• Title/Summary/Keyword: negative pressure

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Validity of Self-reported Hypertension and Factors Related to Discordance Between Self-reported and Objectively Measured Hypertension: Evidence From a Cohort Study in Iran

  • Najafi, Farid;Pasdar, Yahya;Shakiba, Ebrahim;Hamzeh, Behrooz;Darbandi, Mitra;Moradinazar, Mehdi;Navabi, Jafar;Anvari, Bita;Saidi, Mohammad Reza;Bazargan-Hejazi, Shahrzad
    • Journal of Preventive Medicine and Public Health
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    • v.52 no.2
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    • pp.131-139
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    • 2019
  • Objectives: Self-reporting can be used to determine the incidence and prevalence of hypertension (HTN). The present study was conducted to determine the validity of self-reported HTN and to identify factors affecting discordance between self-reported and objectively measured HTN in participants in the Ravansar Non-Communicable Diseases (RaNCD) cohort. Methods: The RaNCD cohort included permanent residents of Ravansar, Iran aged 35-65 years. Self-reported data were collected before clinical examinations were conducted by well-trained staff members. The gold standard for HTN was anti-hypertensive medication use and blood pressure measurements. The sensitivity, specificity, positive and negative predictive values, and overall accuracy of self-reporting were calculated. Univariate and multivariate logistic regression were used to examine the discordance between self-reported HTN and the gold standard. Results: Of the 10 065 participants in the RaNCD, 4755 (47.4%) were male. The prevalence of HTN was 16.8% based on self-reporting and 15.7% based on medical history and HTN measurements. Of the participants with HTN, 297 (18.8%) had no knowledge of their disease, and 313 (19.9%) had not properly controlled their HTN despite receiving treatment. The sensitivity, specificity, and kappa for self-reported HTN were 75.5%, 96.4%, and 73.4%, respectively. False positives became more likely with age, body mass index (BMI), low socioeconomic status, and female sex, whereas false negatives became more likely with age, BMI, high socioeconomic status, smoking, and urban residency. Conclusions: The sensitivity and specificity of self-reported HTN were acceptable, suggesting that this method can be used for public health initiatives in the absence of countrywide HTN control and detection programs.

A Management Plan of the Resources for Emergency Medical Facility at Disaster Site (재난현장 응급의료 시설자원 관리방안)

  • Song, Youngsub;Suh, Sangwook;Yoon, Yousang
    • Korean Journal of Construction Engineering and Management
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    • v.20 no.3
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    • pp.46-53
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    • 2019
  • Recently, the need for emergency medical facilities is increasing due to a large-scale disaster. The Ministry of the Interior and Safety has completed the development of Disaster Resource Sharing System (DRSS). In this system, only air tent and negative pressure tent, which are classified and managed as equipment are resources related to emergency medical facility at disaster site. However, the characteristics of resources for the facility such as the time of input, a period of stay, transportation, and installation methods were not reflected. So, The purpose of this study is to propose improvements of management of resources for emergency medical facility at disaster site, that classified to materials and equipment in DRSS. This study analyzed the state of resources for facilities and the attributes of resources based on literature and disaster medical consultation of mobile hospitals. The resources for emergency medical facility are required to be linked to medical support resources and reflected in the DRSS, since emergency medical facility resources at the disaster site should be managed through a combination of medical resources classified as equipment. And future research on installation of emergency medical facilities plan considering the cost of the disaster management resources should be carried out.

Telmisartan increases hepatic glucose production via protein kinase C ζ-dependent insulin receptor substrate-1 phosphorylation in HepG2 cells and mouse liver

  • Cho, Kae Won;Cho, Du-Hyong
    • Journal of Yeungnam Medical Science
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    • v.36 no.1
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    • pp.26-35
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    • 2019
  • Background: Dysregulation of hepatic glucose production (HGP) contributes to the development of type 2 diabetes mellitus. Telmisartan, an angiotensin II type 1 receptor blocker (ARB), has various ancillary effects in addition to common blood pressure-lowering effects. The effects and mechanism of telmisartan on HGP have not been fully elucidated and, therefore, we investigated these phenomena in hyperglycemic HepG2 cells and high-fat diet (HFD)-fed mice. Methods: Glucose production and glucose uptake were measured in HepG2 cells. Expression levels of phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-phosphatase ${\alpha}$ ($G6Pase-{\alpha}$), and phosphorylation levels of insulin receptor substrate-1 (IRS-1) and protein kinase C ${\zeta}$ ($PKC{\zeta}$) were assessed by western blot analysis. Animal studies were performed using HFD-fed mice. Results: Telmisartan dose-dependently increased HGP, and PEPCK expression was minimally increased at a $40{\mu}M$ concentration without a change in $G6Pase-{\alpha}$ expression. In contrast, telmisartan increased phosphorylation of IRS-1 at Ser302 ($p-IRS-1-Ser^{302}$) and decreased $p-IRS-1-Tyr^{632}$ dose-dependently. Telmisartan dose-dependently increased $p-PKC{\zeta}-Thr^{410}$ which is known to reduce insulin action by inducing IRS-1 serine phosphorylation. Ectopic expression of dominant-negative $PKC{\zeta}$ significantly attenuated telmisartan-induced HGP and $p-IRS-1-Ser^{302}$ and -inhibited $p-IRS-1-Tyr^{632}$. Among ARBs, including losartan and fimasartan, only telmisartan changed IRS-1 phosphorylation and pretreatment with GW9662, a specific and irreversible peroxisome proliferator-activated receptor ${\gamma}$ ($PPAR{\gamma}$) antagonist, did not alter this effect. Finally, in the livers from HFD-fed mice, telmisartan increased $p-IRS-1-Ser^{302}$ and decreased $p-IRS-1-Tyr^{632}$, which was accompanied by an increase in $p-PKC{\zeta}-Thr^{410}$. Conclusion: These results suggest that telmisartan increases HGP by inducing $p-PKC{\zeta}-Thr^{410}$ that increases $p-IRS-1-Ser^{302}$ and decreases $p-IRS-1-Tyr^{632}$ in a $PPAR{\gamma}$-independent manner

The Analysis of fragmentation on the Jirisan National Park for the Improvement of Asiatic Black Bear's habitat environment (반달가슴곰 서식환경 개선을 위한 지리산 국립공원 파편화 분석)

  • Bae, Je-Sun;Oh, Choong-Hyeon
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.24 no.1
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    • pp.1-14
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    • 2021
  • The Ministry of Environment of Korea has been releasing Asiatic black bears since 2004 at Jirisan National Park. It exceeded the target number of Asiatic black bears in 2018. As of July 2020, in addition to 67 traceable bears, many Asiatic black bears are dispersed outside Jirisan National Park. Jirisan National Park is a very dense place with more than 3 million visitors every year. In this study, the roads and trails through Jirisan National Park were considered to be the main dispersion factors of Asiatic black bears, and the fragmentation analysis was conducted. As of July 2017, the length of roads and trails in Jirisan National Park was 363.4km. Based on this, Jirisan National Park was fragmented into 163 patches. There is only one place that maintains a single area of more than 50㎢ that is suitable for large mammals to inhabit, and 141 places are less than 5㎢. There are 6 patches of 24 to 200㎢ area suitable for living of large mammals including Asiatic black bears, in Jirisan National Park. Compared to the announcement made by the Korea National Park Service in 2014, activities of Asiatic black bears were rare in areas below 5㎢ area and the frequency of activities was high in more than 20㎢ area. This shows that human activities in protected areas such as national parks can directly affect the activities of wild animals, including Asiatic black bears. Therefore, efforts should be made to improve the habitat of Asiatic black bears by reducing the pressure of visiting for Jirisan National Park. In addition, as a result of analyzing the fragmentation of the park's natural conservation zone 107.7km, 45% of the trail of Jirisan National Park, was opened, which is more fragmentation than other use zones. The park nature conservation zone accounts for about 32% of the total area of Jirisan National Park, but the average patch area is only 2.93㎢ and seven large shelters are located. Therefore the Asiatic black bears are negatively affected. This is the result of inconsistent national park use zone setting and actual park management. In overseas countries, research is active on the negative effects of human activity on ecosystems in protected areas. However, there is a lack of research of that in Korea. Thus, that research is required for protection area management in the future.

A Numerical Study on Ventilation Characteristics of Factors Affecting Leakages in Hydrogen Ventilation (누출 수소 환기에 영향을 미치는 요인별 환기 특성에 관한 수치해석적 연구)

  • Lee, Chang-Yong;Cho, Dae-Hwan
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.28 no.4
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    • pp.610-619
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    • 2022
  • Hydrogen is emerging as an alternative fuel for eco-friendly ships because it reacts with oxygen to produce electrical energy and only water as a by-product. However, unlike regular fossil fuels, hydrogen has a material with a high risk of explosion due to its low ignition point and high flammability range. In order to safely use hydrogen in ships, it is an essential task to study the flow characteristics of hydrogen leakage and diffusion need to be studied. In this study, a numerical analysis was performed on the effect of leakage, ventilation, etc. on ventilation performance when hydrogen leaks in an enclosed space such as inside a ship. ANSYS CFX ver 18.1, a commercial CFD software, was used for numerical analysis. The leakage rate was changed to 1 q, 2 q, and 3 q at 1 q = 1 g/s, the ventilation rate was changed to 1 Q, 2 Q and 3 Q at 1 Q = 0.91 m/s, and the ventilation method was changed to type I, type II, type III to analyze the ventilation performance was analyzed. As the amount of leakage increased from 1 q to 3 q, the HMF in the storage room was about 2.4 to 3.0 times higher. Furthermore, the amount of ventilation to reduce the risk of explosion should be at least 2 Q, and it was established that type III was the most suitable method for the formation of negative pressure inside the hydrogen tank storage room.

Appropriate Technology, Responding to the COVID-19 Pandemic - Redefined Roles in a Public Health Crisis (Part II) (COVID-19 대유행에 대응하는 적정기술 : 보건 위기에서 재정의된 역할 - 파트 2)

  • Pyun, Nayoon;Lee, Sungwoo;Suh, Jungwoo;Kim, Jaeeun;Jang, Dongyoon;Shin, Kwanwoo
    • Journal of Appropriate Technology
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    • v.6 no.2
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    • pp.256-270
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    • 2020
  • The collapse of the medical and healthcare system in the pandemic is resulting in the voluntary participation of civil society and a new way of responding. Some of new countermeasure can be immediately utilized at the forefront of the health crisis. Appropriate technology is no longer an intermediate technology, demonstrating its role as a technology capable of overcoming the crisis of not only developing countries but also any countries where the health system has collapsed. In this Part 2, examples of health fields such medical devices as negative pressure chambers and ventilators, diagnostic chips, and diagnostic techniques, are being discussed as a quick response to the collapse of health systems under COVID-19, within the framework of appropriate technologies. Finally, the important role of scientists and engineers is discussed for the prevention of severe impacts on the vulnerable people in terms of socioeconomic status.

The Effect of the Job Satisfaction, the Employment Barriers and the Risk-taking Orientation on the Entrepreneurial Intention of Undergraduates Majoring in Cultural and Arts (문화예술전공 대학생의 직무만족, 고용장벽, 위험감수성향이 창업의도에 미치는 영향)

  • Jeong, Jae-Yeob
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.8
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    • pp.11-23
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    • 2020
  • Many former studies for the entrepreneurial intention dealt with the opportunity-driven motivation, but the actual entrepreneurial motivation is the necessity-driven motivation such as maintaining a living. It is necessary to study the necessity-driven factors for entrepreneurship such as employment barriers and job dissatisfaction. This study focused on the fact that the majority of cultural artists are freelancers or self-employed entrepreneurs. For those who majored in culture and arts, this study was conducted to investigate how an individual's internal and external environment affects the entrepreneurial intention considering the theory of planned behavior. I explored the factors that led individuals to choose entrepreneurial intention between employment and entrepreneurship, and studied the relationship between these factors and the entrepreneurial intention. As the result of the study, the job dissatisfaction and the employment barriers were the pressure factors for entrepreneurship. Job satisfaction had a negative effect on the entrepreneurial outcome expectation and the entrepreneurial intention. The perceived employment barrier had a positive effect on the entrepreneurial outcome expectation and the entrepreneurial intention. An individual's risk-taking orientation is one of the entrepreneurship and had the positive effect on the entrepreneurial self-efficacy. The entrepreneurial outcome expectation and the entrepreneurial self-efficacy had a positive effect on the entrepreneurial intention.

A Qualitative Study on the Busyness and Subjective Pace of Life among Koreans in Early Adulthood (성인초기 한국인의 바쁨과 주관적인 삶의 속도에 대한 질적 연구)

  • Woo, Ami;Jung, Taeyun
    • Korean Journal of Culture and Social Issue
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    • v.27 no.4
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    • pp.529-559
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    • 2021
  • This study examines how people perceive and experience busyness, which is a great social pressure in the Korean society, and The socio-psychological motives that drive people's different paces of life, such as busyness or slowness, despite being in the same busy reality, were examined. Furthermore, an in-depth study was conducted on the adaptation factors in the real society according to the speed of individual life. The analysis of this study was based on an in-depth interview data of 21 unmarried men and women in their 20s and 30s, and was conducted using a phenomenological qualitative analysis method. As a result, the perception and experience of being busy had both positive and negative parts. The components of socio-psychological motivation that affect the speed of an individual's life are 'internalization of positive values of (busy/rest)', '(future/present) centric', 'selection & concentration/Inertial busyness', 'personality characteristics' were derived. In addition, 'self-selection', 'successful time management', and 'maintenance of psychological health' were derived as common factors among adaptation factors in real society, 'a sense of achievement' and 'understanding and accepting self-characteristics' were derived as discriminatory factors. became Based on these results, the value and meaning of being busy in Korean society was discussed from a social psychology perspective, and a new perspective was presented to existing studies and discussions related to the speed of life. In addition, several follow-up studies were proposed.

The Relationship between Enterance Exam Stress and Oral Care Self-Efficacy in 3rd year Girl High School Students (인문계 3학년 여자 고등학생의 입시스트레스와 구강관리 자기효능감과의 관련성)

  • Cho, Hye-Eun;Chung, Kyung-Yi
    • Journal of Korea Entertainment Industry Association
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    • v.13 no.8
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    • pp.551-561
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    • 2019
  • The purpose of this study was to investigate the relationship between entrance exam stress and oral care self-efficacy in girls high school. From June to July 2018, A self-reported questionnaire was administered to 192 high school students in the G area. The data were analyzed for independent t-test, one-way ANOVA and Pearson's correlation coefficient by using SPSS/WIN 21.0 program. Among the sub-sectors of entrance exam stress, exam tension/poor was the highest with 3.07 points, followed by Insufficient spare time stress 2.83 points, future uncertainty stress 2.57 points, and parent pressure stress 2.44 points. the variables related to exam tension/poor stress were academic performance (p<.01), family income level (p<.05), Subjective oral health status(p<.05), and daily brushing frequency(p<.01). The highest level of oral care self-efficacy was 3.13 points for brushing self-efficacy, followed by dental visits 2.80 points and interdental hygiene 2.64 points. As a result of analyzing the general characteristics and oral care self-efficacy, subjects related to brushing self-efficacy were subjective oral health status, caries snacking(daily), and caries drinks(daily)(p<.01). There were negative correlations between entrance exam stress and oral care self-efficacy. The higher the entrance stress, the lower the oral care self-efficacy. To prevent oral disease and increase oral care self-efficacy of students with high entrance stress, it is necessary to provide school oral health education programs that can facilitate oral health behaviors.

The Impact of US Monetary Policy upon Korea's Financial Markets and Capital Flows: Based on TVP-VAR Analysis (미국 통화정책이 국내 금융시장 및 자금유출입에 미치는 영향: TVP-VAR 모형 분석)

  • Suh, Hyunduk;Kang, Tae Soo
    • Economic Analysis
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    • v.25 no.2
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    • pp.132-176
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    • 2019
  • We use a time-varying parameter vector auto regression (TVP-VAR) model to understand the impact of U.S. monetary policy normalization on Korean financial markets and capital accounts. The U.S. monetary policy is represented by the federal funds rate, term premium and credit spread. During the U.S. monetary contraction period of 2004 to 2006, changes in the federal funds rate presented negative pressure on Korean financial markets. The changes in federal funds rate also led to a simultaneous contraction in inward and outward capital flows. However, the effects of a federal funds rate shock has been reduced since 2015. On the other hand, the effects of U.S. term premiums is getting stronger after the period of quantitative easing (QE). The influence of the U.S. credit spread also significantly increased after the global financial crisis. Simulation results show that a rise in the U.S. credit spread, which can be triggered by a contractionary monetary policy, can pose a larger adverse impact on the Korean economy than a rise in the federal funds rate itself. As for capital flows, a U.S. monetary policy contraction causes an outflow of foreign investment, but the repatriation of overseas investment by Korean residents can offset this outflow.