• 대한방사선기술학회지:방사선기술과학
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• 제28권3호
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• pp.211-217
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• 2005

본 연구에서는 건강검진센터에서 임상적 증상 없이 갑상선 초음파를 시행 한 30대-70대 838명을 대상으로 갑상선 결절(thyroid nodule) 유무와 연령 및 성별에 의한 결절의 수, 결절의 크기, 결절의 발생 부위 등을 분석하여 다음과 같은 결론을 얻었다. 1. 연구 대상자 838명의 일반적 특성은 남자가 368명(44%), 여자가 470명(56%)이었으며 평균 연령은 51세 이었다. 2. 전체 대상자 838명 중 정상으로 진단된 경우는 590명(70%), 결절이 있는 유소견자는 248명(30%)으로 평균 30%의 갑상선 결절 유소견을 보였다. 3. 갑상선 결절의 연령대별 빈도는 $30{\sim}40$대 남자 $10%{\sim}14%$, 여자 $20{\sim}29%$, $50{\sim}60$대 남자 $27{\sim}33%$, 여자 $37{\sim}52%$, 70대 남자 46%, 여자 50%로 나타났다. 4. 갑상선 결절 유소견자 248명을 단일성 결절(solitary nodule)과 다발성 결절(multiple nodule)로 구분한 결과 단일성은 125명으로 50.5%, 다발성은 49.5%를 보여 거의 같은 비율로 나타나고 있다. 5. 갑상선 결절의 크기는 모든 연령층에서 대부분 작은 크기의 결절을 가지고 있었으며 $1{\sim}10\;mm$의 크기가 유소견자 248명 중 187명(75%)으로 가장 많았고 $11{\sim}20\;mm$는 45명(18%), $21{\sim}30\;mm$는 14명(5.6%), 31 mm이상은 2명이었다. 6. 결절의 해부학적 발생부위는 우엽 93명(38%), 좌엽 67명(27%), 양엽 75명(30%), 협부 13명(5.3%)으로 나타나 우엽에 가장 많은 빈도를 보이고 있으며 협부에는 적게 발견되었다.

• Ocean and Polar Research
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• 제36권4호
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• pp.373-381
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• 2014

Korea contract Mn-nodule field in the NE equatorial Pacific is composed of seven sectors with average water depths of 4,513-5,025 m. Of the various factors controlling the properties of Mn-nodule, it seems that water depth is likely connected to the chemical composition and occurrence of nodules. To test whether such an assumption held in each sector, we reviewed previous research data accumulated since 1994 for one of the northern sectors (hereafter KR1) where there are stark contrasts in water depth. High-resolution seabed mapping clearly separates a northern part (KR1N) from a deeper southern part (KR1S), cutting across in the middle of the KR1. In addition, significant volcanic activities forming numerous seamounts are distinctive especially in KR1N. In terms of nodule occurrence, manganese nodules in KR1S are comparatively larger (2-4 cm) with a discoidal shape, while those in KR1N are generally small (<2 cm) with poly-lobate and irregular shapes. Nodules in KR1N also have lower Co, Cu, Mn and Ni, and higher Fe contents. The spatial separation in nodule characteristics might be caused by volcanic activities in KR1N rather than water depth contrast. During the formation of the seamounts in KR1N, rock fragments and volcanic ashes as new nuclei of the nodules would have been continuously generated. As a result, the nodules could not grow larger than 2 cm and display the shapes of a newbie (i.e., irregular and poly-lobate shapes). Moreover, significant Fe supply from volcanic activities probably decreases the Mn/Fe ratio, which may lead to the KR1 nodules being misinterpreted as a hydrogenic in origin compared to other sectors where a high Mn/Fe ratio is present.

• 대한두경부종양학회지
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• 제8권2호
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• pp.82-90
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• 1992

A pathologic review was made of 1547 cases of thyroid nodule during the 20 years from 1970 to 1989 at the department of Head and Neck surgery of Presbyterian Medical Center in Chonju. 1547 cases were analysed in regard to cancer incidence of thyroid nodule, correlation of preoperative diagnosis with pathology and of frozen section diagnosis with final pathology, surgical procedures employed in managing thyroid itself, location of metastatic nodes, further definite procedure in cnacer cases, effectiveness of prophylactic neck dissection with lymph node pathology. The results are summarized as follows: 1) The cancer incidence of thyroid nodule was 21.7%. 2) The incidence of thyroid cnacer in total neoplasms increased from 1.6% to 2.9%. 3) The thyroid cancer was prevalent in female(5.9:1) and in fifth, fourth and sixth decade of life. 4) The incidence of solitary cold nodule in thyroid cancer was 72.7% (210/289). S) The incidence of thyroid cancer in solitary cold nodule was 28.7% (210/782). 6) The false negative of frozen section (1240 cases) was 19.8%. 7) Histologically, well differentiated carcinoma comprises about 94% of all cases and papillary carcinoma was 78.5% of all cases 8) The most frequent lymphatic metastasis was pre- & paratrachel nodes(63.3%), followed by Level III(50%) and Level II(47.7%). 9) 47.7% among 130 cases of papillary adenocarcinoma and 12.5% among 16 cases of follicular adenocarcinoma, each group treated with prophylactic neck dissection, were confirmed to be occult cervical node metastasis.

• 대한두경부종양학회지
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• 제15권1호
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• pp.66-69
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• 1999

Background and Objectives: It is critical to distinguish benign from malignant thyroid nodule and to select a patient for surgery. Even though the U/S study dose not make great contribution to diagnose a malignant thyroid nodule, it is widely used in the evaluation of anatomic feature of thyroid. The authors tried to estimate the efficacy of the U/S study in preoperative diagnosis of malignant thyroid nodule. Materials and Method: At the department of General Surgery of Ajou University, 75 patients who were operated after diagnosis with thyroid nodule by U/S study between July 1996 to June 1997 were retrospectively analyzed. By comparing the U/S impression that implies malignant thyroid nodule to FNAC and post-operative pathologic results ware as follows. Results: 1) Absence of cystic change, presence of internal hypoechogenicity, lobulation, calcification, thick and irregular halo, and nodule more than 4cm in diameter on U/S were considered significant statistically for the diagnosis of malignancy(Chi-square test, p<0.05) 2) Presence of internal hypoechogenicity or thick and irregular halo has the validity in Logistic regression analysis. 3) FNAC was done in 65 case. 19 case were malignant, 11 case were suspicious and 46 patients were benign (sensitivity 52.6%, specificity 87%). 4) The findings of U/S which are hypoechogenic and thick and irregular halo show 82% sensitivity and 97% specificity. In combination with the findings of FNAC that imply benign or suspicious lesions, the sensitivity was 100% and the specificity was 97%. Conclusion: This study suggest that the hypoechogenicity and thick and irregular halo on U/S are important information for the diagnosis of thyroid malignancy which were considered benign or suspicious after FNAC.

• 한국작물학회지
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• 제24권2호
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• pp.75-81
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• 1979

우리나라 장여품종을 위함한 15개 대두품종들의 근류균에 대한 친화성과 접종효과를 밝히기 위하여 사경시험을 실시하였던 바 그 얻어진 결과를 요약하면 다음과 같다. 1. 정석은 근류균접종 15일후에도 근류가 형성되지 않았으나 Lindarin #62는 주당 3.0개의 근류가 형성 되었으며 개화기의 근류형성수도 품종간에 크게 차이가 있어서 정석은 주당 37.8대로 가장 적었고 Haman은 주당 122.2개로 가장 많이 형성되었는데 품종간에 유의차가 인정되었다. 2. 개화기까지의 근류형성수에 대한 시기별 근류형성비율은 품종간에 크게 차이가 있었는데 공시품종평균에 있어서는 접종 15일후에 2,1％, 접종30일후에는 60.8％, 그리고 접종 45일후에는 79.8％가 형성되었다. 3. 근류병접종효과는 현저하여 초장, 경태, 근장, 건물중 및 엽록소함량이 무접종구에 비하여 접종구가 크게 증가하여 전체처리 및 품종간, 그리고 접종처리간에 고도로 유의하였는데 다만 엽록소함량과 건물중의 증가추세와는 반드시 일치되지 않았다. 4. 공시품종평균에 있어서 접종구에 대한 무접종구의 몇가지 현질의 형성비율은 초장 94.0％, 건물중 81.6％, 그리고 엽록소의 함량은 66.8％였다.

• 한국물환경학회지
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• 제22권1호
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• pp.116-121
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• 2006

Fundamental investigations have been carried out to find the applicability of manganese nodule as an adsorbent of nickel ion with an intention that nickel can be secured in manganese nodule along with the treatment of wastewater. The average content of manganese in nodules which used in the experiments was about 27%. The content of nickel in manganese nodules was observed to increase up to 4 times higher with comparison to its original value after adsorption. When the initial concentration of nickel ion in artificial wastewater was lower than 500 mg/L, its adsorbed amount on manganese nodule was shown to increase continuously. However, no more than about 82 mg/L of nickel was attained at higher initial nickel ion concentration than 500 mg/L. The adsorption of nickel ion was increased with temperature under experimental conditions and as the size of manganese nodule particles became smaller more nickel ion was adsorbed on adsorbent. Regarding the effect of pH, the adsorption of nickel ion was more hindered as the solution became acidic. Adsorption behavior of nickel ion on manganese nodule was found to follow the Freundlich model well and kinetic analysis showed that the adsorption reaction of nickel ion was second order. Thermodynamic parameters for the nickel ion adsorption were estimated on the basis of thermodynamic equations and they were in good agreement with experimental results.

• 대한기관식도과학회:학술대회논문집
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• 대한기관식도과학회 1983년도 제17차 학술대회연제순서 및 초록
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• pp.6.2-6
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• 1983

이비인후과 영역의 종양중 후두종양은 비교적 흔히 볼 수 있으며, 그 특이한 증상과 간접후두경 및 후두직달경 등으로 조기진단이 가능한 반면에 증상의 경과도 빨라 치명율 역시 높은 것이 사실이다. 이에 저자는 1978년 6월부터 1983 년 2월까지 본 병원에 내원하여 애성 및 후두종양을 발견한 108명의 환자를 임상적 및 병리학적으로 분류하여 문헌적 고찰과 함께 보고하는 바이다.

• 대한후두음성언어의학회지
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• 제12권2호
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• pp.133-139
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• 2001

Background and Objectives : There are so many methods to investigate the causes of voice disorders. However, they were almost invasive or non-physiologic methods. And none of them showed the laryngeal movements. Phonation pharyngogram is non-invasive method to see the laryngeal movement directly. Authors studied to evaluate the availability of phonation pharyngogram in laryngeal nodule. Materials and Methods : 30 laryngeal nodules and 10 control groups were evaluated. Acoustic analysis and maximum phonation time were measured and pharyngogram was taken during sustaining /a/ phonation immediately after swallowing the barium. We measured the width of hypopharyngeal wall, shape of hypopharyngeal wall and pyriform sinus apex, level difference between both true vocal folds, angle of subglottis, location of true vocal folds, elevated distance of vocal folds and shape of c-spine. Results : Jitter, Shimmer of laryngeal nodule were higher than control group and maximum phonation time was shorter in laryngeal nodule. There was a significance in width of hypopharyngeal wall, shape of pyriform sinus apex, level difference between both true vocal folds, elevated distance of vocal folds and shape of c-spine. Conclusions : Authors knew that there were differences when we used the phonation pharyngogram between normal group and laryngeal nodule group.

• Parasites, Hosts and Diseases
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• 제51권4호
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• pp.467-470
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• 2013

The present study reports a human case of cutaneous gnathostomiasis with recurrent migratory nodule and persistent eosinophilia in China. A 52-year-old woman from Henan Province, central China, presented with recurrent migratory reddish swelling and subcutaneous nodule in the left upper arm and on the back for 3 months. Blood examination showed eosinophila (21.2%), and anti-sparganum antibodies were positive. Skin biopsy of the lesion and histopathological examinations revealed dermal infiltrates of eosinophils but did not show any parasites. Thus, the patient was first diagnosed as sparganosis; however, new migratory swellings occurred after treatment with praziquantel for 3 days. On further inquiring, she recalled having eaten undercooked eels and specific antibodies to the larvae of Gnathostoma spinigerum were detected. The patient was definitely diagnosed as cutaneous gnathostomiasis caused by Gnathostoma sp. and treated with albendazole (1,000 mg/day) for 15 days, and the subsequent papule and blister developed after the treatment. After 1 month, laboratory findings indicated a reduced eosinophil count (3.3%). At her final follow-up 18 months later, the patient had no further symptoms and anti-Gnathostoma antibodies became negative. Conclusively, the present study is the first report on a human case of cutaneous gnathostomiasis in Henan Province, China, based on the past history (eating undercooked eels), clinical manifestations (migratory subcutaneous nodule and persistent eosinophilia), and a serological finding (positive for specific anti-Gnathostoma antibodies).

• Ocean and Polar Research
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• 제36권4호
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• pp.515-524
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• 2014

The Korea Institute of Ocean Science and Technology has acquired detailed biological, chemicophysical, and geological data in the northeastern Pacific through a manganese nodule program since 1983. Plenty of manganese nodules were collected to estimate the amount of resources by free-fall grab and box corer. The collected manganese nodules have been archived systematically in the rock and mineral storage section of the Library of Marine Samples (LIMS) since 2012. The LIMS provides essencial information on the stored samples including sample name, nodule type, sampling location, depth, and equipment. Although a high quality database of the information system is under construction, the samples have tagged information for manganese nodules like chemical composition, morphology, weight, size, abundance, and photograph. In this study, we attempted to provide information on the well-organized and easily accessible archived manganese nodule samples for future studies and to introduce the usefulness of the LIMS.