• Journal of the Korean Society of Manufacturing Process Engineers
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• v.19 no.8
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• pp.15-21
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• 2020

We improved the sound pressure of the speaker and allowed the speaker to rotate 360 degrees to improve the effectiveness of the acoustic type bird repellent system. The prototype of the bird repellent system was developed by evaluating sound pressure characteristics by distance and direction and installing orchards. As a result of the evaluation, the extermination sound pressure increased from a distance of about 30 m to a maximum of 60 m, and through the rotary speaker, the extermination distance could be widened in all directions without specific direction.

• Journal of Microbiology and Biotechnology
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• v.29 no.2
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• pp.304-310
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• 2019

Interleukin-21 is a common ${\gamma}$-chain cytokine that controls the immune responses of B cells, T cells, and natural killer cells. Targeting IL-21 to strengthen the immune system is promising for the development of vaccines as well as anti-infection and anti-tumor therapies. However, the practical application of IL-21 is limited by the high production cost. In this study, we improved IL-21 production by codon optimization and selection of appropriate signal peptide in CHO-K1 cells. Codon-optimized or non-optimized human IL-21 was stably transfected into CHO-K1 cells. IL-21 expression was 10-fold higher for codon-optimized than non-optimized IL-21. We fused five different signal peptides to codon-optimized mature IL-21 and evaluated their effect on IL-21 production. The best result (a 3-fold increase) was obtained using a signal peptide derived from human azurocidin. Furthermore, codon-optimized IL-21 containing the azurocidin signal peptide promoted $IFN-{\gamma}$ secretion and STAT3 phosphorylation in NK-92 cells similar to codon-optimized IL-21 containing original signal peptide. Collectively, these results indicate that codon optimization and azurocidin signal peptides provide an efficient approach for the high-level production of IL-21 as a biopharmaceutical.

• Journal of the Korean Mathematical Society
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• v.45 no.4
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• pp.993-1005
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• 2008

Let {$X,\;X_n;n{\geq}1$} be a sequence of i.i.d. random variables. Set $S_n=X_1+X_2+{\cdots}+X_n,\;M_n=\max_{k{\leq}n}|S_k|,\;n{\geq}1$. Then we obtain that for any -1$\lim\limits_{{\varepsilon}{\searrow}0}\;{\varepsilon}^{2b+2}\sum\limits_{n=1}^\infty\;{\frac {(log\;n)^b}{n^{3/2}}\;E\{M_n-{\varepsilon}{\sigma}\sqrt{n\;log\;n\}+=\frac{2\sigma}{(b+1)(2b+3)}\;E|N|^{2b+3}\sum\limits_{k=0}^\infty\;{\frac{(-1)^k}{(2k+1)^{2b+3}$ if and only if EX=0 and $EX^2={\sigma}^2<{\infty}$.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.14 no.4
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• pp.336-343
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• 2004

This paper reports the first known free vibration data for thin rectangular plates with V-notches. The classical Ritz method is employed with two sets of admissible functions assumed for the transverse vibratory displacements. These sets include (1) mathematically complete algebraic-trigonometric polynomials which guarantee convergence to exact frequencies as sufficient terms are retained, and (2) corner functions which account for the bending moment singularities at the sharp reentrant corner of the Y-notch. Extensive convergence studies summarized herein confirm that the corner functions substantially enhance the convergence and accuracy of nondirectional frequencies for rectangular plates having the V-notch. In this paper, accurate frequencies and normalized contours of vibratory transverse displacement are presented for various notched plates, so that the effect of corner stress singularities may be understood.

• Proceedings of the Technology Innovation Conference
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• 2006.02a
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• pp.248-263
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• 2006

The convergence in telecommunication and broadcasting is one of the most popular topics in these days. For example, the characteristic of IPTV -internet protocol television-is controversial in the extreme. In Korea the IPTV operators are mainly the telecommunication service operators. So it is natural that the IPTV services are categorized to the telecommunication services. But the Broadcasting service providers, especially the CATV providers who can serve the TPS-triple play service- like IPTV players insist that the IPTV should be regulated as a broadcasting service. This paper will analyze whether the regulation in which the IPTV is categorized to one of the broadcasting services is better than the case of telecommunication services. To examine this, the social welfare analysis is conduced and the differential oligopoly market model is used. Together with that, this paper suggests that we can improve the social welfare by the asymmetric regulation between IPTV and D-CA TV. This means that in Korea the IPTV has a weak substitution relation with the D-CA TV and the IPTV should be dealed as a new convergence service that differs from traditional broadcasting services.

• Journal of applied mathematics & informatics
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• v.20 no.1_2
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• pp.465-478
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• 2006

In this paper, we introduce a new class of completely generalized strongly nonlinear quasivariational inequalities and establish its equivalence with a class of fixed point problems by using the resolvent operator technique. Utilizing this equivalence, we develop a three-step iterative scheme with errors, obtain a few existence theorems of solutions for the completely generalized non-linear strongly quasivariational inequality involving relaxed monotone, relaxed Lipschitz, strongly monotone and generalized pseudocontractive mappings and prove some convergence and stability results of the sequence generated by the three-step iterative scheme with errors. Our results include several previously known results as special cases.

• Journal of applied mathematics & informatics
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• v.19 no.1_2
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• pp.527-535
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• 2005

Numerical differentiation is one of the main topics which have been studied by many researchers. If we use the forward difference scheme or the centered difference scheme, the convergence rates to the derivative are O(h) and O($h^2$), respectively. In this paper, using the Lagrange Interpolation, we construct a simple high order numerical differentiation scheme which has the convergence rate O($h^{2k}$) if we have 2k+1 equally spaced nodes. Our scheme is constructive.

• Structural Engineering and Mechanics
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• v.31 no.4
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• pp.383-392
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• 2009

The static and dynamic analyses of simply supported beams are studied by using the U-transformation method and the finite difference method. When the beam is divided into the mesh of equal elements, the mesh may be treated as a periodic structure. After an equivalent cyclic periodic system is established, the difference governing equation for such an equivalent system can be uncoupled by applying the U-transformation. Therefore, a set of single-degree-of-freedom equations is formed. These equations can be used to obtain exact analytical solutions of the deflections, bending moments, buckling loads, natural frequencies and dynamic responses of the beam subjected to particular loads or excitations. When the number of elements approaches to infinity, the exact error expression and the exact convergence rates of the difference solutions are obtained. These exact results cannot be easily derived if other methods are used instead.

• Journal of information and communication convergence engineering
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• v.16 no.2
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• pp.114-124
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• 2018

This paper illustrates a vision-based vehicle positioning method at an intersection to support the C-ITS. It removes the minor shadow that causes the merging problem by simply eliminating the fractional parts of a quotient image. In order to separate the occlusion, it firstly performs the distance transform to analyze the contents of the single foreground object to find seeds, each of which represents one vehicle. Then, it applies the watershed to find the natural border of two cars. In addition, a general vehicle model and the corresponding space estimation method are proposed. For performance evaluation, the corresponding ground truth data are read and compared with the vision-based detected data. In addition, two criteria, IOU and DEER, are defined to measure the accuracy of the extracted data. The evaluation result shows that the average value of IOU is 0.65 with the hit ratio of 97%. It also shows that the average value of DEER is 0.0467, which means the positioning error is 32.7 centimeters.

• Journal of Korea Multimedia Society
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• v.22 no.2
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• pp.250-259
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• 2019

Big data processing technology and artificial intelligence (AI) are increasingly attracting attention. Natural language processing is an important research area of artificial intelligence. In this paper, we use Korean news articles to extract topic distributions in documents and word distribution vectors in topics through LDA-based Topic Modeling. Then, we use Word2vec to vector words, and generate a weight matrix to derive the relevance SCORE considering the semantic relationship between the words. We propose a way to recommend documents in order of high score.