• Title/Summary/Keyword: non-consecutive analysis

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Non-linear incidental dynamics of frame structures

  • Radoicic, Goran N.;Jovanovic, Miomir Lj.;Marinkovic, Dragan Z.
    • Structural Engineering and Mechanics
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    • v.52 no.6
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    • pp.1193-1208
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    • 2014
  • A simulation of failures on responsible elements is only one form of the extreme structural behavior analysis. By understanding the dynamic behavior in incidental situations, it is possible to make a special structural design from the point of the largest axial force, stress and redundancy. The numerical realization of one such simulation analysis was performed using FEM in this paper. The boundary parameters of transient analysis, such as overall structural damping coefficient, load accelerations, time of load fall and internal forces in the responsible structural elements, were determined on the basis of the dynamic experimental parameters. The structure eigenfrequencies were determined in modal analysis. In the study, the basic incidental models were set. The models were identified by many years of monitoring incidental situations and the most frequent human errors in work with heavy structures. The combined load models of structure are defined in the paper since the incidents simply arise as consequences of cumulative errors and failures. A feature of a combined model is that the single incident causes the next incident (consecutive timing) as well as that other simple dynamic actions are simultaneous. The structure was observed in three typical load positions taken from the crane passport (range-load). The obtained dynamic responses indicate the degree of structural sensitivity depending on the character of incident. The dynamic coefficient KD was adopted as a parameter for the evaluation of structural sensitivity.

Impact of Postoperative Chemoradiotherapy and Chemoradiotherapy Alone for Esophageal Cancer in North-West Iran

  • Mirinezhad, Seyed Kazem;Somi, Mohammad Hossein;Shirmohamadi, Masoud;Seyednejad, Farshad;Jangjoo, Amir Ghasemi;Ghojazadeh, Morteza;Mohammadzadeh, Mohammad;Naseri, Ali Reza;Nasiri, Behnam
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.6
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    • pp.3921-3924
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    • 2013
  • Background: To investigate the role of surgical treatment for locally advanced esophageal cancer, we compared the outcomes of chemoradiotheroy alone (CRT) to postoperative chemoradiotherapy (S/CRT), using, Regional Radiotherapy Center, database. Materials and Methods: This retrospective study was conducted in North-West of Iran, included of 255 consecutive patients with esophageal cancer. Eligible operable and non-operable, were treated with S/CRT and CRT respectively. Radiotherapy (RT) was delivered at 1.8-2 Gy/day for five consecutive days in a given week. Chemotherapy (CT) consisted of cisplatin and 5-fluorouracil. Results: From March 2006 to March 2011 255 patients: male/female 129/96, median age 68 (35-90), squamous/adeno 213/12, received CRT/S+CRT 166/59, median radiation dose $45{\pm}13.6Gy$, Median survival 13.5 (11-15), overall survival (OS) One/Two/Three 57/21/16%, Died/alive 158/97, Univariate analysis prognostic factors: age/stag/differentiation/dose of RT/fraction/treatment, Multivariate analysis predictor factor: dose of RT/fraction. Conclusions: Although this treatment offers some possibility for improvement of patients with esophageal cancer, there remains a significant need for development of new drug and new therapeutic approaches that can substantially impact survival.

Outcomes of Non-Operative Management for Pseudarthrosis after Pedicle Subtraction Osteotomies at Minimum 5 Years Follow-Up

  • Kim, Yong-Chan;Kim, Ki-Tack;Kim, Cheung-Kue;Hwang, Il-Yeong;Jin, Woo-Young;Lenke, Lawrence G.;Cha, Jae-Ryong
    • Journal of Korean Neurosurgical Society
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    • v.62 no.5
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    • pp.567-576
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    • 2019
  • Objective : Minimal data exist regarding non-operative management of suspected pseudarthrosis after pedicle subtraction osteotomy (PSO). This study reports radiographic and clinical outcomes of non-operative management for post-PSO pseudarthrosis at a minimum 5 years post-detection. Methods : Nineteen consecutive patients with implant breakage indicating probable pseudarthrosis after PSO surgery (13 women/six men; mean age at surgery, 58 years) without severe pain and disability were treated with non-operative management (mean follow-up, 5.8 years; range, 5-10 years). Non-operative management included medication, intermittent brace wearing and avoidance of excessive back strain. Radiographic and clinical outcomes analysis was performed. Results : Sagittal vertical axis (SVA), proximal junctional angle, thoracic kyphosis achieved by a PSO were maintained after detection of pseudarthrosis through ultimate follow-up. Lumbar lordosis and PSO angle decreased at final follow-up. There was no significant change in Oswestry Disability Index (ODI) scores and Scoliosis Research Society (SRS) total score, or subscales of pain, self-image, function, satisfaction and mental health between detection of pseudarthrosis and ultimate follow-up. SVA greater than 11 cm showed poorer ODI and SRS total score, as well as the pain, self-image, and function subscales (p<0.05). Conclusion : Non-operative management of implant failure of probable pseudarthrosis after PSO offers acceptable outcomes even at 5 years after detection of implant breakage, provided SVA is maintained. As SVA increased, outcome scores decreased in this patient population.

Contact analysis of spherical ball and a deformable flat model with the effect of tangent modulus

  • Sathish Gandhi, V.C.;Ramesh, S.;Kumaravelan, R.;Thanmanaselvi, M.
    • Structural Engineering and Mechanics
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    • v.44 no.1
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    • pp.61-72
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    • 2012
  • The paper is on contact analysis of a spherical ball with a deformable flat, considering the effect of tangent modulus on the contact parameters of a non-adhesive frictionless elastic-plastic contact. The contact analysis of this model has been carried out using analysis software Ansys and Abaqus. The contact parameters such as area of contact between two consecutive steps, volume of bulged material are evaluated from the formulated equations. The effect of the tangent modulus is considered for determining these parameters. The tangent modulus are accounted between 0.1E and 0.5E of materials E/Y value greater than 500 and less than 1750. Result shows that upto an optimal tangent modulus values the elastic core push up to the free surface in the flat. The simulation is also carried out in Abaqus and result provide evidence for the volume of bulged material in the contact region move up and flow into the free surface of the flat from the contact edge between the ball and flat. The strain energy of the whole model is varied between 20 to 40 percentage of the stipulated time for analysis.

New phenomena associated with the nonlinear dynamics and stability of autonomous damped systems under various types of loading

  • Sophianopoulos, Dimitris S.
    • Structural Engineering and Mechanics
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    • v.9 no.4
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    • pp.397-416
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    • 2000
  • The present study deals with the nonlinear dynamics and stability of autonomous dissipative either imperfect potential (limit point) systems or perfect (bifurcational) non-potential ones. Through a fully nonlinear dynamic analysis, performed on two simple 2-DOF models corresponding to the classes of systems mentioned above, and with the aid of basic definitions of the theory of nonlinear dynamical systems, new important phenomena are revealed. For the first class of systems a third possibility of postbuckling dynamic response is offered, associated with a point attractor on the prebuckling primary path, while for the second one the new findings are chaos-like (most likely chaotic) motions, consecutive regions of point and periodic attractors, series of global bifurcations and point attractor response of always existing complementary equilibrium configurations, regardless of the value of the nonconservativeness parameter.

Rayleigh-Quotient and Iterative-Threshold-Test-Based Blind TOA Estimation for IR-UWB Systems

  • Shen, Bin;Zhao, Chengshi;Cui, Taiping;Kwak, Kyung-Sup
    • ETRI Journal
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    • v.32 no.2
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    • pp.333-335
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    • 2010
  • This letter proposes a non-coherent blind time-of-arrival (TOA) estimation scheme for impulse radio ultra-wideband systems. The TOA estimation is performed in two consecutive phases: the Rayleigh-quotient theorem-based coarse-signal acquisition (CSA) and the iterative-threshold-test-based fine time estimation (FTE). The proposed scheme serves in a blind manner without demanding any a priori knowledge of the channel and the noise. Analysis and simulations demonstrate that the proposed scheme significantly increases the signal detection probability in CSA and ameliorates the TOA estimation accuracy in FTE.

Wireless monitoring of typhoon-induced variation of dynamic characteristics of a cable-stayed bridge

  • Park, Jae-Hyung;Huynh, Thanh-Canh;Kim, Jeong-Tae
    • Wind and Structures
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    • v.20 no.2
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    • pp.293-314
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    • 2015
  • In this paper, wireless monitoring of typhoon-induced variation of dynamic characteristics of a cable-stayed bridge is presented. Firstly, cable-stayed bridge with the wireless monitoring system is described. Wireless vibration sensor nodes are utilized to measure accelerations from bridge deck and stay cables. Also, modal analysis methods are selected to extract dynamic characteristics. Secondly, dynamic responses of the cable-stayed bridge under the attack of two typhoons are analyzed by estimating relationships between wind velocity and dynamic characteristics. Wind-induced variations of deck and cable vibration responses are examined based on the field measurements under the two consecutive typhoons, Bolaven and Tembin. Finally, time-varying analyses are performed to investigate non-stationary random properties of the dynamic responses under the typhoons.

Effect of ozone treatment on the expression of a foreign gene in transgenic poplar subclones (형질전환 포플라 subclone의 도입유전자 발현에 대한 오존처리의 영향)

  • 설일환;신동일
    • Journal of Life Science
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    • v.7 no.3
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    • pp.172-175
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    • 1997
  • Transgenic hybrid poplar subclones containing herbicide glyphosate resistant gene (aroA) were treated with ozone at the concentration of 100 nL L$^{-1}$ for 6 hr for 5 consecutive days. The foreign gene expression in leaves of all treated plants was reduced both at transcriptional and translational levels confirmed by Northern and Western blot analysis, respectively, as compared to non-treated control plants. These results indicated that the expression of foreign gene in transgenic plants could be affected by the environmental stresses. Thus, the performance of transgenic plants cultivated on field conditions may be lower than they are expected.

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Differences in the Prognostic Significance of the SUVmax between Patients with Resected Pulmonary Adenocarcinoma and Squamous Cell Carcinoma

  • Motono, Nozomu;Ueno, Masakatsu;Tanaka, Makoto;Machida, Yuichiro;Usuda, Katsuo;Sakuma, Tsutomu;Sagawa, Motoyasu
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.23
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    • pp.10171-10174
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    • 2015
  • Background: The purpose of this study was to determine the prognostic significance of the maximum standardized uptake value (SUVmax) on F-18-fluorodeoxyglucose (FDG)-positron emission tomography (PET) in patients undergoing surgical treatment for non-small cell lung cancer. Materials and Methods: Seventy-eight consecutive patients (58 with adenocarcinomas, 20 with squamous cell carcinomas) treated with potentially curative surgery were retrospectively reviewed. Results: The SUVmax was significantly higher in the patients with recurrent than with non-recurrent adenocarcinoma (p<0.01). However, among the patients with squamous cell carcinoma, there were no differences with or without recurrence (p=0.69). Multivariate analysis indicated that the SUVmax of adenocarcinoma lesions was a significant predictor of disease-free survival (p=0.04). In addition, an SUVmax of 6.19, the cut-off point based on ROC curve analysis of the patients with pathological IB or more advanced stage adenocarcinomas, was found to be a significant predictor of disease-free survival (p<0.01). Conclusions: SUVmax is a useful predictor of disease-free survival in patients with resected adenocarcinoma, but not squamous cell carcinoma. Patients with adenocarcinoma exhibiting an SUVmax above 6.19 are candidates for more intensive adjuvant therapy.

Allergic risk assessment of genetically modified cucumber mosaic virus resistant pepper (유전자변형 바이러스 저항성 고추의 알레르기 안전성)

  • Son, Dae-Yeul
    • Food Science and Preservation
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    • v.22 no.6
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    • pp.901-907
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    • 2015
  • Genetically modified (GM) pepper H15 containing the gene for cucumber mosaic virus (CMV) coat protein (CP) and its control line non-GM pepper P2377 were investigated for their allergic risk. Amino acid sequence of the inserted gene product CMV-CP was compared with those of known allergens. No known allergen had greater than 35% amino acid sequence homology over an 80 amino acid window or more than 8 consecutive identical amino acids. Protein patterns of GM and non-GM pepper extracts were evaluated by SDS-PAGE, which showed similar distribution of protein bands for both GM and non-GM pepper. Antigen-antibody reactions were compared between GM and its non-transgenic parental control. ELISA and immunoblot analysis of sera from allergic patients showed some IgE reactivity; however, no differences were observed between GM pepper H15 and P2377. We therefore conclude that CMV-CP is less likely to be an allergen; the protein composition and allergenicity of the GM pepper H15 is not different from that of P2377 and safe as a commercial host.