• Title/Summary/Keyword: non-randomized controlled trial

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Effect of Visiting and a Smartphone Application Based Infection Prevention Education Program for Child Care Teachers: A Non-Randomized Controlled Trial (보육교사 대상 방문 및 스마트폰 앱 기반 감염예방교육 프로그램 효과: 비무작위 대조군설계)

  • Yang, Yun Jeong;Kwon, In Soo
    • Journal of Korean Academy of Nursing
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    • v.47 no.6
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    • pp.744-755
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    • 2017
  • Purpose: This study was performed to develop an infection prevention education program for child care teachers and to verify its effects. Methods: The study was conducted using a nonequivalent control group with a pretest-posttest design. Four private daycare centers (2 centers per city) that were alike in terms of the number of children by age, number of child care teachers, and child care environment were chosen. Participants were assigned to the experimental group (n=20) or control group (n=20). As a part of the program, visiting education (90 min) was provided in the 1st week, and smartphone application education (10 min) was provided thrice a week, in the 2nd and 3rd weeks. Results: Child care teachers' self-efficacy for infection prevention revealed a significant interaction effect between the group and time of measurement (F=21.62, p<.001). In terms of infection prevention behavior, a significant difference was observed between the experimental and control groups (z=-5.36, p<.001). Conclusion: The program implemented in this study was effective in improving the infection prevention self-efficacy and infection prevention behavior of child care teachers. Thus, this program may be effective in enhancing their infection control.

Survival rates against fracture of endodontically treated posterior teeth restored with full-coverage crowns or resin composite restorations: a systematic review

  • Suksaphar, Warattama;Banomyong, Danuchit;Jirathanyanatt, Titalee;Ngoenwiwatkul, Yaowaluk
    • Restorative Dentistry and Endodontics
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    • v.42 no.3
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    • pp.157-167
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    • 2017
  • This systematic review aims to summarize the current clinical studies that investigated survival rates against fracture of endodontically treated posterior teeth restored with crowns or resin composite restorations. Literature search were performed using keywords. Publications from 1980 to 2016 were searched in PubMed, ScienceDirect, ISI Web of SCIENCE, MEDLINE, and SCOPUS. Included studies were selected based on inclusion and exclusion criteria. Three clinical studies were included: 1 randomized controlled trial and 1 prospective and 1 retrospective cohort studies. Pooled survival rates ranged from 94%-100% and 91.9%-100% for crowns and resin composite, respectively. The majority of teeth had no more than 3 surface loss of tooth structure. The studies included were heterogeneous, and were not appropriate for further meta-analysis. Current evidence suggested that the survival rates against the fracture of endodontically treated posterior teeth restored with crowns or resin composites were not significantly different in the teeth with minimum to moderate loss of tooth structure.

The Effect of Laughter Therapy on Anxiety, Depression and Stress of Cancer Patients Admitted to Long-Term Care Unit

  • Kim, Seongeun;Kim, Miseon;Jeong, Hyeoncheol
    • Physical Therapy Rehabilitation Science
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    • v.10 no.2
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    • pp.197-204
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    • 2021
  • Objective: This study is based on a parallax design before and after a non-equivalent control group to examine the effects of laughter therapy on the anxiety, depression, and stress in patients with cancer admitted to a nursing hospital. Design: A randomized controlled trial. Methods: Data collection was conducted on 34 patients who agreed to participate in the study among patients admitted to E Cancer Hospital from September to November 2018. Laughter treatment interventions were performed three times a week for 50 minutes each and a total of eight times. In this study, a tool developed by Spielberger was used to measure state anxiety, a tool developed by Beck was used to measure depression, and the Perceived Stress Scaled eveloped by Cohen was used to measure stress. Results: Anxiety was significantly lower in the experimental group than in the control group (F=10.74, p=0.003). Depression was lower in both the experimental group and the control group that did not participate in the laughter therapy intervention and was not significant (F=0.58, p=0.451). Stress was significantly lower in the experimental group than in the control group (F=4.36, p=0.045). Conclusions: The results of this study suggest that laughter therapy has a positive effect on reducing anxiety and stress in patients with cancer admitted to nursing hospitals.

Non-inferiority study of the efficacy of two hyaluronic acid products in post-extraction sockets of impacted third molars

  • Yang, Hyunwoo;Kim, Junghun;Kim, Jihong;Kim, Dongwook;Kim, Hyung Jun
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.42
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    • pp.40.1-40.5
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    • 2020
  • Background: Hyaluronic acid (HA) is well known to exert an anti-inflammatory effect during oral wound healing and is commonly applied after tooth extraction. However, no double-blind randomized controlled study comparing two hyaluronate mouthwash products has been conducted so far. The aim of this study was to comparatively analyze the efficacy of Mucobarrier® and Aloclair® in terms of clinical symptoms. Results: A total of 112 patients were randomly assigned to assess the degree of discomfort, pain reduction, redness, burning sensation, and swelling between two groups on the day of surgery and 7 days later in a double blind test, with a total 56 Aloclair patients and 56 Mucobarrier patients. There was no statistically significant difference in the overall discomfort, degree of pain reduction, redness, burning sensation, and swelling between the Mucobarrier and Aloclair groups. Conclusion: The local application of hyaluronic acid mouth wash after wisdom tooth extraction is beneficial in reducing overall discomfort and pain reduction, and the clinical utility of Mucobarrier® is no different from Aloclair®. Trial registration: Institutional Review Board of Yonsei University College of Dentistry, 2-2018-0036. Registered 10 September 2018-prospectively registered, https://eirb.yuhs.ac/

The Effect of Side-Step Tasks Based Circular Training Program on Balance and Gait in Stroke Patients

  • Sang Jun Son;Joong-Hwi Kim
    • Physical Therapy Rehabilitation Science
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    • v.11 no.4
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    • pp.384-390
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    • 2022
  • Objective: The purpose of this study was to investigate the effect of the side-step tasks based circular training program (STCT) on balance and gait characteristics in stroke patients. Design: A randomized controlled trial Methods: Twenty-four stroke patients were randomly divided into two groups of twelve patients each. One group was applied with the STCT whereas the other group was treated with conservative physiotherapy (CP). The ability of gait was measured in 10m walking test and stride length on both side using BTS G-WALK (BTS Bioengineering S.p.A, Italy) and the ability of balance was measured in Berg Balance Scale (BBS) and Timed Up and Go Test (TUG). Results: The STCT group was significant differences in the balance parameters of BBS and TUG (p<0.05) and showed significant differences in gait variables in 10m walking speed, stride length of affected and non-affected side after the experiment before and after the experiment (p<0.05). In addition, the STCT group showed a significant difference in BBS compared to the control group (p<0.05). Conclusions: The results of this study confirmed that the side-step tasks based circular training program (STCT) improves balance and walking ability in stroke patients. STCT is expected to be used as a useful intervention method for stroke rehabilitation.

Effect of Thoracic Joint Mobilization and Breathing Exercise on The Thickness of The Diaphragm, Expansion of The Chest, Respiratory Function, and Endurance in Chronic Stroke Patients

  • Hyunmin Moon;Jang-hoon Shin;Wan-hee Lee
    • Physical Therapy Rehabilitation Science
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    • v.12 no.3
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    • pp.278-292
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    • 2023
  • Objective: This study was performed to investigate the effects of thoracic joint mobilization and breathing exercises on diaphragmatic thickness, chest expansion, respiratory function, and endurance in patients with chronic stroke. Design: Randomized controlled trial Methods: The study included 24 chronic stroke patients who were randomly divided into two groups. The experimental group (12 people) performed 15 minutes of thoracic joint mobility exercises and 15 minutes of breathing exercises, three times a week for 6 weeks, 30 minutes each time. The control group (12 people) received 15 minutes of conservative physical therapy and 15 minutes of breathing exercises, 3 times a week for 6 weeks, 30 minutes per session, the same as the experimental group. The experimental and control groups performed the same breathing exercises. To assess training effectiveness, changes in diaphragm thickness, chest expansion, respiratory function, and endurance were measured. Results: As a result, the experimental group exhibited significant improvements in diaphragm thickness, chest expansion, and respiratory function. The endurance mode also displayed significant enhancement (p<0.05), a finding consistent with the control group. However, the experimental group displayed more substantial improvements in non-affected diaphragm thickness and thoracic expansion compared to the control group (p<0.05). Conclusions: Drawing from these findings, breathing exercise which combine thoracic mobilization, will be actively utilized in addition to physical therapy interventions in clinical trials as an effective intervention method.

Comparison of Heparin Solution and 0.9% Normal Saline Solution Flushing to Secure the Patency of Non-Tunneled Central Venous Catheters (비턴넬형 중심정맥관 개방성 유지를 위한 헤파린 희석액 관류와 생리식염수 관류의 비교)

  • Kim, Ji Hye;Seo, Eun Ji;Park, Hee Jung;Kim, Si Hyeon;Min, Ja;Park, Jeong Yun;Kim, Song Cheol
    • Journal of Korean Clinical Nursing Research
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    • v.20 no.3
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    • pp.326-336
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    • 2014
  • Purpose: The purpose of this study was to compare the effectiveness of heparin and 0.9% normal saline solution flushing for maintaining patency of non­tunneled central venous catheters in patients with surgery. Methods: A randomized controlled clinical trial was performed. Fifty­eight patients were prospectively enrolled and fifty-four patients were completed the study. The heparin group consisted of 30 patients given 100u/ml diluted heparin flushing and the normal saline group consisted of 24 patients with 0.9% sodium chloride flushing. Results: There was no significantly difference in occlusion between the heparin group and the normal saline group in non­tunneled central venous catheters' occlusion. Also there was no difference between these two groups in catheter­related infections. Conclusion: Flushing with 0.9% normal saline is as effective as flushing with heparin solution in maintaining the patency of non­tunneled central venous catheters. In this study, however, the duration of central line use was short and the infection occurrence was little. Further studies are warranted with a larger sample size at multiple centers.

Effects of Applying a Vibration Stimulation to Paretic Side and Non-Paretic Side on Balance and Gait in Stroke Patients: a Pilot Study

  • Jeong, Ho Jin;Park, Sung Hwan;Jeon, Jong Yun;Kim, Byeong Geun
    • The Journal of Korean Physical Therapy
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    • v.34 no.5
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    • pp.193-197
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    • 2022
  • Purpose: The purpose of this pilot study was to assess the feasibility of a proposed study "To investigate the effects of applying a vibration stimulation to the paretic and non-paretic sides on balance and gait in stroke patients" before proceeding with the main study. Methods: A total of 30 patients who had suffered a stroke and who met the selection criteria participated in this study. However, only 14 patients completed the study. The study subjects were randomly assigned to vibration stimulation on either both sides (B group) or the paralyzed side (P group). The interventions were applied for six weeks. The patients were assessed using the Berg balance scale (BBS), Timed up and go (TUG), 10-meter walk (10 MW), and 6-minute walk (6 MW) tests. Results: There was a significant difference before and after the application of vibration stimulation in the BBS, TUG, 10MW, and 6 MW tests in the B group (p<0.05). Similarly, there was also a significant difference observed in the 10 MW and 6 MW tests in the P group (p<0.05). The difference between the two groups was not significant in the BBS, TUG, 10 MW, and 6 MW tests (p>0.05). Conclusion: This pilot study suggests that it would be feasible to conduct a large-scale randomized controlled trial (RCT) to examine the effects of applying a vibration stimulation to the paretic and non-paretic sides, on the balance and gait in stroke patients.

Review of Acupuncture Treatment for Hypertension in Clinical Trials (임상연구의 고혈압 침치료법에 대한 고찰)

  • Jung, So-Young;Park, Ji-Eun;Kim, Jung-Eun;Kim, Ae-Ran;Choi, Sun-Mi
    • The Journal of Korean Medicine
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    • v.33 no.1
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    • pp.12-23
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    • 2012
  • Objectives: This study evaluated clinical trials of acupuncture treatment for hypertension and to assess their methodology and results. Methods: Eight Korean databases and four international databases were searched for clinical trials of acupuncture treatment for hypertension up to June 2011. Study quality was assessed using the risk of bias (ROB) tool. Results: Twenty-four trials of acupuncture for hypertension were included. There were 14 randomized and 1 non-randomized controlled trials and 9 before-after studies. The most frequently used acupuncture points were zsnli (ST36), qch (LI11), fngch (GB20), snynjio (SP06), snjin (LI03) and hgu (LI04). In more than half of the studies, needle retention time was 20~30 minutes. Compared to baseline, change of blood pressure after treatment was significant in all studies. However, the results of effect on blood pressure between acupuncture and control were not consistent. Conclusions: There is insufficient evidence to suggest that acupuncture is an effective treatment for hypertension. Further well-designed clinical trials will be required to evaluate the effects and safety of acupuncture treatment for hypertension.

The effect of treadmill gait training with patellar taping on gait abilities in chronic stroke patients

  • Shin, Jin;Chung, Yijung
    • Physical Therapy Rehabilitation Science
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    • v.4 no.2
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    • pp.94-102
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    • 2015
  • Objective: The purpose of this study is to investigate the effect of treadmill gait training with patellar taping on gait abilities in chronic stroke patients. Design: Randomized controlled trial. Methods: Thirty chronic stroke patients who have been diagnosed at least six months or before were recruited in Gyeongin Rehabilitation Center Hospital, located in Incheon. Patients who were enrolled in this study were randomized to experimental group (n=15) or control group (n=15). Treadmill with patella taping training group patients were applied with patellar taping when they were being trained on a treadmill. Control group patients were being trained on a treadmill without any kind of taping. Gait parameters were measured with a GAITRite$^{(R)}$ system which evaluated gait performances. Gait trainings were done for 30 min/day, 5 days/week, for 4 weeks. Results: After treadmill training, treadmill with patella taping training group showed a significant improvement in gait abilities, including velocity, cadence, paretic and non-paretic step length, and double support period (p<0.05). However, in general treadmill group, there were no significant differences in gait parameters except velocity and cadence. There was a significant difference in gait performance in the experimental group compared with the control group, except for the gait symmetry ratio (p<0.05). Conclusions: According to this result of this study, it seems that application of patellar taping in treadmill gait training for chronic stroke patients significantly improved gait abilities of these patients. Also, we can conclude that patella taping is thought to be useful in real clinical settings where there are many chronic patients who are in need of improvement in their gait abilities.