• Toxicological Research
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• v.27 no.3
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• pp.133-135
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• 2011

The FDA guidance focuses on the use of the NOAEL to establish the maximum recommended starting dose. The majority of NOAEL has been described inaccurately or incompletely in final reports for 90-days repeated dose toxicity test based on GLP (good laboratory practice) regulation. This is the most serious one of reasons for why most pharmaceutical companies targeting global markets have disregarded the final report produced from GLP facilities in Korea. The problems in deciding NOAEL reflected in the final reports are mainly due to the followings; 1) Inaccurate description or use of NOEL, NOAEL and LOAEL, 2) Insufficient and inappropriate interpretations in findings from toxicity test. This paper is intended to provide the insight into distinguishing NOAEL from NOEL and LOAEL, and into classifying findings from toxicity test. Here, the three step method is newly suggested by applying the weight-based classification to the NOEL, NOAEL and LOAEL based on the findings.

• Economic and Environmental Geology
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• v.17 no.4
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• pp.315-320
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• 1984

The newly discovered minerals found during 30 years have been discovered with election microprobe analysis, and several other new minerals have been described largely on the basis of probe analysis. Widely used types of instrument are the wavelength dispersive spectrometer (WDS) and the energy dispersive Spectrometer (EDS), with emitted X-ray dispersed by a curved crystal that is arranged to satisfy the Bragg equation ($n{\lambda}=2dsin{\theta}$). Atomic Nos of Z 4 to 92 can be analyzed quantitatively if they present in amount exceeding 50~100ppm. The application of the microprobe in mineralogical and geological research is quantitative chemical analysis of grains as small as a few microns in diameter, individual grains in a rock or can be analyzed in thin section and polished section, analysis can be made comparatively short time, methods in non-destructure, to photographical and crystallographical information. This paper was written in order to document data evaluation procedure for quantitative energy dispersive election probe analysis.

• Korean Journal of Environmental Biology
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• v.37 no.3
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• pp.362-366
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• 2019

A marine green algal species (Chlorophyta) was collected from the eastern coast of Korea. It is morphologically characterized by monostromatic thallus, usually undulate and entire margins, cap-like chloroplast and several pyrenoids per cell. In a phylogenetic tree based on molecular data, the Korean alga nests in the same clade as Monostroma alittorale originally described from Japan, as a sister clade of M. grevillei from France. The genetic distance for ITS(Internal Transcribed Spacer) sequences among Monostroma species ranges from 2.3% to 38.2%. The value between the Korean entity and M. alittorale was calculated as 0.01%, considered to be intraspecific divergence. This Korean entity is identified as Monostroma alittorale based on morphological and molecular analyses. This is the first record of M. alittorale in Korea.

• Proceedings of the KOSOMBE Conference
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• v.1994 no.12
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• pp.26-27
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• 1994

The first step implementation of a hospital-wide Picture Archiving Communications System (PACS) at a newly built hospital Samsung Medical Center (SMC), is described. Current clinical operation encompasses the fiber optics delivery of direct-interfaced magnetic resonance imager (LRI), X-ray computed tomography (CT). digital subtraction angiography (DSA) and computed radiography (CR) digital images via high performance file server to the departments of radiology, neurosurgery, orthopedics surgery, neurology, emergency room and the surgical intensive care unit.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.30 no.1
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• pp.148-151
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• 1997

A cossurid polychaete, Cossura brunnea Fauchald, 1972, was newly recorded in Korean fauna. Family Cossuridae is firstly known to in Korean coastal waters. The specimens of the species were collected in the muddy sand bottom. The species was described and illustrated. The key to family was provided.

• 한국연소학회:학술대회논문집
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• 2012.11a
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• pp.167-170
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• 2012

Self-excitations of edge flame were studied in laminar lifted free- and coflow-jet as well as counterflow flames diluted with nitrogen and helium. The self-excitations, originated from variation of edge flame speed and found in the above-mentioned configurations, are discussed. A newly found self-excitation and flame blowout, caused by the conductive heat loss from premixed wings to trailing diffusion flame are described and characterized in laminar lifted jet flames. Some trials to distinguish Lewis-number-induced self-excitation from buoyancy-driven one with O(1.0 Hz) are introduced, and then the differences are discussed. In counterflow configuration, important role of the outermost edge flame in flame extinction is also suggested and discussed.

• Proceedings of the KOSOMBE Conference
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• v.1990 no.11
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• pp.48-51
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• 1990

A new in vivo high resolution imaging method which is performed with a newly developed three channel surface gradient coil (SGC) is described. The surface gradient coil can produce more than an order of magnitude stronger gradient fields with good linearity within a limited imaging region. To increase the signal to noise ratio (SNR), we have developed an RF coil integrated surface gradient coil set. In this paper, the geometrical structures and characteristics of the proposed surface gradient coil are discussed and experimentally obtained high resolution images ($50\;{\mu}m$ to $100\;{\mu}m$) of a water filled phantom and a human volunteer's knee using the new surface RF coil integrated SGC set are presented for the demonstration of the in vivo high resolution imaging capability of the new imaging method.

• Proceedings of the KIEE Conference
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• 2005.07d
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• pp.2477-2479
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• 2005

A robust bending frequency tracker is proposed to design the adaptive notch filter which removes the time-varying missile structural modes from the sensor measurements. To do this, the state-space form of a bending frequency model is derived under the assumption that the bending signal could be described as the lightly damped sinusoid. Since the resultant bending frequency model contains the parametric uncertainties in the measurement matrix, the design problem of bending frequency tracker is tackled by applying the robust Kalman filter to the model. This technique could be easily expanded to the multiple frequencies case because it newly illuminates the bending frequency tracking problem in view of general state estimation.

• Korean Journal of Bronchoesophagology
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• v.16 no.1
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• pp.20-26
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• 2010

Transoral $CO_2$ Laser Microsurgery of glottic Carcinoma is replacing external approaches. The qualify of life after surgery for laryngeal cancer may be as important as complete resection of the tumor for patient. Transoral $CO_2$ laser cordectomy for the management of early laryngeal cancer has advantages with regard to oncological results, preservation of laryngeal functions, morbidity and cost in comparison to those of open surgery or radiation therapy. Moreover, transoral laser surgery can be a useful choice as a salvage surgery in radiation therapy failed early glottic cancer. A classification of laryngeal endoscopic cordectomies which included eight different types was described by the European laryngological Society in 2000. We will also introduce type VI which was newly proposed recently.

• Proceedings of the KWS Conference
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• 2002.10a
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• pp.732-736
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• 2002

The introduction of newly developed intelligent and user-friendly robotics has opened a new era in shipbuilding. Together with traditional and low-cost mechanization a record level of welding automation rate has been achieved in the construction of cruise vessels. In the paper modem applications and recent developments of welding automation and robotics in shipbuilding have been described and some forecast for the future trends are given. Development in the field of shipyards will be continued with accelerated speed and we shall have interesting prospects for the near future. New laser techniques can boost the shipyards in a revolutional way when production is rapidly changing, materials will be lighter and quality demands are becoming more strict.