• Title/Summary/Keyword: nonparametric tests

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Information Dissemination During the COVID-19 Pandemic in Bangladesh

  • Sayed, Abu;Haque, Md. Ziaul;Mahmud, Md. Rifat
    • Journal of Information Science Theory and Practice
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    • v.10 no.4
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    • pp.66-86
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    • 2022
  • The main aim of this study is to identify the role of information dissemination on urban and rural citizens of Bangladesh during the COVID-19 pandemic and the role of misinformation in this process. The study also aimed at finding appropriate counter misinformation strategies regarding COVID-19. An online questionnaire was prepared to collect the viewpoints of the urban and rural citizens of Bangladesh regarding dissemination of information during COVID-19, misinformation regarding COVID-19, and counter misinformation strategies. Along with demographic and general information, a five-point Likert scale was used to measure COVID-19 related misinformation beliefs and how to counter them. Chi square tests were used to determine the association between current residency, information sources, the importance of information dissemination, reactions after getting COVID related information, and evaluative steps after getting information and before disseminating it. Additionally, nonparametric Mann-Whitney U and Kruskal-Wallis tests were conducted to know the significance of difference in respondents' assessment on COVID-19 related misinformation in terms of their demographic characteristics. Cronbach's alpha score was obtained to see the reliability of the questionnaire items. The current study reveals that both urban and rural citizens of Bangladesh are influenced by information dissemination regarding COVID-19 and they have lower level of misinformation belief. The respondents have differences in misinformation belief by different demographic groups. Respondents' educational status, information literacy, sources of getting information, and evaluative steps after getting information have significant differences in misinformation belief. The study also noticed the support of respondents for countering misinformation strategies regarding COVID-19.

Relationship between sonorheometry parameters and laboratory values in a critical care setting in Italy: a retrospective cohort study

  • Antonio Romanelli;Renato Gammaldi;Alessandro Calicchio;Salvatore Palmese;Antonio Siglioccolo
    • Journal of Trauma and Injury
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    • v.36 no.3
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    • pp.210-216
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    • 2023
  • Purpose: This preliminary retrospective cohort study analyzed the relationship between the parameters provided by sonorheometry device Quantra and the coagulation values obtained from standard venous blood samples in patients admitted in intensive care unit (ICU). Methods: We reviewed medical charts of 13 ICU adult patients in whom at least one coagulation study with Quantra was performed. The relationship between Quantra and laboratory data was analyzed with the Spearman rank correlation coefficient (rho). The 95% confidence interval (CI) was computed. A P-value <0.05 was considered statistically significant. Results: We collected 28 data pairs. Statistically significant moderate correlations were found for the following parameters: clot time (CT) and activated partial thromboplastin time (rho=0.516; 95% CI, 0.123-0.904; P=0.009; clot stiffness (CS) and the international normalized ratio (INR; rho=0.418; 95% CI, 0.042-0.787; P=0.039); INR and platelet contribution to CS (rho=0.459; 95% CI, 0.077-0.836; P=0.022); platelet count and platelet contribution to CS (PCS; rho=0.498; 95% CI, 0.166-0.825; P=0.008); and fibrinogen and fibrinogen contribution to CS (FCS; rho=0.620; 95% CI, 0.081-0.881; P=0.001). Conclusions: Quantra can provide useful information regarding coagulation status, showing modest correlations with the parameters obtained from laboratory tests. During diffuse bleeding, CT and FCS values can guide the proper administration of clotting factors and fibrinogens. However, the correlation of INR with CS and PCS can cause misinterpretation. Further studies are needed to clarify the relationship between Quantra parameters and laboratory tests in the critical care setting and the role of sonorheometry in guiding targeted therapies and improving outcomes.

Analysis of the Factors Influencing the Management Characteristics of Tech SMEs in Determination of High-growth Firms: Focusing on Fourth Industrial Revolution Related Businesses and General SMEs (기술 중소기업의 경영 특성에 대한 고성장 기업 결정 영향 요인분석: 4차 산업혁명기업과 일반 중소기업을 중심으로)

  • Yoon, Sun-jung;Seo, Jong-hyen
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.16 no.6
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    • pp.157-175
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    • 2021
  • This study categorized 3,214 companies out of the tech firms supported by the Korea Technology Finance Corporation's "technology guarantee scheme" through technology assessment from 2017 to 2019 into Fourth Industrial Revolution-related companies and general SMEs. The impact of the management characteristics of these 1,752 tech firms on the determination of high-growth firms was then empirically analyzed. This study used the OECD(2007) definition to define a "high-growth firm" as "an enterprise with average revenue growth greater than 20% per annum, over a two-year period." As the two sample groups showed non-normal distribution, this study conducted the Mann-Whitney U test, a nonparametric test, to analyze the mean differences and bivariate logistic regression in which the normality assumption is less stringent. The independent variables include fundamental characteristics; a regional dummy; a technological level dummy; and the capabilities of company representatives, human capital, and technological innovation. The corresponding sub-variables are representatives' level of education and experience in the same industry, full-time workers, research personnel, the extent of intellectual property rights, investment in research and development, firm age, total assets, region_metropolitan area, region_central region, technological level_high technology, and technological level_medium technology. As a result, the research hypothesis about representatives' level of experience in the same industry, full-time workers, total assets, and technological level_high technology was supported for the Fourth Industrial Revolution-related companies. For the general SMEs, the research hypothesis about representatives' level of experience in the same industry, research personnel, total assets, and region_metropolitan area was supported.

A Derivation of Rainfall Intensity-Duration-Frequency Relationship for the Design of Urban Drainage System in Korea (우리나라 도시배수시스템 설계를 위한 확률강우강도식의 유도)

  • Lee, Jae-Jun;Lee, Jeong-Sik
    • Journal of Korea Water Resources Association
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    • v.32 no.4
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    • pp.403-415
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    • 1999
  • This study is to derive the rainfall intensity formula based on the representative probability distribution in Korea. The 11 probability distributions which has been widely used in hydrologic frequency analysis are applied to the annual maximum rainfall. The parameters of each probability distribution are estimated by method of moments, maximum likelihood method and method of probability weighted moments. Four tests such as $x^2$-test, Kolmogorv-Smirnov test, difference test and modified difference test are used to determine the goodness of fit of the distributions. The homogeneous tests (Mann-Whitney U test, Kruskal-Wallis one-way analysis of variance of nonparametric test) are applied to find the stations with rainfall homogeneity. The results of homogeneous tests show that there is no representative appropriate distribution for the whole duration in Korea. The whole region could be divided into five zones for 12-durations. The representative probability distribution of each divided zone for 12-durations was determined. The GEV distribution for I,II,V zones and the 3-parameter Weibull distribution for III,IV zones were determined as the representative probability distribution. The rainfall were obtained from representative probability distribution for the selected return periods. Rainfall intensity formula was determined by linearization technique for the rainfall.

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A Comparative Analysis of Face-to-face and Non-face-to-face Education Based on the Mock Test for a Radiologist (방사선사면허 시험 대비 모의고사 중심으로 대면 교육과 비대면 교육비교 분석)

  • Kim, Yong Wan;Ahn, Beyung Ju;Lee, Jun Heang;Kim, Ju Mi;Yeo, Hwa Yeon
    • Journal of the Korean Society of Radiology
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    • v.14 no.7
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    • pp.923-930
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    • 2020
  • The COVID-19 crisis inevitably led to full-scale non-face-to-face education in 2020. The researchers selected five universities out of 48 universities in radiology and radiology departments nationwide (1.2 in 2019 and 1.2 in 2020) to examine the results of face-to-face training and non-face-to-face mock tests conducted by senior students in radiology departments and radiology departments of the national health department (12 in 2019 and 1.2 in 2020) in preparation for the license test. It turned out to be. Comparing the results of face-to-face and non-face-to-face training (two in 2019 and two in 2020), statistics were analyzed by nonparametric tests, and the results showed that there were differences in theory (Z=-2.023, p<0.05, application (Z=-2.023), p<0.05), practical skills (Z=-1.753, and p<0.05). As a result of the mock test, non-face-to-face education results in poor grades compared to face-to-face education, it is believed that lectures should be taught differently or various educational methods that can communicate with students should be combined.

Predictive Factors Determining Neoadjuvant Chemotherapy Outcomes in Breast Cancer - a Single Center Experience

  • Yu, Yang;Xiang, Hua;He, Xiang-Ming;Yang, Hong-Jian;Zong, Xiang-Yun
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.4
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    • pp.2401-2406
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    • 2013
  • From January 1, 2008 to March 31, 2010, 101 patients with stage II-III breast cancer were enrolled in this study and subjected to an anthracycline-based neoadjuvant chemotherapy regimen with or without docetaxel. Surgery was performed after 2-6 cycles of chemotherapy, and the clinical response was determined by pathological and histochemical assessments. The clinical response rate, as indicated by complete response (CR), partial response (PR), stable disease (SD), and progressive disease (PD), were 6.9, 52.5, 36.6, and 4.0%, respectively. A multivariable correlation analysis indicated that the overall clinical response rate correlated with the number of metastatic lymph nodes, number of chemotherapy cycles, and vessel invasion status. Importantly, the CR rate was only associated with the number of chemotherapy cycles. Nonparametric tests failed to detect a correlation between HER2 or Topo $II{\alpha}$ status and clinical response to neoadjuvant chemotherapy in these patients. When they were stratified by HER2 or HR status, for HER2-positive patients the CR rate was associated with vessel invasion and Topo $II{\alpha}$ status. Based on our findings, we propose that HR, HER-2 and Topo $II{\alpha}$ are not putative predictive biomarkers of chemotherapy outcome for breast cancer patients. Topo $II{\alpha}$ expression level was only inversely correlated with CR rate among HR-positive patients. Importantly, the achievement of CR was largely related to the number of chemotherapy cycles.

Effect of missing values in detecting differentially expressed genes in a cDNA microarray experiment

  • Kim, Byung-Soo;Rha, Sun-Young
    • Bioinformatics and Biosystems
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    • v.1 no.1
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    • pp.67-72
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    • 2006
  • The aim of this paper is to discuss the effect of missing values in detecting differentially expressed genes in a cDNA microarray experiment in the context of a one sample problem. We conducted a cDNA micro array experiment to detect differentially expressed genes for the metastasis of colorectal cancer based on twenty patients who underwent liver resection due to liver metastasis from colorectal cancer. Total RNAs from metastatic liver tumor and adjacent normal liver tissue from a single patient were labeled with cy5 and cy3, respectively, and competitively hybridized to a cDNA microarray with 7775 human genes. We used $M=log_2(R/G)$ for the signal evaluation, where Rand G denoted the fluorescent intensities of Cy5 and Cy3 dyes, respectively. The statistical problem comprises a one sample test of testing E(M)=0 for each gene and involves multiple tests. The twenty cDNA microarray data would comprise a matrix of dimension 7775 by 20, if there were no missing values. However, missing values occur for various reasons. For each gene, the no missing proportion (NMP) was defined to be the proportion of non-missing values out of twenty. In detecting differentially expressed (DE) genes, we used the genes whose NMP is greater than or equal to 0.4 and then sequentially increased NMP by 0.1 for investigating its effect on the detection of DE genes. For each fixed NMP, we imputed the missing values with K-nearest neighbor method (K=10) and applied the nonparametric t-test of Dudoit et al. (2002), SAM by Tusher et al. (2001) and empirical Bayes procedure by $L\ddot{o}nnstedt$ and Speed (2002) to find out the effect of missing values in the final outcome. These three procedures yielded substantially agreeable result in detecting DE genes. Of these three procedures we used SAM for exploring the acceptable NMP level. The result showed that the optimum no missing proportion (NMP) found in this data set turned out to be 80%. It is more desirable to find the optimum level of NMP for each data set by applying the method described in this note, when the plot of (NMP, Number of overlapping genes) shows a turning point.

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Correlation between femoral rotation and clinical results after high tibial osteotomy in primary osteoarthritis patient (퇴행성 골관절염 환자에서 시행한 근위 경골 절골술 후 대퇴골의 회전과 임상결과의 상관관계)

  • Park, Sang Eun;Mun, Sang Won
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.10 no.2
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    • pp.100-104
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    • 2011
  • The purpose of this article is to examine correlation between femoral rotational angle and subjective satisfaction of high tibial osteotomy outcome of the range of motion of knee joint. The subjects were 15 patients (6 males, 9 females) with primary osteoarthritis undergoing high tibial osteotomy from June of 2004 to August of 2008. They were CT tested on the knee joint before and after high tibial osteotomy. TEA (Fig. 1) and Akagi's line (Fig. 2) are analyzed as percentages. The Kendall's and Spearman's nonparametric correlation coefficient were used for the statistical tests with 0.5 level of significance. The result reveals that femoral rotational angle correlates with not the range of motion of knee joint but subjective satisfaction of the patients. Therefore, this will enable patients and physicians to have better clinical outcome.

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Chemical Water Quality and Fish Component Analyses in the Periods of Before- and After-the Weir Constructions in Yeongsan River

  • Kwak, Sang Do;Choi, Ji-Woong;An, Kwang-Guk
    • Journal of Ecology and Environment
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    • v.39 no.1
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    • pp.99-110
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    • 2016
  • The objective of this study was to analyze chemical water quality, ecological characteristics of fish compositions, and ecosystem health before- (Bwc; 2008-2009) and after-the weir construction (Awc; 2011-2012) at Juksan Weir and Seungchon Weir of Yeongsan River watershed. Suspended solids (SS) and chlorophyll-a (Chl-a) in Juksan Weir increased, whereas nutrients such as total nitrogen (TN) and total phosphorus (TP) decreased in the epilimnetic water. In Juksan and Seungchon weirs, fish species distribution analysis in the periods of Bwc and Awc showed that sensitive species were rare and tolerant species were dominant in the community. In the analysis of trophic guild, relative abundance of carnivore species are increased to 22% and 12%, respectively, after the constructions of Seungchon Weir and Juksan Weir. Mann-Whitney U-tests of nonparametric statistical analysis indicated that omnivore and carnivore species had significant differences (p < 0.05) between the Bwc and Awc. The massive population growth of an exotic species, Micropterus salmoides, was evident in Seungchon Weir to influence on the structures of fish communities. The model values of mean Index of Biological Integrity (IBI), based on fish assemblages, were < 15, which indicates "poor" condition in the river health, and the significant difference of IBI values was not found between the Bwc and Awc.

Comparative evaluation of NovaMin desensitizer and Gluma desensitizer on dentinal tubule occlusion: a scanning electron microscopic study

  • Joshi, Surabhi;Gowda, Ashwini Shivananje;Joshi, Chintan
    • Journal of Periodontal and Implant Science
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    • v.43 no.6
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    • pp.269-275
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    • 2013
  • Purpose: In this study, the effect of calcium sodium phosphosilicate (NovaMin) desensitizing agent, which is a powder-based system, and hydroxyethyl methacrylate and glutaraldehyde (Gluma desensitizer), which is liquid-based system, on dentinal tubule occlusion was analyzed by scanning electron microscope. The effects of the above two along with one control group were compared to determine the more effective method of sealing the dentinal tubules after initial application. Methods: Twenty specimens were allocated to each of 3 groups: Control, Gluma desensitizer, and NovaMin. Two additional samples were also prepared and treated with Gluma and NovaMin; these samples were longitudinally fractured. The specimens were prepared from extracted sound human premolars and were stored in 10% formalin at room temperature. The teeth were cleaned of gross debris and then sectioned to provide one to two dentin specimens. The dentin specimens were etched with 6% citric acid for 2 minutes and rinsed in distilled water. Control discs were dried, and the test discs were treated with the desensitizing agents as per the manufacturer's instructions. The discs as well as longitudinal sections were later analyzed under the scanning electron microscope. The proportions of completely occluded, partially occluded, and open tubules within each group were calculated. The ratios of completely and partially occluded tubules to the total tubules for all the groups was determined, and the data was statistically analyzed using nonparametric tests and statistical significance was calculated. Results: NovaMin showed more completely occluded tubules ($0.545{\pm}0.051$) while Gluma desensitizer showed more partially occluded tubules ($0.532{\pm}0.075$). The differences among all the groups were statistically significant ($P{\leq}0.05$). Conclusion: Both materials were effective in occluding dentinal tubules but NovaMin appeared more promising in occluding tubules completely after initial application.