• 전기학회논문지
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• 제56권8호
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• pp.1514-1520
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• 2007

Currently, the signal of the human body is measured with various methods, and a noninvasive investigation of various methods is useful diagnosis method. PTT(Pulse Transit Time) which is noninvasive investigation make use of to estimate the physiological phenomena. PTT has a latent information of cardiovascular system. So we have the experiments for analysis of the relations between PTT and physiological parameters. We examine to correlate to the physiological parameters, an age and degree of paralysis on the ultrasound therapy. The 40 patients who has a such paralysis join our experiment, and we obtain the PTT data that normal condition and states after ultrasound therapy. We study that PTT after the ultrasound therapy for patients who have a paralysis was related to an age and degree of paralysis.

• 한국표면공학회:학술대회논문집
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• 한국표면공학회 2007년도 춘계학술발표회 초록집
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• pp.9-10
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• 2007

본 논문에서는 비접촉식 이온에너지 해석 방법(Noninvasive Ion Energy Analysis, NIEA)을 이용하여 이온에너지 분포함수를 계산하고, 이 분포의 정보를 몇 가지 양으로써 특성지을 수 있는 모니터링 인자를 제안 하였다. 이온 에너지 분포에 영향을 미치는 외부 조건들인 rf 전력, 압력, 전극 간격을 변화시키며 해당 에너지 분포함수의 형태 변화 및 모니터링 인자들의 변화 양상을 관찰 하였다. NIEA 방법으로 측정한 이온 에너지와 공정과의 연관성을 알아보기 위해 poly silicon etching을 수행하며 이온 에너지 분포를 측정하였으며, 이온 에너지와 etch rate이 같은 경향을 나타내는 것을 확인 하였다.

• Archives of Plastic Surgery
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• 제48권2호
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• pp.149-157
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• 2021

Scars vary from mature linear scars to abnormal excessive scars such as hypertrophic scars and keloid scars. Keloid scars are fibro-proliferative disease entities that reflect an abnormal process of wound healing. They can cause pain, itching, stiffness, and psychological distress, all of which can affect quality of life. Various treatment options have been advocated as ways to prevent and treat keloid scars. These include noninvasive treatments such as use of silicone gel sheeting and compression therapy, and invasive treatments such as intralesional corticosteroid injections, surgery, and radiotherapy. Novel treatments include chemotherapy, immunotherapy, and anti-inflammatory therapies. Unfortunately, keloids continue to pose a significant challenge due to the lack of efficacious treatments. Therefore, clinicians should be familiar with various therapeutic options and apply the most suitable treatment plan for patients. In this review, we introduce the current therapeutic options for the management of keloid scars.

• Annals of Clinical Neurophysiology
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• 제24권2호
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• pp.53-58
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• 2022

Noninvasive stimulation of the nervous system for treating chronic neuropathic pain has received attention because of its tolerability and relative efficacy. Repetitive transcranial magnetic stimulation (rTMS) is a representative method of noninvasive brain stimulation. Evidence-based guidelines on therapeutic use of rTMS have been proposed recently for several neurological diseases. These guidelines recommend treating neuropathic pain by applying high-frequency (≥ 5 Hz) rTMS to the primary motor cortex contralateral to the painful side. This review summarizes the mechanisms and guidelines of rTMS for treating neuropathic pain, and proposes directions for future research.

• 순환기질환의공학회:학술대회논문집
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• 순환기질환의공학회 2006년도 제6회 학술대회
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• pp.38-39
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• 2006

• 한국광학회:학술대회논문집
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• 한국광학회 2008년도 동계학술발표회 논문집
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• pp.331-332
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• 2008

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.220.3-221
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• 2002

• 한국광학회:학술대회논문집
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• 한국광학회 2002년도 제13회 정기총회 및 2002년도 동계학술발표회
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• pp.240-241
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• 2002

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2018년도 춘계학술대회
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• pp.184-187
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• 2018

뇌경색의 예방 및 치료에 있어서 가장 중요한 요소는 대뇌 혈류량을 증가시키는 것이다. 대뇌 혈류를 증가시키는 방법으로는 기본적으로 약물에 의한 방법과 수술 또는 동맥 내에 의료 기구를 직접 삽입하는 침습적인 시술(NeuroFloTM) 등이 있다. 본 논문에서 제안하는 비 침습적인 대뇌 혈류 증가 장치는 합병증 유발 확률이 적고, 환자의 혈압 상태에 따라 치료 수준을 정할 수 있으므로 환자의 부담을 덜어줄 수 있다. 이러한 비 침습적인 대뇌 혈류 증가 장치 구현에 있어, 환자에게 알맞은 치료 수준을 제공하기 위한 정확한 평균 동맥압 값을 측정하는 것이 중요하다. 따라서 노이즈를 제거하기 위해 아날로그 필터 및 디지털 필터를 사용하였고, 피크 값 검출을 위한 알고리즘, 펌프제어 알고리즘 등을 사용하였다.

• Journal of Genetic Medicine
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• 제12권2호
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• pp.85-91
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• 2015

Purpose: Noninvasive prenatal test (NIPT) by massively parallel sequencing (MPS) of cell-free fetal DNA in maternal plasma marks a significant advancement in prenatal screening, minimizing the need for invasive testing of fetal chromosomal aneuploidies. Here, we report the initial clinical performance of NIPT in Korean pregnant women. Materials and Methods: MPS-based NIPT was performed on 910 cases; 5 mL blood samples were collected and sequenced in the Shenzhen BGI Genomic Laboratory to identify aneuploidies. The risk of fetal aneuploidy was determined by L-score and t-score, and classified as high or low. The NIPT results were validated by karyotyping for the high-risk cases and neonatal follow-up for low-risk cases. Results: NIPT was mainly requested for two clinical indications: abnormal biochemical serum-screening result (54.3%) and advanced maternal age (31.4%). Among 494 cases with abnormal biochemical serum-screening results, NIPT detected only 9 (1.8%) high-risk cases. Sixteen cases (1.8%) of 910 had a high risk for aneuploidy: 8 for trisomy 21, 2 for trisomy 18, 1 for trisomy 13, and 5 for sex chromosome abnormalities. Amniocentesis was performed for 7 of these cases (43.8%). In the karyotyping and neonatal data, no false positive or negative results were observed in our study. Conclusion: MPS-based NIPT detects fetal chromosomal aneuploidies with high accuracy. Introduction of NIPT as into clinical settings could prevent about 98% of unnecessary invasive diagnostic procedures.