• Animal cells and systems
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• 제14권2호
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• pp.91-98
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• 2010

Male rats were given a single injection of iron, and temporal changes in iron content and iron-induced effects were examined in heart cellular fractions. Over a period of 72 h, the contents of total and labile iron, reactive oxygen species, and NO in tissue homogenate, nuclear debris, and postmitochondrial fractions were mostly constant, but in mitochondria they continuously increased. An abrupt decrease in membrane potential and NAD(P)H at 12 h was also found in mitochondria. The respiratory control ratio was reduced slowly with a slight recovery at 72 h, suggesting uncoupling by iron.While the ATP content of tissue homogenate decreased steadily until 72 h, it showed a prominent increase in mitochondria at 12 h. Total iron and calcium concentration also progressively increased in mitochondria over 72 h. Enzyme activity of the oxidative phosphorylation system was significantly altered by iron injection: activities of complexes I, III, and IV were reduced considerably, but complex II activity and the ATPase activity of complex V were enhanced. A reversal of activity in complexes I and II at 12 h suggested reverse electron transfer due to iron overload. These results support the argument that mitochondrial activities including oxidative phosphorylation are modulated by excessive iron.

• 통합자연과학논문집
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• 제7권3호
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• pp.214-218
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• 2014

The main objective of this study is to analyse the influence factors of snowfall enhancement by glaciogenic seeding in a mountainous area. Twenty-five seeding experiments have been conducted during the period of February to April 2010. To use two rates seeding experiments (SR1: $1.04g\;min^{-1}$, SR2: $2.08g\;min^{-1}$) have been tested to get an appropriate ratio for snowfall enhancement at Daegwallyeong area. The conditions of seeding are able as followings: surface temperature <$0^{\circ}C$, wind speed <5 m/s, wind direction between 0 and $130^{\circ}$. The experiment results indicated that in the case of SR1 was more effective than SR2. The number of small ice particles below 1.0 mm was increased during seeding period measured by PARSIVEL disdrometer near generator. Most of snowfall enhancement by seeding was observed the inflow of the easterly wind blew in toward Gangwon regions from the East Sea and the supersaturated supercooled liquid water due to orographic effect.

• 한국지진공학회논문집
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• 제25권1호
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• pp.33-42
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• 2021

The design response spectrum presented in the seismic design standard reflects the characteristics of the tectonic environment at a site. However, since the design response spectrum does not represent the ground motion with a specific earthquake magnitude or distance, input ground motions for response history analysis need to be selected reasonably. It is appropriate to use observed ground motions recorded in Korea for the seismic design. However, recently recorded ground motions in the Gyeongju (2016) or Pohang (2017) earthquakes are not compatible with the design response spectrum. Therefore, it is necessary to convert the recorded ground motion in Korea to a model similar to the design response spectrum. In this study, several approaches to adjust the spectral acceleration level at each period range were tested. These are the intrinsic and scattering attenuation considering the earthquake environment, magnitude, distance change by the green function method, and a rupture propagation direction's directivity effect. Using these variables, the amplification ratio for the representative natural period was regressed. Finally, the optimum condition compatible with the design response spectrum was suggested, and the validation was performed by converting the recorded ground motion.

• The Korean Journal of Ecology
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• 제14권2호
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• pp.211-230
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• 1991

The germinatin of e. annuus continued from the middle ofmay to mid-october. The maximum germination occurred on the mid-july. The period bloom of was distingushed amongs the different growth forms ; a orm pr of biennial and a form of pr perennial flowering from the mid-may to mid-september, and a form ps biennial blossom from the beginning of October to earlynovember. the dispersal of seed for(a form pr)occurred from early June to the mid-september. A rotte, germinating from summer to autumn, could classified into several growth forms; individuals without a critical leaf area for bolting until september and October, become a form ps of biennial, whicth did not proceed toreproductive growth unitl the next year, even thought wintering. individuals flowered on 3 years after germination become a form pr of perennial. The growth formular of aform pr of bennial, grown in a pot was w=20.2[1+$3.36{\times}10^3$(-0.062t)]$^{-1}$. The maximum relative growth rate(rgr) was 0.062g/g/day and the maximum net assimlation rate(nar) 0.089g/g/day. Therelative growth among each organ was shown as R=0.12 $T^{1.15}$between the avove-ground part(t) and the below- ground part(r). the relation between the avove-ground part(t) and the ratio of stem weight(wi) was ws/wi=2.56 $T^{0.35}$. n.p.k. was largely distributed on a leaf throughoutthe total growth period. while growing, it tended to decrease on the vegetative organ gut vice versa on the reproductive organ. however, nitrogen was more widely distributed on a leaf then in the reproductive organ.

• Earthquakes and Structures
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• 제16권3호
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• pp.295-310
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• 2019

This study attempts to develop new simplified approximate formulas to predict the fundamental natural periods of vibration (T) for bearing wall systems engaged with special reinforced concrete shear walls (RCSW) under seismic loads. Commonly, seismic codes suggested empirical formulas established by regression analysis of measured T for buildings during earthquake motions. These formulas depend on structure type, building height, number, height and length of SW, and ratio of SW area to base area of structure. In this study, a parametric investigation is performed for T of 110 selected models of bearing RCSW systems with varying structural height, configuration of horizontal plans including building width, number and width of bays, presence of middle corridors and core SWs. For this purpose, a 3D non-linear response time history (TH) analysis is implemented using ETABS v16.2.1. New formulas to estimate T are anticipated and compared with those obtained from formulas of IBC 2012 and ASCE/SEI 7-10. Moreover, the study examines responses of an arbitrarily two selected test model of 60 m and 80 m in height with presence of SWs having middle corridors. It is observed that the performance of the tested buildings is different through arising of considerable errors when using codes' formulas for estimating T. Accordingly, using the present proposed formulas exhibits more reasonable and safer design compared to codes' formulas. The results showed that equitable enhancement is promising to improve T formulas approaching enhanced and accurate estimation of T with reliable analysis, design, and evaluation of bearing RCSW systems.

• 상하수도학회지
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• 제32권6호
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• pp.527-533
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• 2018

Microorganisms detected in the biofilm not only cause secondary pollution of drinking water such as taste, odor and pathogenic disease but also increase the amount of disinfectant due to microbial regrowth during the transportation of tap water. In this work, the influence of C/N ratio in tap water on the characteristics of biofilm growth was examined. The C/N ratio of the tap water sample was controlled at 100:5, 100:10, 100:20, 100:30, and 100:40 by adding appropriate amounts of dextrose and $(NH_4)_2SO_4$. Of the five C/N ratios, heterotrophic plate counts (HPC) was highest at the ratio of 100:10. Following the initial formation in all the five experimental conditions, natural detachment of the biofilm was observed. Extracellular enzyme activity (EEA) analyses showed that the change of the EEA during the experimental period was similar to that of the HPC, demonstrating a positive correlation between HPC and EEA. For TOC concentration in the tap water sample, approximately 75% of the TOC was consumed in 7 days of the experiment and 96% in 28 days. The TOC appeared to be relatively rapidly consumed at the initial phase of the biofilm growth. Consumption pattern of the ammonia nitrogen was different from the TOC consumption pattern showing the different role of ammonia nitrogen on the growth of biofilm.

• 한국산학기술학회논문지
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• 제14권6호
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• pp.3068-3073
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• 2013

근래에 스카이브릿지를 활용하여 연결된 고층구조물의 진동제어성능을 개선하고자 하는 연구가 수행되고 있다. 본 논문에서는 스카이브릿지로 연결되는 두 구조물의 고유진동주기의 차이와 스카이브릿지 설치위치가 진동제어성능에 미치는 영향에 대해서 분석하여 보았다. 이를 위하여 40층과 50층 구조물을 연결된 예제구조물로 선택하였고 두 구조물의 고유진동주기 차이를 1.0배에서 1.5배까지 순차적으로 변경하면서 해석모델을 구성하였다. 각각의 해석 모델에 대하여 KBC2009를 기반으로 생성한 인공지진하중을 입력 하중으로 생성하여 시간이력해석을 수행하였다. 수치해석결과 두 구조물의 고유진동주기차이가 증가할수록, 연결된 층의 높이가 높아질수록 변위 및 속도응답에 대해서 일반적으로 우수한 제어성능을 나타내는 것을 알 수 있었다. 그러나 가속도응답의 경우에는 이러한 경향과 반대되는 제어성능변화를 나타내었다.

• Asian-Australasian Journal of Animal Sciences
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• 제21권7호
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• pp.1015-1026
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• 2008

The influence of dietary beef tallow (BT) versus sunflower oil (SO) on meat quality and apparent digestibility and deposition of individual fatty acids in the whole carcass was investigated in pigs fed diets containing either BT or SO. The diets contained equal amounts of energy in the form of the variable fats and were fed on an iso-energetic, restricted basis. Crude fat in the SO diet was better digested (p<0.001) than in the BT diet. The dietary fat type had no effect on growth performance, physical properties of the carcass and meat quality. The pigs fed the BT diet showed lower (p<0.001) apparent digestibilities for palmitic and linoleic acid, but those of oleic and ${\alpha}$-linolenic acid were not affected. The ratio of deposition in the carcass to intake of digestible fatty acids for the whole feeding period was decreased (p<0.01) for oleic and linoleic acid in pigs fed the SO diet. The pigs fed the SO diet instead of the BT diet had a lower (p<0.05) deposition:intake ratio for mono-unsaturated fatty acids. The calculated minimum de novo synthesis of saturated fatty acids was increased for the SO diet, but that of mono-unsaturated fatty acids was not different. In conclusion, the iso-energetic replacement of BT by SO had a marked impact on the fatty acid composition of tissues, but did not affect carcass and meat quality traits in spite of the marked difference in the deposition of linoleic acid in adipose tissues, loin muscle and the whole body. In addition, it became clear that the type of dietary fat had marked, specific effects on the synthesis and oxidation of fatty acids.

• Toxicological Research
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• 제26권3호
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• pp.185-192
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• 2010

Isaria sinclairii (Cicada Dongchunghacho) was studied as a potential crude natural food in powdered form. The role of tissue fatty acids in relation to the anti-obesity effects of I. sinclairii (IS) was examined by feeding the powder to SD rats ad libitum at 0, 1.25, 2.5, 5 and 10% (calculated about 8 g/kg) of the feed for a period of 3 months and 6 months. The fatty acid composition profile as indicated GC-MS, showed significantly slight dose-dependent increases in the levels of unsaturated fatty acids, particularly, arachidonic acid (C20: 4n6), oleic acid, linoleic acid, eicosadienoic acid, eicosapentaenoic acid (EPA) (C20: 5) concentration in the the ad libitum IS-fed groups compared to the control group in SD abdominal fat over 6 month period. Over viewing of the SD and Ob mice treated Isaria sinclairii powder; there were increases in the single (mono) unsaturated fatty acids ratio but decreases in polyunsaturated fatty acid. In IS-fed groups in proportion to the treatment period, this Dongchunghacho also induced an increase in the level of same result of unsaturated fatty acid in C57BL/6 obese (ob/ob) mice over a 6-month period treatment compared to those given 10% dry mulberry leaf powder (ML) or silkworm powder mixed with the standard diet.

• 한국환경보건학회:학술대회논문집
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• 한국환경보건학회 2003년도 Challenges and Achievements in Environmental Health
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• pp.171-173
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• 2003

Bisphenol A (4,4'-isopropylidenediphenol, C$\_$15/H$\_$16/O$_2$) is the monomer used in the manufacture of polycarbonate. Polycarbonate, in turn, is used in a wide array of plastic products, with new applications continuously being developed. Also it has been used to produce epoxy resins and polycarbonate plastics for food container. This study was carried out to investigate the effects of bisphenol A on lactation period to dams and F1, Sprague-Dawley females were mated with on 2:1 ratio basis. Various doses of bisphenol A (0, 2, 20, 200, and 2,000 $\mu\textrm{g}$/kg) were daily administered to females for 21 days after parturition. Dams and offsprings were sacrificed at the time of weaning. The results were as follows, 2000 $\mu\textrm{g}$/kg of bisphenol A decreased the dams' body weight at post-partum 18 days and also 200 and 2000 $\mu\textrm{g}$/kg of bisphenol A decreased the body weight of neonates at the days of post-partum 21 days. Bisphenol A increased the relative weights of liver and spleen in male offsprings, depending on the doses. But female offsprings showed high relative organ weights of ovaries, and low relative organ weights of uterine in a some dose-response manners. High dose of bisphenol A induced low viability of neonates exposed during lactation period. The dams treated with bisphenol A showed prematured estrous stage. Bisphenol A was recovered about 21.2% average in serum of dams, and also in offsprings'. The results indicate that the bisphenol A induces estrous cycle during lactation period in dams, also reaches to the of offspring through breast milk. Thus bisphenol A exopsed to dams and neonates via lactation induces some estrogenic and toxic effects.