vitro, Panax polysaccharides exert immunomodulatory functions mainly by activating macrophages, dendritic cells, and the complement system. In vivo, Panax polysaccharides can increase the immune organ indices and stimulate lymphocytes. In addition, this paper also discusses the membrane receptors and various signalling pathways of immune cells. Panax polysaccharides have many beneficial therapeutic effects, including enhancing or activating the immune response, and may be helpful in treating cancer, sepsis, osteoporosis, and other conditions. Panax polysaccharides have the potential for use in the development of novel therapeutic agents or adjuvants with beneficial immunomodulatory properties.

• Bulletin of the Korean Chemical Society
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• v.33 no.9
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• pp.2961-2965
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• 2012

Mesoporous carbons with tailored pore size were prepared by using sucrose as the carbon source and silicas as the templates. The silica templates were obtained from a hydroxypropyl-${\beta}$-cyclodextrin-silica hybrids using ammonium perchlorate oxidation at different temperatures to remove the organic matter. The structures and surface chemistry properties of these carbon materials were characterized by $N_2$ adsorption, TEM, SEM and FTIR measurements. The catalytic performances of these carbon materials were investigated through the reduction of nitroaromatic using hydrazine hydrate as the reducing agent. Compared with other carbon materials, such as active carbon, and carbon materials from the silica templates obtained by using calcination to remove the organic matter, these carbon materials exhibited much higher catalytic activity, no obvious deactivation was observed after recycling the catalyst four times. Higher surface area and pore volume, and the presence of abundant surface oxygen-containing functional groups, which originate from the special preparation process of carbon material, are likely responsible for the high catalytic property of these mesoporous carbon materials.

• Bulletin of the Korean Chemical Society
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• v.31 no.2
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• pp.379-383
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• 2010

Metabolites of colorectal cancer tissues from 12 patients were analyzed and compared with those of the normal tissues by two-dimensional NMR spectroscopy. NMR data were analyzed with the help of the metabolome database and the statistics software. Cancerous tissues showed significantly altered metabolic profiles as compared to the normal tissues. Among such metabolites, the concentrations of taurine, glutamate, choline were notably increased in the cancerous tissues of most patients, and those of glucose, malate, and glycerol were decreased. Changes in individual metabolites varied significantly from patient to patient, but the combination of such changes could be used to distinguish cancerous tissues from normal ones, which could be done by PCA analysis. The traditional chemometric analysis was also performed using AMIX software. By comparing those two results, the analysis via $^1H-^{13}C$ HSQC spectra proved to be more robust and effective in assessing and classifying global metabolic profiles of the colorectal tissues.