• 제목/요약/키워드: natural testing

검색결과 705건 처리시간 0.028초

연교산과 구성약재에 대한 항암 및 항산화효과 (Cytotoxicity and Antioxidant Activities of the Yeonkyo-san and Its ingredients)

  • 이진태;이창언;손준호;이진영;박태순;이인철;천순주;편정란;지선영;조철훈;안봉전
    • 대한본초학회지
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    • 제20권3호
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    • pp.19-27
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    • 2005
  • Objectives : The antioxidant activities of Yeonkyo-san and its ingredient were investigated for industrial application. Methods : We experimented radical scavenging effect, superoxide dismutase and cytotoxicity effect of various cancer cell. Results : The result were obtained as follows : Primary testing of cytotoxicity of Yeonkyo-san and ingredient was done for G361. B16F10, MDA and A549 cell lines. Yeonkyo-san and ingredient water extract, ethanol extract showed cytotoxicity of over 90% respectively against cell line. The electron donating ability(EDA) of water extract from the Yeonkyo-san was higher than 60%, ethanol extract from the Yeonkyo-san was over 80% at 1000 ppm. The electron donating ability(EDA) of water extract and ethanol extract from the Yeonkyo-san ingredients were increased as well. SOD-like activity was high as 75% in 700 ppm, it was increased. All the other samples showed less than 40% SOD-like activity. Conclusions : The results indicated that water extract and ethanol extract of Yeonkyo-san and ingredient can be used as a natural ingredient with biological functions in cosmetic and food composition.

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비대칭성 고관절 회전각을 지닌 슬개대퇴통증증후군 환자의 치료적 접근 - 사례연구 (The Effects of Therapeutic Approach of Patellofemoral Pain Syndrome with Asymmetrical Hip Rotation : Case Study)

  • 장현정;김선엽;김호봉
    • 대한정형도수물리치료학회지
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    • 제17권2호
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    • pp.41-48
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    • 2011
  • Background: Patellofemoral pain syndrome is very common knee problem and altered hip rotation may play a role in patellofemoral pain. The purpose of this case study is to describe the manual therapy of and the therapeutic exercise for a patient with asymmetrical hip rotation and patellofemoral pain. Method: The patient was a 29 years old woman with an 3 month history of anterior right knee pain, without known trauma or injury. Prior to intervention, her score on the VAS was Max 6 to Min 4. Left hip internal rotation was less than right hip internal rotation, and manual muscle testing showed weakness of the left hip internal rotator and abductor muscles. The intervention consisted of manual therapy and therapeutic exercise for three times a weeks, two weeks for increasing right hip medial rotation, improving left hip muscle strength, and eliminating anterior right knee pain. Result: After intervention for 2weeks, passive left and right hip medial rotations were symmetrical, and her right hip internal rotator and abductor muscle grades were Good plus. Her VAS score was Max 2 to Min 0. Conclusion: Manual therapy and therapeutic exercise is effective in improving for patient had patellofemoral pain with pattern of asymmetrical hip rotation.

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발효소시지 제조에 적합한 스타터 선발 (Screening of Lactic Acid Bacteria as a Starter Culture in Fermented Sausage)

  • 유선아;서승호;박성은;손홍석
    • 한국식품영양과학회지
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    • 제43권8호
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    • pp.1289-1295
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    • 2014
  • 본 연구에서는 전통발효식품 13종과 천연물 4종에서 27균주를 분리한 후 생육속도가 빠르고 pH 저하 능력이 우수한 3종의 균주를 1차 선발하였으며, 분자생물학적 방법을 이용하여 동정한 결과 Staphylococcus warneri, Sta. epidermidis, Lactobacillus plantarum과 99% 상동성을 보였다. 선발된 3균주의 발효소시지 스타터로서 이용가능성을 알아보기 위해 발효소시지의 환경과 유사한 model-system에서 배양하며 pH 저하 능력, 총산 생성 능력, 생육 능력, 아질산염 소거 능력을 발효소시지의 스타터로 많이 사용되고 있는 5균주 및 상업용 2균주와 비교하였다. Modelsystem에서 pH 저하능과 총산 생성능, 생육능은 관련성이 있었으며, 상업용 균주보다 분리한 Sta. epidermidis DO 10-1, Lac. plantarum MLK 14-2가 우수한 결과를 나타내었다. 아질산염 소거능의 경우에도 분리한 3균주가 상업용 균주보다 상대적으로 빠른 속도를 보였다. 분리한 3균주는 발효소지지 스타터로서의 발효 소거 능력은 우수할 것으로 보이지만 Staphylococcus는 잠재적인 위험성이 제기되는 균주이므로 Lac. plantarum이 발효소지지 제조에 가장 적합할 것으로 사료된다.

Effects of Clothing Material Dyed with Astringent Persimmon Extract upon Exercise-Induced Thermal Strain and Sensory Responses in a Warm Environment

  • Park, Shin-Jung;Shin, Hye-Sun;Chung, Hee-Chung
    • International Journal of Human Ecology
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    • 제16권2호
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    • pp.1-9
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    • 2015
  • This study investigated the effects of persimmon-dyed clothing materials upon thermophysiological responses and subjective comfort sensations during exercise and rest in a warm environment. Six healthy, untrained women participated in two separate testing sessions, with cotton materials dyed with astringent persimmon extract (DC) and undyed cotton materials (UDC). The physical characteristics associated with heat and moisture transfer were improved in DC; also, stiffness, anti-drapery stiffness and crispness in the primary hand values were higher in DC. The experimental protocol consisted of a 10-min rest, 15-min exercise on a treadmill (at ${7km{\cdot}h^{-1}}$) and 25-min recovery at $28{\pm}0.2^{\circ}C$ and $50{\pm}3%\;RH$. The results were as follows: When wearing DC rather than UDC, mean body temperature, heart rate, heat storage and body mass loss were significantly lower during the whole experimental period. Clothing microclimate temperature showed different profiles between the two clothing materials, being lower with DC than UDC during the first half of exercise and the second half of recovery. Clothing microclimate humidity was significantly lower with DC than UDC during the whole experimental period. When wearing UDC, subjects felt significantly warmer and less comfortable during exercise, and sensed greater humidity during exercise and recovery. These results suggest that eco-friendly clothing materials dyed with astringent persimmon extract can reduce exercise-induced heat load and improve subjective sensations when exercising and resting in a warm environment, due to greater heat dissipation from the body to the outside environment compared with undyed clothing materials.

Cold Room을 이용한 모형빙의 재료특성에 관한 실험적 연구 (An Experimental Study for the Mechanical Properties of Model Ice Grown in a Cold Room)

  • 김정현;최경식;정성엽;서영교;조성락;이춘주
    • 한국해양공학회지
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    • 제22권3호
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    • pp.64-70
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    • 2008
  • A full-scale field experiment is an important part in the design of ships and offshore structures. Full-scale tests in the ice-covered sea, however, are usually very expensive and difficult tasks. Model tests in a refrigerated ice tank may substitute this difficulty of full-scale field tests. One of the major tasks to perform proper model tests in an ice towing tank is to select a realistic material for model ice which shows correct similitude with natural sea ice. This study focuses on the testing material properties and the selection of model ice material which will be used in an ice model basin. The first Korean ice model basin will be constructed at the Maritime & Ocean Engineering Research Institute (MOERI) in 2009. With an application to the MOERI ice model basin, in this study the material properties of EG/AD/S model ice of IOT (Institute for Ocean Technology) Canada, were tested. Through comprehensive bending tests, the elastic modulus and the flexural strength of EG/AD/S model ice were evaluated and the results were compared with published test results from Canada. Instead of using an ice model basin, a cold room facility was used for making a model ice specimen. Since the cold room adopts a different freezing procedure to make model ice, the strength of the model ice specimen differs from the published test results. The reason for this difference is discussed and the future development for a making model ice is recommended.

항균성물질이 함유된 세라믹 LDPE필름의 항균효과 및 식품의 저장성 (Antimicrobial Activity and Food Storage of LDPE Ceramic Film Containing Antimicrobial Agents)

  • 김현수;성림식;유대식
    • KSBB Journal
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    • 제15권6호
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    • pp.600-604
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    • 2000
  • 다양한 식품의 미생물에의한 변패를 억제하고 저장성을 높 일수 있는 포장필름을 개발하기위하여, 미생물이 생산하는 천연 항균성 물질을 홉착시킨 합성 세라믹올 첨가하여 세라 믹 LDPE 필륨을 제조하였다. 천연 항균제로는 methanol자화 방선균 MO-16 및 MO-17균이 생산한 항세균제와 새로이 분 리한 방선균 No. 31이 생산한 항진균제를 사용하였다. 방선 균 No. 31이 생산한 항진균성 불질은 배양 4일째 항균효과가 우수하였으며, $121^{\circ}C$에서 15분간 열처리시에도 항균력이 유 지되는 내열성이 확인되었다. 제조한 세라믹 LDPE 필름의 미생불 생육 억제효과를 검토한 결과 조분쇄한 돈육의 경우 포장하여 실온 및 $4^{\circ}C$에서 보존시 시판필름에 비해 미생물 생육 억제효과가 우수하였다. 고제배지에 제조필름을 첨가하 여 E. coli에 대한 항균효과를 검토한 결과 첨가량에 따라 항 균효과가 우수한 것이 입증되었다 제조펼름으로 포장한 6종 류의 식품에 대한 저장성을 검토한 결과 시판필름에 비해 저 장성이 우수한 것이 확인되었으며 특히 양송이에 대한 저장 효과가 우수하였다.

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젊은 성인에서 위험 회피 기질과 우전두엽 및 좌두정엽과의 관련성 : 피질두께 분석 (The Relationship between Harm Avoidance Temperament and Right Frontal and Left Parietal Lobes in Young Adults : A Cortical Thickness Analysis)

  • 김다정;류영욱;박영준;안태주;최병주;신이경;김태석
    • 생물정신의학
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    • 제17권4호
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    • pp.203-209
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    • 2010
  • Objectives : Increasing evidence suggests the presence of neurobiological bases for temperamental characteristics in humans. Brain correlates of harm avoidance(HA) have been most extensively studied using functional and structural brain imaging methods due to its potential link with anxiety and depressive disorders. To date, however, we are not aware of any reports that have examined the potential relationship between HA levels and regional cortical thickness. The aim of the current study is to examine the cortical thickness which is associated with HA temperament in healthy young subjects. Methods : Twenty-eight young, healthy individuals(13 men and 15 women, mean age, $29.4{\pm}6.3$ years) were screened for eligibility and administered the Korean version of the Cloninger's Temperament and Character Inventory and underwent high-resolution structural magnetic resonance imaging scanning. Results : HA was associated with cortical thickness in the right superior frontal cortex and in the left parietal cortex, adjusted for age and sex and corrected for multiple comparisons using the permutation testing method. Conclusion : Individual temperamental differences in HA are associated with structural variations in specific areas of the brain. The fact that these brain regions are involved in top-down modulations of subcortical fear reactions adds functional significance to current findings.

가스 파이프라인 상의 압력 부식에 의한 흠집 검사를 위한 원격 와전류 탐상 기술 (Remote Field Eddy Current Testing for Detection of Stress Corrosion Cracks in Gas Transmission Pipelines)

  • 김대원
    • 한국자기학회지
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    • 제16권6호
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    • pp.305-308
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    • 2006
  • Magnetic flux leakage(MFL) 신호를 이용하여 비파괴 검사 신호를 획득하는데 주로 사용하는 감지기 또는 금속 덩어리를 의미하는 pig 이용 기술은 일반적으로 천연 가스 전송에 사용되는 강철 파이프라인 상의 대량 부식 흔적을 감지하는데 널리 이용 되어지고 있다. 이를 대체할 수 있는 비파괴 검사 기술의 양상에 대하여 소개 하자면, 지하에 매설된 가스 파이프라인의 바깥 면에 가로축을 따라 난, 부식에 의한 결함에 일반적으로 동반하는 '압력에 의한 부식 흠집(Stress Corrosion Crack : SCC)'을 탐지하는 기술이 있다. 본 논문은 가스 파이프라인 상의 가능성 있는 SCC 검출 장치로서 탐촉자의 원거리에 형성된 다상 회전 전자장 활용 기술에 대하여 논하고 있다. Pig 원형에 대한 묘사와 비파괴 신호 검사용 탐촉자에 대한 설명이 덧붙여져 있으며 결함 검지장치의 유한 요소 모델링과 연관한 부분에 관하여도 발전적으로 논하였다. 테스트 용 pig를 이용한 초기 실험 결과는 본 논문에서 보이고 있는 비파괴 검사 양식이 가스 파이프 라인의 가로축을 따라 발생한 결함에 매우 민감하게 반응하고 있음을 보이고 있다.

Toxicity and Safety Profiles of Methanolic Extract of Pistacia integerrima J. L. Stewart ex Brandis (PI) for Wistar Rats

  • Sharwan, Gotmi;Jain, Parag;Pandey, Ravindra;Shukla, Shiv Shankar
    • 대한약침학회지
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    • 제19권3호
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    • pp.253-258
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    • 2016
  • Objectives: The goals of this research were to evaluate acute (single-dose) and sub-acute (repeated-dose) toxicity profiles of methanolic extract of Pistacia integerrima J. L. Stewart ex Brandis (PI) for Wistar rats and to assess the safety profile of PI by observing physiological changes, mortality, changes in body weight, the histopathology of body organs, the hematology and the biochemistry of the animals. Methods: The toxicity profile of PI was evaluated using Wistar rats of both sexes. Animals were divided into four groups: Group 1; control group (normal saline), Group 2; PI-1 (250 mg/kg), Group 3; PI-2 (500 mg/kg), Group 4; PL-3 (1,000 mg/kg). An acute-toxicity study in which animals received a single dose of PI extract (2,000 mg/kg) and were then observed for 14 days for changes in skin, fur, eye color, mucous membrane secretions and excretions, gait, posture, and tonic or clonic movements was performed according to guideline 425 of the Organization of Economic and Corporation Development (OECD). In the repeated-dose toxicity study (OECD - 407) animals received a daily dose of PI extract for 28 days (4 weeks). The parameters observed in this study include body weight, hematology and biochemistry of the animals. Results: In the acute toxicity study, no mortalities or changes in behavior were noted in the animals. The repeated-dose toxicity study was also devoid of any toxicity in the animals during the 28 days of testing with PI extract. The extract did not alter- the body weight, hematology or biochemistry of the animals. The methanolic extract of PI was to be found safe to the no-observed-adverse-effect-level (NOAEL) for the single-dose and repeated-dose toxicity tests in rats. Conclusion: The methanolic extract of PI was devoid of toxicity; hence, it can be used for various ayurvedic preparations and treatments of diseases.

USN 기술을 이용한 사면붕괴모니터링 시범시스템 개발 (Development of a Prototype System for Slope Failure Monitoring Based on USN Technology)

  • 한재구;김균태
    • 한국건설관리학회:학술대회논문집
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    • 한국건설관리학회 2007년도 정기학술발표대회 논문집
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    • pp.316-321
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    • 2007
  • 국내에서 산사태 등 사면붕괴로 인한 재해의 사망자수는 전체 자연재해 사망자수의 약 24%에 해당된다. 이러한 사면붕괴는 주로 태풍 및 집중호우가 발생하는 시기에 집중되고 있다. 그러나 지금까지 사면붕괴 예방을 위한 연구는 소홀하게 취급되어 왔다. 한편 USN(Ubiquitous Sensor Network)은 컴퓨팅능력과 무선통신능력을 지난 센서노드들을 이용하여 자율적인 네트워크를 형성하고, 서로 간에 정보를 전달하는 것이다. 따라서 USN기술은 유비쿼터스 사회의 핵심기술로 부각되고 있으며, 이 기술을 활용하기 위한 다양한 연구가 진행되고 있다. 본 연구의 목적은 이와같은 USN기술을 이용하여 사면붕괴 모니터링 시범시스템을 개발하는 것이다. 이를 위하여 본 연구에서는 한개의 신축계와 두개의 지표경사계를 사용하였으며, 센싱된 실시간 사면거동정보를 수집${\cdot}$변환하고 데이터베이스 서버로 전송하여 저장하는 모듈을 구현하였다. 또, 저장된 데이터를 손쉽게 분석할 수 있는 프로그램을 개발하였다. 개발된 시범시스템은 한국건설기술연구원의 테스트베드에서 현장적용성 실험을 수행하여 타당성을 검증하였다.

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