• 제목/요약/키워드: new discovery

검색결과 904건 처리시간 0.027초

An On Demand Routing Algorithm for Mobile Wireless Networks

  • Yan, Huai-Zhi;Ajith, P.K.;Park, Dong-Won;Joo, Gi-Ho
    • 공학논문집
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    • 제7권1호
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    • pp.37-51
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    • 2005
  • An and hoc network is a collection of wireless mobile nodes forming a temporary network without the centralized administration. Due to the limited transmission range of wireless work interface, multiple networks "hops" maybe needed for one node to exchange data with adjacent node. In recent years, a variety of new routing protocol about ad hoc network was developed. This paper presents a new routing protocol based on the Dynamic Source Routing which is not suitable for the high mobility ad hoc network. The Enhanced DR adapts quickly to routing changes when node movement is frequent. When a trunk route is broken, this protocol will utilize the alternative route saved in the route to discovery quickly the new route. It improves the performance of the existing DSR algorithm, so that the negative impacts from weakness of DSR are reduced.

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The New Way to Define Key Oncogenic Drivers of Small Cell Lung Cancer

  • Kee-Beom Kim
    • 한국발생생물학회지:발생과생식
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    • 제27권1호
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    • pp.1-7
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    • 2023
  • Small-cell lung cancer (SCLC) continues to be the deadliest of all lung cancer types. Its high mortality is largely attributed to the unchangeable development of resistance to standard chemo/radiotherapies, which have remained invariable for the past 30 years, underlining the need for new therapeutic approaches. Recent studies of SCLC genome revealed a large number of somatic alterations and identified remarkable heterogeneity of the frequent mutations except for the loss of both RB and P53 tumor suppressor genes (TSGs). Identifying the somatic alterations scattered throughout the SCLC genome will help to define the underlying mechanism of the disease and pave the way for the discovery of therapeutic vulnerabilities associated with genomic alterations. The new technique made it possible to determine the underlying mechanism for the discovery of therapeutic targets. To these ends, the techniques have been focused on understanding the molecular determinants of SCLC.

NSIS 프로토콜을 이용한 사전자원예약 방안 (A Pre-Resource Reservation Mechanism using NSIS protocol)

  • 김선영;변해선;이미정
    • 한국정보과학회논문지:정보통신
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    • 제35권6호
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    • pp.538-548
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    • 2008
  • IETF(Internet Engineering Task Force) NSIS(Next Step in Signaling) 워킹그룹에서는 MN(Mobile Node)의 핸드오버로 인해 데이타 전달 경로가 변경된 경우, 이전 경로와 새로운 경로가 분기 또는 통합되는 지점에 있는 노드인 CRN(Crossover Node)을 발견하는 방안을 제안하였다. 이 방안에서는 CRN 발견을 통해 새로운 경로 상에 자원예약 시그널링 지연을 줄이고 이전 경로와 새로운 경로의 공통경로 상에 중복 자원예약을 피함으로써 핸드오버 이후의 자원예약을 효율적으로 수행한다. 그러나 MN이 핸드오버하는 동안 지속적으로 QoS(Quality of Service)를 보장받기 위해서는 핸드오버 이전에 새로운 경로 상의 사전자원예약이 이루어져야 한다. 그런데 아직 핸드오버하지 않은 MN이 새로운 경로 상에 사전자원예약을 수행하려는 경우에는 기존의 CRN 메커니즘을 적용하기 어렵다. 이에 본 논문에서는 현재 자인이 예약된 경로와 MN이 핸드오버 할 가능성이 있는 하나 이상의 지역의 새로운 경로 상에 CRN이 될 가능성이 있는 노드인 PCRN(Passive Crossover Node)을 발견하고, 이후 새로운 경로 상에 사전자원예약을 수행하는 방안을 제안한다.

From The Discovery Challenge on Thrombosis Data

  • Takabayashi, Katsuhiko;Tsumoto, Shusaku
    • 한국지능정보시스템학회:학술대회논문집
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    • 한국지능정보시스템학회 2001년도 The Pacific Aisan Confrence On Intelligent Systems 2001
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    • pp.361-363
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    • 2001
  • Although data mining promises a new paradigm to discover medical knowledge form a database, there are many problems to be solved before real application is feasible. We had the chance to provide a data set to be analyzed as a discovery challenge by using various data mining techniques at the PKDD conference. As data providers, we evaluated and discussed results and clarified problems.

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A Perspective on Pharmaceutical Industrial Research on Antihypertensive drugs

  • Lee, Jang-Yun;John F. DeBernardis
    • Archives of Pharmacal Research
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    • 제10권4호
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    • pp.245-249
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    • 1987
  • Cardiovascular disease is at present the leading cause of deth in the United States and other in dustrilized countries. A major contributing factor of cardiovascular disease is essential hypertension. Untreated, essential hypertension is considered a risk factor for sudden death due to myocardial infarctions, as well as a risk factor for cerebral vascular disease, renal failure and congestive heart failure. During the last decade, significant progress has been made in the basic knowledge of the pathogenesis of hypertension as well as in the development of new antihypertensive drugs.

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Plant Anticancer Agents and Cancer Chemopreventives: Recent Progress

  • Kinghorn, A.Douglas
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-1
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    • pp.58-59
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    • 2003
  • There is considerable interest in the screening of higher plant extracts in modem drug discovery programs to discover new chemotypes with potent and selective biological activity. Such work may be performed in different laboratory settings, including those in academic institutions. In the case of cancer, plants offer the potential for the discovery of both cancer chemotherapeutic agents and cancer chemopreventives. (omitted)

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