• 대한정형외과학회지
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• 제54권6호
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• pp.509-518
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• 2019

목적: 악성 종양 환자에서 림프절 전이를 발견하는 것은 초기에 정확한 병기 및 예후와 관련된 정보를 알 수 있고 수술 후 보조치료(adjuvant therapy)의 필요성을 평가해서 조기에 치료를 할 수 있도록 해주기 때문에 중요하다. 본 연구를 통해 정형외과 영역의 악성 종양 환자를 평가함에 있어 양전자 방출 컴퓨터 단층 촬영기(positron emission tomography/computed tomography, PET/CT)가 sentinel lymph node biopsy와 비교하여 유용한지를 알아보고자 한다. 대상 및 방법: 2008년부터 2018년까지 악성 근골격계 종양으로 진단받고 PET/CT를 촬영한 환자 251명 중 72명의 환자를 선별하여 후향적 분석을 시행하였다. 림프절 전이가 의심되는 환자군은 조직검사를 시행하였다. 분석은 의무기록, 임상정보, PET/CT 영상 및 판독 소견, 병리 결과를 통해 시행하였으며, 임상경과 및 병리검사 결과를 PET/CT 결과와 비교하여 PET/CT의 정확도를 평가하였다. 결과: 환자의 나이는 14세에서 88세까지 분포하였고, 평균 추시 기간은 2.4년이었으며, 22명에서 림프절의 전이가 확인되었다. 육종 및 비육종 종양에서 PET/CT 영상의 민감도, 특이도, 양성예측도, 음성예측도는 전문가의 소견을 함께 고려할 경우 상당히 상승하는 것을 확인하였다. 결론: 본 연구를 통하여 전문가의 소견을 함께 고려한다면, 림프절의 전이를 발견하는 데 PET/CT의 유용성은 증가할 것으로 생각된다.

• Journal of Electrical Engineering and Technology
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• 제9권6호
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• pp.2089-2097
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• 2014

Negative corona onset characteristics of the stranded conductors based on the ultra-high voltage (UHV) corona cage were studied in the paper. Based on the corona self-sustaining criterion in extreme uneven electric fields and the secondary emission process of the photoelectrons, the corona onset calculation model in the UHV corona cage is established and the corona current tests of the single LGJ900-75, 6 bundle LGJ900-75, 8 bundle LGJ400-35 conductors in dry and rain conditions were done in the UHV corona cage, and the rain rates are 2.4 mm/h, 20 mm/h and 30 mm/h. Corona onset electric field strength is gained by E-I tangent method, and the onset electric field strength in dry condition proves that the calculation model can be used to calculate the corona onset characteristics of the bundle conductors in the UHV corona cage. A further analysis proves that: the negative corona onset voltage of the conductor increases with the bundle number and the diameter of the sub conductor, but decreases with the bundle space in the corona cage. The onset electric field strength is influenced little by bundle space and bundle number, but decreases with the increase of the diameter of the sub-conductor. The surface irregularity coefficient decreases with the rain rate.

• BLOOD RESEARCH
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• 제53권4호
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• pp.281-287
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• 2018

Background Bone marrow involvement (BMI) affects the lymphoma stage, survival, and treatment. Bone marrow biopsy (BMB) and fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET/CT) are useful techniques to detect BMI. Both have advantages and disadvantages. We aimed to identify factors that could be used to predict BMI with positive and negative results on PET/CT compare them with BMB in newly diagnosed patients with lymphoma. Methods We included 22 non-Hodgkin and 16 Hodgkin lymphoma patients in this single center study. All patients had PET/CT examination and BMB before treatment. BMI in BMB was reported as negative or positive. Bone marrow was classified into 3 types by FDG uptake on PT/CT; diffuse involvement, focal involvement, and normal bone marrow. Results PET/CT and BMB results were concordant (7 positive, 15 negative) in 22 patients (57%). We evaluated concordant and discordant patient characteristics and risk-stratified patients for BMI. Our findings suggest that patients with diffuse FDG uptake on PET/CT, especially patients with advanced age and low platelet and white blood cell counts, are likely to have BMI and could potentially forego BMB. Patients with negative PET/CT findings and no significant laboratory abnormalities are very unlikely to have BMI. Conclusion Our results suggest that BMI should not be decided solely based PET/CT or BMB findings. It is reasonable to use both diagnostic assays along with clinical and laboratory findings. PET/CT result, clinical and laboratory findings could be useful for predicting BMI in patient for whom BMB is contraindicated.

• 한국연소학회:학술대회논문집
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• 한국연소학회 2004년도 제29회 KOSCI SYMPOSIUM 논문집
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• pp.169-174
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• 2004

The NOx emission characteristics with oxygen enrichment in nonpremixed counterflow and coflow jet flame of $CH_4$ fuel have been investigated numerically. A small amount of nitrogen is included in oxygen-enriched combustion, in order to consider the inevitable $N_2$ contamination by air infiltration. The results show that the initial increase of NO with increasing oxygen enrichment is due to increasing temperature and residence time, while its subsequent decrease above 75% oxygen is due to decreasing the consumption rate of nitrogen. When oxygen addition exceeds 30%, Thermal NO gradually becomes the dominant production pathway and Prompt NO becomes negative pathway for net NO production rate. It is also seen that Thermal NO plays an important role in NO reduction when strain rate increase in oxygen-enriched combustion. Finally, the results of EINOx with oxygen enrichment in coflow jet flame show the similar profile with those of conterflow flame. It is confirmed that, with leakage of 1% nitrogen in the oxidizer stream, the corresponding EINOx is eight times of that emitted from regular $CH_4$/Air flame.

• JSTS:Journal of Semiconductor Technology and Science
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• 제14권5호
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• pp.588-593
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• 2014

Current crowding problem can worsen the internal quantum efficiency and the negative-voltage ESD of InGaN-based LEDs. In this paper, by using photon emission microscope and thermal emission microscope measurement, we confirmed that the electric field and the current of the InGaN-based LED sample are crowded in specific regions where the distance between p-type metal contact and n-type metal contact is shorter than other regions. To improve this crowding problem of electric field and current, modified metal contact geometry having uniform distance between the two contacts is proposed and verified by a numerical simulation. It is confirmed that the proposed structure shows better current spreading, resulting in higher internal quantum efficiency and reduced reverse leakage current.

• Clinical and Experimental Pediatrics
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• 제63권3호
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• pp.88-95
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• 2020

Accurate localization of the seizure onset zone is important for better seizure outcomes and preventing deficits following epilepsy surgery. Recent advances in neuroimaging techniques have increased our understanding of the underlying etiology and improved our ability to noninvasively identify the seizure onset zone. Using epilepsy-specific magnetic resonance imaging (MRI) protocols, structural MRI allows better detection of the seizure onset zone, particularly when it is interpreted by experienced neuroradiologists. Ultra-high-field imaging and postprocessing analysis with automated machine learning algorithms can detect subtle structural abnormalities in MRI-negative patients. Tractography derived from diffusion tensor imaging can delineate white matter connections associated with epilepsy or eloquent function, thus, preventing deficits after epilepsy surgery. Arterial spin-labeling perfusion MRI, simultaneous electroencephalography (EEG)-functional MRI (fMRI), and magnetoencephalography (MEG) are noinvasive imaging modalities that can be used to localize the epileptogenic foci and assist in planning epilepsy surgery with positron emission tomography, ictal single-photon emission computed tomography, and intracranial EEG monitoring. MEG and fMRI can localize and lateralize the area of the cortex that is essential for language, motor, and memory function and identify its relationship with planned surgical resection sites to reduce the risk of neurological impairments. These advanced structural and functional imaging modalities can be combined with postprocessing methods to better understand the epileptic network and obtain valuable clinical information for predicting long-term outcomes in pediatric epilepsy.

• International Journal of Automotive Technology
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• 제8권6호
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• pp.697-704
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• 2007

Recently, a variable valve timing system has been widely adopted in internal combustion engine in order to improve the fuel economy and torque at low engine speed. In addition, it is known that varying valve timing according to the various engine operations could reduce exhaust gas, especially NOx, because of residual gas by valve overlap. In this study, to improve the low exhaust gas and fuel economy at part load condition, the residual gas and back flow of exhaust gas due to valve overlap were calculated computationally. Moreover, the characteristics of engine performances and NOx formations were investigated with the experiment of combination of intake and exhaust valve timing condition. Under these various valve operating conditions, the effects of both the positive valve overlap and negative valve overlap(valve underlap) were examined simultaneously. Finally, the characteristics of cyclic THC emission were analyzed by using Fast Response FID(FR-FID) in the cylinder, intake port and exhaust port positions. Besides, the effect of the different gradients of the valve timing change on engine performance was investigated and an optimum control strategy was suggested.

• 한국대기환경학회지
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• 제28권2호
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• pp.190-202
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• 2012

Emissions of air pollutants and greenhouse gases (GHGs) by aircraft at the Gimhae International Airport (GIA) were investigated using the Emissions and Dispersion Modeling System (EDMS) version 5.1.3. The number of Landing and Take-Off (LTO) at the GIA for aircraft B737 was dominant, accounting for more than 60% of the total LTOs. For air pollutant emissions, CO was the most dominant pollutant by aircraft, followed by $NO_x$, VOCs, $SO_x$, etc. The emissions of CO, $NO_x$, and VOCs in 2009 (and 2010) at the GIA were 974 (968), 447 (433), 118 (122) ton/yr, respectively. The emissions of GHGs such as $CO_2$, $CH_4$, and $N_2O$ in 2009 (and 2010) were 110,795 (111,114), -0.157 (-0.151), and 1,989 (1,998) ton/yr, respectively. The negative number in $CH_4$ emission represents the consumption of atmospheric $CH_4$ in the engine. In addition, the emissions of most air pollutants (except for $PM_{10}$) and GHGs were estimated to be high in Taxi-Out and Climb-Out modes.

• 환경위생공학
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• 제7권2호
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• pp.141-152
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• 1992

Simple correlation analysis, factor analysis, and multi-verite analysis have been performed to analyze the relationship between air pollution and meteorological factors for air pollution and meteorological data measured at Kwanghwamun in Seoul during the period of one year (January 1990" December 1990). As a result of simple correlation and factor analysis, $SO_2$, TSP and CO concentrations have shown high negative correlation with temperature and among these indicating that these are related with pollutants emission trend based upon heating fuel usage. Ozone has a good correlation with solar radiation and relative humidity to have a closed relation with $0_3$ generation reaction mechanism. The result of multi-variate correlation analysis shows that the concentration of $SO_2$ and CO are adequate for correlation model with ambient temperature and wind speed and 0$_{3}$ concentrations are adequate for that with solar radiation and wind speed. $SO_2$ and CO levels are considered to be affected first of all by heating fuel usage as a emission source and wind speed as a dispersion effect. The $SO_2$ concentration in the condition that the temperature fall below zero is explained by multiplicative model with wind speed, only one variable.

• 항공우주기술
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• 제8권2호
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• pp.33-40
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• 2009

본 논문에서 [1MHz-47MHz]의 주파수 범위에서의 통신해양기상위성과 정지궤도 발사체와의 예비적인 EMC 해석 과정을 기술한다. 정지궤도용 발사체 최대 복사 방출 한계치와 위성의 최대 복사 감응 한계치와 비교한다. 전자파 호환이 되지 않는 발사체로는 land launch와 소유즈가 있다. 만약에 이 발사체가 선정된다면 위성체 레벨에서 전자파 시험을 통하여 검증하여야 한다.