• Title/Summary/Keyword: near work

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Identification of Pharmaceuticals for process control using Near Infrared Spectroscopy and Soft Independence modeling of Class Analogy (SIMCA)

  • Cho, Chang-Hee;Kim, Hyo-Jin;Maeng, Dae-Young;Seo, Sang-Hun;Cho, Jung-Hwan
    • Near Infrared Analysis
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    • v.1 no.2
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    • pp.29-33
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    • 2000
  • The identification step of raw drug materials is an indispensible procedure in the GMP manufacturing process within the pharmaceutical industry. However, wet chemistry methods for identification of drug materials, used by the various Pharmacopeia are time-consuming and expensive steps. In this paper, near-infrared spectroscopy (NIRS) has been developed for identifying eleven drug substances including calcium pantothenate, cefaclor, cefoperazone, cephradine, dextromethorphan, ehtambutol, nicotinamide, pyrozinamide, tramadol, vitamin C, and vitamin E. Also the aim of ths work is to consturct a new algorithm for calibration model using soft independence modeling of class analogy (SIMCA) with Malinowskis Indicator Function (IND), which is used for finding the number of principal components of each class of the SIMACA model. The use of NIR technique with pattern recognition to qualify raw materials can make it possible to monitor process in real time as well as to control all procedures in the pharmaceutical industry. As the result, the samples identified of 183 different batches from 11 different compounds were separated clearly by SIMCA with 2nd derivative spectra in the NIR region of 1100∼2400 nm.

A Study on The Risk Level of Work Types in Urban Railway Construction (도시철도 건설공사의 공종별 위험도에 관한 연구)

  • Lee, Jong-Bin;Han, In-Kuk;Chang, Seong Rok
    • Journal of the Korean Society of Safety
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    • v.31 no.2
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    • pp.98-103
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    • 2016
  • The goals of this study were to investigate some significant factors to judge level of safety at urban railway construction field and to analyze degree of risk by work classification. Currently, there are lots of construction fields for the urban railway for national transportation, and our government also planned constructing more urban railway in near future. However, most of the researches on safety neglected the degree of risk factors on the urban railway construction field. Safety managers participated in the brainstorming session for deriving decision criteria of the degree of risk (i.e., significant factors). Then, they were asked to answer a structured questionnaire which was developed for deriving most important factors. Finally, the analytic hierarchy process (AHP) was used to analyze level of risk by work classification. The following results were obtained. First, total twelve factors judging degree of risk were found in the brainstorming session. Second, the questionnaire showed four significant factors, including adjacency of obstacle, intensity of work, unsafe condition and work space. Third, the results of AHP showed civil work is the most dangerous work among 6 work types. The results could be used to give the safety management priority on accident prevention efforts among several hazards and to reduce degree of risk in construction field of the urban railway.

Forced Convection Correlation for Single Circular Fin-tube Heat Exchanger (단일 원형휜-원형관에 대한 강제대류열전달 상관식)

  • 강희찬;강민철
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.16 no.6
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    • pp.584-588
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    • 2004
  • This work was performed to investigate the heat transfer characteristics of the circular fin-tube heat exchanger. This paper contains the experimental data for the seven kinds of fin geometries. The correlation of Stasiulevicius agreed with the experimental data at high Reynolds number, however not well at low Reynolds number. The Nusselt number was well correlated with Graetz number, and showed a transition near Gz=10. An empirical correlation proposed in the present work agreed well with the experimental data.

Numerical Analysis of Heat and Mass Transfer in a Calandria Based Reactor

  • Tupake Ravindra S;Kulkarni PS;Rajan NKS
    • 한국전산유체공학회:학술대회논문집
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    • 2003.10a
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    • pp.281-282
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    • 2003
  • Numerical investigations are carried out to study the mass flux and temperature distribution in a calandria using a 3-D RANS code. The computations made for simulations of flow and convective heat transfer with near-to working conditions. The work provides an estimate of the safe working limits of the heat dissipation by virtue of prediction of the 'hot spots' in the calandria. The work assumes significance for preliminary designs of the reactors and for detailed critical parametric analysis that would be otherwise more expensive.

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An analysis of posttraumatic stress disorder(PTSD) of fire fighters (소방공무원의 현장충격 스트레스에 대한 분석)

  • Kim, Jee-Hee
    • 한국방재학회:학술대회논문집
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    • 2008.02a
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    • pp.381-384
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    • 2008
  • The purpose of this study is to evaluate influence factors of secondary traumatic stress, burnout, and physical symptoms which were experienced by fire fighters. The questionnaire research was done for field service fire fighters who work in Korea. I analyzed 358 questionnaires and the questionnaires consisted of stress scale, work force, burden of physical symptoms, and self-control to stress. Through this study I will propose the solution for the posttraumatic stress disorder(PTSD) for the near future.

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Quantitative analysis by the CARNAC procedure

  • Davies, Anthony M.C.;Fearn, Tom
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.1124-1124
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    • 2001
  • CARNAC is a procedure for obtaining quantitative analysis of a sample by comparison of the NIR spectra of the unknown sample with a database of a large number of samples with NIR spectral and compositional data. The method depends on the compression of the NIR database followed by a modification of the compressed data which emphasizes the required analyte. The method identifies a few very similar samples and the value of the required analyte is calculated from a weighed average of the analyte values for the selected similar samples. The method was originally described at Chambersburg IDRC in 1986 and in the Proceedings of the FT Conference of 1987. This contribution will describe recent work on utilising new methods for both compression and modification.

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Signal Integrity Analysis of High Speed Interconnects In PCB Embedded with EBG Structures

  • Sindhadevi, M.;Kanagasabai, Malathi;Arun, Henridass;Shrivastav, A. K.
    • Journal of Electrical Engineering and Technology
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    • v.11 no.1
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    • pp.175-183
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    • 2016
  • This paper brings out a novel method for reducing Near end and Far end Crosstalk using Electromagnetic Band Gap structures (EBG) in High Speed RF transmission lines. This work becomes useful in high speed closely spaced Printed Circuit Board (PCB) traces connected to multi core processors. By using this method, reduction of −40dB in Near-End Crosstalk (NEXT) and −60 dB in Far End Crosstalk (FEXT) is achieved. The results are validated through experimental measurements. Time domain analysis is performed to validate the signal integrity property of coupled transmission lines.

The Values of J-integral and Shapes of Plastic Zone Near a Crack Tip of Cracked Panels by the $\rho$-Version of F.E.M. ($\rho$-Version 유한요소법에 의한 균열판의 소성역 형상과 J-적분값 산정)

  • 홍종현;우광성
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 1999.04a
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    • pp.42-49
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    • 1999
  • Because the linear elastic tincture analysis has been proved to be insufficient in predicting the failure of cracked bodies, in recent years, a number of fracture concepts have been studied which remain applicable in the presence of large-scale plasticity near a crack tip. This work thereby presents a new finite element model, as accurate as possible, to analyze plane problems of ductile fracture under large-scale yielding conditions. Based on the incremental theory of plasticity, the p-version finite element analysis is employed to account for the values of J-integral, the most dominant fracture parameter, and the shape of plastic zone near a crack tip by using the J-integral method and equivalent domain integral method. The numerical results by the proposed model are compared with the theoretical solutions in literatures and the numerical solutions by the i,-version of F.E.M.

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Near Net Shape Design of an Exhaust CAM for Vessel Engine (선박엔진용 배기캠의 정밀성형설계)

  • Yeom, J.T.;Kim, J.H.;Kim, J.H.;Hong, J.K.;Lee, J.S.
    • Transactions of Materials Processing
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    • v.18 no.8
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    • pp.589-595
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    • 2009
  • The hot forming process of an exhaust CAM for vessel engine was designed by finite element(FE) simulation and experimental analysis. An aim of process design was to achieve the near-net shaped CAM forgings by hot forging process. Based on the compression test results of the low alloy steel, power dissipation map was generated using the the dynamic materials model(DMM). From the map, the initial heating temperature was determined as 1200oC. FE analysis was simulated to predict the formation of forging defects and deformed shape with different forging designs. Optimum process design suggested in this work was made by comparing with the CAM for vessel engine manufactured by actual forging process.

Applicability of Safe Blast Vibration Limits to the Blasting Work near Safety Related Structures (안전관련 구조물 근접시공시 발파진동 허용기준의 적용성에 관하여)

  • 류창하;서우춘;정소걸;이종림;주광호;이대수
    • Tunnel and Underground Space
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    • v.4 no.3
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    • pp.287-296
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    • 1994
  • Safety-related structures of power plants have to be protected against the effects of possible hazards and natural phenomena. Earthquakes are considered a major dynamic design loading as a requirement of plant design, but the effects of blast-induced vibratons are not. Due to the difficulties of obtaining construction site for new plants, following ones are inevitably being built in the site adjacent to existing power plants. Therefore considerable thought has been recently given to the dynamic loading generated by blasting works near the plants. In this paper, discussed is applicability of existing vibration standards and industrial codes to the blasting works near safety related structures. Also evaluated are the parameters for the safe vibration limits such as measure of vibration level, frequency consideration, structure response, propagation equation, etc.

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