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Effect of Tributyltin Chloride on Survival, Growth and Reproduction in Zebra Fish Danio rerio

  • Balasubramani, A.;Pandian, T.J.
    • 한국양식학회지
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    • 제21권3호
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    • pp.146-156
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    • 2008
  • Tributyltin chloride(TBTCl) was administered through discrete immersion(2 hr each) from the $18^{th}-25^{th}$ day after hatching(dph). At the doses of 1, 2, 4 and 8 ${\mu}g/L$, the immersion at 2 ${\mu}g/L$ ensured 93% masculinization and the highest survival of 75% after the treatment. TBTCl acted as a growth suppressant and the magnitude of its suppression was stronger in females. During the 300 day experiment, it postponed sexual maturity of females from 120$^{th}$ dph in the control to 240$^{th}$ dph in the females treated at 8 ${\mu}g/L$. It reduced spawning frequency(22-3 times) and cumulative fecundity(1,632-19 eggs) by reducing the number of vitellogenic eggs. In the treated males too, it reduced sperm motility(100-68 sec); consequently, fertilizability of the sperm cells drawn from these males was also reduced from 88 to 43%. Progeny testing showed that the cross between males treated at>2 ${\mu}g/L$ and normal females generated the presumed 'homogametic' males. Both the treated 'homogametic' and 'heterogametic' males could induce the females to spawn fewer eggs than that of the normal males. A normal female somehow deducted the differences between the control, treated and sex reversed males; it preferred a normal male over a treated one, and a treated one over the sex reversed male.

인삼이 칼슘결핍 흰쥐골격근의 소포체에 의한 칼슘 - Uptake에 미치는 영향 (The Effect of Ginseng on the Calcium Uptake by Sarcoplasmic Reticulum Fragments Isolated from Potassium Deficient Rat Skeletal Muscles)

  • 김낙균;김낙두;이종욱
    • 약학회지
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    • 제30권3호
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    • pp.143-148
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    • 1986
  • The effect of orally administered ginseng ethanol extract on potassium deficient and normal rat skeletal muscles was investigated in terms of Ca uptake by sarcoplastic reticulum fragments. The ginseng ethanol extract (100mg/kg/day) was administered orally to Sprague-Dawley rats for 21 days and their changes of body weights, $K^+$ content in skeletal muscles, and calcium uptake capacity of sarcoplamic reticulurn of each groups were measured. The growth rate of rats fed with the potassium deficient diet was significantly decreased compared to that of normal rats. Ginseng components did not show any effect on the decreased growth rate of the postassium deficient rats. Potassium content in skeletal muscle from potassium deficient rats was significantly reduced compared to that of normal rats. Ginseng components showed the tendency to prevent the reduction in potassium content of potassium deficient rats, but differences were not statistically significant. Calcium uptake of SR prepared from skeletal muscles of potassium deficient rats was increased significantly compared to that of normal rats. Ginseng components prevented such increase of calcium uptake by 30%. In summary, it can be concluded that ginseng may prevent the increase in Cauptake of SR obtained from potassium deficient rats.

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Effects of Glucuronic Acid Derivative Isolated from Xylan on Antioxidative Defense System in Rat Red Gastrocnemius after Aerobic Exercise

  • Kim, Mi-Ji;Rhee, Soon-Jae
    • Nutritional Sciences
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    • 제6권3호
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    • pp.135-140
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    • 2003
  • The purpose of this study was to investigate the effects of glucuyonic acid (isolated from xylan) on the antioxidative defense systems of red gastrocnemius in rats after aerobic exercise. The glucuronic acid was isolated from xylan. Male Sprague-Dawley vats weighing 150$\pm$10 g were randomly assigned to one normal group and three exercise training groups. The exercise training groups were classified as T (glucuronic acid-free diet), TU (250mg glucuronic acid/kg bw) and 2TU (500mg glucuronic acid /kg bw) according to the level of glucuvonic acid supplementation. The rats in the normal group were confined to a cage for 4 weeks. The rats in the exercise training groups ran on a treadmill for 30 min/day, 5 days/week at a speed of 28 m/min (7% incline) for 4 weeks. Glutamate oxaloacetate transaminase (GOT) activity in the exercise training groups increased significantly compared with that of the normal group. That of the TU and 2TU groups decreased significantly compared with that of the T group. Xanthine oxidase (XOD) activity in the T group increased significantly to 74% compared with that of the normal group. That of the 2TU group decreased to 42% compared with that of the T group, thus recovering to a normal level. Superoxide dismutase (SOD) activity in the T group decreased to 32% compared with that of the normal group. That of the TU and 2TU groups increased to 28% and 34%, respectively, compared with that of the T group. Glutathione peroxidase (GSHpx) activity in the T group decreased to 16% compared with that of the normal group, but that of the TU group increased to 17% compared with that of the T group. Glutathiones transferase (GST) activity in the T group decreased to 11% compared with that of the normal group, but that of the TU and 2TU groups Increased to 28% and 31%, respectively, compared with that of the T group. The contents of thiobarbituric acid reactive substances (TBARS) in the T group increased to 81% compared with that of the normal group, but the glucuronic supplementation group recovered to the normal level. In conclusio, the effects of glucuronic acid on red gastrocnemius in rats engaged in exercise training would appear to be to reduced lipid peroxidation of tissue as an antioxidative defense mechanism.

안드로이드 모바일 정상 및 악성 앱 시스템 콜 이벤트 패턴 분석을 통한 유사도 추출 기법 (Normal and Malicious Application Pattern Analysis using System Call Event on Android Mobile Devices for Similarity Extraction)

  • 함유정;이형우
    • 인터넷정보학회논문지
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    • 제14권6호
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    • pp.125-139
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    • 2013
  • 안드로이드 기반 오픈 마켓의 개방성으로 인해 일반적인 정상 어플리케이션 뿐만아니라 공격자에 의해 개발된 악성 어플리케이션의 배포 역시 점차 증가하고 있는 추세이다. 악성 어플리케이션들의 확산으로 인한 피해를 줄이기 위해서는 상용 모바일 단말을 대상으로 보다 정확한 방법으로 정상 앱과 악성 앱을 판별할 수 있는 메커니즘이 개발되어야 한다. 이에 본 논문에서는 안드로이드 플랫폼 기반 모바일 단말을 대상으로 정상 앱과 악성 앱으로 부터 이벤트 패턴을 분석하기 위해 안드로이드 오픈 마켓에서 가장 사용자 이용도가 높은 게임 앱을 대상으로 정상 이벤트 패턴을 분석하였고, Android MalGenome Project에서 배포하고 있는 1,260개의 악성 샘플들 중에서 게임 앱 형태에 해당하는 악성 앱과 유사 악성 앱 등을 대상으로 악성 이벤트 패턴을 분석하였다. 이와 같이 안드로이드 기반 모바일 단말에서 정상 앱과 악성 앱을 대상으로 리눅스 기반 시스템 콜 추출 도구인 Strace를 이용해 정상 앱과 악성 앱의 이벤트를 추출하는 실험을 수행하였다. 정상 앱 및 악성 앱이 각각 실행되었을 때 발생하는 이벤트를 수집하여 각각의 이벤트 집합에 대한 연관성 분석 과정을 수행하였다. 이러한 과정을 통해 정상 앱과 악성 앱 각각에 대한 이벤트 발생 특징 및 패턴과 분포도를 분석하여 이벤트 유사도를 추출할 수 있었으며 최종적으로는 임의의 앱에 대한 악성 여부를 판별하는 메커니즘을 제시하였다.

MEVVA ion Source And Filtered Thin-Film Deposition System

  • Liu, A.D.;Zhang, H.X.;Zhang, T.H.;Zhang, X.Y.;Wu, X.Y.;Zhang, S.J.;Li, Q.
    • Journal of Korean Vacuum Science & Technology
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    • 제6권2호
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    • pp.55-57
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    • 2002
  • Metal-vapor-vacuum-arc ion source is an ideal source for both high current metal ion implanter and high current plasma thin-film deposition systems. It uses the direct evaporation of metal from surface of cathode by vacuum arc to produce a very high flux of ion plasmas. The MEVVA ion source, the high-current metal-ion implanter and high-current magnetic-field-filtered plasma thin-film deposition systems developed in Beijing Normal University are introduced in this paper.

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Polynomially Adjusted Normal Approximation to the Null Distribution of Ansari-Bradley Statistic

  • Ha, Hyung-Tae;Yang, Wan-Youn
    • 응용통계연구
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    • 제24권6호
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    • pp.1161-1168
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    • 2011
  • The approximation for the distribution functions of nonparametric test statistics is a significant step in statistical inference. A rank sum test for dispersions proposed by Ansari and Bradley (1960), which is widely used to distinguish the variation between two populations, has been considered as one of the most popular nonparametric statistics. In this paper, the statistical tables for the distribution of the nonparametric Ansari-Bradley statistic is produced by use of polynomially adjusted normal approximation as a semi parametric density approximation technique. Polynomial adjustment can significantly improve approximation precision from normal approximation. The normal-polynomial density approximation for Ansari-Bradley statistic under finite sample sizes is utilized to provide the statistical table for various combination of its sample sizes. In order to find the optimal degree of polynomial adjustment of the proposed technique, the sum of squared probability mass function(PMF) difference between the exact distribution and its approximant is measured. It was observed that the approximation utilizing only two more moments of Ansari-Bradley statistic (in addition to the first two moments for normal approximation provide) more accurate approximations for various combinations of parameters. For instance, four degree polynomially adjusted normal approximant is about 117 times more accurate than normal approximation with respect to the sum of the squared PMF difference.

사춘기전(思春期前) 아동(兒童)의 정상(正常) 비강(鼻腔) 통기도(通氣度)에 관한 연구(硏究) (A STUDY ON NORMAL NASAL RESPIRATORY RESISTANCE IN THE PREPUBERTAL CHILDREN)

  • 양원식;서정훈;남동석;장영일
    • 대한치과교정학회지
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    • 제22권1호
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    • pp.31-42
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    • 1992
  • This study was designed to analyze normal nasal respiratory resistance in prepubertal children. The subjects consisted of 30 prepubertal children (male: 15, female: 15). The mean age was 11.4 years in male children and 11.5 years in female children. The results were as follows: I. The normal nasal respiratory patency was lower than the normal values from RION corp. 2. The normal nasal respiratory airflow rates showed no sexual differences. And there were no differences between inspiration and expiration. 3. Before and after use of nasal decongestants, there were no significant differences of normal nasal respiratory airflow rates and after the administration of nasal decongestants, nasal respiratory patency manifested lower variability. 4. The normal nasal respiratory resistance without nasal decongestants at 150 Pascal in inspiration was $0.30Pa/cm^3/sec({\pm}0.07)$ and peak nasal inspiratory airflow rate was $1016.83cm^3/sec({\pm}223.89)$. 5. The normal nasal respiratory resistance with nasal decongestant at 150 Pascal in inspiration was $0.25Pa/cm^3/sec({\pm}0.05)$ and peak nasal inspiratory airflow rate was $1148.33cm^3/sec({\pm}234.29)$.

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Adhesion of clay to metal surface; Normal and tangential measurement

  • Basmenj, Amir Khabbazi;Ghafoori, Mohammad;Cheshomi, Akbar;Azandariani, Younes Karami
    • Geomechanics and Engineering
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    • 제10권2호
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    • pp.125-135
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    • 2016
  • Adhesion in geotechnical engineering is the interaction between cohesive soil and a solid surface which can cause clogging in mechanized tunnelling through clayey formations. Normal piston pull out and modified direct shear tests were performed on clayey soil samples to determine which type of adhesion stress, normal or tangential, could be most effectively measured. Measured values for normal adhesion ranged from 0.9 to 18 kPa. The range of tangential adhesion was 2.4 to 10 kPa. The results indicate normal adhesion results were more accurate than those for the modified direct shear test that measure tangential adhesion. Direct shear test on identical samples did not show any correlation between measured cohesion and normal adhesion values. Normal adhesion values have shown significantly meaningful variation with consistency index and so are compatible with the base of field clogging assessment criteria. But tangential adhesion and cohesion were not compatible with these assessment criteria.

정상홍삼과 불량홍삼의 화학적 특성 (Chemical Characteristics of Normal and Inferior Parts in Korean Red Ginseng)

  • 김천석;이종원;도재호
    • Journal of Ginseng Research
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    • 제25권2호
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    • pp.89-93
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    • 2001
  • This study was carried out to investigate a point of difference in chemical characteristics between normal and inferior Korean red ginseng (Naeback red ginseng=red ginseng with white part of clear boundary in phloem and/or xylem of ginseng body, saengnaeback red ginseng=red ginseng with white part of indistinct boundary). content of total sugar as chemical components of naeback and saengnaeback part from Korean red ginseng were less than that of normal part, and content of reducing sugar in normal and saengnaebakc part showed higher than that of naeback part. But differences in content of total phenolic compounds was not found. The content of crude saponin in normal part was highest, amounts of ginsneoside were about same. The content of constituent amino acid in normal part was about 2 times as compared with those in naeback and saengnaeback part in red ginseng. Among the various amino acids, the contents of arginine, glutamic acid, aspartic acid, leucine and alanine of normal and naeback part were higher than others, but in saengnaeback proline, glutamic acid, aspartic acid, threonin and glycine etc. were higher. In the total amount of free amino acids, those in normal, naeback and saengnaeback part were about the same one another, and arginine, glutamic acid and aspartic acid were major free amino acids.

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담배(Nicotiana tabacum) 세포배양에 의한 Glyphosate-저항성 개체의 재분화 (Regeneration of Glyphosate-Resistant Plant from Tobacco (Nicotiana tabacum) Cell Culture)

  • 최상봉
    • Journal of Plant Biology
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    • 제30권1호
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    • pp.69-77
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    • 1987
  • From the single cell cultures of haploid tobacco (Nicotiana tabacum L. cv. NC 2326) glyphosate-resistant plants were regenerated. After treated with N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and then inoculated onto the LS medium supplemented with 1 mM glyphosate, the single cells survived formed colonies and calluses in 65 and 95 days after culture, respectively, and then whole plants were regenerated in 0.1 mM glyphosate-containing medium from the selected calluses. There was no difference in fresh weight and shikimate content between the selected and normal haploid calluses. When sprayed with 0.1 mM glyphosate, the shikimate contents in the regenerated and normal plants were 0.659 and 20.816 mol/g fr. wt., while that in other normal plants which were not sprayed was 0.921. In addition, the calluses induced from the regenerated plants grew without showing any retardation when treated with glyphosate. These results indicate that the secelcted calluses and regenerated plants are resistant to glyphosate.

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