• 제목/요약/키워드: non-working time

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허혈성 전조건화 유발이 심근보호에 미치는 영향에 관한 실험적 연구 (The Experimental Study for Myocardial Preservation Effect of Ischemic Preconditioning)

  • 이종국;박일환;이상헌
    • Journal of Chest Surgery
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    • 제37권2호
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    • pp.119-130
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    • 2004
  • 개심술 후 나타나는 심기능 저하는 수술 중 허혈로 인하여 생긴 심근손상에 의한 것으로 심근 허혈 상태가 반복되는 경우에 허혈 상태에 의한 심근기능의 손상이 축적되지 않고 오히려 먼저 온허혈 상태에 의하여 심근세포가 일종의 조건화 상태가 되어 허혈에 견디는 힘이 증가하여 장시간의 허혈이 오는 경우에 허혈에 의한 심근손상을 줄일 수 있다고 하여 이를 허혈성 전조건화라고 하는데, 허혈성 전조건화의 효과는 심근손상을 감소시키고, 재관류 시 심근회복에 좋은 영향을 미치며, 부정맥의 빈도를 감소시킨다고 하였다. 이러한 허혈성 전조건화를 본원에서 사용하는 중외1호 심정지액을 흰쥐의 적출 심장에 이용하여 심근보호 효과를 알아보고자 본 연구를 실시하였다. 대상 및 방법: 실험동물은 Sprague-Dawley계 수컷 흰쥐를 사용하였으며, 케뉼라를 삽관한 후 modified isolated working heart model에 부착 고정하였다. 관류과정은 비작업성 순환과 작업성 관류로 나누어 실시하였으며, 작업성 관류를 20분간 실시하고 이 때 심박동수, 대동맥압, 대동맥관류량, 관관류량을 측정기록 하였다. 대조군은 적출심장을 작업성 순환 20분 후 대동맥 차단과 동시에 심정지액을 주입하여 60분간 보존 후 재관류를 실시하여 회복시킨 군이며, 비교군은 허혈성 전조건화로 관류액 자체를 저산소증으로 만들어 허혈을 유발시킨 후 심정지액을 주입하여 60분간 보존시킨 군(제I군), 작업성 관류 20분 후 대동맥 차단을 실시하여 허혈을 유발시킨 후 재관류 없이 심근보호액을 45초(제II-1), 1분(제II-2군), 3분(제II-3군) 주입한 군과, 작업성 관류 20분 후 45초(제III-1군), 1분(제III-2군) 및 3분(제III-3군)간 대동맥 차단을 실시한 후 2분간 재관류를 실시하여 심장을 회복시킨 후 다시 동일 방법으로 2회 실시 후 심근보호액을 주입한 군으로 나누었으며, 모든 군에서 60분간 보존시킨 후 재관류를 실시하여 회복정도를 혈역학적 성적만을 측정 비교하였다. 결과: 자연 심박동 출현시간은 대조군에 비해 제I군, 제II-3군, 제III-2군 및 제III-3군에서 매우 늦은 출현시간을 보였고(p<0.01), 제II-1군과 제III-1군에서도 늦은 출현은 보였지만 통계적 유의성은 없었다(p=NS). 심박동수의 비교에서는 대조군에 비해 제III-1군이 가장 좋은 회복을 보였고(p<0.05), 비교군 간의 비교에서도 제III-1군이 제II-1군보다 좋은 회복을 보였다(p<0.05). 대동맥 수축기압에서도 제III-1군(p<0.05)에서 좋은 회복을 보였고, 대동맥 차단 군간에서도 제III-1군이 제II-1군에 비해 가장 좋은 회복을 보였다(1<0.01). 심박출량에서는 대조군에 비해 제III-1군이 좋은 회복률을 보였고(p<0.05), 비교군 간에서는 제III-1군이 제II-1군보다 좋은 회복을 보였으나 통계적 유의성은 없었지만(p=NS), 제III-2군이 제II-2군에 비해 좋은 회복을 보였다(p<0.05). 심부종의 평가에서는 대조군에 비해 제I군(p<0.01)과 제II-3군(p<0.05)에서 심부종이 심한 것을 알 수 있었다. 결론: 적출 심장만으로는 다른 장기의 영향을 배제한 경우에 심근보호액 자체보다 허혈 전조건화를 부여한 심근보호액 군에서 허혈 전조건화 시 심박동의 이상 징후가 출현하기 직전까지 짧은 시간 동안 허혈을 실시한 후 재관류시킨 뒤 심정지액을 주입하여 심장을 보호하는 것이 심기능 회복에 효과가 있는 것으로 생각되며, 앞으로도 계속적인 연구가 필요할 것이다.

하이브리드 인식 기술을 이용한 전사적 인적자원관리 (Enterprise Human Resource Management using Hybrid Recognition Technique)

  • 한정수;이정헌;김귀정
    • 디지털융복합연구
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    • 제10권10호
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    • pp.333-338
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    • 2012
  • 인적자원관리는 IT기술을 접목하여 다양한 변화를 가져오고 있다. 특히 HRM이 집단차원의 관리, 물리적 사업장, 근무시간의 제약, 개인적 접촉 등 비과학적 방법으로 이루어졌다면, 현재의 전자적 인적자원관리(e-HRM)는 개별 차원의 관리, 가상 작업 공간의 등장(예. 스마트워크센터, 홈워크 등), 근무시간의 유연화 및 탄력화, 컴퓨터 기반의 통계자료 및 과학적 방법에 의한 분석 및 관리를 근간으로 이루어지고 있다는 점에서 큰 차이가 있다. 따라서 환경의 변화에 따라 기업들은 보다 효율적이고 전략적인 인적자원 관리 체계를 구축하기 위하여 RFID 카드, 지문인식 근태관리 시스템 등 다양한 기술을 도입하고 있다. 본 논문에서는 효율적인 전사적 인적자원 관리를 위한 멀티 카메라를 이용하여 2D 및 3D 얼굴인식기술 기반의 근태관리, 출입통제관리 시스템을 개발하였다. 여기서는 기존 2D방식의 얼굴인식기술이 가지고 있는 문제점인 조명 및 자세에 따른 인식률 저하를 극복하여 90% 이상의 인식률을 확보하였다. 또한 3D 얼굴인식방식의 문제점인 많은 계산량을 개선하기 위하여 3D와 2D 인식기술을 병행하여 처리함으로써 하이브리드 영상인식 및 인식속도를 개선할 수 있었다.

단순 작업성 심관류 모델에서의 신생돈 심장의 보존 후 백혈구-제거 혈액을 이용한 재관류가 심근 VCAM-1 발현 및 심기능에 미치는 영향 (Effect of reperfusion with leukocyte-depleted blood on the expression of myocardial vascular cell adhesion molecule-1 (VCAM-1) and myocardial function in isolated working heart perfusion model)

  • 이정렬;석철준;서정욱;한재진
    • Journal of Chest Surgery
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    • 제33권3호
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    • pp.213-220
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    • 2000
  • Background: Adhesion of leukocytes to myocardium or vascular endothelium has been known as an importation initial step in the ischemia-reperfusion injury which may affect the cardiac function. Therefore, leukocyte-depleted reperfusion may inhibit ischemia-reperfusion induced functional and ultrastructural deterioration. In this study, we quantified the time-dependent expression of the vascular cell adhesion molecule-1(VCMA-1) on piglet myocardium and demonstrated its relation to functional recovery using isolated piglet heart perfusion model. Material and Method: Neonatal(1 to 3 day old) piglet heart was harvested with 4$^{\circ}C$ University of Wisconsin solution (UWS) and presrved in the same solution for 12 hours. Ex vivo model of an isolated working neonatal piglet heart perfusion consisting of membrane oxygenator and roller-pump was used (Fig. 1). Hearts were grouped into leukocyte-non-depleted (group A, n=8) and leukocyte-depleted group(group B, n=8). In group B, hearts were reperfused with leukocyte-depleted blood using a leukocyte filter (Sepacell R, Asahi Medical, Japan). Segments of right atrium were taken before and after 1, 2, 3, and 4 hours of reperfusion for the evaluation of expression of VCAM-1. The intensity of immunohistochyemical satining of the VCAM-1 on the myocardium were graded semiquantitatively (0 to 4). For the evaluation of myocardial stroke work indices were calculated as well at the same time-points. Result: Mean expressins of VCAM-1 on the myocardium at 0, 1, 2, 3, adn 4 hours of reperfusion were 0.63, 1.44, 1.64, 2.65, and 3.34 in group A, while 0.56, 1.40, 1.50, 1.88 and 2.14 in group B (Fig. 3). Mean stroke work indices at 0.5, 1, 2, 3, and 4 hours after reperfusion were 1.35$\times$104, 1.32$\times$104, 1.14$\times$104, 0.81$\times$104, 0.68$\times$104 erg/gm in group A, while 1.40$\times$104, 1.43$\times$104, 1.43$\times$104, 1.28$\times$104, and 1.12$\times$104 erg/em in group B(Fig. 4). Conclusion : In this study, we demonstrated that leukocyte-depletion attenuated the expression of VCAM-1 during reperfusion and the time-dependent functional deterioration of the myocardium was well correlated with the degree of VCAM-1 expression.

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호스피스 자원봉사활동의 실태 및 지원에 관한 연구 - 대전ㆍ충청권을 중심으로

  • 황영숙;모선희
    • 호스피스학술지
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    • 제5권1호
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    • pp.14-25
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    • 2005
  • This study was conducted to examine the present state, types of services, difficulties, education programs, motivation, satisfaction and attitude of hospice volunteers and also to suggest supporting programs for the volunteer. For these purposes, a questionnaire was distributed among the 200 hospice volunteers in ten hospice organizations in Daejeon and Chungcheong province. In this research, 85.5% of the respondents were women and most of them were housewives in their forties and fifties. The majority of hospice volunteers had an education background of more than high school. Christianity (94%) was the dominant religion of volunteers. Among the service area of the hospice, emotional caring, such as listening closely and establishing empathy were the most frequently done by the respondents and the next one was spiritual care. Hospice volunteers who had started with altruistic motivation show more dynamic activities in emotional, spiritual, physical caring and so on, than those with non-altruistic motivation. Most of the respondents expressed that they felt a hospice volunteer was valuable. However they had a hard time to overcome the sorrow coming from sharing empathy with the dying patients. Those who had started with altruistic motivation usually took part in two times per a week and had more positive attitude. Volunteers who had been working more than five years showed better attitude than those who had been working less than three years. The longer the voluntary services, the more positive attitude experienced by volunteers. Hospice volunteers encountered the most considerable difficulty with lack of background knowledge and their actual capability. Insufficiency of time was the next reason for the considerable difficulty of the hospice volunteer. On the other hand, those who served more than twice per week replied that lack of background knowledge and their capability were the least considerable difficulty. Insufficiency of time was the reason of difficulty for male volunteers, as well as for females under thirty and those in their forties and fifties respectively. Generally most of the hospice volunteers (70%) were satisfied with their services and they usually satisfied with physical caring, spiritual caring, hospice's family caring. The less difficulty in voluntary services, more satisfaction for the volunteers in the end. There is a positive correlation between a attitude of the hospice volunteer and frequency of voluntary services while the volunteers' difficulty affect negatively their attitude as well as the frequency of voluntary services. Most of the hospice volunteers want to have more education about basic skills, volunteer's attitude and role, spirituality, the way of attending on the hospice and so on. Most of them considered discussion and sharing different cases as the most effective method. They also wish to had more supporting programs for the hospice volunteers(in the order of their needs) such as regular events, newsletters, personal concern, social meetings among the volunteers, insurance and minimum expenses. Based on the study results, more programs should be run in order to activate the voluntary services regardless of their gender and education background. A continuous practical supporting policy and education programs are required in order to provide special education and training courses considering every field of voluntary services. Expanding the role of the volunteers allows them more opportunities to take part in voluntary services and th activate participation. It is necessary to establish a new hospice system as a part public medical system, which can not only facilitate the voluntary services for a hospice but also enhance professional hospice volunteers. Finally, experts are needed to operate the voluntary services effectively.

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스마트워크 환경에서 지속사용의도에 대하여 IT기업과 비IT기업 간의 차이분석에 관한 연구 -한국 중소기업을 중심으로 (A Study on the Analysis of Difference between IT and Non-IT Companies on the Smart Work Environment Continuous Use Intention - Focusing on Korean Small and Medium Enterprises)

  • 정수용;신용태
    • 디지털융복합연구
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    • 제16권3호
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    • pp.249-259
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    • 2018
  • 본 연구는 중소기업에 근무하고 있는 직원들을 대상으로 현재 스마트워크가 지속사용의도에 미치는 영향에 대해 알아보고, 최종적으로 스마트워크 환경이 IT기업과 비IT기업 간의 차이를 알아보고자 하였다. 본 연구를 위해서 중소기업에 근무하고 있는 직원들로부터 설문자료를 수집하였다. 수집한 설문자료를 통해 실증분석을 하였으며, 신뢰도분석, 타당성분석, 판별타당성분석, 구조방정식 모델의 적합도 검정을 통해 최종적으로 연구모형을 검증하고 최종적으로 IT기업과 비IT기업의 차이분석을 실시하였다. 연구분석 결과는 직무특성의 직무효율성, 직무자율성 요인은 매개변수인 지각된 유용성과 직무만족에 긍정적인 영향을 미치는 것으로 나타났으며, 직무형태의 시간유연성은 매개변수인 지각된 유용성과 직무만족에 영향을 미치지 못하는 것으로 나타났고, 공간유연성은 직무만족에만 영향을 미치는 것으로 나타났다. 매개변수인 지각된 유용성은 직무만족, 지속사용의도에 긍정적인 영향을 미쳤고, 최종적으로 직무만족은 지속사용의도에 긍정적인 영향을 미쳤다. 그리고 IT기업과 비IT기업 간의 차이도 있는 것으로 나타났다. 본 연구 결과를 통해 스마트워크 환경을 통해 근무자, 조직에게 긍정적인 영향을 유도시킬 수 있으며, 근무자들에게 기존보다 기업의 특성에 맞게 더 나은 업무환경을 제공할 수 있다고 사료된다.

생애과정 전환기의 생활시간 배분에 관한 연구 -중.고령자의 생활시간 비교를 중심으로- (A Study on Time Allocation in Transition to Old Age -Focusing on the Patterns of Time Allocation among People aged 45 or more-)

  • 박미희;변금선
    • 한국사회복지학
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    • 제65권3호
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    • pp.29-52
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    • 2013
  • 본 연구는 2009년 통계청 생활시간조사자료를 이용하여 연령과 사회구조적 층화에 따른 시간 배분 경향을 분석하였다. 중고령자의 생활시간배분 경향을 총체적으로 파악하기 위해 유급노동과 더불어 가사활동, 사회참여, 여가시간을 포괄적으로 분석하였으며, 생활시간 배분경향이 연령과 사회구조적 층화의 상호작용에 따라 달라지는지 확인하기 위해 토빗회귀분석을 실시하였다. 분석결과, 중고령자의 시간배분 경향은 유급노동시간의 점진적 감소와 가사노동 및 수동적 여가의 증대로 나타났다. 그러나 이러한 경향은 사회구조적 층화에 따라 상이하게 분화되고 있었다. 교육수준이 높을수록, 무배우자가 유배우자에 비해, 연령증가에 따른 유급노동시간의 감소가 급격히 나타나고 여가시간은 가파르게 증가하는 경향을 보였다. 농가는 비농가에 비해 연령에 따른 노동시간 감소가 완만하게 나타났으며, 여성은 남성에 비해 연령증가에 따라 가사와 돌봄활동을 감소시켰지만, 생산활동시간 총량은 크게 변하지 않았다. 이상의 분석결과를 바탕으로 본 연구에서는 효과적인 고령화 정책을 마련하기 위해 고령자를 단일집단으로 간주하는 획일적인 접근을 탈피하고, 고령화라는 변화를 겪는 이들이 놓여있는 다양한 사회구조적 요인을 반영할 필요성이 있음을 제언하였다.

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Use of Dye Deposition in Cows' Excised Genital Tract to Evaluate Inseminators' and Refreshment Training to Refreshment Training to Improve Their Skill

  • Mohammed S.;Mohammad S. H.;Mohhammad A. R. S.;Khan A.H.M.S.I.
    • 한국수정란이식학회지
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    • 제20권2호
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    • pp.157-162
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    • 2005
  • To find out the possible inefficiencies of artificial inseminators at rectovaginal insemination in cows, inseminators' skill were evaluated by controlling the semen thawing procedure adopted and by using the technique of dye deposition in the genital tract of slaughtered cows. This was followed by refreshment training for the inseminators. Thirty seven artificial insemination technicians regularly working in the government, cooperative and NGO (Non Government Organization) artificial insemination programmes at different places of Bangladesh were included in the study. Individual technicians were asked to thaw a semen straw and deposit dye in the genital tract of slaughtered cows following the procedures they would have adopted in their actual practices of insemination. The time and water temperature adopted by technicians were recorded and genital tract after sham artificial insemination was dissected to determine the site of dye deposition. Then, the inseminators took part in a three days intensive training program. The training program was ended up with the same tests for thawing frozen semen straw and dye deposition in the genital tract of slaughtered cows. At pre training evaluation, only $25\%\;and\;72\%\;(n=36)$ inseminators adopted co..ect thawing time and temperature, respectively. At post training evaluation, all inseminators thawed semen straws for proper time and temperature. At pretraining evaluation, $21(57\%),\;11 (30\%)\;and\;3(8\%)$ inseminators deposited dye at the body of uterus, in the vagina or in cervix, and into the horn of uterus, respectively. In $2(5\%)$ cases dye did not pass into the genital tract, instead back flowed through the space between the barrel of insemination gun and sheath. At post training evaluation, all inseminators successfully deposited dye in the body of uterus. Frequent evaluation of inseminators' skill and subsequent training would help improvement of the artificial insemination technicians' skill.

점탄성유체의 저항 및 열전달 감소현상과 퇴화의 영향에 관한 연구 (A Study on the Drag and Heat Transfer Reduction Phenomena and Degradation Effects of the Viscoelastic Fluids)

  • 엄정섭;전찬열;유상신
    • 설비공학논문집
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    • 제2권1호
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    • pp.37-48
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    • 1990
  • The drag and heat transfer reduction phenomena and degradation effects of drag reducing polymer solutions which are known as the viscoelastic fluids are investigated experimentally for the turbulent circular tube flows. Two stainless steel tubes are used for the experimental flow loops. Aqueous solutions of Polyacrylamide Separan AP-273 with concentrations from 300 to 1000 wppm are used as working fluids. Flow loops are set up to measure the friction factors and heat transfer coefficients of test tubes in the once-through system and the recirculating flow system. Test tubes are heated by power supply directly to apply constant heat flux boundary conditions on the wall. Capillary tube viscometer and falling ball viscometer are used to measure the viscous characteristics of fluids and the characteristic relaxation time of a fluid is determined by the Powell-Eyring model. The order of magnidude of the thermal entrance length of a drag reducing polymer solution is close to the order of magnitude of the laminar entrance length of Newtonian fluids. Dimensionless heat transfer coefficients of the viscoelastic non-Newtonian fluids may be represented as a function of flow behavior index n and newly defined viscoelastic Graetz number. As degradation continues viscosity and the characteristic relaxation time of the testing fluids decrease and heat transfer coefficients increase. The characteristic relaxation time is used to define the Weissenberg number and variations of friction factors and heat transfer coefficients due to degradation are presented in terms of the Weissenberg number.

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Control Variables of Remote Joint Analysis Realization on the M2M Case

  • Lim, Sung-Ryel;Choi, Bo-Yun;Lee, Hong-Chul
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제6권1호
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    • pp.98-115
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    • 2012
  • New trend called ubiquitous leads the recent business by standardization and integration. It should be the main issue how to guarantee the integration and accountability on each business, especially in mission critical system which is mainly supported by M2M (Machine to Machine) control mechanism. This study is from the analysis of digital forensics case study that is from the M2M Sensing Control Mechanism problem of the "Imjin River" case in 2009, where a group of family is swept away to death by water due to M2M control error. The ubiquitous surroundings bring the changes in the field of criminal investigation to real time controls such as M2M systems. The needs of digital forensics on M2M control are increasing on every crime scene but we suffer from the lack of control metrics to get this done efficiently. The court asks for more accurately analyzed results accounting high quality product development design. Investigators in the crime scene need real-time analysis against the crime caused by poor quality of mission critical systems. It seems to be every need of Real-Time-Enterprise, so called ubiquitous society on the case. We try to find the efficiency and productivity in discovering non-functional design defects in M2M convergence products focusing on three metrics in study model with quick implementation. Digital forensics system in present status depends on know-how of each investigator and is hard to expect professional analysis on every field. This study set up a hypothesis "Co-working of professional investigators on each field will qualify Performance and Integrity" especially in mission critical system such as M2M and suggests "Online co-work analysis model" to efficiently detect and prevent mission critical errors in advance. At the conclusion, this study proved the statistical research that was surveyed by digital forensics specialists around M2M crime scene cases with quick implementation of dash board.

Electro-Optical Characteristics of the Ion-Beam-Aligned FFS-LCD on a Diamond-like-Carbon Thin Film

  • Hwang, J.Y.;Park, C.J.;Seo, D.S.;Jeong, Y.H.;Kim, K.C.;Ahn, H.J.;Baik, H.K.
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2004년도 Asia Display / IMID 04
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    • pp.1132-1136
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    • 2004
  • In this paper, we intend to make FFS mode cell with LC alignment used non-rubbing method, ion beam alignment method on the a-C:H thin film, to analyze electro-optical characteristics in this cell. We studied on the suitable inorganic thin film for FFS-LCD and the aligning capabilities of nematic liquid crystal (NLC) using the new alignment material of a-C:H thin film as working gas at rf bias condition. A high pretilt angle of about 5$^{\circ}$ by ion beam(IB) exposure on the a-C:H thin film surface was measured. An excellent voltage-transmittance (V-T) and response time curve of the ion-beam-aligned FFS-LCD was observed with oblique ion beam exposure on the DLC thin films.

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