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A Case Report of a Non-small Cell Lung Cancer Patient Metastasis to Vertebra with Cancer Pain Improved by Traditional Korean medicine including Aconitum Ciliare Decaisne Pharmacopuncture (비소세포성 폐암의 척추 전이로 발생한 암성통증에 대한 초오 약침을 포함한 한방 치료 1례)

  • Yoon, Mi-jung;Cho, Na-kyung;Lee, Yu-Ri;Choi, Hong-sic;Kim, Seung-Mo;Kim, Kyung-soon
    • Journal of Korean Traditional Oncology
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    • v.24 no.2
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    • pp.33-41
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    • 2019
  • Objectives : The purpose of this case report is to examine clinical application of Traditional Korean medicine including aconitum ciliare decaisne pharmacopuncture for cancer pain caused by bone metastasis of non small cell lung cancer. Methods : The patient diagnosed as non small cell lung cancer was treated with pharmacopuncture, acupuncture, electroacupuncture and herbal medicine. We used NRS(Numeric rating scale) and ECOG PS(Eastern Cooperative Oncology Group Performance Status) to observe the effect of the treatment. Results : After the treatment, NRS of cancer pain and ECOG PS score decreased. Also, the frequency of using rapid-onset opioids decreased. Conclusions : This study suggests Traditional Korean medicine treatment including aconitum ciliare decaisne pharmacopuncture is effective in cancer pain control caused by metastasis to bone with multiple organs with non small cell lung cancer.

Metformin Addition to Chemotherapy in Stage IV Non-Small Cell Lung Cancer: an Open Label Randomized Controlled Study

  • Sayed, Rana;Saad, Amr S;El Wakeel, Lamia;Elkholy, Engi;Badary, Osama
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.15
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    • pp.6621-6626
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    • 2015
  • Purpose: To evaluate effects of metformin on clinical outcome of non-diabetic patients with stage IV NSCLC. Materials and Methods: A prospective, randomized, open-label, controlled pilot study was conducted on patients with stage IV NSCLC with an Eastern Cooperative Oncology Group Performance Status (ECOG PS) of 0-2, excluding patients with diabetes and lactic acidosis. Thirty chemo-$na\ddot{i}ve$, non-diabetic patients with stage IV NSCLC were enrolled. Fifteen patients received intravenous gemcitabine/cisplatin regimen alone (arm B) while fifteen patients received the same regimen plus daily oral metformin 500mg (arm A). The effect of metformin on chemotherapy-response rates, survival, and adverse events in these patients was evaluated. Results: Objective response rate (ORR) and median overall survival (OS) in arms A and B were 46.7% versus 13.3% respectively, p=0.109 and 12 months versus 6.5 months, respectively, p=0.119. Median progression free survival (PFS) in arms A and B was 5.5 months versus 5 months, p=0.062. No significant increase in toxicity was observed in arm A versus arm B. Percentage of patients who experienced nausea was significantly lower in arm A versus arm B, at 26.7% versus 66.7% respectively, p=0.028. Conclusions: Metformin administration reduced occurrence of chemotherapy induced-nausea. Non-statistically significant improvements in the ORR or OS were observed. Metformin had no effect on PFS.

Iris Image Enhancement for the Recognition of Non-ideal Iris Images

  • Sajjad, Mazhar;Ahn, Chang-Won;Jung, Jin-Woo
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.10 no.4
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    • pp.1904-1926
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    • 2016
  • Iris recognition for biometric personnel identification has gained much interest owing to the increasing concern with security today. The image quality plays a major role in the performance of iris recognition systems. When capturing an iris image under uncontrolled conditions and dealing with non-cooperative people, the chance of getting non-ideal images is very high owing to poor focus, off-angle, noise, motion blur, occlusion of eyelashes and eyelids, and wearing glasses. In order to improve the accuracy of iris recognition while dealing with non-ideal iris images, we propose a novel algorithm that improves the quality of degraded iris images. First, the iris image is localized properly to obtain accurate iris boundary detection, and then the iris image is normalized to obtain a fixed size. Second, the valid region (iris region) is extracted from the segmented iris image to obtain only the iris region. Third, to get a well-distributed texture image, bilinear interpolation is used on the segmented valid iris gray image. Using contrast-limited adaptive histogram equalization (CLAHE) enhances the low contrast of the resulting interpolated image. The results of CLAHE are further improved by stretching the maximum and minimum values to 0-255 by using histogram-stretching technique. The gray texture information is extracted by 1D Gabor filters while the Hamming distance technique is chosen as a metric for recognition. The NICE-II training dataset taken from UBRIS.v2 was used for the experiment. Results of the proposed method outperformed other methods in terms of equal error rate (EER).

A Study on Policies to Increase the Income of Fishing Villages Focused on Non-fishing Income (어촌 소득 증대 방안에 관한 연구 : 어업외 소득을 중심으로)

  • Kim Sung-Gwi;Hong Jang-Won
    • The Journal of Fisheries Business Administration
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    • v.35 no.2
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    • pp.31-51
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    • 2004
  • The reduction of fishing grounds due to the establishment of EEZ system among China, Japan and Korea together with the depletion of fish resources by pollution of waters and successive reclamation projects along the east and the south coastal lines has made many problems in coastal communities including the decrease of population, the deepening aging phenomenon in the fishery society and the fall of relative income level compared with those of rural and urban residents. Especially, the income level of a fishing household is 90%. of a rural resident and 70% of a urban resident. The income of a fishing household consists of 55% of fishing income, 20% of a agricultural source, 20% of income from non-fishing areas, and 10% of transferred income. Compared with that of a Japanese fishing household which has more diverse income sources such as 62% of income coming from non-fishing areas through being hired in manufacturing firms, etc., that of Korean ones is highly dependent upon fishery and agriculture, so that the diversification of income sources is urgently needed, especially in non-fishing areas. This paper shows that as a model to upgrade fisherman's income level, firstly, it is necessary to enhance the value-added of fishing products through processing and new innovation of distribution process and, secondly, to promote tourism in fishing villages. To ascertain this model, a questionnaire survey to fishermen was carried out and showed that they expressed a strong support for the increase of income by the value-added process through processing and innovative distribution system and the active introduction of tourism in fishing villages. A case study on Gosan cooperative in Jeju was also introduced to identify the rationale of the suggested model and this study proved the validity of the model again. Conclusively speaking, to level up the fisherman's income requires the value- added activities through the introduction of product processing and new distribution system together with the introduction of marine tourism in fishing villages.

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A Case Report on the Improvement of Cancer Pain in a Patient with Metastatic Non-Small Cell Lung Cancer Through Herbal Medicine-based Integrative Cancer Treatment with Chemotherapy (항암화학요법과 병행한 한의기반 통합암치료를 통한 전이성 비소세포폐암 환자의 암성 통증 호전 증례보고)

  • Young-min Cho;Jae-ho Yang;Han-eum Joo;So-jeong Park;Ji-hye Park;Hwa-seung Yoo
    • The Journal of Internal Korean Medicine
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    • v.44 no.3
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    • pp.594-601
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    • 2023
  • Objective: To demonstrate an improvement in metastatic cancer pain and a decrease in tumor size in a patient with non-small cell lung cancer. Method: A 53-year-old female patient diagnosed with metastatic non-small cell lung cancer in August 2022 underwent integrative cancer treatment (ICT) for two months to decrease the tumor size and improve back pain from bone metastasis. The patient underwent chemotherapy with ICT. Radiologic outcomes were assessed by chest, abdomen, and pelvis computed tomography based on the Response Evaluation Criteria in Solid Tumors (RECIST) protocol. Clinical outcomes were assessed using National Cancer Institute Common Terminology Criteria for Adverse Event (NCI-CTCAE), Eastern Cooperative Oncology Group (ECOG), and a numeric rating scale (NRS). Result: During the two months of treatment, the NRS scores for back pain were improved, and the ECOG score improved from grade 2 to 1. The size and metabolic activity of the primary lung tumor decreased and underwent partial remission based on RECIST. No serious side effects of grade 3 or higher were noted on the NCI-CTCAE test. Conclusion: This case suggests that ICT may have a therapeutic effect for cancer pain and a synergetic effect with chemotherapy for metastatic non-small cell lung cancer.

A Study on the Non-Line-of-Sight Error Mitigation in Wireless Sensor Networks (무선 센서 네트워크 환경에서 Non-Line-of-Sight 오류 감소 방안에 관한 연구)

  • Kim, Woo-Jin;Kang, Chul-Gyu;Oh, Chang-Heon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2008.05a
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    • pp.873-875
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    • 2008
  • In sensor network, the elimination of NLOS information is a necessity to improve the accuracy of the localization. For this reason, we proposed an algorithm iteratively eliminating the NLOS information to enhance the accuracy of the localization of a tag location, and simulated the proposed algorithm to confirm the performance. The proposed algorithm can estimate the location of the error distance within 3.5m when it has 10 LOS coordinates with LOS information. In addition, it can enhance the accuracy according to decreasing NLOS coordinates.

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A Study on Securities of Cryptosystems for Hierarchic Groups (위계집단에서 효율적인 암호계의 안전성에 관한 소고)

  • Kim, Yong-Tae
    • The Journal of the Korea institute of electronic communication sciences
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    • v.8 no.4
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    • pp.605-610
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    • 2013
  • A cryptography for enforcing hierarchic groups in a system where hierarchy is represented by a partially ordered set was introduced by Akl et al. But the key generation algorithm of Akl et al. is infeasible when there is a large number of users. To overcome this shortage, in 1985, MacKinnon et al. proposed a paper containing a condition which prevents cooperative attacks and optimizes the assignment. In 2005, Kim et al. proposed the key management systems for using one-way hash function, RSA algorithm, poset dimension and Clifford semigroup in the context of modern cryptography, the key management system using Clifford semigroup of imaginary quadratic non-maximal orders. We, in this paper, show that Kim et al. cryptosystem is insecure in some reasons and propose a revised cryptosystem.

Industrial Application of Embryo Transfer in Korea (수정란이식의 산업화 방안)

  • 정길생
    • Korean Journal of Animal Reproduction
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    • v.7 no.2
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    • pp.41-52
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    • 1983
  • Animal in dustry in Korea urgently needs the domestic introduction and the industrial a, pp.ication of embryo transfer technique. Namely, this technique can be utilized effectively, as means of the improvement of livestocks, as means of the increase of meat production, as means of substitute for the livestock import, and dissemination of new breed. However, as this technique avaliable in our country is remaining initial stage, we can not make use of the technique industrially unless we make much improvement as follows; induction of superovulation, non-surgical recovery of embryos, synchronization between the estrus such cycles of donor and recipient, non-surgical transfer of embryos, etc. Simultaneously, the basic studies such as harvesting oocytes from ovary, in vitro culture of oocytes, in vitro capacitation of spermatozoa, cloning by culture of blastomeres and transfer of nuclei, sexing embryo, etc. should not be neglected in order to make the technique of embryo transfer more simple and convenient. For the success of these studies, universities, national and public institutes, large scale cattle farms, and small scale cattle farms should cooperate each other. For instance, universities undertake basic researches, and the national and public institutes a, pp.y the results of the researches to animal industry along with cooperation by large scale cattle farms. By the help of the cooperative organizations, the technique relevant to our environment and farm condition may be able to be finalized, and to be a, pp.ied to samll scale cattle farm. Consequently, being served to stimulate animal productivity, this technique can be contributed to the development of livestock industry in Korea.

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A Study on the Wearing Conditions of Summer School Uniform and Comfortable Uniform for Middle School Students - Focusing on Iksan city - (중학생의 여름철 교복 및 생활복 착용 실태에 관한 연구 - 익산지역을 중심으로 -)

  • Kim, Yun Hee;Lee, Jin Hee
    • Korean Journal of Human Ecology
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    • v.23 no.5
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    • pp.919-928
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    • 2014
  • The purpose of this study was conducted to improve middle school students' satisfaction on their uniform to provide basic information for the wearing condition. on their comfortable uniform. Survey was conducted on 532 boys' and girls' middle school students in Iksan City. This study analyzed the purchasing factors and modification, fitting evaluation, and satisfaction of comfortable uniform aspect of students. It was the questionnaire consisted of 18 questions in total. The results are as follows : First, boys' middle school students preferred 'activity' among the purchasing factors. Girls' middle school students preferred 'design' and 'activity' among the purchasing factors. Second, in purchasing types, boys' students bought the type of cooperative purchasing and the type of the school uniform special shop in girls' students. Third, 51.0% of the students interviewed have experienced to modify their uniforms. Since the non fashionable design and non suitable uniform length caused the students to modify their uniform. Also students did not satisfy the color and design in their comfortable uniforms. Thus school uniform maker should make that consider movement, color, design, functional elements and changing students' aesthetic sense.

Two-module robotic pipe inspection system with EMATs

  • Lee, Jin-Hyuk;Han, Sangchul;Ahn, Jaekyu;Kim, Dae-Hyun;Moon, Hyungpil
    • Smart Structures and Systems
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    • v.13 no.6
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    • pp.1041-1063
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    • 2014
  • This work introduces a two-module robotic pipe inspection system with ultrasonic NDE device to evaluate the integrity of pipe structures. The proposed robotic platform has high mobility. The two module mobile robot platform overcomes pipe obstacle structures such as elbow, or T-branch joints by cooperative maneuvers. Also, it can climb up the straight pipeline at a fast speed due to the wheel driven mechanism. For inspection of pipe structure, SH-waves generated by EMAT are applied with additional signal processing methods. A wavelet transform is implemented to extract a meaningful and specific signal from the superposed SH-wave signals. Intensity ratio which is normalized the defect signals intensity by the maximum intensity of directly transmitted signals in the wavelet transforms spectrum is applied to evaluate defects quantitatively. It is experimentally verified that the robotic ultrasonic inspection system with EMAT is capable of non-destructive inspection and evaluation of defects in pipe structure successfully by applying signal processing method based on wavelet transform.