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Bayesian Estimation in Bioequivalence Study

  • Lee, Seung-Chun
    • The Korean Journal of Applied Statistics
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    • v.24 no.6
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    • pp.1095-1102
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    • 2011
  • The classical two-period, two-sequence crossover design is no longer sufficient to assess various demands in a bioequivalence study. For instance, to estimate the within-subject and between-subject variances of test and reference formulations separately, it is necessary to use a replicate design in which each subject receives at least the reference formulation in two periods. Several designs were studied to satisfy the demands. It is provided a unified Bayesian approach applicable to those study designs. The benefit of the method in the bioequivalence study is discussed.

A Design and Implementation of Real-time Video frame data Processing control for Block Matching Algorithm (고속블럭정합 알고리즘을 위한 실시간 영상프레임 데이터 처리 제어 방법의 설계 및 구현)

  • 이강환;황호정
    • Proceedings of the IEEK Conference
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    • 2001.06b
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    • pp.373-376
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    • 2001
  • This paper has been studied a real-time video frame data processing control that used the linear systolic array for motion estimation. The proposed data control processing provides to the input data into the multiple processor array unit(MPAU) from search area and reference block data. The proposed data control architecture has based on two slice band for input data processing. And it has no required external control logic blocks for input data as like reference block or search area data.

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Model Reference Adaptive Control for Linear System with Improved Convergence Rate-parameter Adaptation Method (선형시스템을 위한 개선된 수렴속도를 갖는 기준모델 적응제어)

  • Lim, Kye-Young
    • The Transactions of the Korean Institute of Electrical Engineers
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    • v.37 no.12
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    • pp.884-893
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    • 1988
  • Adaptive controllers for linear unknown coefficient system, that is corrupted by disturbance, are designed by parameter adaptation model reference adaptive control(MRAC). This design is stemmed from the Lyapunov direct method. To reduce the model following error and to improve the convergence rate of the design, an indirect-suboptimal control law is derived. Proper compensation for the effects of time-varying coefficients and plant disturbance are suggested. In the design procedure no complete identification of unknown coefficients are required.

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Model Reference Adaptive Control for Linear System with Improved Convergence Rate -SIGNAL SYNTHESIS METHOD- (선형시스템을 위한 개선된수렴속도를 갖는 기준모델 적응제어기- SYNTHESIS METHOD)

  • Lim, Kye-Young
    • The Transactions of the Korean Institute of Electrical Engineers
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    • v.37 no.10
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    • pp.733-739
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    • 1988
  • Adaptive controllers for linear system whose nominal values of coefficients only are known, that is corrupted by disturbance, are designed by signal synthesis model reference adaptive control (MRAC). This design is stemmed from the Lyapunov direct method. To reduce the model following error and to improve the conrergence rate of the design, an indirect suboptimal control law is de rived using the Hamilton Jacobi Beellman equation. Proper compensaton for the effects of time varying coefficients and plant disturbance are suggested. In the design procedure no complete identification of unknown coefficients are required.

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Wind Load Assumption of 765Kv Transmission Towers

  • Kim, Jeong-Boo
    • Journal of Electrical Engineering and information Science
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    • v.1 no.1
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    • pp.45-50
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    • 1996
  • This paper mainly describes the wind load assumption of 765kV transmission towers. We analyzed wind velocity data a meteorological observatories to get the wind velocity of 50 years return period by using Gumbel I type extreme value distribution. By multi-correlative regression analysis method, wind velocity at no observation site was obtained. Reference dynamics wind pressure map was obtained from above analysis and the wind pressure was classified as three regio in high temperature season.

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Phantom-Validated Reference Values of Myocardial Mapping and Extracellular Volume at 3T in Healthy Koreans

  • Lee, Eunjin;Kim, Pan Ki;Choi, Byoung Wook;Jung, Jung Im
    • Investigative Magnetic Resonance Imaging
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    • v.24 no.3
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    • pp.141-153
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    • 2020
  • Purpose: Myocardial T1 and T2 relaxation times are affected by technical factors such as cardiovascular magnetic resonance platform/vendor. We aimed to validate T1 and T2 mapping sequences using a phantom; establish reference T1, T2, and extracellular volume (ECV) measurements using two sequences at 3T in normal Koreans; and compare the protocols and evaluate the differences from previously reported measurements. Materials and Methods: Eleven healthy subjects underwent cardiac magnetic resonance imaging (MRI) using 3T MRI equipment (Verio, Siemens, Erlangen, Germany). We did phantom validation before volunteer scanning: T1 mapping with modified look locker inversion recovery (MOLLI) with 5(3)3 and 4(1)3(1)2 sequences, and T2 mapping with gradient echo (GRE) and TrueFISP sequences. We did T1 and T2 mappings on the volunteers with the same sequences. ECV was also calculated with both sequences after gadolinium enhancement. Results: The phantom study showed no significant differences from the gold standard T1 and T2 values in either sequence. Pre-contrast T1 relaxation times of the 4(1)3(1)2 protocol was 1142.27 ± 36.64 ms and of the 5(3)3 was 1266.03 ± 32.86 ms on the volunteer study. T2 relaxation times of GRE were 40.09 ± 2.45 ms and T2 relaxation times of TrueFISP were 38.20 ± 1.64 ms in each. ECV calculation was 24.42% ± 2.41% and 26.11% ± 2.39% in the 4(1)3(1)2 and 5(3)3 protocols, respectively, and showed no differences at any segment or slice between the sequences. We also calculated ECV from the pre-enhancement T1 relaxation time of MOLLI 5(3)3 and the post-enhancement T1 relaxation time of MOLLI 4(1)3(1)2, with no significant differences between the combinations. Conclusion: Using phantom-validated sequences, we reported the normal myocardial T1, T2, and ECV reference values of healthy Koreans at 3T. There were no statistically significant differences between the sequences, although it has limited statistical value due to the small number of subjects studied. ECV showed no significant differences between calculations based on various pre- and post-mapping combinations.

CEPHALOMETRIC NORMS OF THE SOFT TISSUES OF KOREAN FOR ORTHOGNATHIC SURGERY (악교정 수술을 위한 한국 성인 정상교합자의 연조직 기준치)

  • Kim, Kyung-Ho;Choy, Kwang-Chul;Kim, Gin-Kap;Park, Kwang-Ho
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.27 no.3
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    • pp.231-238
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    • 2001
  • This study was performed to evaluate soft tissue cephalometric norms for Korean adults which can be implemented in surgical orthodontic treatment planning using selected horizontal reference plane especially for Koreans (Male: $SN-7.5^{\circ}$, Female: $SN-9.0^{\circ}$) and a simplified analytical method. 70 males and 70 females consisting of freshmen of Yonsei University from 1996 to 1997 and students from the Dental College of Yonsei University were chosen according to clinical examination and cephalometric analysis. The samples had normal profiles, normal anteroposterior skeletal relationship(ANB angle of $0^{\circ}\;to\;4^{\circ}$ and Wits appraisal of -4.0mm to 0mm), and Class I molar and canine relationship. They had no missing or supernumerary teeth and had no experience of orthodontic or prosthetic treatment. After the selection of 15 soft tissue landmarks and the construction of horizontal and vertical reference lines, 25 measurements were taken. These consisted of vertical and horizontal linear measurements and angular measurements. The results were as follows. 1. Mean and standard deviation of the measurements were calculated in males and females. 2. Vertical measurements were comparably bigger in males than females whereas anterior facial height ratio(sN-Sn/Sn-sMe) and lower anterior facial height ratio(Sn-Stms/Stmi-sMe) showed no significant difference between sexes. 3. Most of the horizontal measurements in relation to the vertical reference line(G-perpendicular) showed no significant difference between sexes. 4. Nasofacial angle, columellar angle, nasolabial angle and facial contour angle showed no significant difference between sexes. 5. The upper and lower lip were positioned about $-1.0{\pm}2.0mm$ and $+1.0{\pm}2.0mm$ in relation to the Ricketts' esthetic line in both sexes. In this study, soft tissue cephalometric norms of Korean adults for orthognathic surgery were obtained.

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A Controller Design of a Magnetic Levitation System (자기부상 시스템의 제어기 설계)

  • Ha, Y.W.
    • Journal of Power System Engineering
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    • v.4 no.3
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    • pp.62-71
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    • 2000
  • A mathematical modeling for a magnetic levitation system is proposed using the Taylor series expansion of differential function for obtaining linearity. It is confirmed that this kind of linear approximation method can be used to the modeling of a magnetic levitation system. The two-degree-of-freedom optimal servo system for a constant reference signal is proposed using the LQ optimization technique. An additional state feedback is introduced at the output of the integrator to cancel the integral action for reference signal if there is no modeling error of the plant and no disturbance input to the plant. When the modeling error or the disturbance input exists, the integral effect appears. The system has a free parameter which can b used to tune the effect of the integral compensation.

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No-reference PSNR estimation of H.264/AVC video (H.264/AVC 영상의 무참조 PSNR 추정기법)

  • Ryu, Ji-Woo;Lee, Seon-Oh;Sim, Dong-Gyu
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2010.07a
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    • pp.276-277
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    • 2010
  • 비디오 전송시스템에서 사용자가 시청하는 비디오의 화질을 측정하는 것은 중요한 작업이다. 압축된 비디오 스트림에서는 원본 영상이 없어 PSNR을 구할 수 없기 때문에 비디오 스트림 내 정보의 통계적 특성을 이용한 무참조(no-reference) PSNR 추정기법이 사용된다. 그러나 이 알고리즘은 인터 프레임에서의 성능이 매우 떨어지는 단점이 있기 때문에 신뢰도가 떨어지며 ML방법을 이용해 이 문제를 개선한 알고리즘이 있지만 복잡도가 증가하여 상용화에는 부적합하다. 본 논문에서는 이전 프레임의 PSNR과 인터 블록의 통계적 특성을 고려한 새로운 알고리즘을 제안하여 복잡도의 증가 없이 인터 프레임에서의 PSNR 추정 성능을 향상시켰다.

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A Study on No-reference Video Quality Assessment of High Definition Television (HDTV 영상의 원본비참조 화질평가 방법에 관한 연구)

  • Kim, Min-Gi;Park, Dea-Woo
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2011.05a
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    • pp.410-413
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    • 2011
  • 2012년 12월 31일을 기점으로 지상파 아날로그 방송이 종료되고 디지털 방송으로 전환되게 되어, 아날로그 방송에서는 크게 느껴지지 못했던, HDTV 영상 화질에 대한 문제가 대두되고 있다. 방송에서 쓰이는 영상의 경우 대부분 원본은 Tape형식이고, 이를 디지털방송에 맞는 형식으로 압축하여 인코딩한 이후 방송에 적합한 형태로 가공하여 서비스하게 되는데, 이때 MPEG압축 방식에 의해 발생하는 블로킹과 같은 새로운 증상에 대한 문제점이 나타나게 된다. 본 논문에서는, HDTV 영상 화질에서의 일반적으로 인간의 시각이 민감하게 반응하는 블록형 잡음에 대하여, 원본비참조 방법으로, 블록들에 대한 객관적인 점수화 방법에 대하여 연구한다. 본 연구를 통해 HDTV의 고품질화와 정보통신 영상 발전에 기여 할 것이다.

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