• 한국물환경학회지
• /
• 제23권6호
• /
• pp.951-960
• /
• 2007

Window interface to Hydrological Simulation Program-FORTRAN (WinHSPF) developed by the United States Environmental Protection Agency (EPA) was applied to the upstream of Nam-Han river watershed to examine its applicability for loading estimates in watershed scale and to evaluate non-point source control scenarios using BMPRAC in WinHSPF. The WinHSPF model was calibrated and verified for water flow using Ministry of Construction and Transportation (MOCT, 3 stations, 2003~2005) and water qualities using Ministry of Environment (MOE, 5 station, 2000~2006). Water flow and water quality simulation results were also satisfactory over the total simulation period. But outliers were occurred in the time series data of TN and TP at some regions and periods. Therefore, it required more profit calibration process for more various parameters. As a result, all the study was performed within the expectation considering the complexity of the watershed, pollutant sources and land uses intermixed in the watershed. The estimated pollutant load for annual average about $BOD_5$, T-N and T-P respectively. Nonpoint source loading had a great portion of total pollutant loading, about 86.5~95.2%. In WinHSPF, BMPRAC was applied to evaluate non-point source control scenarios (constructed wetland, wet detention ponds and infiltration basins). All the scenarios showed efficiency of non-point source removal. Overall, the HSPF model is adequate for simulating watersheds characteristics, and its application is recommended for watershed management and evaluation of best management practices.

• 한국포장학회지
• /
• 제27권3호
• /
• pp.141-147
• /
• 2021

The foreign trends of noncompliance occurring frequently in food contact materials during the period of 2011-2019 was investigated by analyzing the food safety risk information DB in the National Food Safety Information Service (NFSI). A total of 2,042 cases of noncompliance of food utensils, containers, and packages were classified into 5 violation categories; administrative procedures, manufacturing and processing standards, residues and migration standards, labeling and advertising, and quality standards. This was again subcategorized according to non-compliance causative factors. The non-compliances in residues and migration standards comprised the largest proportion (76.4%) of the violative categories. The number of noncompliance information collected in 2011 was 88 cases and increased to 373 cases in 2019. A 72.8% of the non-compliance case was identified to be products of 4 countries (China 64.2%, Germany 4.0%, Japan 3.2%, and Taiwan 3.1%), those produce large quantities of containers and packaging products. During the period of 2011-2019, the number of illegal use of hazardous materials and illegal recycling of waste synthetic resins has decreased to less than one a year since 2014. On the other hand, after 2016, inconsistency of heat-resisting temperature labeling (Taiwan), non-compliance in paper container's strength standards, violation of printing standards, and the risk of consumer injury while using the products were newly reported due to the strengthening of consumer safety protection regulations. Migration of hazardous substances in synthetic polymer products such as heavy metals, melamine and formaldehyde in melamine tableware, primary aromatic amines which are colorant components in kitchenware such as ladles and spatulas, and phthalate plasticizers have been continuously reported with high frequency.

• Journal of Ginseng Research
• /
• 제46권1호
• /
• pp.104-114
• /
• 2022

Background: Abnormalities of myelin, which increases the efficiency of action potential conduction, are found in neurological disorders. Korean Red Ginseng (KRG) demonstrates therapeutic efficacy against some of these conditions, however effects on oligodendrocyte (OL)s are not well known. Here, we examined the effects of KRG-derived components on development and protection of OL-lineage cells. Methods: Primary OL precursor cell (OPC) cultures were prepared from neonatal mouse cortex. The protective efficacies of the KRG components were examined against inhibitors of mitochondrial respiratory chain activity. For in vivo function of Rb1 on myelination, after 10 days of oral gavage into adult male mice, forebrains were collected. OPC proliferation were assessed by BrdU incorporation, and differentiation and myelination were examined by qPCR, western blot and immunocytochemistry. Results: The non-saponin promoted OPC proliferation, while the saponin promoted differentiation. Both processes were mediated by AKT and extracellular regulated kinase (ERK) signaling. KRG extract, the saponin and non-saponin protected OPCs against oxidative stress, and both KRG extract and the saponin significantly increased the expression of the antioxidant enzyme. Among 11 major ginsenosides tested, Rb1 significantly increased OL membrane size in vitro. Moreover, Rb1 significantly increased myelin formation in adult mouse brain. Conclusion: All KRG components prevented OPC deaths under oxidative stress. While non-saponin promoted proliferation, saponin fraction increased differentiation and OL membrane size. Furthermore, among all the tested ginsenosides, Rb1 showed the biggest increase in the membrane size and significantly enhanced myelination in vivo. These results imply therapeutic potentials of KRG and Rb1 for myelin-related disorders.

• 법제연구
• /
• 제53호
• /
• pp.177-211
• /
• 2017

빅데이터(Big Data), 사물인터넷(Internet of Things), 인공지능(Artificial Intelligence)과 같은 새로운 ICT 기술과 서비스가 등장하고 발전해가는 과정에서 이와 같은 새로운 혁신이 가져올 미래의 변화상을 4차 산업혁명(Fourth Industrial Revolution)이라고 부르고 있다. 이러한 4차 산업혁명이발전하여 변화하게 될 우리의 미래는 데이터 기반 사회 혹은 경제라고할 수 있고, 그 중심에 개인정보가 있기 때문에 개인정보보호법제를 어떻게 정비할 것인가에 따라서 개인정보의 보호라는 측면과 개인정보의 활용을 통한 경제의 발전에 서로 다른 영향을 줄 수 있다. 4차 산업혁명을주도하고자 하는 우리나라의 입장에서 개인정보의 활용도 포기할 수 없는 법익임과 동시에 개인정보로부터 보호하고자 하는 개인의 법익 또한포기할 수 없는 중요한 법익이다. 따라서 양자를 조화시키기 위하여 합리적인 방향으로의 개인정보보호법제의 전환이 필요하다. 이러한 관점에서이 글에서는 개인정보보호법제의 중복과 부조화라는 문제, 개인정보보호법의 적용범위 및 판단기준의 불명확, 합리적 개인정보 활용 수요에 대한유연성 부족, 동의기반의 형식적 규제 중심의 법제, 개인정보의 국가간이동에 대한 규제 사각지대와 역차별이라는 문제점을 지적하였다. 이러한문제점들을 해결하고 4차 산업혁명 시대에 적합한 개인정보보호법제를만들기 위한 개선방향으로서 개인정보보호법제의 목적과 규제방향을 개선하여 개인정보보호와 안전한 활용의 양 측면을 모두 고려할 것을 제안하였고, 개인정보보호법제의 체계 정비 및 법령 사이의 균형과 조화도 중요한 방향으로 설정하였다. 지속적인 논란이 되는 개인정보 정의 규정에대하여도 합리적 판단 기준의 설정과 그것을 명확화하기 위한 입법론적인 검토가 필요함을 지적하고, 개인정보 활용 영역의 확대 방안으로서 중간 영역으로서의 익명화 정보를 허용하는 방안에 대하여도 검토가 필요함을 지적하였다. 또한 개인정보의 합법적이고 비침해적인 이용을 위한입법론적 검토와 함께 개인정보 수집 동의 제도를 개선하여 대상별 차등화하는 방안과 함께 개인정보의 국가간 이동에 대한 규제 실효성을 확보하기 위한 법제개선의 필요성도 제안하였다. 이 글에서 논의한 사항 외에도 여러 과제가 존재할 수 있지만, 전반적으로 위에서 지적한 방향성을유지하면서 개인정보의 보호와 활용이 조화가 되어 안전한 개인정보의활용체계가 구축될 수 있는 방향으로 법제의 개선을 이뤄가야 할 것이다.

• 한국한의학연구원논문집
• /
• 제11권2호
• /
• pp.67-96
• /
• 2005

This Study focused on IPC (International Patent Classification) for TKM (Traditional Korea Medicine) Paper. The results processed for 9,000 TKM paper by using 8th in IPC Classification. The name of Herbal Medicine assigned to IPC Classification, we assigned to two part for main-Classification(A61K) and sub-Classification (A61P). The results obtained about 77% for A61K and about 96% for A61K36 among them. And also analysed about 23% for sub-Classification(A61P) additionally. Main-Classification is distributed A61K > A61H37 > A61B5 > A61N > A61M1. Detailed Main-Classification for A61K is distributed A61K36 > A61K35 > A61K33 among Main-Classification. TKM Paper mainly analysed A61K36 and A61H37 in Main-Classification. According to the results. 'The Korean Journal of Herbology' has high-valued for Utilization as a Non Patent Document. we should constructed Database system for protection of intellectual property rights. And after We will registered minimum documentation of PCT.

• 한국정보보호학회:학술대회논문집
• /
• 한국정보보호학회 2006년도 하계학술대회
• /
• pp.123-132
• /
• 2006

Biometric-based authentication can provide strong security guarantee about the identity of users. However, security of biometric data is particularly important as the compromise of the data will be permanent. To protect the biometric data, we need to store it in a non-invertible transformed version. Thus, even if the transformed version is compromised, the actual biometric data remains safe. In this paper, we propose an approach to protect finger-print templates by using the idea of the fuzzy vault. Fuzzy vault is a recently developed cryptographic construct to secure critical data with the fingerprint data in a way that only the authorized user can access the secret by providing the valid fingerprint. We modify the fuzzy vault to protect fingerprint templates and to perform fingerprint verification with the protected template at the same time. This is challenging because the fingerprint verification is performed in the domain of the protected form. Based on the experimental results, we confirm that the proposed approach can perform the fingerprint verification with the protected template.

• 한국소음진동공학회논문집
• /
• 제21권11호
• /
• pp.1059-1066
• /
• 2011

The micro-perforated panel absorber(MPPA) is one of promising noise control elements because of its applicability to extreme environments where general porous materials cannot be used. Since the MPPA is inherently non-porous sound absorber, it can be a good candidate of acoustic protection system of a space launcher. The overall sound pressure level inside payload fairings of commercial launch vehicles is so high(around 140 dB OASPL) that the conventional linear impedance model cannot be directly applied to the design of the acoustic protection systems. In this paper an acoustic impedance models of a micro-perforated panel absorber at high sound pressure environment were reviewed and the use of the impedance on the practical design of MPPAs was addressed. The variation of absorption characteristics of MPPA was discussed according to the design parameters, e.g., perforation ratio, the minute hole diameter, the thickness of MPP and the incident sound pressure level.

• Clinical and Experimental Pediatrics
• /
• 제57권2호
• /
• pp.55-66
• /
• 2014

The 7-valent pneumococcal protein conjugate vaccine (PCV7) has been shown to be highly efficacious against invasive pneumococcal diseases and effective against pneumonia and in reducing otitis media. The introduction of PCV7 has resulted in major changes in the epidemiology of pneumococcal diseases. However, pneumococcal vaccines induce serotype-specific immunity, and a relative increase in non-vaccine serotypes has been reported following the widespread use of PCV7, leading to a need for extended serotype coverage for protection. PCV10 and PCV13 have been licensed on the basis of noninferiority of immunogenicity compared to a licensed conjugate vaccine. In this article, we aimed to review important data regarding the efficacy and effectiveness of the extended-coverage PCVs published or reported thus far and to discuss future implications for pneumococcal vaccines in Korea. After the introduction of PCV10 and PCV13, within a short period of time, evidence of protection conferred by these vaccines against invasive and mucosal infections caused by most of the serotypes included in the vaccines is accumulating. The choice of vaccine should be based on the changes in the dynamics of pneumococcal serotype distribution and diseases in the region where the vaccines are to be used. Continuous surveillance is essential for the appropriate use of pneumococcal vaccines and evaluation of the impact of PCVs on pneumococcal diseases.

• 한국멀티미디어학회논문지
• /
• 제10권6호
• /
• pp.754-759
• /
• 2007

Methodology of ontology building based on Web resources will not only reduce significantly the ontology construction period, but also enhance the quality of the ontology. Remarkable progress has been achieved in this regard, but they encounter similar difficulties, such as the Web data extraction and knowledge acquisition. This paper researches on the characteristics of ontology construction data, including dynamics, largeness, variation and openness and other features, and the fundamental issue of ontology construction - formalized representation method. Then, the key technologies used in and the difficulties with ontology construction are summarized. A software Model-OntoMaker (Ontology Maker) is designed. The model is innovative in two regards: (1) the improvement of generality: the meta learning machine will dynamically pick appropriate ontology learning methodologies for data of different domains, thus optimizing the results; (2) the merged processing of (semi-) structural and non-structural data. In addition, as known to all wetland researchers, information sharing is vital to wetland exploitation and protection, while wetland ontology construction is the basic task for information sharing. OntoMaker constructs the wetland ontologies, and the model in this work can also be referred to other environmental domains.

• 한국중재학회지:중재연구
• /
• 제9권1호
• /
• pp.115-137
• /
• 1999

The UNCITRAL, during its thirty-two session in 1999 discussed certain issues and problems identified in interactional commercial arbitration practice. The issues discussed include certain aspects if conciliation proceedings ; the legislative requirement of a written form for the arbitration agreement ; arbitability ; soverign immunity ; consolidation of more than one case into one arbitral proceedings ; confidentiality of information in arbitral proceedings ; rasing claims in arbitral proceedings for the purpose of set-off ; decisions by "turncated" arbitral tribunals liability of arbitrators ; power by the arbitral tribunal to award interest ; costs of arbitral proceedings ; enforceability of interim measures of protection ; and discretion to enforce an award that has been set aside in the state of origin. Among those issues discussed, most of States agreed that the issues relating to certain aspects of conciliation proceedings ; the legislative requirement of a written form for the arbitration agreement ; enforceability of interim measures of protection ; and discretion to enforce an award that has been set aside in the State of origin should have priority over other issues. The UNCITRAL may wish to consider the desirability of preparing uniform provisions on any of those issues, possibly indicating whether further work should be towards a legislative text (such as a model legislative provision or a treaty) or a non-legislative text (such as a model contractual rule).