• 제목/요약/키워드: negative number and function

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The Impact of COVID-19 on Individual Industry Sectors: Evidence from Vietnam Stock Exchange

  • TU, Thi Hoang Lan;HOANG, Tri M.
    • The Journal of Asian Finance, Economics and Business
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    • 제8권7호
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    • pp.91-101
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    • 2021
  • The paper examines the impact of the COVID-19 pandemic on the stock market prices. The vector autoregression model (VAR) has been used in this analysis to survey 341 stocks on the Ho Chi Minh City Stock Exchange (HOSE) for the period from January 23, 2020 to December 31, 2020. The empirical results obtained from the analysis of 11 economic sectors suggest that there is a statistically significant impact relationship between COVID-19 and the healthcare and utility industries. Additional findings show a statistically significant negative impact of COVID-19 on the utility share price at lag 1. Analysis of impulse response function (IRF) and forecast error variance decomposition (FEVD) show an inverse reaction of utility stock prices to the impact of COVID-19 and a gradual disappearing shock after two steps. Major findings show that there is a clear negative effect of the COVID-19 pandemic on share prices, and the daily increase in the number of confirmed cases, indicate that, in future disease outbreaks, early containment measures and positive responses are necessary conditions for governments and nations to protect stock markets from excessive depreciation. Utility stocks are among the most severely impacted shares on financial exchanges during a pandemic due to the high risk of immediate or irreversible closure of manufacturing lines and poor demand for basic amenities.

Immunoregulatory Function of HLA-G in Gastric Cancer

  • Tuncel, Tolga;Karagoz, Bulent;Haholu, Aptullah;Ozgun, Alpaslan;Emirzeoglu, Levent;Bilgi, Oguz;Kandemir, Emin Gokhan
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권12호
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    • pp.7681-7684
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    • 2013
  • Background: Human leukocyte antigen (HLA)-G-positive gastric cancers are associated with poor survival, but links with tumor escape mechanisms remain to be determined. Materials and Methods: We used immunohistochemistry to investigate HLA-G expression, tumor infiltrating CD8+ T lymphocytes, and Treg cells in 52 gastric cancer patients. Results: There were 29 cancer-related deaths during the follow-up period. Kaplan-Meier analysis indicated that patients with HLA-G-positive (n=16) primary tumors had a significantly poorer prognosis than patients with HLA-G-negative tumors (n=36, p=0.008). The median survival time was 14 months and 47 months, respectively. Patients with high numbers of Tregs and low numbers of CD8+T lymphocytes in the primary tumor had a poorer prognosis than those with low numbers of Tregs and high numbers of CD8+T lymphocytes (p=0.034, p=0.043). Multivariate Cox proportional hazard regression analysis showed that HLA-G expression (hazard ratio: 2.662; 95% confidence interval: 1.242-5.723; p=0.012) and stage (hazard ratio: 2.012;95% confidence interval: 1.112-3.715; p=0.041) were independent unfavorable factors for patient survival. Conclusions: We found a significant positive correlation between HLA-G expression and the number of tumor infiltrating Tregs (p=0.01) and a negative correlation with the number of CD8+T lymphocytes (p=0.041). HLA-G may protect gastric cancer cells from cytolysis by inducing Foxp3+Treg lymphocytes and suppressing CD8+T lymphocytes.

위그너-빌 분포함수에서의 혼신성분 저감 방법 - 회전 창문함수 (A Method to Reduce the Cross-Talk of Wigner-Ville Distribution;Rotating Window)

  • 박연규;김양한
    • 소음진동
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    • 제7권2호
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    • pp.319-329
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    • 1997
  • Wigner-Ville distribution has been recognized as a useful tool and applied to various types of mechanical noise and vibration signals, but its limitation which mainly comes from the cross-talk has not been well addressed. The cross-talk takes place for a signal with multiple components, simply because the Wigner-Ville distribution is a bilinear transform. The cross-talk often causes a negative value in the distribution. This cannot be accepted for the Wigner- Ville distribution, because it is an expression of power. Smoothing the Wigner-Ville distribution by convoluting it wih a window, is most commonly used to reduce the cross-talk. There can be infinite number of distributions depending on the windows. In this paper, we attempted to develop a distribution which is the best or the optimal in reducing the cross-talk. This could be possible by employing the ambiguity function. For a general signal, however it is difficult to express the ambiguity function as a mathematically closed form. This requires an appropriate modeling to make such expression possible. We approximated the Wigner-Ville distribution as a sum of linear segments. In the ambiguity function domain, the legitimate components are reflected as linear lines passing through the origin. Every lines has its own length and slope. But, the cross-talk is widely distributed in the ambiguity function plane. Based on this realization, we proposed a two-dimensional window which is in fact 'rotating window', that can eliminate cross-talk component. The rotating window is examined numerically and is found to have a better performance in reducing the cross-talk than conventional windows, the Gaussian window.

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The Suppression Effect of Garcinia Mangostana L. Pericarp Extract on Cerebral Neovascularization in Type 2 Diabetic Mellitus Rats

  • Muhammad Mufaiduddin;Vega Karlowee;Yora Nindita;Muflihatul Muniroh
    • Natural Product Sciences
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    • 제29권2호
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    • pp.91-97
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    • 2023
  • Mangosteen peel extract is a xanthone group, that plays an important role in anti-angiogenesis. This study investigated mangosteen peel extract on cerebral neovascularization in type 2 diabetes mellitus (DM) rats. This study used 36 rats, randomized into six groups: C1 (negative control); C2 (high fat diet (HFD) and mangosteen peel extract at 200 mg/kg BW); C3 (HFD and diabetic); E1, E2, and E3 (HFD, diabetic, and extract at 100, 200, and 400 mg/kg BW respectively). All groups were measured body mass index (BMI), homeostasis model assessment-insulin resistance (HOMA-IR) and β cell function (HOMA-B), and histopathological feature of cerebral vascular (CV). There were significant differences in BMI, HOMA-IR, HOMA-B, and the mean number of CV (all p < 0.05) among treatment groups. E1-3 groups had a significantly lower level of blood glucose and HOMA-IR, and a higher level of HOMA-B and BMI (all p < 0.05) which tends to reduce cerebral neovascularization. HOMA-IR independently had a positive effect to induce neovascularization of CV (p < 0.05, R2 = 26.8%). These findings suggested that mangosteen peel extract increased β-cell function sensitivity, and effectively suppressed insulin resistance, BMI, and cerebral neovascularization process in type 2 DM rats.

Role of Amino Acid Residues within the Disulfide Loop of Thanatin, a Potent Antibiotic Peptide

  • Lee, Myung-Kyu;Cha, Li-Na;Lee, Si-Hyung;Hahm, Kyung-Soo
    • BMB Reports
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    • 제35권3호
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    • pp.291-296
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    • 2002
  • Thanatin, a 21-residue peptide, is an inducible insect peptide with a broad range of activity against bacteria and fungi. It has a C-terminal disulfide loop, like the frog skin secretion antimicrobial peptides of the brevinin family. In this study, we tried to find the effect of a number of amino acids between the disulfide bond. Thanatin showed stronger antibacterial activity to Gram negative bacteria than other mutants, except Th1; whereas, the mutant peptides with deletion had higher activity to Gram positive bacteria than thanatin. An increase in the number of amino acid(s) using the alanine residue decreased the antibacterial activity in all of the bacteria. Th1 with deletion of threonine at position 15 ($Thr^{15}$) showed similar antibacterial activity against Gram-negative bacteria, but had higher activity against the Gram positive bacteria. In order to study the structure-function relationship, we measured liposome disruption by the peptides and CD spectra of the peptides. Th1 also showed the highest liposome leaking activity and α-helical propensity in the sodium dodecyl sulfate solution, compared with other peptides. Liposome disruption activity was closely correlated with the anti-Gram positive bacterial activity. All of the peptides showed no hemolytic activity. Th1 was considered to be useful as an antimicrobial peptide with broad spectrum without toxicity.

위탁 급식 점포의 메뉴 운영 요인과 성과의 연관성에 관한 연구 (A Canonical Correlation Analysis of the Relationship between Menu Management Variables and Performance in Contract-Foodservice Operations)

  • 박주연;김태희
    • 동아시아식생활학회지
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    • 제18권6호
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    • pp.1089-1098
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    • 2008
  • The principal objective of this study was to reveal the relationship between the menu management indicators and menu performance indicators in contract-foodservice operations. Menu indicators differed according to the type of business, type of contract, type of serving, and number of service lines. In accordance with the results of our correlation analysis, we noted significant correlations between menu performance indicators and menu management indicators. The first of these was the correlation between the food cost ration and meal counts, food loss, and the use of prepared vegetables. The second of these was the correlation between food cost per meal and forecasting error, food loss, and inventory turnover. The last of these correlations was the negative correlation between menu CSI(customer satisfaction index) and the use of prepared vegetables. According to the results of our canonical correlation analysis, 2 significant functions were identified. In the first function, we noted significant correlations between meal counts, use of prepared vegetables, food loss, and food cost ratio. Additionally, we noted significant correlations between forecasting error, inventory turnover, food loss, and food cost per meal in the second function. Menu management indicators had no influence on customer satisfaction.

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초등학생 어머니의 성격유형에 따른 양육태도 및 양육스트레스 (A Study on Parenting Attitude and Stress according to Personality Type in Elementary School Students' Mothers)

  • 고효정;권윤희;김민영
    • 지역사회간호학회지
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    • 제20권2호
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    • pp.215-224
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    • 2009
  • Purpose: This study was performed to examine parenting attitude and stress according to personality type in elementary school students' mothers. Methods: The subjects consisted of 206 mothers of students. The measurement instrument was the questionnaire consisting of Korean-version MBTI and PSI test. Data was collected from March 15th to April 15th, 2008. Results: Among personality types by function, ST type was most, occupying 60.2%. Among personality types by temperament, SJ type was most, occupying 59.2%. The score of affective attitude was highest among the parenting attitudes. Parenting attitude was significantly different according to age, education, economic status, number of children, planned pregnancy, factor of stress, and family type. Parenting stress was significantly different according to planned pregnancy and factor of stress. In parenting attitudes by personality types, affective attitude was significantly different. Parenting stress was significantly different according to personality type by function. There was a negative correlation between affective and autonomic attitudes and parenting stress. There was a positive correlation between rejective attitude and parenting stress. Conclusion: It would be essential to provide dynamic developmental programs for increasing the children's social ability, and nursing intervention, education and counseling programs for decreasing parenting stress through understanding mothers' personality type.

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지하공간 설계에 있어서의 심리적 요인에 대한 고찰 (Psychological lssues in the Design of Underground Facilities)

  • 김치환
    • 터널과지하공간
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    • 제4권2호
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    • pp.186-191
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    • 1994
  • In recent decades, underground usage in urban areas has expanded from subways and utilities to include virtually every non-residential building function. Greater usage of underground space is envisioned in the more congested urban areas in the world such as Asia and Europe. This increasing interest in underground development is raising basic questions about whether people can work and live underground, and if so, what design techniques can sucessfully be employed. The actual experience of people in underground space, as well as general associations and image of the underground reveal predominantly negative attitudes. A number of design techniques have been suggested by researchers, or actually utilized by designers, to alleviate these potential problems for people in underground space. This paper identifies these psychological and physiological problems. In addition, design objective and possible solutions are briefly summarized. This is followed by a summary of special design problems and objectives related to road tunnels.

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Comparison of Functional Independence among Community-dwelling Older Adults in Rural Areas in South Korea and the United States

  • Lee, Jia
    • 성인간호학회지
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    • 제24권5호
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    • pp.540-545
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    • 2012
  • Purpose: The purpose of the study was to compare level of functional independence and its correlates among community-dwelling older adults in rural areas between South Korea and the United Sates. Methods: The study employed a comparative and correlational design. Data were collected from 198 community-dwelling older adults in rural areas (South Korea=100, & US = 98). Functional independence, cognitive function, obesity and general characteristics were measured. Results: From both countries, approximately fifteen percent of older adults living independently had cognitive problems without any treatments. Among Korean older adults functional independence was associated with a number of chronic diseases and aging while in the United States the participants had a negative correlation with obesity and aging. Conclusion: For Korean older adults in rural areas, nurses should focus on monitoring older adults' abilities to manage chronic illness and designing self-management programs while in the United States the focus should be on healthy lifestyle programs about exercise and diet to increase functional independence.

A Study on Tourist Psychological Capacity of Scenic and Historic Area and Its Influencing Factors - A Case Study of Mount Tai Scenic Spot

  • Cao, Lin-Sen;Piao, Yong-Ji;Zhang, Rui;Cho, Tae-Dong
    • 한국환경과학회지
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    • 제23권5호
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    • pp.755-761
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    • 2014
  • Tourist Psychological Capacity (TPC) is an important issue of the Tourism Capacity research. We gained the tourist satisfaction through the questionnaire investigation in Mount Tai Scenic Area and obtained the tourist satisfaction function using SPSS17.0 regression analysis method. Then we got the best psychological capacity of tourists with the Marginal Satisfaction Method. Finally we verified the influencing factors on TPC. The study found that the best TPC of Mount Tai Scenic Area is 10323 persons; Female shows lower TPC than male. Moreover, female satisfaction is more easily influenced by visitors' number increasing than male satisfaction; TPC plays negative correlation with the increasing of age. Teenagers and adults have no much difference in TPC, but the seniors present a relatively lower TPC than other; The higher education, the smaller TPC.